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Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.dnarep.2013.04.015_bib0385","doi-asserted-by":"crossref","first-page":"1429","DOI":"10.1101\/gad.378206","article-title":"CSA-dependent degradation of CSB by the ubiquitin\u2013proteasome pathway establishes a link between complementation factors of the Cockayne syndrome","volume":"20","author":"Groisman","year":"2006","journal-title":"Genes Dev."},{"key":"10.1016\/j.dnarep.2013.04.015_bib0390","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1038\/jid.2011.426","article-title":"Shining a light on xeroderma pigmentosum","volume":"132","author":"DiGiovanna","year":"2012","journal-title":"J. Invest Dermatol."},{"key":"10.1016\/j.dnarep.2013.04.015_bib0395","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1001\/archderm.1987.01660260111026","article-title":"Xeroderma pigmentosum. 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A"},{"key":"10.1016\/j.dnarep.2013.04.015_bib0450","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/S1568-7864(01)00010-6","article-title":"UVB radiation-induced cancer predisposition in Cockayne syndrome group A (Csa) mutant mice","volume":"1","author":"van der Horst","year":"2002","journal-title":"DNA Repair (Amst)"},{"key":"10.1016\/j.dnarep.2013.04.015_bib0455","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1016\/S0092-8674(00)80223-8","article-title":"Defective transcription-coupled repair in Cockayne syndrome B mice is associated with skin cancer predisposition","volume":"89","author":"van der Horst","year":"1997","journal-title":"Cell"},{"key":"10.1016\/j.dnarep.2013.04.015_bib0460","doi-asserted-by":"crossref","first-page":"e1002405","DOI":"10.1371\/journal.pgen.1002405","article-title":"Age-related neuronal degeneration: complementary roles of nucleotide excision repair and transcription-coupled repair in preventing neuropathology","volume":"7","author":"Jaarsma","year":"2011","journal-title":"PLoS Genet."},{"key":"10.1016\/j.dnarep.2013.04.015_bib0465","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1136\/jmg.2008.058743","article-title":"Trichothiodystrophy: a systematic review of 112 published cases characterises a wide spectrum of clinical manifestations","volume":"45","author":"Faghri","year":"2008","journal-title":"J. Med. Genet."},{"key":"10.1016\/j.dnarep.2013.04.015_bib0470","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1086\/428141","article-title":"Identification of C7orf11 (TTDN1) gene mutations and genetic heterogeneity in nonphotosensitive trichothiodystrophy","volume":"76","author":"Nakabayashi","year":"2005","journal-title":"Am. J. Hum. Genet."},{"key":"10.1016\/j.dnarep.2013.04.015_bib0475","doi-asserted-by":"crossref","first-page":"714","DOI":"10.1038\/ng1387","article-title":"A new, tenth subunit of TFIIH is responsible for the DNA repair syndrome trichothiodystrophy group A","volume":"36","author":"Giglia-Mari","year":"2004","journal-title":"Nat. Genet."},{"key":"10.1016\/j.dnarep.2013.04.015_bib0480","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/j.molcel.2005.10.024","article-title":"p8\/TTD-A as a repair-specific TFIIH subunit","volume":"21","author":"Coin","year":"2006","journal-title":"Mol. 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Ageing Dev."},{"key":"10.1016\/j.dnarep.2013.04.015_bib0565","doi-asserted-by":"crossref","first-page":"1442","DOI":"10.1016\/j.dnarep.2005.09.004","article-title":"Molecular and biological roles of Ape1 protein in mammalian base excision repair","volume":"4","author":"Demple","year":"2005","journal-title":"DNA Repair (Amst)"},{"key":"10.1016\/j.dnarep.2013.04.015_bib0570","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1016\/S0921-8777(01)00063-5","article-title":"The major human abasic endonuclease: formation, consequences and repair of abasic lesions in DNA","volume":"485","author":"Wilson","year":"2001","journal-title":"Mutat. Res."