{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T12:18:34Z","timestamp":1791461914384,"version":"4.3.4"},"reference-count":43,"publisher":"Elsevier BV","issue":"8","license":[{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100002858","name":"China Postdoctoral Science Foundation","doi-asserted-by":"publisher","award":["2019M660921"],"award-info":[{"award-number":["2019M660921"]}],"id":[{"id":"10.13039\/501100002858","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002858","name":"China Postdoctoral Science Foundation","doi-asserted-by":"publisher","award":["2020T130436"],"award-info":[{"award-number":["2020T130436"]}],"id":[{"id":"10.13039\/501100002858","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006606","name":"Natural Science Foundation of Tianjin City","doi-asserted-by":"publisher","award":["19JCYBJC26600"],"award-info":[{"award-number":["19JCYBJC26600"]}],"id":[{"id":"10.13039\/501100006606","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","dldjournalonline.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Digestive and Liver Disease"],"published-print":{"date-parts":[[2022,8]]},"DOI":"10.1016\/j.dld.2021.09.015","type":"journal-article","created":{"date-parts":[[2021,10,14]],"date-time":"2021-10-14T03:50:51Z","timestamp":1634183451000},"page":"1109-1116","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"title":["Development and validation of a novel nomogram and risk score for biliary atresia in patients with cholestasis"],"prefix":"10.1016","volume":"54","author":[{"given":"Yakun","family":"Liu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruone","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dongyang","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kai","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenjun","family":"Tu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chunhui","family":"Peng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4098-9653","authenticated-orcid":false,"given":"Yajun","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.dld.2021.09.015_bib0001","doi-asserted-by":"crossref","first-page":"1704","DOI":"10.1016\/S0140-6736(09)60946-6","article-title":"Biliary atresia","volume":"374","author":"Hartley","year":"2009","journal-title":"Lancet"},{"key":"10.1016\/j.dld.2021.09.015_bib0002","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1097\/SLA.0b013e3182300950","article-title":"The anatomic pattern of biliary atresia identified at time of Kasai hepatoportoenterostomy and early postoperative clearance of jaundice are significant predictors of transplant-free survival","volume":"254","author":"Superina","year":"2011","journal-title":"Ann Surg"},{"key":"10.1016\/j.dld.2021.09.015_bib0003","doi-asserted-by":"crossref","first-page":"1163","DOI":"10.1002\/hep.29905","article-title":"Biliary atresia: clinical and research challenges for the twenty-first century","volume":"68","author":"Bezerra","year":"2018","journal-title":"Hepatology"},{"key":"10.1016\/j.dld.2021.09.015_bib0004","doi-asserted-by":"crossref","first-page":"1209","DOI":"10.1016\/j.jhep.2013.01.040","article-title":"Improving outcomes of biliary atresia: French national series 1986-2009","volume":"58","author":"Chardot","year":"2013","journal-title":"J Hepatol"},{"key":"10.1016\/j.dld.2021.09.015_bib0005","doi-asserted-by":"crossref","first-page":"1280","DOI":"10.1542\/peds.2008-1949","article-title":"Impact of age at Kasai operation on its results in late childhood and adolescence: a rational basis for biliary atresia screening","volume":"123","author":"Serinet","year":"2009","journal-title":"Pediatrics"},{"key":"10.1016\/j.dld.2021.09.015_bib0006","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1097\/MPG.0b013e318282a913","article-title":"International incidence and outcomes of biliary atresia","volume":"56","author":"Jimenez-Rivera","year":"2013","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"10.1016\/j.dld.2021.09.015_bib0007","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1016\/j.jpeds.2005.12.054","article-title":"A multicenter study of the outcome of biliary atresia in the United States, 1997 to 2000","volume":"148","author":"Shneider","year":"2006","journal-title":"J Pediatr"},{"key":"10.1016\/j.dld.2021.09.015_bib0008","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1148\/radiol.2018172390","article-title":"Risk