{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,30]],"date-time":"2026-05-30T01:36:31Z","timestamp":1780104991715,"version":"3.54.0"},"reference-count":37,"publisher":"Elsevier BV","issue":"7","license":[{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,4,17]],"date-time":"2025-04-17T00:00:00Z","timestamp":1744848000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100007052","name":"Universit\u00e0 degli Studi di Verona","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100007052","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004702","name":"Universit\u00e0 degli Studi di Genova","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004702","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100020307","name":"Azienda Ospedaliero-Universitaria Citt\u00e0 della Salute e della Scienza di Torino","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100020307","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008252","name":"Universit\u00e0 degli Studi di Udine","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100008252","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001690","name":"Atsumi International Scholarship Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001690","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100009702","name":"Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100009702","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005743","name":"Universit\u00e0 Cattolica del Sacro Cuore","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005743","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100020412","name":"Humanitas Research Hospital","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100020412","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","dldjournalonline.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Digestive and Liver Disease"],"published-print":{"date-parts":[[2025,7]]},"DOI":"10.1016\/j.dld.2025.04.023","type":"journal-article","created":{"date-parts":[[2025,5,3]],"date-time":"2025-05-03T07:10:21Z","timestamp":1746256221000},"page":"1434-1441","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"title":["Management of ascites in elderly patients with cirrhosis: Results of an Italian survey"],"prefix":"10.1016","volume":"57","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6414-4404","authenticated-orcid":false,"given":"Simone","family":"Di-Cola","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucia","family":"Lapenna","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Margherita","family":"Spigaroli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvia","family":"Nardelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manuela","family":"Merli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"2","key":"10.1016\/j.dld.2025.04.023_bib0001","doi-asserted-by":"crossref","first-page":"1","DOI":"10.12968\/hmed.2019.0377","article-title":"Global ageing: successes, challenges and opportunities","volume":"81","author":"Mitchell","year":"2020","journal-title":"Br J Hosp Med"},{"issue":"6","key":"10.1016\/j.dld.2025.04.023_bib0002","doi-asserted-by":"crossref","first-page":"950","DOI":"10.1111\/acel.12128","article-title":"Liver diseases and aging: friends or foes?","volume":"12","author":"Sheedfar","year":"2013","journal-title":"Aging Cell"},{"issue":"6","key":"10.1016\/j.dld.2025.04.023_bib0003","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1038\/s41575-023-00759-2","article-title":"Global epidemiology of cirrhosis - aetiology, trends and predictions","volume":"20","author":"Huang","year":"2023","journal-title":"Nat Rev Gastroenterol Hepatol"},{"issue":"8","key":"10.1016\/j.dld.2025.04.023_bib0004","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1016\/j.tem.2024.02.007","article-title":"Current status and future trends of the global burden of MASLD","volume":"35","author":"Miao","year":"2024","journal-title":"Trends Endocrinol Metab"},{"issue":"2","key":"10.1016\/j.dld.2025.04.023_bib0005","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1016\/j.jhep.2018.03.024","article-title":"European Association for the Study of the Liver. EASL Clinical Practice Guidelines for the management of patients with decompensated cirrhosis","volume":"69","year":"2018","journal-title":"J Hepatol"},{"issue":"2","key":"10.1016\/j.dld.2025.04.023_bib0006","doi-asserted-by":"crossref","first-page":"1014","DOI":"10.1002\/hep.31884","article-title":"Diagnosis, evaluation, and management of ascites, spontaneous bacterial peritonitis and hepatorenal Syndrome: 2021 practice guidance by the American Association for the Study of Liver Diseases","volume":"74","author":"Biggins","year":"2021","journal-title":"Hepatology"},{"issue":"6","key":"10.1016\/j.dld.2025.04.023_bib0007","doi-asserted-by":"crossref","first-page":"1199","DOI":"10.1016\/j.jhep.2012.07.020","article-title":"Factors related to quality of life in patients with cirrhosis and ascites: relevance of serum sodium concentration and leg edema","volume":"57","author":"Sol\u00e0","year":"2012","journal-title":"J Hepatol"},{"issue":"15","key":"10.1016\/j.dld.2025.04.023_bib0008","doi-asserted-by":"crossref","first-page":"1817","DOI":"10.3748\/wjg.v25.i15.1817","article-title":"Considerations