{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T05:36:43Z","timestamp":1783489003749,"version":"3.55.0"},"reference-count":73,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,10,1]],"date-time":"2018-10-01T00:00:00Z","timestamp":1538352000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,10,1]],"date-time":"2018-10-01T00:00:00Z","timestamp":1538352000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100000654","name":"Marie Curie","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000654","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["K99\/R00 HD069458"],"award-info":[{"award-number":["K99\/R00 HD069458"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01 GM117155"],"award-info":[{"award-number":["R01 GM117155"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["CA009110"],"award-info":[{"award-number":["CA009110"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004963","name":"Seventh Framework Programme","doi-asserted-by":"publisher","award":["CIG 293765"],"award-info":[{"award-number":["CIG 293765"]}],"id":[{"id":"10.13039\/501100004963","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["DNA Repair"],"published-print":{"date-parts":[[2018,10]]},"DOI":"10.1016\/j.dnarep.2018.08.027","type":"journal-article","created":{"date-parts":[[2018,8,28]],"date-time":"2018-08-28T18:18:16Z","timestamp":1535480296000},"page":"55-66","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":25,"special_numbering":"C","title":["The influence of retinoic acid-induced differentiation on the radiation response of male germline stem cells"],"prefix":"10.1016","volume":"70","author":[{"given":"Yi","family":"Zheng","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qijing","family":"Lei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8948-2549","authenticated-orcid":false,"given":"Aldo","family":"Jongejan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Callista L.","family":"Mulder","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saskia K.M.","family":"van Daalen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7550-2924","authenticated-orcid":false,"given":"Sebastiaan","family":"Mastenbroek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4979-4409","authenticated-orcid":false,"given":"Grace","family":"Hwang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4890-2647","authenticated-orcid":false,"given":"Philip W.","family":"Jordan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sjoerd","family":"Repping","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9583-6796","authenticated-orcid":false,"given":"Geert","family":"Hamer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.dnarep.2018.08.027_bib0005","doi-asserted-by":"crossref","first-page":"1838","DOI":"10.1016\/j.bbadis.2012.02.008","article-title":"Molecular control of rodent spermatogenesis","volume":"1822","author":"Jan","year":"2012","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.dnarep.2018.08.027_bib0010","doi-asserted-by":"crossref","first-page":"11303","DOI":"10.1073\/pnas.91.24.11303","article-title":"Germline transmission of donor haplotype following spermatogonial transplantation","volume":"91","author":"Brinster","year":"1994","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.dnarep.2018.08.027_bib0015","doi-asserted-by":"crossref","first-page":"11298","DOI":"10.1073\/pnas.91.24.11298","article-title":"Spermatogenesis following male germ-cell transplantation","volume":"91","author":"Brinster","year":"1994","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.dnarep.2018.08.027_bib0020","doi-asserted-by":"crossref","first-page":"776","DOI":"10.1002\/j.1939-4640.2000.tb03408.x","article-title":"All you wanted to know about spermatogonia but were afraid to ask","volume":"21","author":"de Rooij","year":"2000","journal-title":"J. Androl."},{"key":"10.1016\/j.dnarep.2018.08.027_bib0025","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1038\/sj.cdd.4400396","article-title":"The role of the tumor suppressor p53 in spermatogenesis","volume":"5","author":"Beumer","year":"1998","journal-title":"Cell Death Differ."},{"key":"10.1016\/j.dnarep.2018.08.027_bib0030","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1095\/biolreprod.102.008920","article-title":"Function of DNA-protein kinase catalytic subunit during the early meiotic prophase without Ku70 and Ku86","volume":"68","author":"Hamer","year":"2003","journal-title":"Biol. Reprod."