{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T12:10:43Z","timestamp":1790770243184,"version":"4.1.0"},"reference-count":29,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,1,1]],"date-time":"2018-01-01T00:00:00Z","timestamp":1514764800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"name":"University of Oslo to LE"},{"name":"Norwegian Financial Mechanism","award":["2009-2014"],"award-info":[{"award-number":["2009-2014"]}]},{"DOI":"10.13039\/501100001823","name":"Ministry of Education, Youth and Sports","doi-asserted-by":"crossref","award":["MSMT-28477\/2014"],"award-info":[{"award-number":["MSMT-28477\/2014"]}],"id":[{"id":"10.13039\/501100001823","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Liaison Committee between the Central Norway Regional Health Authority (RHA)"},{"name":"Norwegian University of Science and Technology (NTNU)","award":["46040500"],"award-info":[{"award-number":["46040500"]}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["DNA Repair"],"published-print":{"date-parts":[[2018,1]]},"DOI":"10.1016\/j.dnarep.2017.11.008","type":"journal-article","created":{"date-parts":[[2017,11,29]],"date-time":"2017-11-29T04:15:59Z","timestamp":1511928959000},"page":"56-62","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":17,"special_numbering":"C","title":["8-oxoguanine DNA glycosylase (Ogg1) controls hepatic gluconeogenesis"],"prefix":"10.1016","volume":"61","author":[{"given":"Katja","family":"Scheffler","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lyudmila","family":"Rachek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Panpan","family":"You","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander D.","family":"Rowe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Ku\u015bnierczyk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lene","family":"Kittelsen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Magnar","family":"Bj\u00f8r\u00e5s","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lars","family":"Eide","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.dnarep.2017.11.008_bib0005","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1016\/j.dnarep.2015.04.029","article-title":"The role of DNA base excision repair in brain homeostasis and disease","volume":"32","author":"Akbari","year":"2015","journal-title":"DNA Repair (Amst)"},{"key":"10.1016\/j.dnarep.2017.11.008_bib0010","first-page":"5378","article-title":"Repair of 8-oxodeoxyguanosine lesions in mitochondrial dna depends on the oxoguanine dna glycosylase (OGG1) gene and 8-oxoguanine accumulates in the mitochondrial dna of OGG1-defective mice","volume":"61","author":"de Souza-Pinto","year":"2001","journal-title":"Cancer Res."},{"key":"10.1016\/j.dnarep.2017.11.008_bib0015","doi-asserted-by":"crossref","first-page":"3096","DOI":"10.1158\/0008-5472.CAN-03-3834","article-title":"Deficiencies in mouse Myh and Ogg1 result in tumor predisposition and G to T mutations in codon 12 of the K-ras oncogene in lung tumors","volume":"64","author":"Xie","year":"2004","journal-title":"Cancer Res."},{"key":"10.1016\/j.dnarep.2017.11.008_bib0020","doi-asserted-by":"crossref","first-page":"1355","DOI":"10.1093\/nar\/28.6.1355","article-title":"Identification of human MutY homolog (hMYH) as a repair enzyme for 2-hydroxyadenine in DNA and detection of multiple forms of hMYH located in nuclei and mitochondria","volume":"28","author":"Ohtsubo","year":"2000","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.dnarep.2017.11.008_bib0025","doi-asserted-by":"crossref","first-page":"1637","DOI":"10.1091\/mbc.10.5.1637","article-title":"Expression and differential intracellular localization of two major forms of human 8-oxoguanine DNA glycosylase encoded by alternatively spliced OGG1 mRNAs","volume":"10","author":"Nishioka","year":"1999","journal-title":"Mol. Biol. Cell"},{"key":"10.1016\/j.dnarep.2017.11.008_bib0030","doi-asserted-by":"crossref","first-page":"4411","DOI":"10.1158\/0008-5472.CAN-04-0355","article-title":"Accumulation of the oxidative base lesion 8-hydroxyguanine in DNA of tumor-prone mice defective in both the Myh and Ogg1 DNA glycosylases","volume":"64","author":"Russo","year":"2004","journal-title":"Cancer Res."