{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,23]],"date-time":"2025-10-23T01:38:18Z","timestamp":1761183498949,"version":"build-2065373602"},"reference-count":9,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2015,6,1]],"date-time":"2015-06-01T00:00:00Z","timestamp":1433116800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2015,6,1]],"date-time":"2015-06-01T00:00:00Z","timestamp":1433116800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Drug Metabolism and Pharmacokinetics"],"published-print":{"date-parts":[[2015,6]]},"DOI":"10.1016\/j.dmpk.2015.02.002","type":"journal-article","created":{"date-parts":[[2015,2,24]],"date-time":"2015-02-24T02:17:59Z","timestamp":1424744279000},"page":"253-256","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"title":["Effect of high fat intake on the pharmacokinetic profile of ivermectin in rabbits"],"prefix":"10.1016","volume":"30","author":[{"given":"Atsushi","family":"Miyajima","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yosuke","family":"Yamamoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takashi","family":"Hirota","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.dmpk.2015.02.002_bib1","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1007\/BF00637608","article-title":"The relative systemic availability of ivermectin after administration as capsule, tablet, and oral solution","volume":"35","author":"Edwards","year":"1988","journal-title":"Eur J Clin Pharmacol"},{"key":"10.1016\/j.dmpk.2015.02.002_bib2","doi-asserted-by":"crossref","first-page":"1122","DOI":"10.1177\/009127002237994","article-title":"Safety, tolerability, and pharmacokinetics of escalating high doses of ivermectin in healthy adult subjects","volume":"42","author":"Guzzo","year":"2002","journal-title":"J\u00a0Clin Pharmacol"},{"key":"10.1016\/j.dmpk.2015.02.002_bib3","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1111\/j.1365-2885.1996.tb00018.x","article-title":"The effect of level of feed intake on the pharmacokinetic disposition and efficacy of ivermectin in sheep","volume":"19","author":"Ali","year":"1996","journal-title":"J\u00a0Vet Pharmacol Ther"},{"key":"10.1016\/j.dmpk.2015.02.002_bib4","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1016\/j.cca.2004.07.011","article-title":"Macrocyclic lactones: distribution in plasma lipoproteins of several animal species including humans","volume":"138","author":"Bassissi","year":"2004","journal-title":"Comp Biochem Physiol C Toxicol Pharmacol"},{"key":"10.1016\/j.dmpk.2015.02.002_bib5","first-page":"661","article-title":"Effect of cholesterol feeding on the thyroid gland and vascular structures of the rabbit, guinea pig, hamster and rat","volume":"41","author":"Bernick","year":"1962","journal-title":"Am J Pathol"},{"key":"10.1016\/j.dmpk.2015.02.002_bib6","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1111\/j.1365-2885.2008.00971.x","article-title":"Pharmacokinetics of ivermectin after maternal or fetal intravenous administration in sheep","volume":"31","author":"P\u00e9rez","year":"2008","journal-title":"J\u00a0Vet Pharmacol Ther"},{"key":"10.1016\/j.dmpk.2015.02.002_bib7","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1111\/1346-8138.12728","article-title":"Experimental study of pharmacokinetics of external, whole body bathing application of ivermectin","volume":"42","author":"Miyajima","year":"2015","journal-title":"J\u00a0Dematol"},{"key":"10.1016\/j.dmpk.2015.02.002_bib8","first-page":"286","article-title":"Analysis program available on Microsoft Excel","volume":"14","author":"Tabata","year":"1999","journal-title":"Xenobio Metab Dispo"},{"key":"10.1016\/j.dmpk.2015.02.002_bib9","doi-asserted-by":"crossref","first-page":"936","DOI":"10.1021\/js9704846","article-title":"Association of halofantrine with postprandially derived plasma lipoproteins decreases its clearance relative to administration in the fasted state","volume":"87","author":"Humberstone","year":"1998","journal-title":"J\u00a0Pharm Sci"}],"container-title":["Drug Metabolism and Pharmacokinetics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1347436715000166?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1347436715000166?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T19:52:02Z","timestamp":1761162722000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1347436715000166"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,6]]},"references-count":9,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2015,6]]}},"alternative-id":["S1347436715000166"],"URL":"https:\/\/doi.org\/10.1016\/j.dmpk.2015.02.002","relation":{},"ISSN":["1347-4367"],"issn-type":[{"type":"print","value":"1347-4367"}],"subject":[],"published":{"date-parts":[[2015,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Effect of high fat intake on the pharmacokinetic profile of ivermectin in rabbits","name":"articletitle","label":"Article Title"},{"value":"Drug Metabolism and Pharmacokinetics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.dmpk.2015.02.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 The Japanese Society for the Study of Xenobiotics. Published by Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}