estimation for biliary atresia in patients with neonatal cholestasis: development and validation of a risk score","volume":"288","author":"Kim","year":"2018","journal-title":"Radiology"},{"key":"10.1016\/j.dld.2021.09.015_bib0009","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/j.ebiom.2018.07.025","article-title":"Development and validation of novel diagnostic models for biliary atresia in a large cohort of chinese patients","volume":"34","author":"Dong","year":"2018","journal-title":"EBioMedicine"},{"key":"10.1016\/j.dld.2021.09.015_bib0010","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1016\/j.jhep.2014.03.016","article-title":"Design and validation of a diagnostic score for biliary atresia","volume":"61","author":"El-Guindi","year":"2014","journal-title":"J Hepatol"},{"key":"10.1016\/j.dld.2021.09.015_bib0011","article-title":"Development and validation of a nomogram incorporating ultrasonic and elastic findings for the preoperative diagnosis of biliary atresia","volume":"21","author":"Wang","year":"2020","journal-title":"Acad Radiol"},{"key":"10.1016\/j.dld.2021.09.015_bib0012","doi-asserted-by":"crossref","DOI":"10.1016\/j.aohep.2020.09.007","article-title":"Temporal histopathological changes in biliary atresia: a perspective for rapid fibrosis progression","volume":"21","author":"El-Araby","year":"2021","journal-title":"Ann Hepatol"},{"key":"10.1016\/j.dld.2021.09.015_bib0013","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1186\/s12887-020-02172-z","article-title":"Combination of gamma-glutamyl transferase and liver stiffness measurement for biliary atresia screening at different ages: a retrospective analysis of 282 infants","volume":"20","author":"Shen","year":"2020","journal-title":"BMC Pediatr"},{"key":"10.1016\/j.dld.2021.09.015_bib0014","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1097\/MPG.0000000000001168","article-title":"Value of gamma-glutamyl transpeptidase for diagnosis of biliary atresia by correlation with age","volume":"63","author":"Chen","year":"2016","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"10.1016\/j.dld.2021.09.015_bib0015","doi-asserted-by":"crossref","first-page":"n8462","DOI":"10.1126\/scitranslmed.aan8462","article-title":"Large-scale proteomics identifies MMP-7 as a sentinel of epithelial injury and of biliary atresia","volume":"9","author":"Lertudomphonwanit","year":"2017","journal-title":"Sci Transl Med"},{"key":"10.1016\/j.dld.2021.09.015_bib0016","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1111\/j.1651-2227.1998.tb01750.x","article-title":"Gallbladder volume and contractility in term and preterm neonates: normal values and clinical applications in ultrasonography","volume":"87","author":"Ho","year":"1998","journal-title":"Acta Paediatr"},{"key":"10.1016\/j.dld.2021.09.015_bib0017","doi-asserted-by":"crossref","first-page":"1233","DOI":"10.1002\/hep.22182","article-title":"Universal screening for biliary atresia using an infant stool color card in Taiwan","volume":"47","author":"Hsiao","year":"2008","journal-title":"Hepatology"},{"key":"10.1016\/j.dld.2021.09.015_bib0018","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1097\/MPG.0000000000001334","article-title":"Guideline for the evaluation of cholestatic jaundice in infants: joint recommendations of the north american society for pediatric gastroenterology, hepatology, and nutrition and the european society for pediatric gastroenterology","volume":"64","author":"Fawaz","year":"2017","journal-title":"Hepatol Nutr J Pediatr Gastroenterol Nutr"},{"key":"10.1016\/j.dld.2021.09.015_bib0019","doi-asserted-by":"crossref","first-page":"876","DOI":"10.1002\/lt.21711","article-title":"Prognostic value of computerized quantification of liver fibrosis in children with biliary atresia","volume":"15","author":"Pape","year":"2009","journal-title":"Liver Transpl"},{"key":"10.1016\/j.dld.2021.09.015_bib0020","doi-asserted-by":"crossref","first-page":"63","DOI":"10.4103\/0189-6725.182558","article-title":"Diagnostic value of anti-smooth muscle antibodies and liver enzymes in differentiation of extrahepatic biliary atresia and idiopathic neonatal hepatitis","volume":"13","author":"Rafeey","year":"2016","journal-title":"Afr J Paediatr