},{"key":"10.1016\/j.dnarep.2013.04.015_bib0575","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1038\/35000249","article-title":"DNA-bound structures and mutants reveal abasic DNA binding by APE1 and DNA repair coordination","volume":"403","author":"Mol","year":"2000","journal-title":"Nature"},{"key":"10.1016\/j.dnarep.2013.04.015_bib0580","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/S0921-8777(98)00002-0","article-title":"Mammalian base excision repair and DNA polymerase beta","volume":"407","author":"Wilson","year":"1998","journal-title":"Mutat. Res."},{"key":"10.1016\/j.dnarep.2013.04.015_bib0585","doi-asserted-by":"crossref","first-page":"7166","DOI":"10.1073\/pnas.94.14.7166","article-title":"Interaction of human apurinic endonuclease and DNA polymerase beta in the base excision repair pathway","volume":"94","author":"Bennett","year":"1997","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.dnarep.2013.04.015_bib0590","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/j.molcel.2004.06.003","article-title":"AP endonuclease-independent DNA base excision repair in human cells","volume":"15","author":"Wiederhold","year":"2004","journal-title":"Mol. Cell"},{"key":"10.1016\/j.dnarep.2013.04.015_bib0595","doi-asserted-by":"crossref","first-page":"6905","DOI":"10.1073\/pnas.0400099101","article-title":"Stable down-regulation of human polynucleotide kinase enhances spontaneous mutation frequency and sensitizes cells to genotoxic agents","volume":"101","author":"Rasouli-Nia","year":"2004","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.dnarep.2013.04.015_bib0600","doi-asserted-by":"crossref","first-page":"4354","DOI":"10.1074\/jbc.274.7.4354","article-title":"Proliferating cell nuclear antigen facilitates excision in long-patch base excision repair","volume":"274","author":"Gary","year":"1999","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.dnarep.2013.04.015_bib0605","doi-asserted-by":"crossref","first-page":"1121","DOI":"10.1016\/j.freeradbiomed.2005.01.012","article-title":"Protein\u2013protein interactions and posttranslational modifications in mammalian base excision repair","volume":"38","author":"Fan","year":"2005","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.dnarep.2013.04.015_bib0610","doi-asserted-by":"crossref","first-page":"55196","DOI":"10.1074\/jbc.M409250200","article-title":"A conserved interaction between the replicative clamp loader and DNA ligase in eukaryotes: implications for Okazaki fragment joining","volume":"279","author":"Levin","year":"2004","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.dnarep.2013.04.015_bib0615","doi-asserted-by":"crossref","first-page":"919","DOI":"10.1016\/S0960-9822(00)00619-9","article-title":"Interaction between PCNA and DNA ligase I is critical for joining of Okazaki fragments and long-patch base-excision repair","volume":"10","author":"Levin","year":"2000","journal-title":"Curr. Biol."},{"key":"10.1016\/j.dnarep.2013.04.015_bib0620","doi-asserted-by":"crossref","first-page":"3786","DOI":"10.1093\/emboj\/17.13.3786","article-title":"DNA ligase I is recruited to sites of DNA replication by an interaction with proliferating cell nuclear antigen: identification of a common targeting mechanism for the assembly of replication factories","volume":"17","author":"Montecucco","year":"1998","journal-title":"EMBO J."},{"key":"10.1016\/j.dnarep.2013.04.015_bib0625","doi-asserted-by":"crossref","first-page":"834","DOI":"10.1016\/j.dnarep.2009.04.002","article-title":"Extracts of proliferating and non-proliferating human cells display different base excision pathways and repair fidelity","volume":"8","author":"Akbari","year":"2009","journal-title":"DNA Repair (Amst)"},{"key":"10.1016\/j.dnarep.2013.04.015_bib0630","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1016\/j.dnarep.2006.11.001","article-title":"MUTYH-associated polyposis\u2014from defect in base excision repair to clinical genetic testing","volume":"6","author":"Cheadle","year":"2007","journal-title":"DNA Repair (Amst)"},{"key":"10.1016\/j.dnarep.2013.04.015_bib0635","doi-asserted-by":"crossref","first-page":"1023","DOI":"10.1038\/ni974","article-title":"Human uracil\u2013DNA glycosylase deficiency associated with profoundly impaired immunoglobulin class-switch recombination","volume":"4","author":"Imai","year":"2003","journal-title":"Nat. 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Blood Flow Metab."