},{"key":"10.1016\/j.dnarep.2017.11.008_bib0035","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1016\/j.dnarep.2011.12.001","article-title":"Lack of the DNA glycosylases MYH and OGG1 in the cancer prone double mutant mouse does not increase mitochondrial DNA mutagenesis","volume":"11","author":"Halsne","year":"2012","journal-title":"DNA Repair (Amst)"},{"key":"10.1016\/j.dnarep.2017.11.008_bib0040","doi-asserted-by":"crossref","first-page":"E724","DOI":"10.1152\/ajpendo.00387.2010","article-title":"Variable penetrance of metabolic phenotypes and development of high-fat diet-induced adiposity in NEIL1-deficient mice","volume":"300","author":"Sampath","year":"2011","journal-title":"Am. J. Physiol. Endocrinol. Metab."},{"key":"10.1016\/j.dnarep.2017.11.008_bib0045","doi-asserted-by":"crossref","first-page":"e51697","DOI":"10.1371\/journal.pone.0051697","article-title":"8-Oxoguanine DNA glycosylase (OGG1) deficiency increases susceptibility to obesity and metabolic dysfunction","volume":"7","author":"Sampath","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.dnarep.2017.11.008_bib0050","doi-asserted-by":"crossref","first-page":"882","DOI":"10.1016\/j.cell.2014.03.026","article-title":"Defective mitophagy in XPA via PARP-1 hyperactivation and NAD(+)\/SIRT1 reduction","volume":"157","author":"Fang","year":"2014","journal-title":"Cell"},{"key":"10.1016\/j.dnarep.2017.11.008_bib0055","doi-asserted-by":"crossref","first-page":"3713","DOI":"10.1210\/en.2005-0378","article-title":"Minireview: the role of oxidative stress in relation to caloric restriction and longevity","volume":"146","author":"Gredilla","year":"2005","journal-title":"Endocrinology"},{"key":"10.1016\/j.dnarep.2017.11.008_bib0060","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1007\/s10863-004-9001-7","article-title":"Protein restriction without strong caloric restriction decreases mitochondrial oxygen radical production and oxidative DNA damage in rat liver","volume":"36","author":"Sanz","year":"2004","journal-title":"J. Bioenerg. Biomembr."},{"key":"10.1016\/j.dnarep.2017.11.008_bib0065","article-title":"Metabolism and DNA repair shape a specific modification pattern in mitochondrial DNA","author":"Pawar","year":"2017","journal-title":"Mitochondrion"},{"key":"10.1016\/j.dnarep.2017.11.008_bib0070","doi-asserted-by":"crossref","first-page":"9746","DOI":"10.1523\/JNEUROSCI.0852-11.2011","article-title":"Mitochondrial DNA damage level determines neural stem cell differentiation fate","volume":"31","author":"Wang","year":"2011","journal-title":"J. Neurosci."},{"key":"10.1016\/j.dnarep.2017.11.008_bib0075","doi-asserted-by":"crossref","first-page":"2195","DOI":"10.1002\/stem.542","article-title":"Mitochondrial DNA integrity is essential for mitochondrial maturation during differentiation of neural stem cells","volume":"28","author":"Wang","year":"2010","journal-title":"Stem Cells"},{"key":"10.1016\/j.dnarep.2017.11.008_bib0080","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1038\/35093050","article-title":"Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1","volume":"413","author":"Yoon","year":"2001","journal-title":"Nature"},{"key":"10.1016\/j.dnarep.2017.11.008_bib0085","doi-asserted-by":"crossref","first-page":"490","DOI":"10.18632\/oncotarget.6357","article-title":"Down-regulation of oxidative phosphorylation in the liver by expression of the ATPase inhibitory factor 1 induces a tumor-promoter metabolic state","volume":"7","author":"Santacatterina","year":"2016","journal-title":"Oncotarget"},{"key":"10.1016\/j.dnarep.2017.11.008_bib0090","doi-asserted-by":"crossref","first-page":"28191","DOI":"10.1074\/jbc.M109.082883","article-title":"Neurons efficiently repair glutamate-induced oxidative DNA damage by a process involving CREB-mediated up-regulation of apurinic endonuclease 1","volume":"285","author":"Yang","year":"2010","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.dnarep.2017.11.008_bib0095","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1038\/nature07349","article-title":"A fasting inducible switch modulates gluconeogenesis via activator\/coactivator exchange","volume":"456","author":"Liu","year":"2008","journal-title":"Nature"},{"key":"10.1016\/j.dnarep.2017.11.008_bib0100","doi-asserted-by":"crossref","first-page":"30632","DOI":"10.1074\/jbc.M801401200","article-title":"Human