},{"key":"10.1016\/j.dnarep.2018.08.027_bib0035","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1111\/j.1365-2605.2003.00436.x","article-title":"Intercellular bridges and apoptosis in clones of male germ cells","volume":"26","author":"Hamer","year":"2003","journal-title":"Int. J. Androl."},{"key":"10.1016\/j.dnarep.2018.08.027_bib0040","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1159\/000076812","article-title":"Specific arrests of spermatogenesis in genetically modified and mutant mice","volume":"103","author":"de Rooij","year":"2003","journal-title":"Cytogenet. Genome Res."},{"key":"10.1016\/j.dnarep.2018.08.027_bib0045","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1038\/nrg2505","article-title":"The consequences of asynapsis for mammalian meiosis","volume":"10","author":"Burgoyne","year":"2009","journal-title":"Nat. Rev. Genet."},{"key":"10.1016\/j.dnarep.2018.08.027_bib0050","doi-asserted-by":"crossref","first-page":"1180","DOI":"10.1016\/j.fertnstert.2013.08.010","article-title":"Effects of chemotherapy and radiotherapy on spermatogenesis in humans","volume":"100","author":"Meistrich","year":"2013","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.dnarep.2018.08.027_bib0055","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1093\/mutage\/ger017","article-title":"Kinetics of gamma-H2AX induction and removal in bone marrow and testicular cells of mice after X-ray irradiation","volume":"26","author":"Paris","year":"2011","journal-title":"Mutagenesis"},{"key":"10.1016\/j.dnarep.2018.08.027_bib0060","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/j.dnarep.2010.10.007","article-title":"Protecting the heritable genome: DNA damage response mechanisms in spermatogonial stem cells","volume":"10","author":"Rube","year":"2011","journal-title":"DNA Repair"},{"key":"10.1016\/j.dnarep.2018.08.027_bib0065","doi-asserted-by":"crossref","first-page":"433","DOI":"10.2307\/3574325","article-title":"Effect of 60Co gamma radiation on the stem and differentiating spermatogonia of the postpuberal rat","volume":"68","author":"Erickson","year":"1976","journal-title":"Radiat. Res."},{"key":"10.1016\/j.dnarep.2018.08.027_bib0070","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1002\/aja.1001280302","article-title":"Role of spermatogonia in the repair of the seminiferous epithelium following x-irradiation of the rat testis","volume":"128","author":"Dym","year":"1970","journal-title":"Am. J. Anat."},{"key":"10.1016\/j.dnarep.2018.08.027_bib0075","doi-asserted-by":"crossref","first-page":"296","DOI":"10.2307\/3578374","article-title":"The sensitivity to X rays of mouse spermatogonia that are committed to differentiate and of differentiating spermatogonia","volume":"130","author":"van der Meer","year":"1992","journal-title":"Radiat. Res."},{"key":"10.1016\/j.dnarep.2018.08.027_bib0080","first-page":"1","article-title":"Probability of self-renewing divisions of spermatogonial stem cells in colonies, formed after fission neutron irradiation","volume":"23","author":"van Beek","year":"1990","journal-title":"Cell Tissue Kinet."},{"key":"10.1016\/j.dnarep.2018.08.027_bib0085","doi-asserted-by":"crossref","first-page":"3929","DOI":"10.1172\/JCI75943","article-title":"PAX7 expression defines germline stem cells in the adult testis","volume":"124","author":"Aloisio","year":"2014","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.dnarep.2018.08.027_bib0090","doi-asserted-by":"crossref","first-page":"6175","DOI":"10.1038\/srep06175","article-title":"Bmi1 expression in long-term germ stem cells","volume":"4","author":"Komai","year":"2014","journal-title":"Sci. Rep."},{"key":"10.1016\/j.dnarep.2018.08.027_bib0095","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1002\/jemt.20730","article-title":"gammaH2AX marks the main events of the spermatogenic process","volume":"72","author":"Blanco-Rodriguez","year":"2009","journal-title":"Microsc. Res. Tech."},{"key":"10.1016\/j.dnarep.2018.08.027_bib0100","doi-asserted-by":"crossref","first-page":"628","DOI":"10.1095\/biolreprod.102.008672","article-title":"DNA double-strand breaks and gamma-H2AX signaling in the testis","volume":"68","author":"Hamer","year":"2003","journal-title":"Biol. Reprod."