{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T21:56:06Z","timestamp":1779918966669,"version":"3.53.1"},"reference-count":33,"publisher":"Elsevier BV","issue":"12","license":[{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2023YFC2507500"],"award-info":[{"award-number":["2023YFC2507500"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100018617","name":"Liaoning Revitalization Talents Program","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100018617","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","dldjournalonline.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Digestive and Liver Disease"],"published-print":{"date-parts":[[2025,12]]},"DOI":"10.1016\/j.dld.2025.09.019","type":"journal-article","created":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T07:47:44Z","timestamp":1759996064000},"page":"2399-2409","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"title":["hs-cTnT and NT-ProBNP, rather than unspecified coronary artery disease, may be associated with further decompensation and death in liver cirrhosis"],"prefix":"10.1016","volume":"57","author":[{"given":"Liyan","family":"Dong","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yao","family":"Xiao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yibing","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yong","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0021-823X","authenticated-orcid":false,"given":"Xingshun","family":"Qi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huishan","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.dld.2025.09.019_bib0001","first-page":"e2","article-title":"Heart disease and stroke statistics\u20132012 update: a report from the American Heart Association","volume":"125","author":"Roger","year":"2012","journal-title":"Circulation"},{"key":"10.1016\/j.dld.2025.09.019_bib0002","doi-asserted-by":"crossref","first-page":"e347","DOI":"10.1161\/CIR.0000000000001209","article-title":"2024 Heart disease and stroke statistics: a report of US and global data from the American Heart Association","volume":"149","author":"Martin","year":"2024","journal-title":"Circulation"},{"key":"10.1016\/j.dld.2025.09.019_bib0003","doi-asserted-by":"crossref","first-page":"1359","DOI":"10.1016\/S0140-6736(21)01374-X","article-title":"Liver cirrhosis","volume":"398","author":"Gines","year":"2021","journal-title":"Lancet"},{"key":"10.1016\/j.dld.2025.09.019_bib0004","doi-asserted-by":"crossref","first-page":"e19","DOI":"10.1111\/liv.12428","article-title":"Cardiac and proinflammatory markers predict prognosis in cirrhosis","volume":"34","author":"Wiese","year":"2014","journal-title":"Liver Int"},{"key":"10.1016\/j.dld.2025.09.019_bib0005","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1161\/CIRCULATIONAHA.107.699579","article-title":"General cardiovascular risk profile for use in primary care: the Framingham heart study","volume":"117","author":"D\u2019Agostino","year":"2008","journal-title":"Circulation"},{"key":"10.1016\/j.dld.2025.09.019_bib0006","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1016\/0002-8703(60)90192-7","article-title":"The low incidence of myocardial infarction in patients with portal cirrhosis of the liver: a review of 639 cases of cirrhosis of the liver from 17,731 autopsies","volume":"60","author":"Howell","year":"1960","journal-title":"Am Heart J"},{"key":"10.1016\/j.dld.2025.09.019_bib0007","doi-asserted-by":"crossref","first-page":"1036","DOI":"10.3390\/life12071036","article-title":"Ischemic heart disease and liver cirrhosis: adding insult to injury","volume":"12","author":"Girleanu","year":"2022","journal-title":"Life"},{"key":"10.1016\/j.dld.2025.09.019_bib0008","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1111\/j.1478-3231.2005.01002.x","article-title":"Reduced prevalence of ischemic events and abnormal supraortic flow patterns in patients with liver cirrhosis","volume":"25","author":"Berzigotti","year":"2005","journal-title":"Liver Int"},{"key":"10.1016\/j.dld.2025.09.019_bib0009","doi-asserted-by":"crossref","first-page":"3547","DOI":"10.3748\/wjg.v24.i31.3547","article-title":"Favorable clinical outcome of nonalcoholic liver cirrhosis patients with coronary artery disease: a population-based study","volume":"24","author":"Tsai","year":"2018","journal-title":"World J