Surg"},{"key":"10.1016\/j.dld.2021.09.015_bib0021","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1258\/0004563021901685","article-title":"Gamma-glutamyltransferase: value of its measurement in paediatrics","volume":"39","author":"Cabrera-Abreu","year":"2002","journal-title":"Ann Clin Biochem"},{"key":"10.1016\/j.dld.2021.09.015_bib0022","doi-asserted-by":"crossref","first-page":"2125","DOI":"10.1002\/hep.25936","article-title":"Accuracy of real-time shear wave elastography for assessing liver fibrosis in chronic hepatitis C: a pilot study","volume":"56","author":"Ferraioli","year":"2012","journal-title":"Hepatology"},{"key":"10.1016\/j.dld.2021.09.015_bib0023","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1007\/s00247-014-3149-z","article-title":"Shear wave elastography helps differentiate biliary atresia from other neonatal\/infantile liver diseases","volume":"45","author":"Leschied","year":"2015","journal-title":"Pediatr Radiol"},{"key":"10.1016\/j.dld.2021.09.015_bib0024","doi-asserted-by":"crossref","DOI":"10.1007\/s00247-021-05024-9","article-title":"Ultrasound shear wave elastography: does it add value to gray-scale ultrasound imaging in differentiating biliary atresia from other causes of neonatal jaundice?","author":"Sandberg","year":"2021","journal-title":"Pediatr Radiol"},{"key":"10.1016\/j.dld.2021.09.015_bib0025","doi-asserted-by":"crossref","DOI":"10.1007\/s00247-020-04959-9","article-title":"Diagnostic accuracy of two-dimensional shear wave elastography in detecting hepatic fibrosis in children with autoimmune hepatitis, biliary atresia and other chronic liver diseases","author":"Galina","year":"2021","journal-title":"Pediatr Radiol"},{"key":"10.1016\/j.dld.2021.09.015_bib0026","doi-asserted-by":"crossref","DOI":"10.3348\/kjr.2020.0885","article-title":"Two-dimensional shear wave elastography predicts liver fibrosis in jaundiced infants with suspected biliary atresia: a prospective study","author":"Chen","year":"2021","journal-title":"Korean J Radiol"},{"key":"10.1016\/j.dld.2021.09.015_bib0027","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1148\/radiol.2452061093","article-title":"Hepatic arterial diameter measured with US: adjunct for US diagnosis of biliary atresia","volume":"245","author":"Kim","year":"2007","journal-title":"Radiology"},{"key":"10.1016\/j.dld.2021.09.015_bib0028","doi-asserted-by":"crossref","first-page":"1555","DOI":"10.1016\/S0022-3468(97)90451-6","article-title":"A new diagnostic approach to biliary atresia with emphasis on the ultrasonographic triangular cord sign: comparison of ultrasonography, hepatobiliary scintigraphy, and liver needle biopsy in the evaluation of infantile cholestasis","volume":"32","author":"Park","year":"1997","journal-title":"J Pediatr Surg"},{"key":"10.1016\/j.dld.2021.09.015_bib0029","doi-asserted-by":"crossref","first-page":"W438","DOI":"10.2214\/AJR.10.5180","article-title":"Role of abdominal sonography in the preoperative diagnosis of extrahepatic biliary atresia in infants younger than 90 days","volume":"196","author":"Mittal","year":"2011","journal-title":"AJR Am J Roentgenol"},{"key":"10.1016\/j.dld.2021.09.015_bib0030","doi-asserted-by":"crossref","first-page":"2093","DOI":"10.1016\/j.jpedsurg.2007.08.032","article-title":"Can biliary atresia be diagnosed by ultrasonography alone?","volume":"42","author":"Takamizawa","year":"2007","journal-title":"J Pediatr Surg"},{"key":"10.1016\/j.dld.2021.09.015_bib0031","doi-asserted-by":"crossref","first-page":"2027","DOI":"10.1002\/jum.14234","article-title":"Diagnostic performance of sonographic features in patients with biliary atresia: a systematic review and meta-analysis","volume":"36","author":"Yoon","year":"2017","journal-title":"J Ultrasound Med"},{"key":"10.1016\/j.dld.2021.09.015_bib0032","doi-asserted-by":"crossref","first-page":"1771","DOI":"10.1007\/s00330-017-5092-5","article-title":"Early US findings of biliary atresia in infants younger than 30 days","volume":"28","author":"Hwang","year":"2018","journal-title":"Eur Radiol"},{"key":"10.1016\/j.dld.2021.09.015_bib0033","article-title":"The utility of shear wave elastography and serum biomarkers for diagnosing biliary atresia and predicting clinical outcomes","author":"Liu","year":"2021","journal-title":"Eur J