},{"key":"10.1016\/j.dnarep.2018.08.027_bib0105","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1080\/095530096144563","article-title":"P53 deficiency produces fewer regenerating spermatogenic tubules after irradiation","volume":"70","author":"Hendry","year":"1996","journal-title":"Int. J. Radiat. Biol."},{"key":"10.1016\/j.dnarep.2018.08.027_bib0110","doi-asserted-by":"crossref","first-page":"263","DOI":"10.2307\/3579959","article-title":"Resistance of differentiating spermatogonia to radiation-induced apoptosis and loss in p53-deficient mice","volume":"149","author":"Hasegawa","year":"1998","journal-title":"Radiat. Res."},{"key":"10.1016\/j.dnarep.2018.08.027_bib0115","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1016\/j.stemcr.2014.08.006","article-title":"The Trp53-Trp53inp1-Tnfrsf10b pathway regulates the radiation response of mouse spermatogonial stem cells","volume":"3","author":"Ishii","year":"2014","journal-title":"Stem Cell Rep."},{"key":"10.1016\/j.dnarep.2018.08.027_bib0120","doi-asserted-by":"crossref","first-page":"612","DOI":"10.1095\/biolreprod.103.017012","article-title":"Long-term proliferation in culture and germline transmission of mouse male germline stem cells","volume":"69","author":"Kanatsu-Shinohara","year":"2003","journal-title":"Biol. Reprod."},{"key":"10.1016\/j.dnarep.2018.08.027_bib0125","doi-asserted-by":"crossref","first-page":"4155","DOI":"10.1242\/dev.02004","article-title":"Genetic and epigenetic properties of mouse male germline stem cells during long-term culture","volume":"132","author":"Kanatsu-Shinohara","year":"2005","journal-title":"Development"},{"key":"10.1016\/j.dnarep.2018.08.027_bib0130","doi-asserted-by":"crossref","first-page":"2928","DOI":"10.1634\/stemcells.2008-0134","article-title":"Spermatogonial stem cell self-renewal requires OCT4, a factor downregulated during retinoic acid-induced differentiation","volume":"26","author":"Dann","year":"2008","journal-title":"Stem Cells"},{"key":"10.1016\/j.dnarep.2018.08.027_bib0135","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1016\/j.stemcr.2016.05.013","article-title":"Retinoic acid is sufficient for the in vitro induction of mouse spermatocytes","volume":"7","author":"Wang","year":"2016","journal-title":"Stem Cell Rep."},{"key":"10.1016\/j.dnarep.2018.08.027_bib0140","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1530\/REP-17-0173","article-title":"Trivial role for NSMCE2 during in vitro proliferation and differentiation of male germline stem cells","volume":"154","author":"Zheng","year":"2017","journal-title":"Reproduction"},{"key":"10.1016\/j.dnarep.2018.08.027_bib0145","doi-asserted-by":"crossref","first-page":"e749","DOI":"10.1038\/cddis.2013.269","article-title":"Role for rodent Smc6 in pericentromeric heterochromatin domains during spermatogonial differentiation and meiosis","volume":"4","author":"Verver","year":"2013","journal-title":"Cell Death Dis."},{"key":"10.1016\/j.dnarep.2018.08.027_bib0150","doi-asserted-by":"crossref","DOI":"10.3390\/ijms17111782","article-title":"Non-SMC element 2 (NSMCE2) of the SMC5\/6 complex helps to resolve topological stress","volume":"17","author":"Verver","year":"2016","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.dnarep.2018.08.027_bib0155","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1038\/nmeth.3317","article-title":"HISAT: a fast spliced aligner with low memory requirements","volume":"12","author":"Kim","year":"2015","journal-title":"Nat. Methods"},{"key":"10.1016\/j.dnarep.2018.08.027_bib0160","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1093\/bioinformatics\/btu638","article-title":"HTSeq--a Python framework to work with high-throughput sequencing data","volume":"31","author":"Anders","year":"2015","journal-title":"Bioinformatics"},{"key":"10.1016\/j.dnarep.2018.08.027_bib0165","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1093\/bioinformatics\/btp616","article-title":"edgeR: a Bioconductor package for differential expression analysis of digital gene expression data","volume":"26","author":"Robinson","year":"2010","journal-title":"Bioinformatics"},{"key":"10.1016\/j.dnarep.2018.08.027_bib0170","doi-asserted-by":"crossref","first-page":"e47","DOI":"10.1093\/nar\/gkv007","article-title":"Limma powers differential expression analyses for RNA-sequencing and microarray studies","volume":"43","author":"Ritchie","year":"2015","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.dnarep.2018.08.027_bib0175","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1038\/nprot.2008.211","article-title":"Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources","volume":"4","author":"Huang da","year":"2009","journal-title":"Nat. Protoc."