{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T04:24:01Z","timestamp":1761625441810,"version":"build-2065373602"},"reference-count":21,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","dldjournalonline.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Digestive and Liver Disease"],"published-print":{"date-parts":[[2022,1]]},"DOI":"10.1016\/j.dld.2021.09.018","type":"journal-article","created":{"date-parts":[[2021,10,28]],"date-time":"2021-10-28T20:41:24Z","timestamp":1635453684000},"page":"54-55","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"title":["Direct oral anticoagulants for portal vein thrombosis in cirrhosis: Good news from meta-analysis?"],"prefix":"10.1016","volume":"54","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1588-2643","authenticated-orcid":false,"given":"M.","family":"Primignani","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Tosetti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.dld.2021.09.018_bib0001","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.dld.2021.07.039","article-title":"Efficacy and safety of direct oral anticoagulants versus vitamin K antagonist for portal vein thrombosis in cirrhosis: a systematic review and meta-analysis","volume":"54","author":"Koh","year":"2022","journal-title":"Dig Liver Dis"},{"issue":"5","key":"10.1016\/j.dld.2021.09.018_bib0002","doi-asserted-by":"crossref","first-page":"694","DOI":"10.1111\/liv.13285","article-title":"Antithrombotic treatment with direct-acting oral anticoagulants in patients with splanchnic vein thrombosis and cirrhosis","volume":"37","author":"De Gottardi","year":"2017","journal-title":"Liver Int"},{"issue":"1","key":"10.1016\/j.dld.2021.09.018_bib0003","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1111\/hepr.12895","article-title":"Efficacy and safety of edoxaban for treatment of portal vein thrombosis following danaparoid sodium in patients with liver cirrhosis","volume":"48","author":"Nagaoka","year":"2018","journal-title":"Hepatol Res"},{"key":"10.1016\/j.dld.2021.09.018_bib0004","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/j.vph.2018.05.002","article-title":"Randomized controlled trial of rivaroxaban versus warfarin in the management of acute non-neoplastic portal vein thrombosis","volume":"113","author":"Hanafy","year":"2019","journal-title":"Vascul Pharmacol"},{"issue":"6","key":"10.1016\/j.dld.2021.09.018_bib0005","doi-asserted-by":"crossref","first-page":"1721","DOI":"10.1007\/s10620-015-4012-2","article-title":"Direct oral anticoagulants in cirrhosis patients pose similar risks of bleeding when compared to traditional anticoagulation","volume":"61","author":"Intagliata","year":"2016","journal-title":"Dig Dis Sci"},{"issue":"4","key":"10.1016\/j.dld.2021.09.018_bib0006","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1111\/ejh.12844","article-title":"The efficacy and safety of direct oral anticoagulants vs traditional anticoagulants in cirrhosis","volume":"98","author":"Hum","year":"2017","journal-title":"Eur J Haematol"},{"issue":"6","key":"10.1016\/j.dld.2021.09.018_bib0007","doi-asserted-by":"crossref","first-page":"911","DOI":"10.1097\/MEG.0000000000001958","article-title":"Evaluation of the efficacy and safety of direct oral anticoagulants in the treatment of portal vein thrombosis","volume":"33","author":"Ilcewicz","year":"2021","journal-title":"Eur J Gastroenterol Hepatol"},{"key":"10.1016\/j.dld.2021.09.018_bib0008","first-page":"115","article-title":"S1085 Direct oral anticoagulants and warfarin in patients with cirrhosis and portal vein thrombosis: a comparison of outcomes","author":"Joseph","year":"2020","journal-title":"Off J Am Coll Gastroenterol"},{"issue":"2","key":"10.1016\/j.dld.2021.09.018_bib0009","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1007\/s11239-019-02035-0","article-title":"Direct oral anticoagulants and warfarin in patients with cirrhosis: a comparison of outcomes","volume":"50","author":"Davis","year":"2020","journal-title":"J Thromb Thrombolysis"},{"key":"10.1016\/j.dld.2021.09.018_bib0010","article-title":"efficacy and safety of edoxaban for treatment of portal vein thrombosis in patients with liver cirrhosis","volume":"68","author":"Yuko","year":"2018","journal-title":"Hepatology"},{"issue":"13\u201314","key":"10.1016\/j.dld.2021.09.018_bib0011","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1007\/s00508-018-1351-y","article-title":"Anticoagulation in non-malignant portal vein thrombosis is safe and improves hepatic