{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T19:34:15Z","timestamp":1789500855934,"version":"build-2803163510"},"reference-count":57,"publisher":"Elsevier BV","issue":"7","license":[{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,4,10]],"date-time":"2025-04-10T00:00:00Z","timestamp":1744243200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","dldjournalonline.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Digestive and Liver Disease"],"published-print":{"date-parts":[[2025,7]]},"DOI":"10.1016\/j.dld.2025.04.008","type":"journal-article","created":{"date-parts":[[2025,4,26]],"date-time":"2025-04-26T23:04:07Z","timestamp":1745708647000},"page":"1372-1376","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"title":["Sex differences in hepatic encephalopathy: addressing the knowledge gap"],"prefix":"10.1016","volume":"57","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6761-4969","authenticated-orcid":false,"given":"Lucia","family":"Lapenna","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manuela","family":"Merli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-4601-2974","authenticated-orcid":false,"given":"Marta","family":"Cilla","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0000-1076","authenticated-orcid":false,"given":"Valentina","family":"Cossiga","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2630-7054","authenticated-orcid":false,"given":"Annarosa","family":"Floreani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Federica","family":"Invernizzi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2566-3041","authenticated-orcid":false,"given":"Pierluigi","family":"Toniutto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrizia","family":"Burra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"2","key":"10.1016\/j.dld.2025.04.008_bib0001","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1016\/j.dld.2018.11.035","article-title":"Hepatic encephalopathy 2018: a clinical practice guideline by the Italian association for the study of the liver (AISF)","volume":"51","author":"Montagnese","year":"2019","journal-title":"Dig Liver Dis"},{"issue":"Suppl 1","key":"10.1016\/j.dld.2025.04.008_bib0002","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1007\/s40265-018-1019-y","article-title":"Impact of hepatic encephalopathy in cirrhosis on quality-of-life issues","volume":"79","author":"Montagnese","year":"2019","journal-title":"Drugs"},{"issue":"4","key":"10.1016\/j.dld.2025.04.008_bib0003","doi-asserted-by":"crossref","DOI":"10.14309\/ctg.0000000000000159","article-title":"Psychological burden of hepatic encephalopathy on patients and caregivers","volume":"11","author":"Fabrellas","year":"2020","journal-title":"Clin Transl Gastroenterol"},{"issue":"6","key":"10.1016\/j.dld.2025.04.008_bib0004","doi-asserted-by":"crossref","first-page":"1227","DOI":"10.1007\/s11011-024-01384-x","article-title":"The social and psychological impact of hepatic encephalopathy","volume":"39","author":"S\u00f8rensen","year":"2024","journal-title":"Metab Brain Dis"},{"issue":"6","key":"10.1016\/j.dld.2025.04.008_bib0005","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1080\/028418699432905","article-title":"Illness-related distress: Does it mean the same for men and women? Gender aspects in cancer patients\u2019 distress and adjustment","volume":"38","author":"Keller","year":"1999","journal-title":"Acta Oncol"},{"issue":"3","key":"10.1016\/j.dld.2025.04.008_bib0006","doi-asserted-by":"crossref","first-page":"718","DOI":"10.1111\/jgh.13917","article-title":"Minimal hepatic encephalopathy identifies patients at risk of faster cirrhosis progression","volume":"33","author":"Ampuero","year":"2018","journal-title":"J Gastroenterol Hepatol"},{"issue":"12","key":"10.1016\/j.dld.2025.04.008_bib0007","doi-asserted-by":"crossref","first-page":"2017","DOI":"10.14309\/ajg.0000000000000762","article-title":"Incidence and bedside predictors of the first episode of overt hepatic encephalopathy in patients with cirrhosis","volume":"115","author":"Tapper","year":"2020","journal-title":"Am J Gastroenterol"},{"issue":"1","key":"10.1016\/j.dld.2025.04.008_bib0008","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1097\/MCG.0000000000001192","article-title":"Gender differences among patients hospitalized with cirrhosis in the United States","volume":"54","author":"Rubin","year":"2020","journal-title":"J