{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,18]],"date-time":"2026-07-18T09:25:04Z","timestamp":1784366704562,"version":"3.55.0"},"reference-count":10,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","dldjournalonline.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Digestive and Liver Disease"],"published-print":{"date-parts":[[2026,1]]},"DOI":"10.1016\/j.dld.2025.10.024","type":"journal-article","created":{"date-parts":[[2025,11,19]],"date-time":"2025-11-19T02:27:25Z","timestamp":1763519245000},"page":"152-154","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"title":["24-hour colonic manometry can reveal exaggerated rectosigmoid junction (sphincter of O\u2019Beirne) activity in severely constipated patients"],"prefix":"10.1016","volume":"58","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0237-1812","authenticated-orcid":false,"given":"Gabrio","family":"Bassotti","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elisabetta","family":"Antonelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara","family":"Bologna","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ji-Hong","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8016-1055","authenticated-orcid":false,"given":"Jan D.","family":"Huizinga","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.dld.2025.10.024_bib0001","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1186\/s12876-016-0556-7","article-title":"Chronic constipation diagnosis and treatment evaluation: the \"CHRO.CO.DI.T.E.\" study","volume":"17","author":"Bellini","year":"2017","journal-title":"BMC Gastroenterol"},{"key":"10.1016\/j.dld.2025.10.024_bib0002","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1038\/nrgastro.2018.7","article-title":"Expert consensus document: advances in the diagnosis and classification of gastric and intestinal motility disorders","volume":"15","author":"Keller","year":"2018","journal-title":"Nat Rev Gastroenterol Hepatol"},{"key":"10.1016\/j.dld.2025.10.024_bib0003","first-page":"G660","article-title":"Manometric investigation of high-amplitude propagated contractile activity of the human colon","volume":"255","author":"Bassotti","year":"1988","journal-title":"Am J Physiol"},{"key":"10.1016\/j.dld.2025.10.024_bib0004","doi-asserted-by":"crossref","first-page":"3529","DOI":"10.1007\/s10620-020-06723-3","article-title":"The Sphincter of O'Beirne-part 2: report of a case of chronic constipation with autonomous dyssynergia","volume":"66","author":"Chen","year":"2021","journal-title":"Dig Dis Sci"},{"key":"10.1016\/j.dld.2025.10.024_bib0005","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1016\/S0016-5085(76)80546-X","article-title":"Characterization of a hyperactive segment at the rectosigmoid junction","volume":"71","author":"Chowdhury","year":"1976","journal-title":"Gastroenterology"},{"key":"10.1016\/j.dld.2025.10.024_bib0006","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1046\/j.1469-7580.2002.00049.x","article-title":"Electrophysiological study of the rectosigmoid canal: evidence of a rectosigmoid sphincter","volume":"200","author":"Shafik","year":"2002","journal-title":"J Anat"},{"key":"10.1016\/j.dld.2025.10.024_bib0007","doi-asserted-by":"crossref","first-page":"3516","DOI":"10.1007\/s10620-020-06657-w","article-title":"The Sphincter of O'Beirne - part 1: study of 18 normal subjects","volume":"66","author":"Chen","year":"2021","journal-title":"Dig Dis Sci"},{"key":"10.1016\/j.dld.2025.10.024_bib0008","doi-asserted-by":"crossref","first-page":"1302","DOI":"10.1001\/archsurg.138.12.1302","article-title":"Colonic propulsive impairment in intractable slow-transit constipation","volume":"138","author":"Bassotti","year":"2003","journal-title":"Arch Surg"},{"key":"10.1016\/j.dld.2025.10.024_bib0009","article-title":"Diagnosis of colonic dysmotility associated with autonomic dysfunction in patients with chronic refractory constipation","volume":"12","author":"Liu","year":"2022","journal-title":"Sci Rep"},{"key":"10.1016\/j.dld.2025.10.024_bib0010","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1111\/1440-1681.12760","article-title":"The \"rectosigmoid brake\": review of an emerging neuromodulation target for colorectal functional disorders","volume":"44","author":"Lin","year":"2017","journal-title":"Clin Exp Pharmacol Physiol"}],"container-title":["Digestive and Liver Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1590865825011831?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1590865825011831?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,2,9]],"date-time":"2026-02-09T16:51:03Z","timestamp":1770655863000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1590865825011831"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1]]},"references-count":10,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,1]]}},"alternative-id":["S1590865825011831"],"URL":"https:\/\/doi.org\/10.1016\/j.dld.2025.10.024","relation":{},"ISSN":["1590-8658"],"issn-type":[{"value":"1590-8658","type":"print"}],"subject":[],"published":{"date-parts":[[2026,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"24-hour colonic manometry can reveal exaggerated rectosigmoid junction (sphincter of O\u2019Beirne) activity in severely constipated patients","name":"articletitle","label":"Article Title"},{"value":"Digestive and Liver Disease","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.dld.2025.10.024","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"simple-article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Editrice Gastroenterologica Italiana S.r.l. Published by Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}