},{"key":"10.1016\/j.dnarep.2013.04.015_bib0665","doi-asserted-by":"crossref","first-page":"1711","DOI":"10.1172\/JCI200420926","article-title":"Increased postischemic brain injury in mice deficient in uracil\u2013DNA glycosylase","volume":"113","author":"Endres","year":"2004","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.dnarep.2013.04.015_bib0670","doi-asserted-by":"crossref","first-page":"13649","DOI":"10.1073\/pnas.250477597","article-title":"Mutation of a BRCT domain selectively disrupts DNA single-strand break repair in noncycling Chinese hamster ovary cells","volume":"97","author":"Moore","year":"2000","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.dnarep.2013.04.015_bib0675","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1126\/science.286.5439.552","article-title":"Yeast gene for a Tyr-DNA phosphodiesterase that repairs topoisomerase I complexes","volume":"286","author":"Pouliot","year":"1999","journal-title":"Science"},{"key":"10.1016\/j.dnarep.2013.04.015_bib0680","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1093\/nar\/gki170","article-title":"Deficiency in 3\u2032-phosphoglycolate processing in human cells with a hereditary mutation in tyrosyl-DNA phosphodiesterase (TDP1)","volume":"33","author":"Zhou","year":"2005","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.dnarep.2013.04.015_bib0685","doi-asserted-by":"crossref","first-page":"2495","DOI":"10.1093\/nar\/25.12.2495","article-title":"3\u2032-Phosphodiesterase activity of human apurinic\/apyrimidinic endonuclease at DNA double-strand break ends","volume":"25","author":"Suh","year":"1997","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.dnarep.2013.04.015_bib0690","doi-asserted-by":"crossref","first-page":"3797","DOI":"10.1093\/nar\/gkm158","article-title":"Aprataxin, causative gene product for EAOH\/AOA1, repairs DNA single-strand breaks with damaged 3\u2019-phosphate and 3\u2019-phosphoglycolate ends","volume":"35","author":"Takahashi","year":"2007","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.dnarep.2013.04.015_bib0695","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1038\/ng987","article-title":"Mutation of TDP1, encoding a topoisomerase I-dependent DNA damage repair enzyme, in spinocerebellar ataxia with axonal neuropathy","volume":"32","author":"Takashima","year":"2002","journal-title":"Nat. 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Genet."},{"key":"10.1016\/j.dnarep.2013.04.015_bib0730","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1038\/ng1001-184","article-title":"Early-onset ataxia with ocular motor apraxia and hypoalbuminemia is caused by mutations in a new HIT superfamily gene","volume":"29","author":"Date","year":"2001","journal-title":"Nat. Genet."},{"key":"10.1016\/j.dnarep.2013.04.015_bib0735","first-page":"1081","article-title":"Aprataxin, a novel protein that protects against genotoxic stress, Hum","volume":"13","author":"Gueven","year":"2004","journal-title":"Mol. Genet."},{"key":"10.1016\/j.dnarep.2013.04.015_bib0740","doi-asserted-by":"crossref","first-page":"2239","DOI":"10.1093\/hmg\/ddl149","article-title":"Nucleolar localization of aprataxin is dependent on interaction with nucleolin and on active ribosomal DNA transcription","volume":"15","author":"Becherel","year":"2006","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.dnarep.2013.04.015_bib0745","first-page":"3533","article-title":"Protein kinase C gamma, a protein causative for dominant ataxia, negatively regulates nuclear import of recessive-ataxia-related aprataxin, Hum","volume":"18","author":"Asai","year":"2009","journal-title":"Mol. Genet."},{"key":"10.1016\/j.dnarep.2013.04.015_bib0750","doi-asserted-by":"crossref","first-page":"7437","DOI":"10.1073\/pnas.1100084108","article-title":"Aprataxin localizes to mitochondria and preserves mitochondrial function","volume":"108","author":"Sykora","year":"2011","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.dnarep.2013.04.015_bib0755","doi-asserted-by":"crossref","first-page":"8356","DOI":"10.1128\/MCB.24.19.8356-8365.2004","article-title":"A new XRCC1-containing complex and its role in cellular survival of methyl methanesulfonate treatment","volume":"24","author":"Luo","year":"2004","journal-title":"Mol. Cell Biol."