Clin Gastroenterol"},{"issue":"4","key":"10.1016\/j.dld.2025.04.008_bib0009","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1038\/ajg.2016.29","article-title":"Cognitive impairment predicts the occurrence of hepatic encephalopathy after transjugular intrahepatic portosystemic shunt","volume":"111","author":"Nardelli","year":"2016","journal-title":"Am J Gastroenterol"},{"issue":"3","key":"10.1016\/j.dld.2025.04.008_bib0010","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1002\/hep.32453","article-title":"Concurrent large spontaneous portosystemic shunt embolization for the prevention of overt hepatic encephalopathy after TIPS: a randomized controlled trial","volume":"76","author":"Lv","year":"2022","journal-title":"Hepatology"},{"issue":"4","key":"10.1016\/j.dld.2025.04.008_bib0011","doi-asserted-by":"crossref","first-page":"1454","DOI":"10.1007\/s00261-023-03813-4","article-title":"Low adipose tissue index as an indicator of hepatic encephalopathy in cirrhotic patients following transjugular intrahepatic portosystemic shunt","volume":"48","author":"Wang","year":"2023","journal-title":"Abdom Radiol"},{"issue":"3","key":"10.1016\/j.dld.2025.04.008_bib0012","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1016\/j.jhep.2022.06.001","article-title":"European association for the study of the liver. EASL clinical practice guidelines on the management of hepatic encephalopathy","volume":"77","year":"2022","journal-title":"J Hepatol"},{"issue":"7","key":"10.1016\/j.dld.2025.04.008_bib0013","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1016\/j.cgh.2011.03.017","article-title":"A simplified psychometric evaluation for the diagnosis of minimal hepatic encephalopathy","volume":"9","author":"Riggio","year":"2011","journal-title":"Clin Gastroenterol Hepatol"},{"issue":"6","key":"10.1016\/j.dld.2025.04.008_bib0014","doi-asserted-by":"crossref","DOI":"10.14309\/ctg.0000000000000172","article-title":"Outcome prediction of covert hepatic encephalopathy in liver cirrhosis: comparison of four testing strategies","volume":"11","author":"Labenz","year":"2020","journal-title":"Clin Transl Gastroenterol"},{"issue":"1","key":"10.1016\/j.dld.2025.04.008_bib0015","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1038\/ajg.2015.377","article-title":"Diagnosis of minimal hepatic encephalopathy using stroop EncephalApp: a multicenter US-based, norm-based study","volume":"111","author":"Allampati","year":"2016","journal-title":"Am J Gastroenterol"},{"issue":"4","key":"10.1016\/j.dld.2025.04.008_bib0016","first-page":"690","article-title":"Prevalence and characteristics of covert\/minimal hepatic encephalopathy in patients with liver cirrhosis: a systematic review and meta-analysis","volume":"119","author":"Lv","year":"2024","journal-title":"Am J Gastroenterol"},{"issue":"6","key":"10.1016\/j.dld.2025.04.008_bib0017","doi-asserted-by":"crossref","DOI":"10.1001\/jamanetworkopen.2019.6412","article-title":"Trends in characteristics, mortality, and other outcomes of patients with newly diagnosed cirrhosis","volume":"2","author":"Orman","year":"2019","journal-title":"JAMA Netw Open"},{"issue":"1","key":"10.1016\/j.dld.2025.04.008_bib0018","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1016\/j.jhep.2020.03.039","article-title":"A new definition for metabolic dysfunction-associated fatty liver disease: an international expert consensus statement","volume":"73","author":"Eslam","year":"2020","journal-title":"J Hepatol"},{"issue":"4","key":"10.1016\/j.dld.2025.04.008_bib0019","doi-asserted-by":"crossref","DOI":"10.3390\/jcm10040673","article-title":"Cognitive dysfunction in non-alcoholic fatty liver disease-current knowledge, mechanisms and perspectives","volume":"10","author":"Kj\u00e6rgaard","year":"2021","journal-title":"J Clin Med"},{"key":"10.1016\/j.dld.2025.04.008_bib0020","article-title":"A narrative review about cognitive impairment in metabolic dysfunction-associated liver disease (MASLD): another matter to face through a holistic approach","author":"Meroni","year":"2024","journal-title":"J Adv Res"},{"key":"10.1016\/j.dld.2025.04.008_bib0021","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1016\/B978-0-444-62619-6.00034-3","article-title":"Hepatic encephalopathy in alcoholic cirrhosis","volume":"125","author":"Butterworth","year":"2014","journal-title":"Handb Clin