Gastroenterol"},{"key":"10.1016\/j.dld.2025.09.019_bib0010","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/j.atherosclerosis.2018.01.047","article-title":"Risk of acute coronary syndrome and peripheral arterial disease in chronic liver disease and cirrhosis: a nationwide population-based study","volume":"270","author":"Lin","year":"2018","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.dld.2025.09.019_bib0011","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1007\/s10620-009-0738-z","article-title":"Coronary artery disease in patients with liver cirrhosis","volume":"55","author":"Kalaitzakis","year":"2010","journal-title":"Dig Dis Sci"},{"key":"10.1016\/j.dld.2025.09.019_bib0012","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1136\/gut.2009.180570","article-title":"Low cardiac output predicts development of hepatorenal syndrome and survival in patients with cirrhosis and ascites","volume":"59","author":"Krag","year":"2010","journal-title":"Gut"},{"key":"10.1016\/j.dld.2025.09.019_bib0013","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1016\/j.jacc.2008.04.033","article-title":"Minimally elevated cardiac troponin T and elevated N-terminal pro-B-type natriuretic peptide predict mortality in older adults: results from the Rancho Bernardo Study","volume":"52","author":"Daniels","year":"2008","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.dld.2025.09.019_bib0014","doi-asserted-by":"crossref","first-page":"1071","DOI":"10.1016\/j.jacc.2010.06.016","article-title":"Troponin elevation in heart failure prevalence, mechanisms, and clinical implications","volume":"56","author":"Kociol","year":"2010","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.dld.2025.09.019_bib0015","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/j.amjms.2017.04.005","article-title":"Pro-brain natriuretic peptide and troponin t-hypersensitivity levels correlate with the severity of liver dysfunction in liver cirrhosis","volume":"354","author":"Zhao","year":"2017","journal-title":"Am J Med Sci"},{"key":"10.1016\/j.dld.2025.09.019_bib0016","doi-asserted-by":"crossref","first-page":"362","DOI":"10.3325\/cmj.2023.64.362","article-title":"Markers of cardiac injury in patients with liver cirrhosis","volume":"64","author":"Simic","year":"2023","journal-title":"Croat Med J"},{"key":"10.1016\/j.dld.2025.09.019_bib0017","first-page":"308","article-title":"Associations of gallbladder and gallstone parameters with clinical outcomes in patients with cirrhosis","volume":"12","author":"Ding","year":"2024","journal-title":"J Transl Int Med"},{"key":"10.1016\/j.dld.2025.09.019_bib0018","doi-asserted-by":"crossref","first-page":"746","DOI":"10.1016\/j.ijcard.2016.06.337","article-title":"The risk of coronary artery disease and cerebrovascular disease in patients with hepatitis C: a systematic review and meta-analysis","volume":"221","author":"Ambrosino","year":"2016","journal-title":"Int J Cardiol"},{"key":"10.1016\/j.dld.2025.09.019_bib0019","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1016\/j.jhep.2021.12.022","article-title":"Baveno VII - renewing consensus in portal hypertension","volume":"76","author":"de Franchis","year":"2022","journal-title":"J Hepatol"},{"key":"10.1016\/j.dld.2025.09.019_bib0020","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1007\/s12072-014-9531-y","article-title":"Cirrhotic cardiomyopathy: review of pathophysiology and treatment","volume":"8","author":"Chayanupatkul","year":"2014","journal-title":"Hepatol Int"},{"key":"10.1016\/j.dld.2025.09.019_bib0021","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1002\/hep.30875","article-title":"Redefining cirrhotic cardiomyopathy for the modern era","volume":"71","author":"Izzy","year":"2020","journal-title":"Hepatology"},{"key":"10.1016\/j.dld.2025.09.019_bib0022","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1016\/j.cld.2021.01.012","article-title":"Current concepts of cirrhotic cardiomyopathy","volume":"25","author":"Izzy","year":"2021","journal-title":"Clin Liver Dis"},{"key":"10.1016\/j.dld.2025.09.019_bib0023","doi-asserted-by":"crossref","first-page":"S44","DOI":"10.1002\/lt.500060510","article-title":"Cirrhotic cardiomyopathy and liver transplantation","volume":"6","author":"Myers","year":"2000","journal-title":"Liver Transpl"},{"key":"10.1016\/j.dld.2025.09.019_bib0024","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1080\/03007995.2024.2319821","article-title":"Association