glyceraldehyde-3-phosphate dehydrogenase plays a direct role in reactivating oxidized forms of the DNA repair enzyme APE1","volume":"283","author":"Azam","year":"2008","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.dnarep.2017.11.008_bib0105","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1016\/j.freeradbiomed.2004.12.003","article-title":"No evidence of mitochondrial respiratory dysfunction in OGG1-null mice deficient in removal of 8-oxodeoxyguanine from mitochondrial DNA","volume":"38","author":"Stuart","year":"2005","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.dnarep.2017.11.008_bib0110","doi-asserted-by":"crossref","first-page":"1916","DOI":"10.1126\/science.1140958","article-title":"Restriction of DNA replication to the reductive phase of the metabolic cycle protects genome integrity","volume":"316","author":"Chen","year":"2007","journal-title":"Science"},{"key":"10.1016\/j.dnarep.2017.11.008_bib0115","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1080\/10715760500250182","article-title":"Effects of fasting on oxidative stress in rat liver mitochondria","volume":"40","author":"Sorensen","year":"2006","journal-title":"Free Radic. Res."},{"key":"10.1016\/j.dnarep.2017.11.008_bib0120","doi-asserted-by":"crossref","first-page":"1589","DOI":"10.1096\/fj.00-0764fje","article-title":"Caloric restriction decreases mitochondrial free radical generation at complex I and lowers oxidative damage to mitochondrial DNA in the rat heart","volume":"15","author":"Gredilla","year":"2001","journal-title":"FASEB J."},{"key":"10.1016\/j.dnarep.2017.11.008_bib0125","doi-asserted-by":"crossref","first-page":"1468","DOI":"10.4161\/auto.29321","article-title":"Contribution of defective mitophagy to the neurodegeneration in DNA repair-deficient disorders","volume":"10","author":"Scheibye-Knudsen","year":"2014","journal-title":"Autophagy"},{"key":"10.1016\/j.dnarep.2017.11.008_bib0130","doi-asserted-by":"crossref","first-page":"5596","DOI":"10.1093\/nar\/gkh863","article-title":"The C-terminal alphaO helix of human Ogg1 is essential for 8-oxoguanine DNA glycosylase activity: the mitochondrial beta-Ogg1 lacks this domain and does not have glycosylase activity","volume":"32","author":"Hashiguchi","year":"2004","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.dnarep.2017.11.008_bib0135","doi-asserted-by":"crossref","first-page":"10670","DOI":"10.1073\/pnas.1932854100","article-title":"Age-dependent deficiency in import of mitochondrial DNA glycosylases required for repair of oxidatively damaged bases","volume":"100","author":"Szczesny","year":"2003","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.dnarep.2017.11.008_bib0140","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/j.gene.2012.05.025","article-title":"The role of GSTM1, GSTT1, GSTP1, and OGG1 polymorphisms in type 2 diabetes mellitus risk: a case-control study in a Turkish population","volume":"505","author":"Gonul","year":"2012","journal-title":"Gene"},{"key":"10.1016\/j.dnarep.2017.11.008_bib0145","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.bbrc.2009.05.119","article-title":"Association of the Ser326Cys polymorphism in the OGG1 gene with type 2 DM","volume":"386","author":"Daimon","year":"2009","journal-title":"Biochem. Biophys. Res. Commun."}],"container-title":["DNA Repair"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1568786417302471?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1568786417302471?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,7,14]],"date-time":"2022-07-14T08:19:54Z","timestamp":1657786794000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1568786417302471"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,1]]},"references-count":29,"alternative-id":["S1568786417302471"],"URL":"https:\/\/doi.org\/10.1016\/j.dnarep.2017.11.008","relation":{},"ISSN":["1568-7864"],"issn-type":[{"value":"1568-7864","type":"print"}],"subject":[],"published":{"date-parts":[[2018,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"8-oxoguanine DNA glycosylase (Ogg1) controls hepatic gluconeogenesis","name":"articletitle","label":"Article Title"},{"value":"DNA Repair","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.dnarep.2017.11.008","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}