Neurol"},{"issue":"4","key":"10.1016\/j.dld.2025.04.008_bib0022","doi-asserted-by":"crossref","first-page":"660","DOI":"10.1111\/acer.13605","article-title":"Effects of alcohol on the brain in cirrhosis: beyond hepatic encephalopathy","volume":"42","author":"Davis","year":"2018","journal-title":"Alcohol Clin Exp Res"},{"issue":"12","key":"10.1016\/j.dld.2025.04.008_bib0023","doi-asserted-by":"crossref","first-page":"1136","DOI":"10.1212\/WNL.0000000000002498","article-title":"Nonalcoholic fatty liver disease is associated with cognitive function in adults","volume":"86","author":"Seo","year":"2016","journal-title":"Neurology"},{"issue":"1","key":"10.1016\/j.dld.2025.04.008_bib0024","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/j.cld.2011.12.008","article-title":"Hepatic encephalopathy after transjugular intrahepatic portosystemic shunt","volume":"16","author":"Riggio","year":"2012","journal-title":"Clin Liver Dis"},{"issue":"2","key":"10.1016\/j.dld.2025.04.008_bib0025","doi-asserted-by":"crossref","DOI":"10.3390\/jcm10020298","article-title":"Hepatic encephalopathy in the 21st century: still an emerging topic","volume":"10","author":"Ridola","year":"2021","journal-title":"J Clin Med"},{"issue":"5","key":"10.1016\/j.dld.2025.04.008_bib0026","doi-asserted-by":"crossref","first-page":"794","DOI":"10.1016\/j.jceh.2023.01.017","article-title":"New indications for TIPSs: What do we know so far?","volume":"13","author":"Lapenna","year":"2023","journal-title":"J Clin Exp Hepatol"},{"issue":"1 Pt 1","key":"10.1016\/j.dld.2025.04.008_bib0027","first-page":"46","article-title":"Portosystemic encephalopathy after transjugular intrahepatic portosystemic shunt: results of a prospective controlled study","volume":"20","author":"Sanyal","year":"1994","journal-title":"Hepatology"},{"issue":"3","key":"10.1016\/j.dld.2025.04.008_bib0028","doi-asserted-by":"crossref","first-page":"578","DOI":"10.1007\/BF02282344","article-title":"Hepatic encephalopathy after transjugular intrahepatic portosystemic shunt. Incidence and risk factors","volume":"41","author":"Riggio","year":"1996","journal-title":"Dig Dis Sci"},{"issue":"5","key":"10.1016\/j.dld.2025.04.008_bib0029","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1080\/0036552031000-762","article-title":"Intractable hepatic encephalopathy after tips with polytetrafluoroethylene-covered stent-graft","volume":"38","author":"Riggio","year":"2003","journal-title":"Scand J Gastroenterol"},{"issue":"5","key":"10.1016\/j.dld.2025.04.008_bib0030","doi-asserted-by":"crossref","first-page":"674","DOI":"10.1016\/j.jhep.2004.12.028","article-title":"Pharmacological prophylaxis of hepatic encephalopathy after transjugular intrahepatic portosystemic shunt: a randomized controlled study","volume":"42","author":"Riggio","year":"2005","journal-title":"J Hepatol"},{"issue":"21","key":"10.1016\/j.dld.2025.04.008_bib0031","doi-asserted-by":"crossref","DOI":"10.3390\/jcm12216758","article-title":"Transjugular intrahepatic portosystemic shunt: devices evolution, technical tips and future perspectives","volume":"12","author":"Saltini","year":"2023","journal-title":"J Clin Med"},{"issue":"1","key":"10.1016\/j.dld.2025.04.008_bib0032","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1111\/1751-2980.12957","article-title":"Risk factors for overt hepatic encephalopathy after transjugular intrahepatic portosystemic shunt creation in patients with liver cirrhosis","volume":"22","author":"Tong","year":"2021","journal-title":"J Dig Dis"},{"issue":"6","key":"10.1016\/j.dld.2025.04.008_bib0033","doi-asserted-by":"crossref","first-page":"934","DOI":"10.1016\/j.cgh.2016.10.028","article-title":"Sarcopenia is risk factor for development of hepatic encephalopathy after transjugular intrahepatic portosystemic shunt placement","volume":"15","author":"Nardelli","year":"2017","journal-title":"Clin Gastroenterol Hepatol"},{"issue":"1","key":"10.1016\/j.dld.2025.04.008_bib0034","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-023-42061-w","article-title":"A novel nomogram predicting overt hepatic encephalopathy after transjugular intrahepatic portosystemic shunt in portal hypertension patients","volume":"13","author":"Liao","year":"2023","journal-title":"Sci Rep"},{"issue":"3","key":"10.1016\/j.dld.2025.04.008_bib0035","doi-asserted-by":"crossref","first-page":"730","DOI":"10.1007\/s12072-021-10188-5","article-title":"Prediction of overt hepatic