{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T22:26:11Z","timestamp":1778624771799,"version":"3.51.4"},"reference-count":31,"publisher":"Elsevier BV","issue":"9","license":[{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,6,9]],"date-time":"2025-06-09T00:00:00Z","timestamp":1749427200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100012157","name":"Shanghai Key Discipline Construction Project","doi-asserted-by":"publisher","award":["ZK2019B24"],"award-info":[{"award-number":["ZK2019B24"]}],"id":[{"id":"10.13039\/501100012157","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100017950","name":"Shanghai Municipal Health Commission","doi-asserted-by":"publisher","award":["GWVI-11.1-09"],"award-info":[{"award-number":["GWVI-11.1-09"]}],"id":[{"id":"10.13039\/100017950","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010167","name":"Shanghai Shen Kang Hospital Development Center","doi-asserted-by":"publisher","award":["SHDC12019116"],"award-info":[{"award-number":["SHDC12019116"]}],"id":[{"id":"10.13039\/501100010167","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81871640"],"award-info":[{"award-number":["81871640"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82372237"],"award-info":[{"award-number":["82372237"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82172255"],"award-info":[{"award-number":["82172255"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003399","name":"Shanghai Municipality Science and Technology Commission","doi-asserted-by":"publisher","award":["ZD2021CY001"],"award-info":[{"award-number":["ZD2021CY001"]}],"id":[{"id":"10.13039\/501100003399","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010120","name":"Huashan Hospital Fudan University","doi-asserted-by":"publisher","award":["YN012"],"award-info":[{"award-number":["YN012"]}],"id":[{"id":"10.13039\/501100010120","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003347","name":"Fudan University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003347","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005198","name":"China Foundation for Hepatitis Prevention and Control","doi-asserted-by":"publisher","award":["Mx202412"],"award-info":[{"award-number":["Mx202412"]}],"id":[{"id":"10.13039\/501100005198","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Shanghai key clinical specialty construction program"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","dldjournalonline.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Digestive and Liver Disease"],"published-print":{"date-parts":[[2025,9]]},"DOI":"10.1016\/j.dld.2025.05.028","type":"journal-article","created":{"date-parts":[[2025,6,19]],"date-time":"2025-06-19T07:20:54Z","timestamp":1750317654000},"page":"1794-1801","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"title":["Unveiling the clinical spectrum of Porto-Sinusoidal Vascular Disorder (PSVD) with chronic HBV infection: insights from a retrospective Chinese cohort"],"prefix":"10.1016","volume":"57","author":[{"given":"Jinyu","family":"Wang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tiantian","family":"Hu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiangyu","family":"Chi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hao","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuqi","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wentao","family":"Xie","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiajia","family":"Han","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qian","family":"Qiu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kangkang","family":"Yu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chong","family":"Huang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jubo","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qingchun","family":"Fu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qi","family":"Miao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zunguo","family":"Du","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haoxiang","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiming","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.dld.2025.05.028_bib0001","doi-asserted-by":"crossref","first-page":"1124","DOI":"10.1016\/j.jhep.2022.05.033","article-title":"Porto-sinusoidal vascular disorder","volume":"77","author":"De Gottardi","year":"2022","journal-title":"J Hepatol"},{"key":"10.1016\/j.dld.2025.05.028_bib0002","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1016\/S2468-1253(19)30047-0","article-title":"Porto-sinusoidal vascular disease: proposal and description of a novel entity","volume":"4","author":"De Gottardi","year":"2019","journal-title":"Lancet Gastroenterol Hepatol"},{"key":"10.1016\/j.dld.2025.05.028_bib0003","doi-asserted-by":"crossref","first-page":"924","DOI":"10.1016\/j.jhep.2021.05.014","article-title":"Co-expression gene network analysis reveals novel regulatory pathways involved in porto-sinusoidal vascular disease","volume":"75","author":"Hernandez-Gea","year":"2021","journal-title":"J