of elderly factors to manage the complication of liver cirrhosis in elderly patients","volume":"25","author":"Kamimura","year":"2019","journal-title":"World J Gastroenterol"},{"issue":"9","key":"10.1016\/j.dld.2025.04.023_bib0009","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1038\/sj.jhh.1001458","article-title":"Diuretic induced hyponatraemia in elderly hypertensive women","volume":"16","author":"Sharabi","year":"2002","journal-title":"J Hum Hypertens"},{"issue":"1","key":"10.1016\/j.dld.2025.04.023_bib0010","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1136\/gutjnl-2011-301255","article-title":"Acute kidney injury in decompensated cirrhosis","volume":"62","author":"Tsien","year":"2013","journal-title":"Gut"},{"issue":"10138","key":"10.1016\/j.dld.2025.04.023_bib0011","doi-asserted-by":"crossref","first-page":"2417","DOI":"10.1016\/S0140-6736(18)30840-7","article-title":"Long-term albumin administration in decompensated cirrhosis (ANSWER): an open-label randomised trial","volume":"391","author":"Caraceni","year":"2018","journal-title":"Lancet"},{"issue":"1","key":"10.1016\/j.dld.2025.04.023_bib0012","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1007\/s10238-024-01315-1","article-title":"Role of albumin infusion in cirrhosis-associated complications","volume":"24","author":"Heybe","year":"2024","journal-title":"Clin Exp Med"},{"issue":"7","key":"10.1016\/j.dld.2025.04.023_bib0013","doi-asserted-by":"crossref","first-page":"1173","DOI":"10.1136\/gutjnl-2019-320221","article-title":"Transjugular intrahepatic portosystemic stent-shunt in the management of portal hypertension","volume":"69","author":"Tripathi","year":"2020","journal-title":"Gut"},{"key":"10.1016\/j.dld.2025.04.023_bib0014","doi-asserted-by":"crossref","first-page":"1","DOI":"10.4061\/2011\/121862","article-title":"Indications and contraindications for liver transplantation","volume":"2011","author":"Varma","year":"2011","journal-title":"Int J Hepatol"},{"issue":"8","key":"10.1016\/j.dld.2025.04.023_bib0015","doi-asserted-by":"crossref","first-page":"957","DOI":"10.1002\/lt.20155","article-title":"Older age and liver transplantation: a review","volume":"10","author":"Keswani","year":"2004","journal-title":"Liver Transplant"},{"issue":"4","key":"10.1016\/j.dld.2025.04.023_bib0016","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1002\/lt.23385","article-title":"Liver transplantation in septuagenarians receiving model for end-stage liver disease exception points for hepatocellular carcinoma: the national experience","volume":"18","author":"Schwartz","year":"2012","journal-title":"Liver Transplant"},{"issue":"3","key":"10.1016\/j.dld.2025.04.023_bib0017","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1016\/j.jhep.2012.04.015","article-title":"Evolution of indications and results of liver transplantation in Europe. a report from the european liver transplant registry (ELTR)","volume":"57","author":"Adam","year":"2012","journal-title":"J Hepatol"},{"issue":"8","key":"10.1016\/j.dld.2025.04.023_bib0018","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1001\/archsurg.142.8.775","article-title":"Outcome of liver transplantation in septuagenarians","volume":"142","author":"Lipshutz","year":"2007","journal-title":"Arch Surg"},{"issue":"3","key":"10.1016\/j.dld.2025.04.023_bib0019","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1016\/j.jhep.2010.05.004","article-title":"European Association for the Study of the Liver. EASL clinical practice guidelines on the management of ascites, spontaneous bacterial peritonitis, and hepatorenal syndrome in cirrhosis","volume":"53","year":"2010","journal-title":"J Hepatol"},{"issue":"18","key":"10.1016\/j.dld.2025.04.023_bib0020","doi-asserted-by":"crossref","first-page":"1589","DOI":"10.1001\/jama.2023.5997","article-title":"Diagnosis and management of cirrhosis and its complications","volume":"329","author":"Tapper","year":"2023","journal-title":"JAMA"},{"issue":"2","key":"10.1016\/j.dld.2025.04.023_bib0021","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1016\/j.jhep.2013.03.010","article-title":"How to improve care in outpatients with cirrhosis and ascites: a new model of care coordination by consultant hepatologists","volume":"59","author":"Morando","year":"2013","journal-title":"J Hepatol"},{"issue":"1","key":"10.1016\/j.dld.2025.04.023_bib0022","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1002\/hep.24616","article-title":"Burden of cirrhosis on older Americans and their families","volume":"55","author":"Rakoski","year":"2012","journal-title":"Hepatology"},{"issue":"1","key":"10.1016\/j.dld.2025.04.023_bib0023","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1136\/gutjnl-2020-321790","article-title":"Guidelines on the management of ascites in cirrhosis","volume":"70","author":"Aithal","year":"2021","journal-title":"Gut"},{"issue":"1","key":"10.1016\/j.dld.2025.04.023_bib0024","first-page":"1","article-title":"The crucial role of risk factors when dealing with hepatic encephalopathy","volume":"40","author":"Lapenna","year":"2025","journal-title":"Metab Brain