},{"key":"10.1016\/j.dnarep.2018.08.027_bib0180","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1093\/nar\/gkn923","article-title":"Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists","volume":"37","author":"Huang da","year":"2009","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.dnarep.2018.08.027_bib0185","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1038\/ng1180","article-title":"PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes","volume":"34","author":"Mootha","year":"2003","journal-title":"Nat. Genet."},{"key":"10.1016\/j.dnarep.2018.08.027_bib0190","doi-asserted-by":"crossref","first-page":"15545","DOI":"10.1073\/pnas.0506580102","article-title":"Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles","volume":"102","author":"Subramanian","year":"2005","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.dnarep.2018.08.027_bib0195","doi-asserted-by":"crossref","first-page":"985","DOI":"10.1095\/biolreprod.104.036400","article-title":"Long-term culture of mouse male germline stem cells under serum-or feeder-free conditions","volume":"72","author":"Kanatsu-Shinohara","year":"2005","journal-title":"Biol. Reprod."},{"key":"10.1016\/j.dnarep.2018.08.027_bib0200","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1095\/biolreprod.107.064337","article-title":"Expression of stimulated by retinoic acid gene 8 (Stra8) and maturation of murine gonocytes and spermatogonia induced by retinoic acid in vitro","volume":"78","author":"Zhou","year":"2008","journal-title":"Biol. Reprod."},{"key":"10.1016\/j.dnarep.2018.08.027_bib0205","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1095\/biolreprod.107.066795","article-title":"Expression of stimulated by retinoic acid gene 8 (Stra8) in spermatogenic cells induced by retinoic acid: an in vivo study in vitamin A-sufficient postnatal murine testes","volume":"79","author":"Zhou","year":"2008","journal-title":"Biol. Reprod."},{"key":"10.1016\/j.dnarep.2018.08.027_bib0210","doi-asserted-by":"crossref","first-page":"1248012","DOI":"10.1126\/science.1248012","article-title":"Stem cell signaling. An integral program for tissue renewal and regeneration: wnt signaling and stem cell control","volume":"346","author":"Clevers","year":"2014","journal-title":"Science"},{"key":"10.1016\/j.dnarep.2018.08.027_bib0215","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1530\/REP-08-0510","article-title":"Wnt signaling promotes proliferation and stemness regulation of spermatogonial stem\/progenitor cells","volume":"138","author":"Golestaneh","year":"2009","journal-title":"Reproduction"},{"key":"10.1016\/j.dnarep.2018.08.027_bib0220","doi-asserted-by":"crossref","first-page":"1981","DOI":"10.3892\/mmr.2017.6240","article-title":"Slit2 suppresses endothelial cell proliferation and migration by inhibiting the VEGF-Notch signaling pathway","volume":"15","author":"Li","year":"2017","journal-title":"Mol. Med. Rep."},{"key":"10.1016\/j.dnarep.2018.08.027_bib0225","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1016\/j.cmet.2013.12.002","article-title":"Pdx1 maintains beta cell identity and function by repressing an alpha cell program","volume":"19","author":"Gao","year":"2014","journal-title":"Cell Metab."},{"key":"10.1016\/j.dnarep.2018.08.027_bib0230","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.resp.2015.11.005","article-title":"The in vivo respiratory phenotype of the adenosine A1 receptor knockout mouse","volume":"222","author":"Heitzmann","year":"2016","journal-title":"Respir. Physiol. Neurobiol."},{"key":"10.1016\/j.dnarep.2018.08.027_bib0235","doi-asserted-by":"crossref","first-page":"1610","DOI":"10.1007\/s00125-015-3570-3","article-title":"Abrogation of adenosine A1 receptor signalling improves metabolic regulation in mice by modulating oxidative stress and inflammatory responses","volume":"58","author":"Yang","year":"2015","journal-title":"Diabetologia"},{"key":"10.1016\/j.dnarep.2018.08.027_bib0240","doi-asserted-by":"crossref","first-page":"4077","DOI":"10.1242\/jcs.00739","article-title":"Apoptosis - the p53 network","volume":"116","author":"Haupt","year":"2003","journal-title":"J. Cell Sci."