Hepatol"},{"key":"10.1016\/j.dld.2025.05.028_bib0004","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1016\/j.jhep.2017.03.021","article-title":"Electronic address eee, European Association for the Study of the L. EASL 2017 clinical practice guidelines on the management of hepatitis B virus infection","volume":"67","year":"2017","journal-title":"J Hepatol"},{"key":"10.1016\/j.dld.2025.05.028_bib0005","article-title":"Porto-sinusoidal vascular disorder in chronic HBV: a significant coexistence not to be overlooked","volume":"6","author":"Olivas","year":"2024","journal-title":"JHEP Rep"},{"key":"10.1016\/j.dld.2025.05.028_bib0006","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1016\/S2468-1253(18)30056-6","article-title":"Global prevalence, treatment, and prevention of hepatitis B virus infection in 2016: a modelling study","volume":"3","author":"Polaris Observatory","year":"2018","journal-title":"Lancet Gastroenterol Hepatol"},{"key":"10.1016\/j.dld.2025.05.028_bib0007","doi-asserted-by":"crossref","DOI":"10.1016\/j.bcp.2021.114592","article-title":"UGT1A1 dysfunction increases liver burden and aggravates hepatocyte damage caused by long-term bilirubin metabolism disorder","volume":"190","author":"Liu","year":"2021","journal-title":"Biochem Pharmacol"},{"key":"10.1016\/j.dld.2025.05.028_bib0008","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-017-11626-x","article-title":"An expanded role for heterozygous mutations of ABCB4, ABCB11, ATP8B1, ABCC2 and TJP2 in intrahepatic cholestasis of pregnancy","volume":"7","author":"Dixon","year":"2017","journal-title":"Sci Rep"},{"key":"10.1016\/j.dld.2025.05.028_bib0009","doi-asserted-by":"crossref","first-page":"666","DOI":"10.1002\/hep.29100","article-title":"The ABCB4 p.T175A variant as potential modulator of hepatic fibrosis in patients with chronic liver diseases: looking beyond the cholestatic realm","volume":"66","author":"Krawczyk","year":"2017","journal-title":"Hepatology"},{"key":"10.1016\/j.dld.2025.05.028_bib0010","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.thromres.2020.11.027","article-title":"Prevalence of definite antiphospholipid syndrome in carriers of the JAK2(V617F) mutation","volume":"198","author":"Janjetovic","year":"2021","journal-title":"Thromb Res"},{"key":"10.1016\/j.dld.2025.05.028_bib0011","doi-asserted-by":"crossref","first-page":"1891","DOI":"10.1007\/s00261-020-02831-w","article-title":"Porto-sinusoidal vascular disease with portal hypertension versus liver cirrhosis: differences in imaging features on CT and hepatobiliary contrast-enhanced MRI","volume":"46","author":"Kang","year":"2021","journal-title":"Abdom Radiol (NY)"},{"key":"10.1016\/j.dld.2025.05.028_bib0012","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1007\/s11239-021-02525-0","article-title":"The first report of a JAK2 V617F-positive myeloproliferative neoplasm with initial manifestation as a rare pampiniform venous plexus thrombosis and review of the literature","volume":"53","author":"Jacobs","year":"2022","journal-title":"J Thromb Thrombolysis"},{"key":"10.1016\/j.dld.2025.05.028_bib0013","doi-asserted-by":"crossref","DOI":"10.3389\/frtra.2023.1221765","article-title":"Al-Adra DP. Nodular regenerative hyperplasia and liver transplantation: a systematic review","volume":"2","author":"Biesterveld","year":"2023","journal-title":"Front Transplant"},{"key":"10.1016\/j.dld.2025.05.028_bib0014","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1078\/0171-2985-00209","article-title":"Nodular regenerative hyperplasia (NRH) of the liver\u2013a manifestation of 'organ-specific antiphospholipid syndrome'?","volume":"207","author":"Klein","year":"2003","journal-title":"Immunobiology"},{"key":"10.1016\/j.dld.2025.05.028_bib0015","doi-asserted-by":"crossref","first-page":"1770","DOI":"10.1111\/liv.13718","article-title":"Focus on histological abnormalities of intrahepatic vasculature in chronic viral hepatitis","volume":"38","author":"Guido","year":"2018","journal-title":"Liver Int"},{"key":"10.1016\/j.dld.2025.05.028_bib0016","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1016\/j.jhep.2021.12.022","article-title":"Baveno VII - renewing consensus in portal hypertension","volume":"76","author":"de Franchis","year":"2022","journal-title":"J Hepatol"},{"key":"10.1016\/j.dld.2025.05.028_bib0017","doi-asserted-by":"crossref","first-page":"49","DOI":"10.14740\/gr1376","article-title":"Idiopathic non-cirrhotic portal hypertension and porto-sinusoidal vascular disease: review of current data","volume":"14","author":"Kmeid","year":"2021","journal-title":"Gastroenterol Res"},{"key":"10.1016\/j.dld.2025.05.028_bib0018","doi-asserted-by":"crossref","first-page":"2220","DOI":"10.1111\/liv.15676","article-title":"Hepatic recompensation according to Baveno VII criteria is linked to a significant survival benefit in decompensated alcohol-related cirrhosis","volume":"43","author":"Hofer","year":"2023","journal-title":"Liver Int"},{"key":"10.1016\/j.dld.2025.05.028_bib0019","doi-asserted-by":"crossref","first-page":"1293","DOI":"10.1002\/hep.28992","article-title":"Effects