Dis"},{"issue":"6","key":"10.1016\/j.dld.2025.04.023_bib0025","doi-asserted-by":"crossref","first-page":"1127","DOI":"10.1136\/gutjnl-2019-318843","article-title":"Albumin in decompensated cirrhosis: new concepts and perspectives","volume":"69","author":"Bernardi","year":"2020","journal-title":"Gut"},{"issue":"33","key":"10.1016\/j.dld.2025.04.023_bib0026","doi-asserted-by":"crossref","first-page":"4773","DOI":"10.3748\/wjg.v28.i33.4773","article-title":"Albumin administration in patients with cirrhosis: current role and novel perspectives","volume":"28","author":"de Mattos","year":"2022","journal-title":"World J Gastroenterol"},{"issue":"6","key":"10.1016\/j.dld.2025.04.023_bib0027","doi-asserted-by":"crossref","first-page":"1306","DOI":"10.1016\/j.jhep.2022.03.005","article-title":"Long-term albumin treatment in patients with cirrhosis and ascites","volume":"76","author":"Caraceni","year":"2022","journal-title":"J Hepatol"},{"issue":"7446","key":"10.1016\/j.dld.2025.04.023_bib0028","doi-asserted-by":"crossref","first-page":"1049","DOI":"10.1016\/S0140-6736(66)91005-1","article-title":"Complications of diuretic therapy in hepatic cirrhosis","volume":"287","author":"Sherlock","year":"1966","journal-title":"Lancet"},{"issue":"12","key":"10.1016\/j.dld.2025.04.023_bib0029","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhepr.2024.101221","article-title":"Real-world experience with long-term albumin in patients with cirrhosis and ascites","volume":"6","author":"Pompili","year":"2024","journal-title":"JHEP Reports"},{"issue":"5","key":"10.1016\/j.dld.2025.04.023_bib0030","article-title":"Infection prevention and control programme and COVID-19 measures: effects on hospital-acquired infections in patients with cirrhosis","volume":"5","author":"Di Cola","year":"2023","journal-title":"JHEP reports Innov Hepatol"},{"issue":"4","key":"10.1016\/j.dld.2025.04.023_bib0031","first-page":"385","article-title":"Large volume paracentesis in patients with liver cirrhosis temporarily diminishes blood cell count","volume":"48","author":"Haghighat","year":"2023","journal-title":"Iran J Med Sci"},{"key":"10.1016\/j.dld.2025.04.023_bib0032","doi-asserted-by":"crossref","unstructured":"Stockhoff L., Schultalbers M., Tergast T.L., et al. Safety and feasibility of transjugular intrahepatic portosystemic shunt in elderly patients with liver cirrhosis and refractory ascites. Strnad P, editor PLoS One. 2020;15(6):e0235199. doi:10.1371\/journal.pone.0235199","DOI":"10.1371\/journal.pone.0235199"},{"issue":"2","key":"10.1016\/j.dld.2025.04.023_bib0033","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1002\/hep.32704","article-title":"Mortality after transjugular intrahepatic portosystemic shunt in older adult patients with cirrhosis: a validated prediction model","volume":"77","author":"Vizzutti","year":"2023","journal-title":"Hepatology"},{"issue":"6","key":"10.1016\/j.dld.2025.04.023_bib0034","doi-asserted-by":"crossref","first-page":"1362","DOI":"10.1016\/j.jhep.2021.01.023","article-title":"Refining prediction of survival after TIPS with the novel Freiburg index of post-TIPS survival","volume":"74","author":"Bettinger","year":"2021","journal-title":"J Hepatol"},{"issue":"4","key":"10.1016\/j.dld.2025.04.023_bib0035","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1016\/j.jhep.2018.12.009","article-title":"Age and liver transplantation","volume":"70","author":"Durand","year":"2019","journal-title":"J Hepatol"},{"issue":"5","key":"10.1016\/j.dld.2025.04.023_bib0036","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1111\/apt.15122","article-title":"Editorial: quality of life and mortality in cirrhosis and ascites","volume":"49","author":"O\u2019Carroll","year":"2019","journal-title":"Aliment Pharmacol Ther"},{"key":"10.1016\/j.dld.2025.04.023_bib0037","doi-asserted-by":"crossref","DOI":"10.1136\/spcare-2024-004839","article-title":"Health-related quality of life and frailty in liver cirrhosis","author":"Hui","year":"2024","journal-title":"BMJ Support Palliat Care"}],"container-title":["Digestive and Liver Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1590865825007376?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1590865825007376?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T22:28:14Z","timestamp":1762554494000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1590865825007376"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7]]},"references-count":37,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2025,7]]}},"alternative-id":["S1590865825007376"],"URL":"https:\/\/doi.org\/10.1016\/j.dld.2025.04.023","relation":{},"ISSN":["1590-8658"],"issn-type":[{"value":"1590-8658","type":"print"}],"subject":[],"published":{"date-parts":[[2025,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Management of ascites in elderly patients with cirrhosis: Results of an Italian survey","name":"articletitle","label":"Article Title"},{"value":"Digestive and Liver Disease","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.dld.2025.04.023","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Author(s). Published by Elsevier Ltd on behalf of Editrice Gastroenterologica Italiana S.r.l.","name":"copyright","label":"Copyright"}]}}