Pediatr"},{"key":"10.1016\/j.dld.2021.09.015_bib0034","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1016\/S1499-3872(13)60065-X","article-title":"The diagnostic value of high-frequency ultrasonography in biliary atresia","volume":"12","author":"Jiang","year":"2013","journal-title":"Hepatobiliary Pancreat Dis Int"},{"key":"10.1016\/j.dld.2021.09.015_bib0035","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1148\/radiol.2443061051","article-title":"Biliary atresia: US diagnosis","volume":"244","author":"Humphrey","year":"2007","journal-title":"Radiology"},{"key":"10.1016\/j.dld.2021.09.015_bib0036","doi-asserted-by":"crossref","first-page":"1387","DOI":"10.2214\/ajr.181.5.1811387","article-title":"Sonographic diagnosis of biliary atresia in pediatric patients using the \"triangular cord\" sign versus gallbladder length and contraction","volume":"181","author":"Kanegawa","year":"2003","journal-title":"AJR Am J Roentgenol"},{"key":"10.1016\/j.dld.2021.09.015_bib0037","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1016\/j.jpeds.2014.12.063","article-title":"Stool color card screening for early detection of biliary atresia and long-term native liver survival: a 19-year cohort study in Japan","volume":"166","author":"Gu","year":"2015","journal-title":"J Pediatr"},{"key":"10.1016\/j.dld.2021.09.015_bib0038","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1007\/s12519-016-0061-7","article-title":"Modified stool color card with digital images was efficient and feasible for early detection of biliary atresia-a pilot study in Beijing, China","volume":"12","author":"Kong","year":"2016","journal-title":"World J Pediatr"},{"key":"10.1016\/j.dld.2021.09.015_bib0039","doi-asserted-by":"crossref","first-page":"592","DOI":"10.1097\/MPG.0b013e3182616916","article-title":"Risk factors for developing transient neonatal cholestasis","volume":"55","author":"Champion","year":"2012","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"10.1016\/j.dld.2021.09.015_bib0040","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1055\/s-2007-985070","article-title":"Intestinal failure-associated liver disease: management and treatment strategies past, present, and future","volume":"27","author":"Carter","year":"2007","journal-title":"Semin Liver Dis"},{"key":"10.1016\/j.dld.2021.09.015_bib0041","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1007\/BF02752271","article-title":"AIIMS clinical score: a reliable aid to distinguish neonatal hepatitis from extra hepatic biliary atresia","volume":"68","author":"Gupta","year":"2001","journal-title":"Indian J Pediatr"},{"key":"10.1016\/j.dld.2021.09.015_bib0042","first-page":"212","article-title":"Atypical morphologic presentation of biliary atresia and value of serial liver biopsies","volume":"34","author":"Azar","year":"2002","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"10.1016\/j.dld.2021.09.015_bib0043","doi-asserted-by":"crossref","first-page":"985","DOI":"10.1016\/j.jhep.2014.11.042","article-title":"A scoring system for biliary atresia: is this the right one?","volume":"62","author":"Sciveres","year":"2015","journal-title":"J Hepatol"}],"container-title":["Digestive and Liver Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1590865821007842?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1590865821007842?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T04:19:32Z","timestamp":1761625172000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1590865821007842"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,8]]},"references-count":43,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2022,8]]}},"alternative-id":["S1590865821007842"],"URL":"https:\/\/doi.org\/10.1016\/j.dld.2021.09.015","relation":{},"ISSN":["1590-8658"],"issn-type":[{"value":"1590-8658","type":"print"}],"subject":[],"published":{"date-parts":[[2022,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Development and validation of a novel nomogram and risk score for biliary atresia in patients with cholestasis","name":"articletitle","label":"Article Title"},{"value":"Digestive and Liver Disease","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.dld.2021.09.015","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Editrice Gastroenterologica Italiana S.r.l. Published by Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}