of an intensive lifestyle intervention program on portal hypertension in patients with cirrhosis and obesity: the SportDiet study","volume":"65","author":"Berzigotti","year":"2017","journal-title":"Hepatology"},{"key":"10.1016\/j.dld.2025.05.028_bib0020","doi-asserted-by":"crossref","DOI":"10.1016\/j.nut.2020.111095","article-title":"Body mass index changes after transjugular intrahepatic portosystemic shunt in individuals with cirrhosis","volume":"84","author":"Pang","year":"2021","journal-title":"Nutrition"},{"key":"10.1016\/j.dld.2025.05.028_bib0021","doi-asserted-by":"crossref","first-page":"1417","DOI":"10.1111\/jgh.14552","article-title":"Clinical features of idiopathic portal hypertension in China: a retrospective study of 338 patients and literature review","volume":"34","author":"Sun","year":"2019","journal-title":"J Gastroenterol Hepatol"},{"key":"10.1016\/j.dld.2025.05.028_bib0022","doi-asserted-by":"crossref","first-page":"e132","DOI":"10.1097\/MPG.0000000000003445","article-title":"Porto-sinusoidal vascular disease: a pediatric study of 30 patients","volume":"74","author":"Girard","year":"2022","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"10.1016\/j.dld.2025.05.028_bib0023","doi-asserted-by":"crossref","first-page":"2329","DOI":"10.1111\/liv.16002","article-title":"Clinical characteristics and natural history of porto-sinusoidal vascular disease: a cohort study of 234 patients in China","volume":"44","author":"Zhang","year":"2024","journal-title":"Liver Int"},{"key":"10.1016\/j.dld.2025.05.028_bib0024","doi-asserted-by":"crossref","first-page":"1523","DOI":"10.1111\/liv.15603","article-title":"Paediatric porto-sinusoidal vascular disease: two different clinical phenotypes with subtle histological differences","volume":"43","author":"Di Giorgio","year":"2023","journal-title":"Liver Int"},{"key":"10.1016\/j.dld.2025.05.028_bib0025","doi-asserted-by":"crossref","first-page":"904","DOI":"10.1002\/jgh3.12840","article-title":"Obliterative portal venopathy: a neglected and probably misdiagnosed disease with peculiar etiology in South America","volume":"6","author":"Nunes","year":"2022","journal-title":"JGH Open"},{"key":"10.1016\/j.dld.2025.05.028_bib0026","article-title":"Link between persistent, unexplained gamma-glutamyltransferase elevation and porto-sinusoidal vascular disorder","volume":"6","author":"Pugliese","year":"2024","journal-title":"JHEP Rep"},{"key":"10.1016\/j.dld.2025.05.028_bib0027","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1111\/liv.15099","article-title":"Gamma-glutamyl Transferase (gamma-GT) - an old dog with new tricks?","volume":"42","author":"Brennan","year":"2022","journal-title":"Liver Int"},{"key":"10.1016\/j.dld.2025.05.028_bib0028","first-page":"140","article-title":"Nitro-oxidative stress, VEGF and MMP-9 in patients with cirrhotic and non-cirrhotic portal hypertension","volume":"88","author":"Muti","year":"2015","journal-title":"Clujul Med"},{"key":"10.1016\/j.dld.2025.05.028_bib0029","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1097\/MOG.0000000000001106","article-title":"Noncirrhotic portal hypertension: current trends and future directions","volume":"41","author":"Meena","year":"2025","journal-title":"Curr Opin Gastroenterol"},{"key":"10.1016\/j.dld.2025.05.028_bib0030","doi-asserted-by":"crossref","DOI":"10.1111\/liv.70096","article-title":"Prognostic role of endoscopic ultrasound guided direct portal pressure gradient measurement in porto-sinusoidal vascular disorder","volume":"45","author":"Santopaolo","year":"2025","journal-title":"Liver Int"},{"key":"10.1016\/j.dld.2025.05.028_bib0031","article-title":"Genetic predisposition to porto-sinusoidal vascular disorder","author":"Ciriaci","year":"2024","journal-title":"Hepatology"}],"container-title":["Digestive and Liver Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1590865825008011?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1590865825008011?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T21:34:30Z","timestamp":1778621670000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1590865825008011"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9]]},"references-count":31,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2025,9]]}},"alternative-id":["S1590865825008011"],"URL":"https:\/\/doi.org\/10.1016\/j.dld.2025.05.028","relation":{},"ISSN":["1590-8658"],"issn-type":[{"value":"1590-8658","type":"print"}],"subject":[],"published":{"date-parts":[[2025,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Unveiling the clinical spectrum of Porto-Sinusoidal Vascular Disorder (PSVD) with chronic HBV infection: insights from a retrospective Chinese cohort","name":"articletitle","label":"Article Title"},{"value":"Digestive and Liver Disease","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.dld.2025.05.028","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier Ltd on behalf of Editrice Gastroenterologica Italiana S.r.l.","name":"copyright","label":"Copyright"}]}}