of echocardiography-related parameters with the prognosis of decompensated cirrhosis: a retrospective cohort study","volume":"40","author":"Wang","year":"2024","journal-title":"Curr Med Res Opin"},{"key":"10.1016\/j.dld.2025.09.019_bib0025","doi-asserted-by":"crossref","first-page":"567","DOI":"10.3390\/cells9030567","article-title":"Relationship between heart disease and liver disease: a two-way street","volume":"9","author":"El Hadi","year":"2020","journal-title":"Cells"},{"key":"10.1016\/j.dld.2025.09.019_bib0026","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1136\/gut.2006.112177","article-title":"Cardiovascular complications of cirrhosis","volume":"57","author":"M\u00f8ller","year":"2008","journal-title":"Gut"},{"key":"10.1016\/j.dld.2025.09.019_bib0027","doi-asserted-by":"crossref","first-page":"6791","DOI":"10.1038\/s41598-020-63744-8","article-title":"The liver and kidneys mediate clearance of cardiac troponin in the rat","volume":"10","author":"Muslimovic","year":"2020","journal-title":"Sci Rep"},{"key":"10.1016\/j.dld.2025.09.019_bib0028","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1007\/s00380-021-01890-3","article-title":"Accuracy of high-sensitive troponin depending on renal function for clinical outcome prediction in patients with acute heart failure","volume":"37","author":"Ledwoch","year":"2022","journal-title":"Heart Vessels"},{"key":"10.1016\/j.dld.2025.09.019_bib0029","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1161\/01.CIR.0000109483.45211.8F","article-title":"Impaired renal clearance explains elevated troponin T fragments in hemodialysis patients","volume":"109","author":"Diris","year":"2004","journal-title":"Circulation"},{"key":"10.1016\/j.dld.2025.09.019_bib0030","doi-asserted-by":"crossref","DOI":"10.1155\/2020\/4019289","article-title":"Correlation of serum cardiac markers with acute decompensating events in liver cirrhosis","volume":"2020","author":"Li","year":"2020","journal-title":"Gastroenterol Res Pract"},{"key":"10.1016\/j.dld.2025.09.019_bib0031","doi-asserted-by":"crossref","DOI":"10.1111\/eci.13205","article-title":"Time-dependent incidence and risk for myocardial infarction in patients with alcoholic cirrhosis","volume":"50","author":"Deleuran","year":"2020","journal-title":"Eur J Clin Invest"},{"key":"10.1016\/j.dld.2025.09.019_bib0032","doi-asserted-by":"crossref","first-page":"1353","DOI":"10.1161\/CIRCULATIONAHA.114.009278","article-title":"Prevalence and prediction of coronary artery disease in patients with liver cirrhosis: a registry-based matched case-control study","volume":"130","author":"An","year":"2014","journal-title":"Circulation"},{"key":"10.1016\/j.dld.2025.09.019_bib0033","doi-asserted-by":"crossref","first-page":"1739","DOI":"10.1093\/rheumatology\/kead522","article-title":"N-terminal pro-brain natriuretic peptide is a biomarker for cardiovascular damage in systemic lupus erythematous: a cross-sectional study","volume":"63","author":"Sacre","year":"2024","journal-title":"Rheumatology"}],"container-title":["Digestive and Liver Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1590865825011223?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1590865825011223?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,12,19]],"date-time":"2025-12-19T14:25:04Z","timestamp":1766154304000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1590865825011223"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12]]},"references-count":33,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2025,12]]}},"alternative-id":["S1590865825011223"],"URL":"https:\/\/doi.org\/10.1016\/j.dld.2025.09.019","relation":{},"ISSN":["1590-8658"],"issn-type":[{"value":"1590-8658","type":"print"}],"subject":[],"published":{"date-parts":[[2025,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"hs-cTnT and NT-ProBNP, rather than unspecified coronary artery disease, may be associated with further decompensation and death in liver cirrhosis","name":"articletitle","label":"Article Title"},{"value":"Digestive and Liver Disease","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.dld.2025.09.019","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Editrice Gastroenterologica Italiana S.r.l. Published by Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}