},{"key":"10.1016\/j.dnarep.2013.04.015_bib0760","doi-asserted-by":"crossref","first-page":"760","DOI":"10.1016\/j.dnarep.2009.02.002","article-title":"Synergistic decrease of DNA single-strand break repair rates in mouse neural cells lacking both Tdp1 and aprataxin","volume":"8","author":"El-Khamisy","year":"2009","journal-title":"DNA Repair (Amst)"},{"key":"10.1016\/j.dnarep.2013.04.015_bib0765","doi-asserted-by":"crossref","first-page":"1493","DOI":"10.1016\/j.dnarep.2004.06.017","article-title":"The ataxia-oculomotor apraxia 1 gene product has a role distinct from ATM and interacts with the DNA strand break repair proteins XRCC1 and XRCC4","volume":"3","author":"Clements","year":"2004","journal-title":"DNA Repair (Amst)"},{"key":"10.1016\/j.dnarep.2013.04.015_bib0770","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1038\/ng.526","article-title":"Mutations in PNKP cause microcephaly, seizures and defects in DNA repair","volume":"42","author":"Shen","year":"2010","journal-title":"Nat. Genet."},{"key":"10.1016\/j.dnarep.2013.04.015_bib0775","doi-asserted-by":"crossref","first-page":"6608","DOI":"10.1093\/nar\/gks318","article-title":"Impact of PNKP mutations associated with microcephaly, seizures and developmental delay on enzyme activity and DNA strand break repair","volume":"40","author":"Reynolds","year":"2012","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.dnarep.2013.04.015_bib0780","doi-asserted-by":"crossref","first-page":"730","DOI":"10.1016\/j.cell.2010.05.002","article-title":"SnapShot: DNA mismatch repair","volume":"141","author":"Larrea","year":"2010","journal-title":"Cell"},{"key":"10.1016\/j.dnarep.2013.04.015_bib0785","doi-asserted-by":"crossref","first-page":"10759","DOI":"10.1158\/0008-5472.CAN-05-2528","article-title":"Expression of the MutL homologue hMLH3 in human cells and its role in DNA mismatch repair","volume":"65","author":"Cannavo","year":"2005","journal-title":"Cancer Res."},{"key":"10.1016\/j.dnarep.2013.04.015_bib0790","doi-asserted-by":"crossref","first-page":"32368","DOI":"10.1074\/jbc.274.45.32368","article-title":"Identification of hMutLbeta, a heterodimer of hMLH1 and hPMS1","volume":"274","author":"Raschle","year":"1999","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.dnarep.2013.04.015_bib0795","doi-asserted-by":"crossref","first-page":"4135","DOI":"10.1073\/pnas.73.11.4135","article-title":"Repair tracts in mismatched DNA heteroduplexes","volume":"73","author":"Wagner","year":"1976","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.dnarep.2013.04.015_bib0800","doi-asserted-by":"crossref","first-page":"16066","DOI":"10.1073\/pnas.1010662107","article-title":"PCNA function in the activation and strand direction of MutLalpha endonuclease in mismatch repair","volume":"107","author":"Pluciennik","year":"2010","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.dnarep.2013.04.015_bib0805","doi-asserted-by":"crossref","first-page":"21070","DOI":"10.1073\/pnas.1013048107","article-title":"Differential correction of lagging-strand replication errors made by DNA polymerases {alpha} and {delta}","volume":"107","author":"Nick McElhinny","year":"2010","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.dnarep.2013.04.015_bib0810","doi-asserted-by":"crossref","first-page":"20935","DOI":"10.1074\/jbc.M401931200","article-title":"Evidence for involvement of HMGB1 protein in human DNA mismatch repair","volume":"279","author":"Yuan","year":"2004","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.dnarep.2013.04.015_bib0815","doi-asserted-by":"crossref","first-page":"2751","DOI":"10.1056\/NEJMoa053493","article-title":"Identification and survival of carriers of mutations in DNA mismatch-repair genes in colon cancer","volume":"354","author":"Barnetson","year":"2006","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.dnarep.2013.04.015_bib0820","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/S0300-9084(01)01362-1","article-title":"DNA mismatch repair defects: role in colorectal