encephalopathy after transjugular intrahepatic portosystemic shunt treatment: a cohort study","volume":"15","author":"Yang","year":"2021","journal-title":"Hepatol Int"},{"issue":"4","key":"10.1016\/j.dld.2025.04.008_bib0036","doi-asserted-by":"crossref","first-page":"596","DOI":"10.1016\/j.jhep.2023.11.033","article-title":"Episodic overt hepatic encephalopathy after transjugular intrahepatic portosystemic shunt does not increase mortality in patients with cirrhosis","volume":"80","author":"Nardelli","year":"2024","journal-title":"J Hepatol"},{"issue":"3","key":"10.1016\/j.dld.2025.04.008_bib0037","doi-asserted-by":"crossref","DOI":"10.1016\/j.clinre.2023.102274","article-title":"Population characteristics, healthcare pathways and outcomes of patients with cirrhosis hospitalized with overt hepatic encephalopathy in France: a study of the French hospital-discharge database","volume":"48","author":"Thabut","year":"2024","journal-title":"Clin Res Hepatol Gastroenterol"},{"issue":"7","key":"10.1016\/j.dld.2025.04.008_bib0038","doi-asserted-by":"crossref","first-page":"1864","DOI":"10.1016\/j.cgh.2022.10.023","article-title":"Role of oral health, frailty, and minimal hepatic encephalopathy in the risk of hospitalization: a prospective multi-center cohort of outpatients with cirrhosis","volume":"21","author":"Bajaj","year":"2023","journal-title":"Clin Gastroenterol Hepatol"},{"issue":"2","key":"10.1016\/j.dld.2025.04.008_bib0039","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1016\/j.jhep.2013.10.004","article-title":"Characteristics, risk factors, and mortality of cirrhotic patients hospitalized for hepatic encephalopathy with and without acute-on-chronic liver failure (ACLF)","volume":"60","author":"Cordoba","year":"2014","journal-title":"J Hepatol"},{"key":"10.1016\/j.dld.2025.04.008_bib0040","doi-asserted-by":"crossref","DOI":"10.3389\/fmed.2023.1184860","article-title":"Hepatic encephalopathy increases the risk for mortality and hospital readmission in decompensated cirrhotic patients: a prospective multicenter study","volume":"10","author":"Riggio","year":"2023","journal-title":"Front Med"},{"issue":"12","key":"10.1016\/j.dld.2025.04.008_bib0041","doi-asserted-by":"crossref","first-page":"1397","DOI":"10.1111\/apt.15749","article-title":"Outcomes after hepatic encephalopathy in population-based cohorts of patients with cirrhosis","volume":"51","author":"Tapper","year":"2020","journal-title":"Aliment Pharmacol Ther"},{"issue":"3","key":"10.1016\/j.dld.2025.04.008_bib0042","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1080\/14737167.2021.1927717","article-title":"Predictors of 30-day readmission and hospitalization costs of patients with hepatic encephalopathy in the US from 2010 to 2014","volume":"22","author":"Chen","year":"2022","journal-title":"Expert Rev Pharmacoecon Outcomes Res"},{"issue":"2","key":"10.1016\/j.dld.2025.04.008_bib0043","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/j.cld.2020.01.006","article-title":"The health care burden of hepatic encephalopathy","volume":"24","author":"Elsaid","year":"2020","journal-title":"Clin Liver Dis"},{"issue":"8","key":"10.1016\/j.dld.2025.04.008_bib0044","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1097\/00005650-198108000-00001","article-title":"The sickness impact profile: development and final revision of a health status measure","volume":"19","author":"Bergner","year":"1981","journal-title":"Med Care"},{"issue":"2","key":"10.1016\/j.dld.2025.04.008_bib0045","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1136\/gut.45.2.295","article-title":"Development of a disease specific questionnaire to measure health related quality of life in patients with chronic liver disease","volume":"45","author":"Younossi","year":"1999","journal-title":"Gut"},{"issue":"10","key":"10.1016\/j.dld.2025.04.008_bib0046","doi-asserted-by":"crossref","first-page":"2827","DOI":"10.1002\/hep4.2030","article-title":"The emotional burden of caregiving for patients with cirrhosis","volume":"6","author":"Saleh","year":"2022","journal-title":"Hepatol Commun"},{"issue":"9","key":"10.1016\/j.dld.2025.04.008_bib0047","doi-asserted-by":"crossref","first-page":"1646","DOI":"10.1038\/ajg.2011.157","article-title":"The multi-dimensional burden of cirrhosis and hepatic encephalopathy on patients and caregivers","volume":"106","author":"Bajaj","year":"2011","journal-title":"Am J