{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,23]],"date-time":"2025-10-23T01:38:33Z","timestamp":1761183513860,"version":"build-2065373602"},"reference-count":6,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2019,2,1]],"date-time":"2019-02-01T00:00:00Z","timestamp":1548979200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,2,1]],"date-time":"2019-02-01T00:00:00Z","timestamp":1548979200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Drug Metabolism and Pharmacokinetics"],"published-print":{"date-parts":[[2019,2]]},"DOI":"10.1016\/j.dmpk.2018.08.008","type":"journal-article","created":{"date-parts":[[2018,8,28]],"date-time":"2018-08-28T17:56:18Z","timestamp":1535478978000},"page":"108-110","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"title":["The extent of drug-drug interaction between amlodipine and activated charcoal is attenuated by food intake in rats"],"prefix":"10.1016","volume":"34","author":[{"given":"Ayuko","family":"Imaoka","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8845-0265","authenticated-orcid":false,"given":"Kohei","family":"Seki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takeshi","family":"Akiyoshi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4089-9407","authenticated-orcid":false,"given":"Hisakazu","family":"Ohtani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.dmpk.2018.08.008_bib1","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1111\/j.1365-2125.1997.tb00134.x","article-title":"Prevention of amlodipine absorption by activated charcoal: effect of delay in charcoal administration","volume":"43","author":"Laine","year":"1997","journal-title":"Br J Clin Pharmacol"},{"issue":"7","key":"10.1016\/j.dmpk.2018.08.008_bib2","doi-asserted-by":"crossref","first-page":"904","DOI":"10.1177\/0091270007301622","article-title":"Effects of dosing interval on the pharmacokinetic interaction between oral small spherical activated charcoal and amlodipine in humans","volume":"47","author":"Tanaka","year":"2007","journal-title":"J\u00a0Clin Pharmacol"},{"issue":"11","key":"10.1016\/j.dmpk.2018.08.008_bib3","article-title":"Food intake attenuates the drug interaction between new quinolones and aluminum","volume":"4","author":"Imaoka","year":"2018","journal-title":"J\u00a0Pharm Health Care Sci"},{"issue":"11","key":"10.1016\/j.dmpk.2018.08.008_bib4","doi-asserted-by":"crossref","first-page":"3785","DOI":"10.1016\/S0021-9258(17)34757-9","article-title":"Lipid composition of the gastric mucous barrier in the rat","volume":"253","author":"Slomiany","year":"1978","journal-title":"J\u00a0Biol Chem"},{"issue":"10","key":"10.1016\/j.dmpk.2018.08.008_bib5","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1002\/j.1552-4604.1989.tb03260.x","article-title":"Ciprofloxacin pharmacokinetics after a standard or high-fat\/high-calcium breakfast","volume":"29","author":"Frost","year":"1989","journal-title":"J\u00a0Clin Pharmacol"},{"year":"2017","series-title":"Pfizer Japan. \u201cInterview form\u201d (a drug information booklet) of Norvasc tablets 2.5 mg, 5 mg and 10 mg. 21th ed. (in Japanese)","key":"10.1016\/j.dmpk.2018.08.008_bib6"}],"container-title":["Drug Metabolism and Pharmacokinetics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S134743671830079X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S134743671830079X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T19:55:21Z","timestamp":1761162921000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S134743671830079X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,2]]},"references-count":6,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2019,2]]}},"alternative-id":["S134743671830079X"],"URL":"https:\/\/doi.org\/10.1016\/j.dmpk.2018.08.008","relation":{},"ISSN":["1347-4367"],"issn-type":[{"type":"print","value":"1347-4367"}],"subject":[],"published":{"date-parts":[[2019,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The extent of drug-drug interaction between amlodipine and activated charcoal is attenuated by food intake in rats","name":"articletitle","label":"Article Title"},{"value":"Drug Metabolism and Pharmacokinetics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.dmpk.2018.08.008","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Published by Elsevier Ltd on behalf of The Japanese Society for the Study of Xenobiotics.","name":"copyright","label":"Copyright"}]}}