carcinogenesis","volume":"84","author":"Jacob","year":"2002","journal-title":"Biochimie"},{"key":"10.1016\/j.dnarep.2013.04.015_bib0825","doi-asserted-by":"crossref","first-page":"1431","DOI":"10.1053\/j.gastro.2005.04.008","article-title":"Familial mutations in PMS2 can cause autosomal dominant hereditary nonpolyposis colorectal cancer","volume":"128","author":"Worthley","year":"2005","journal-title":"Gastroenterology"},{"key":"10.1016\/j.dnarep.2013.04.015_bib0830","doi-asserted-by":"crossref","first-page":"3221","DOI":"10.1158\/1078-0432.CCR-06-3064","article-title":"Distinction of hereditary nonpolyposis colorectal cancer and sporadic microsatellite-unstable colorectal cancer through quantification of MLH1 methylation by real-time PCR","volume":"13","author":"Bettstetter","year":"2007","journal-title":"Clin. Cancer Res."},{"key":"10.1016\/j.dnarep.2013.04.015_bib0835","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1155\/2004\/305058","article-title":"Mutations associated with HNPCC predisposition\u2014update of ICG-HNPCC\/INSiGHT mutation database","volume":"20","author":"Peltomaki","year":"2004","journal-title":"Dis. Markers"},{"key":"10.1016\/j.dnarep.2013.04.015_bib0840","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1002\/ijc.11176","article-title":"Role of hMLH1 promoter hypermethylation in drug resistance to 5-fluorouracil in colorectal cancer cell lines","volume":"106","author":"Arnold","year":"2003","journal-title":"Int. J. Cancer"},{"key":"10.1016\/j.dnarep.2013.04.015_bib0845","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1038\/ng0398-276","article-title":"Tumour susceptibility and spontaneous mutation in mice deficient in Mlh1, Pms1 and Pms2 DNA mismatch repair","volume":"18","author":"Prolla","year":"1998","journal-title":"Nat. Genet."},{"key":"10.1016\/j.dnarep.2013.04.015_bib0850","doi-asserted-by":"crossref","first-page":"1323","DOI":"10.1016\/S0306-4522(99)00380-2","article-title":"Distribution and kainate-mediated induction of the DNA mismatch repair protein MSH2 in rat brain","volume":"94","author":"Belloni","year":"1999","journal-title":"Neuroscience"},{"key":"10.1016\/j.dnarep.2013.04.015_bib0855","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/S0027-5107(02)00222-1","article-title":"DNA repair in neural cells: basic science and clinical implications","volume":"509","author":"Brooks","year":"2002","journal-title":"Mutat. Res."},{"key":"10.1016\/j.dnarep.2013.04.015_bib0860","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1523\/JNEUROSCI.16-03-00939.1996","article-title":"DNA mismatch repair and DNA methylation in adult brain neurons","volume":"16","author":"Brooks","year":"1996","journal-title":"J. Neurosci."},{"key":"10.1016\/j.dnarep.2013.04.015_bib0865","first-page":"747","article-title":"Potential role of MLH1 in the induction of p53 and apoptosis by blocking transcription on damaged DNA templates","volume":"1","author":"Yanamadala","year":"2003","journal-title":"Mol. Cancer Res."},{"key":"10.1016\/j.dnarep.2013.04.015_bib0870","first-page":"1392","article-title":"Involvement of mammalian MLH1 in the apoptotic response to peroxide-induced oxidative stress","volume":"61","author":"Hardman","year":"2001","journal-title":"Cancer Res."},{"key":"10.1016\/j.dnarep.2013.04.015_bib0875","doi-asserted-by":"crossref","first-page":"8292","DOI":"10.1128\/MCB.19.12.8292","article-title":"Mismatch repair processing of carcinogen-DNA adducts triggers apoptosis","volume":"19","author":"Wu","year":"1999","journal-title":"Mol. Cell Biol."},{"key":"10.1016\/j.dnarep.2013.04.015_bib0880","doi-asserted-by":"crossref","first-page":"10764","DOI":"10.1073\/pnas.96.19.10764","article-title":"Role of DNA mismatch repair and p53 in signaling induction of apoptosis by alkylating agents","volume":"96","author":"Hickman","year":"1999","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.dnarep.2013.04.015_bib0885","doi-asserted-by":"crossref","first-page":"3911","DOI":"10.1073\/pnas.96.7.3911","article-title":"Msh2 status modulates both apoptosis and mutation frequency in the murine small intestine","volume":"96","author":"Toft","year":"1999","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.dnarep.2013.04.015_bib0890","doi-asserted-by":"crossref","first-page":"11915","DOI":"10.1073\/pnas.95.20.11915","article-title":"Mouse embryonic stem cells carrying one or two defective Msh2 alleles respond abnormally to oxidative stress inflicted by low-level radiation","volume":"95","author":"DeWeese","year":"1998","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.dnarep.2013.04.015_bib0895","first-page":"4889","article-title":"Ionizing radiation-induced apoptosis via separate Pms2- and p53-dependent pathways","volume":"60","author":"Zeng","year":"2000","journal-title":"Cancer Res."