},{"key":"10.1016\/j.dnarep.2018.08.027_bib0245","doi-asserted-by":"crossref","first-page":"6936","DOI":"10.1128\/MCB.23.19.6936-6943.2003","article-title":"Role of Plk2 (Snk) in mouse development and cell proliferation","volume":"23","author":"Ma","year":"2003","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.dnarep.2018.08.027_bib0250","doi-asserted-by":"crossref","first-page":"7247","DOI":"10.1038\/sj.onc.1207010","article-title":"Cloning and characterization of a novel gene PDRG that is differentially regulated by p53 and ultraviolet radiation","volume":"22","author":"Luo","year":"2003","journal-title":"Oncogene"},{"key":"10.1016\/j.dnarep.2018.08.027_bib0255","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.yexcr.2017.03.023","article-title":"Sestrin 2 induces autophagy and attenuates insulin resistance by regulating AMPK signaling in C2C12 myotubes","volume":"354","author":"Li","year":"2017","journal-title":"Exp. Cell Res."},{"key":"10.1016\/j.dnarep.2018.08.027_bib0260","doi-asserted-by":"crossref","first-page":"742","DOI":"10.1095\/biolreprod.110.085456","article-title":"BMP4-induced differentiation of a rat spermatogonial stem cell line causes changes in its cell adhesion properties","volume":"83","author":"Carlomagno","year":"2010","journal-title":"Biol. Reprod."},{"key":"10.1016\/j.dnarep.2018.08.027_bib0265","doi-asserted-by":"crossref","DOI":"10.1155\/2016\/9536192","article-title":"BMP4 cooperates with retinoic acid to induce the expression of differentiation markers in cultured mouse spermatogonia","author":"Yang","year":"2016","journal-title":"Stem Cells Int."},{"key":"10.1016\/j.dnarep.2018.08.027_bib0270","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1095\/biolreprod.115.135145","article-title":"The role of retinoic acid (RA) in spermatogonial differentiation","volume":"94","author":"Busada","year":"2016","journal-title":"Biol. Reprod."},{"key":"10.1016\/j.dnarep.2018.08.027_bib0275","doi-asserted-by":"crossref","first-page":"e0140260","DOI":"10.1371\/journal.pone.0140260","article-title":"Wnt16 Is Associated with Age-Related Bone Loss and Estrogen Withdrawal in Murine Bone","volume":"10","author":"Todd","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.dnarep.2018.08.027_bib0280","doi-asserted-by":"crossref","first-page":"1023","DOI":"10.1210\/en.2014-1702","article-title":"Role of WNT16 in the regulation of periosteal bone formation in female mice","volume":"156","author":"Wergedal","year":"2015","journal-title":"Endocrinology"},{"key":"10.1016\/j.dnarep.2018.08.027_bib0285","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1007\/s00018-004-4394-y","article-title":"Gene expression in spermiogenesis","volume":"62","author":"Tanaka","year":"2005","journal-title":"Cell Mol. Life Sci. CMLS"},{"key":"10.1016\/j.dnarep.2018.08.027_bib0290","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1530\/REP-09-0163","article-title":"Expression pattern of meiosis associated SYCP family members during germline development in chickens","volume":"138","author":"Zheng","year":"2009","journal-title":"Reproduction"},{"key":"10.1016\/j.dnarep.2018.08.027_bib0295","doi-asserted-by":"crossref","first-page":"3233","DOI":"10.1093\/humrep\/des301","article-title":"Global human tissue profiling and protein network analysis reveals distinct levels of transcriptional germline-specificity and identifies target genes for male infertility","volume":"27","author":"Chalmel","year":"2012","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.dnarep.2018.08.027_bib0300","doi-asserted-by":"crossref","first-page":"3659","DOI":"10.1242\/dev.152413","article-title":"Unraveling transcriptome dynamics in human spermatogenesis","volume":"144","author":"Jan","year":"2017","journal-title":"Development"},{"key":"10.1016\/j.dnarep.2018.08.027_bib0305","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1002\/aja.1000990307","article-title":"Duration of spermatogenesis in the mouse and timing of stages of the cycle of the seminiferous epithelium","volume":"99","author":"Oakberg","year":"1956","journal-title":"Am. J. Anat."},{"key":"10.1016\/j.dnarep.2018.08.027_bib0310","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1002\/aja.1001110202","article-title":"Quantitative analysis of spermatogenesis of the rat: a revised model for the renewal of spermatogonia","volume":"111","author":"Clermont","year":"1962","journal-title":"Am. J. Anat."