function","volume":"130","author":"Scheiner","year":"2018","journal-title":"Wien Klin Wochenschr"},{"key":"10.1016\/j.dld.2021.09.018_bib0012","first-page":"75","article-title":"The efficacy and safety of anticoagulant treatment for portal vein thrombosis","volume":"28","author":"Irina","year":"2019","journal-title":"J Gastrointest Liver Dis"},{"issue":"9","key":"10.1016\/j.dld.2021.09.018_bib0013","doi-asserted-by":"crossref","first-page":"2159","DOI":"10.1111\/liv.14992","article-title":"Safety of direct oral anticoagulants in patients with advanced liver disease","volume":"41","author":"Semmler","year":"2021","journal-title":"Liver Int"},{"issue":"7","key":"10.1016\/j.dld.2021.09.018_bib0014","doi-asserted-by":"crossref","first-page":"1436","DOI":"10.1016\/j.cgh.2020.08.007","article-title":"Rates of bleeding and discontinuation of direct oral anticoagulants in patients with decompensated cirrhosis","volume":"19","author":"Mort","year":"2021","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1016\/j.dld.2021.09.018_bib0015","doi-asserted-by":"crossref","first-page":"1318","DOI":"10.1111\/tri.13353","article-title":"Mortality in liver transplant recipients with portal vein thrombosis \u2013 an updated meta-analysis","volume":"31","author":"Zanetto","year":"2018","journal-title":"Transpl Int"},{"issue":"1","key":"10.1016\/j.dld.2021.09.018_bib0016","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1002\/hep.31646","article-title":"Vascular liver disorders, portal vein thrombosis, and procedural bleeding in patients with liver disease: 2020 practice guidance by the American Association for the Study of Liver Diseases","volume":"73","author":"Northup","year":"2021","journal-title":"Hepatology"},{"key":"10.1016\/j.dld.2021.09.018_bib0017","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1016\/j.jhep.2015.05.022","article-title":"Expanding consensus in portal hypertension. Report of the Baveno VI Consensus Workshop: stratifying risk and individualizing care for portal hypertension","volume":"63","author":"de Franchis","year":"2015","journal-title":"J Hepatol"},{"issue":"1","key":"10.1016\/j.dld.2021.09.018_bib0018","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/j.jhep.2015.07.040","article-title":"EASL Clinical Practice Guidelines: vascular diseases of the liver","volume":"64","year":"2016","journal-title":"J Hepatol"},{"key":"10.1016\/j.dld.2021.09.018_bib0019","doi-asserted-by":"crossref","first-page":"1435","DOI":"10.1002\/hep.27350","article-title":"Decreased in vitro anticoagulant potency of Rivaroxaban and Apixaban in plasma from patients with cirrhosis","volume":"61","author":"Potze","year":"2015","journal-title":"Hepatology"},{"key":"10.1016\/j.dld.2021.09.018_bib0020","doi-asserted-by":"crossref","first-page":"e88390","DOI":"10.1371\/journal.pone.0088390","article-title":"Differential in vitro inhibition of thrombin generation by anticoagulant drugs in plasma from patients with cirrhosis","volume":"9","author":"Potze","year":"2014","journal-title":"PLoS ONE"},{"issue":"1253\u20131260","key":"10.1016\/j.dld.2021.09.018_bib0021","first-page":"e4","article-title":"Enoxaparin prevents portal vein thrombosis and liver decompensation in patients with advanced cirrhosis","volume":"143","author":"Villa","year":"2012","journal-title":"Gastroenterology"}],"container-title":["Digestive and Liver Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1590865821008057?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1590865821008057?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T04:17:05Z","timestamp":1761625025000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1590865821008057"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,1]]},"references-count":21,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2022,1]]}},"alternative-id":["S1590865821008057"],"URL":"https:\/\/doi.org\/10.1016\/j.dld.2021.09.018","relation":{},"ISSN":["1590-8658"],"issn-type":[{"type":"print","value":"1590-8658"}],"subject":[],"published":{"date-parts":[[2022,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Direct oral anticoagulants for portal vein thrombosis in cirrhosis: Good news from meta-analysis?","name":"articletitle","label":"Article Title"},{"value":"Digestive and Liver Disease","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.dld.2021.09.018","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"simple-article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Editrice Gastroenterologica Italiana S.r.l. Published by Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}