Gastroenterol"},{"issue":"5","key":"10.1016\/j.dld.2025.04.008_bib0048","first-page":"385","article-title":"Gender differences in mental health","volume":"48","author":"Afifi","year":"2007","journal-title":"Singapore Med J"},{"issue":"1","key":"10.1016\/j.dld.2025.04.008_bib0049","first-page":"47","article-title":"Gender differences in determinants and consequences of health and illness","volume":"25","author":"Vlassoff","year":"2007","journal-title":"J Health Popul Nutr"},{"issue":"11","key":"10.1016\/j.dld.2025.04.008_bib0050","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0259223","article-title":"Measurement of gender as a social determinant of health in epidemiology-a scoping review","volume":"16","author":"Miani","year":"2021","journal-title":"PLoS One"},{"issue":"12","key":"10.1016\/j.dld.2025.04.008_bib0051","doi-asserted-by":"crossref","first-page":"2965","DOI":"10.1111\/liv.15060","article-title":"The improvement in body composition including subcutaneous and visceral fat reduces ammonia and hepatic encephalopathy after transjugular intrahepatic portosystemic shunt","volume":"41","author":"Gioia","year":"2021","journal-title":"Liver Int"},{"issue":"4","key":"10.1016\/j.dld.2025.04.008_bib0052","doi-asserted-by":"crossref","first-page":"967","DOI":"10.1016\/j.jhep.2023.05.022","article-title":"Development and validation of the AMMON-OHE model to predict risk of overt hepatic encephalopathy occurrence in outpatients with cirrhosis","volume":"79","author":"Ballester","year":"2023","journal-title":"J Hepatol"},{"issue":"1","key":"10.1016\/j.dld.2025.04.008_bib0053","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1016\/j.jhep.2020.06.046","article-title":"Sex is associated with differences in gut microbial composition and function in hepatic encephalopathy","volume":"74","author":"Saboo","year":"2021","journal-title":"J Hepatol"},{"issue":"8","key":"10.1016\/j.dld.2025.04.008_bib0054","doi-asserted-by":"crossref","first-page":"2309","DOI":"10.1007\/s11064-023-03916-w","article-title":"Active clinical trials in hepatic encephalopathy: something old, something new and something borrowed","volume":"48","author":"Balzano","year":"2023","journal-title":"Neurochem Res"},{"issue":"6","key":"10.1016\/j.dld.2025.04.008_bib0055","doi-asserted-by":"crossref","first-page":"2389","DOI":"10.1007\/s10620-023-07935-z","article-title":"Barriers to lactulose adherence in patients with cirrhosis and hepatic encephalopathy","volume":"68","author":"Chow","year":"2023","journal-title":"Dig Dis Sci"},{"issue":"4","key":"10.1016\/j.dld.2025.04.008_bib0056","doi-asserted-by":"crossref","DOI":"10.3390\/biology13040228","article-title":"Age and sex in the development of hepatic encephalopathy: role of alcohol","volume":"13","author":"Tong","year":"2024","journal-title":"Biology"},{"issue":"4","key":"10.1016\/j.dld.2025.04.008_bib0057","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1111\/jnc.15661","article-title":"Sex is associated with differences in oxidative stress and susceptibility to severe hepatic encephalopathy in bile-duct ligated rats","volume":"162","author":"Macedo de Oliveira","year":"2022","journal-title":"J Neurochem"}],"container-title":["Digestive and Liver Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1590865825003226?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1590865825003226?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,7,17]],"date-time":"2025-07-17T12:30:43Z","timestamp":1752755443000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1590865825003226"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7]]},"references-count":57,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2025,7]]}},"alternative-id":["S1590865825003226"],"URL":"https:\/\/doi.org\/10.1016\/j.dld.2025.04.008","relation":{},"ISSN":["1590-8658"],"issn-type":[{"value":"1590-8658","type":"print"}],"subject":[],"published":{"date-parts":[[2025,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Sex differences in hepatic encephalopathy: addressing the knowledge gap","name":"articletitle","label":"Article Title"},{"value":"Digestive and Liver Disease","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.dld.2025.04.008","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Author(s). Published by Elsevier Ltd on behalf of Editrice Gastroenterologica Italiana S.r.l.","name":"copyright","label":"Copyright"}]}}