},{"key":"10.1016\/j.dnarep.2018.08.027_bib0315","doi-asserted-by":"crossref","first-page":"14976","DOI":"10.1073\/pnas.0807297105","article-title":"Stra8 and its inducer, retinoic acid, regulate meiotic initiation in both spermatogenesis and oogenesis in mice","volume":"105","author":"Anderson","year":"2008","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.dnarep.2018.08.027_bib0320","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1016\/j.stemcr.2016.12.006","article-title":"Mesenchymal to epithelial transition mediated by CDH1 promotes spontaneous reprogramming of male germline stem cells to pluripotency","volume":"8","author":"An","year":"2017","journal-title":"Stem Cell Rep."},{"key":"10.1016\/j.dnarep.2018.08.027_bib0325","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1095\/biolreprod.106.053181","article-title":"CDH1 is a specific marker for undifferentiated spermatogonia in mouse testes","volume":"76","author":"Tokuda","year":"2007","journal-title":"Biol. Reprod."},{"key":"10.1016\/j.dnarep.2018.08.027_bib0330","doi-asserted-by":"crossref","first-page":"6487","DOI":"10.1073\/pnas.0631767100","article-title":"Spermatogonial stem cells share some, but not all, phenotypic and functional characteristics with other stem cells","volume":"100","author":"Kubota","year":"2003","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.dnarep.2018.08.027_bib0335","doi-asserted-by":"crossref","first-page":"2312","DOI":"10.1101\/gad.261925.115","article-title":"Transcription and imprinting dynamics in developing postnatal male germline stem cells","volume":"29","author":"Hammoud","year":"2015","journal-title":"Genes Dev."},{"key":"10.1016\/j.dnarep.2018.08.027_bib0340","doi-asserted-by":"crossref","first-page":"a000935","DOI":"10.1101\/cshperspect.a000935","article-title":"Transcriptional regulation by p53","volume":"2","author":"Beckerman","year":"2010","journal-title":"Cold Spring Harb. Perspect. Biol."},{"key":"10.1016\/j.dnarep.2018.08.027_bib0345","first-page":"393","article-title":"p53 in survival, death and metabolic health: a lifeguard with a licence to kill, nature reviews","volume":"16","author":"Kruiswijk","year":"2015","journal-title":"Mol. Cell Biol."},{"key":"10.1016\/j.dnarep.2018.08.027_bib0350","first-page":"4239","article-title":"Dynamic localization of SMC5\/6 complex proteins during mammalian meiosis and mitosis suggests functions in distinct chromosome processes","volume":"126","author":"Gomez","year":"2013","journal-title":"J. Cell Sci."},{"key":"10.1016\/j.dnarep.2018.08.027_bib0355","doi-asserted-by":"crossref","first-page":"1562","DOI":"10.1242\/dev.108258","article-title":"Plk2 regulates mitotic spindle orientation and mammary gland development","volume":"141","author":"Villegas","year":"2014","journal-title":"Development"},{"key":"10.1016\/j.dnarep.2018.08.027_bib0360","first-page":"5061","article-title":"Polo-like kinase is required for synaptonemal complex disassembly and phosphorylation in mouse spermatocytes","volume":"125","author":"Jordan","year":"2012","journal-title":"J. Cell Sci."},{"key":"10.1016\/j.dnarep.2018.08.027_bib0365","doi-asserted-by":"crossref","first-page":"567","DOI":"10.4161\/cbt.11.6.14412","article-title":"PDRG1, a novel tumor marker for multiple malignancies that is selectively regulated by genotoxic stress","volume":"11","author":"Jiang","year":"2011","journal-title":"Cancer Biol. Ther."}],"container-title":["DNA Repair"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1568786418300636?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1568786418300636?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T20:41:27Z","timestamp":1761597687000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1568786418300636"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,10]]},"references-count":73,"alternative-id":["S1568786418300636"],"URL":"https:\/\/doi.org\/10.1016\/j.dnarep.2018.08.027","relation":{},"ISSN":["1568-7864"],"issn-type":[{"value":"1568-7864","type":"print"}],"subject":[],"published":{"date-parts":[[2018,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The influence of retinoic acid-induced differentiation on the radiation response of male germline stem cells","name":"articletitle","label":"Article Title"},{"value":"DNA Repair","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.dnarep.2018.08.027","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}