},{"key":"10.1016\/j.dnarep.2013.04.015_bib0900","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1186\/2041-9414-1-15","article-title":"DNA double-strand break signaling and human disorders","volume":"1","author":"Bohgaki","year":"2010","journal-title":"Genome Integr."},{"key":"10.1016\/j.dnarep.2013.04.015_bib0905","doi-asserted-by":"crossref","first-page":"1071","DOI":"10.1038\/nature08467","article-title":"The DNA-damage response in human biology and disease","volume":"461","author":"Jackson","year":"2009","journal-title":"Nature"},{"key":"10.1016\/j.dnarep.2013.04.015_bib0910","doi-asserted-by":"crossref","first-page":"1227","DOI":"10.1016\/j.dnarep.2004.03.025","article-title":"An overview of three new disorders associated with genetic instability: LIG4 syndrome, RS-SCID and ATR-Seckel syndrome","volume":"3","author":"O\u2019Driscoll","year":"2004","journal-title":"DNA Repair (Amst)"},{"key":"10.1016\/j.dnarep.2013.04.015_bib0915","doi-asserted-by":"crossref","first-page":"1187","DOI":"10.1016\/S1097-2765(01)00425-7","article-title":"Impaired nonhomologous end-joining provokes soft tissue sarcomas harboring chromosomal translocations, amplifications, and deletions","volume":"8","author":"Sharpless","year":"2001","journal-title":"Mol. 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Med."},{"key":"10.1016\/j.dnarep.2013.04.015_bib0930","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1038\/35077232","article-title":"Genome maintenance mechanisms for preventing cancer","volume":"411","author":"Hoeijmakers","year":"2001","journal-title":"Nature"},{"key":"10.1016\/j.dnarep.2013.04.015_bib0935","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1159\/000086896","article-title":"Effect of meiotic recombination on the production of aneuploid gametes in humans","volume":"111","author":"Lamb","year":"2005","journal-title":"Cytogenet. Genome Res."},{"key":"10.1016\/j.dnarep.2013.04.015_bib0940","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1038\/nrm3047","article-title":"The MRE11 complex: starting from the ends","volume":"12","author":"Stracker","year":"2011","journal-title":"Nat. Rev. Mol. 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Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.dnarep.2013.04.015_bib0985","doi-asserted-by":"crossref","first-page":"2767","DOI":"10.1101\/gad.503108","article-title":"DNA helicases Sgs1 and BLM promote DNA double-strand break resection","volume":"22","author":"Gravel","year":"2008","journal-title":"Genes Dev."},{"key":"10.1016\/j.dnarep.2013.04.015_bib0990","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1006\/jmbi.2000.4180","article-title":"Reconstitution of the strand invasion step of double-strand break repair using human Rad51 Rad52 and RPA proteins","volume":"304","author":"McIlwraith","year":"2000","journal-title":"J. Mol. Biol."},{"key":"10.1016\/j.dnarep.2013.04.015_bib0995","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1016\/j.molcel.2007.11.037","article-title":"DNA repair synthesis facilitates RAD52-mediated second-end capture during DSB repair","volume":"29","author":"McIlwraith","year":"2008","journal-title":"Mol. 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Biol. Chem."},{"key":"10.1016\/j.dnarep.2013.04.015_bib1030","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1016\/j.molcel.2005.10.001","article-title":"Human DNA polymerase eta promotes DNA synthesis from strand invasion intermediates of homologous recombination","volume":"20","author":"McIlwraith","year":"2005","journal-title":"Mol. 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