{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,11]],"date-time":"2026-03-11T08:47:08Z","timestamp":1773218828214,"version":"3.50.1"},"reference-count":58,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T00:00:00Z","timestamp":1646092800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T00:00:00Z","timestamp":1646092800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T00:00:00Z","timestamp":1646092800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T00:00:00Z","timestamp":1646092800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T00:00:00Z","timestamp":1646092800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T00:00:00Z","timestamp":1646092800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T00:00:00Z","timestamp":1646092800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["JP 16H02956"],"award-info":[{"award-number":["JP 16H02956"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["JP 17K12824"],"award-info":[{"award-number":["JP 17K12824"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["JP 19H04278"],"award-info":[{"award-number":["JP 19H04278"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["JP 20K12181"],"award-info":[{"award-number":["JP 20K12181"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["DNA Repair"],"published-print":{"date-parts":[[2022,3]]},"DOI":"10.1016\/j.dnarep.2022.103276","type":"journal-article","created":{"date-parts":[[2022,1,22]],"date-time":"2022-01-22T02:59:38Z","timestamp":1642820378000},"page":"103276","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":16,"special_numbering":"C","title":["Paradoxical role of the major DNA repair protein, OGG1, in action-at-a-distance mutation induction by 8-oxo-7,8-dihydroguanine"],"prefix":"10.1016","volume":"111","author":[{"given":"Tetsuya","family":"Suzuki","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yudai","family":"Zaima","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshihiro","family":"Fujikawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ruriko","family":"Fukushima","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroyuki","family":"Kamiya","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.dnarep.2022.103276_bib1","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/0014-5793(91)80347-6","article-title":"DNA damage by oxygen-derived species. Its mechanism and measurement in mammalian systems","volume":"281","author":"Halliwell","year":"1991","journal-title":"FEBS Lett."},{"key":"10.1016\/j.dnarep.2022.103276_bib2","doi-asserted-by":"crossref","first-page":"7915","DOI":"10.1073\/pnas.90.17.7915","article-title":"Oxidants, antioxidants, and the degenerative diseases of aging","volume":"90","author":"Ames","year":"1993","journal-title":"Proc. Natl. Acad. Sci. U. S. A"},{"key":"10.1016\/j.dnarep.2022.103276_bib3","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/S0027-5107(01)00091-4","article-title":"The contribution of endogenous sources of DNA damage to the multiple mutations in cancer","volume":"477","author":"Jackson","year":"2001","journal-title":"Mutat. Res."},{"key":"10.1016\/j.dnarep.2022.103276_bib4","doi-asserted-by":"crossref","first-page":"2137","DOI":"10.1093\/nar\/12.4.2137","article-title":"Hydroxylation of deoxyguanosine at the C-8 position by ascorbic acid and other reducing agents","volume":"12","author":"Kasai","year":"1984","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.dnarep.2022.103276_bib5","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1038\/362709a0","article-title":"Instability and decay of the primary structure of DNA","volume":"362","author":"Lindahl","year":"1993","journal-title":"Nature"},{"key":"10.1016\/j.dnarep.2022.103276_bib6","doi-asserted-by":"crossref","first-page":"1407","DOI":"10.1093\/nar\/19.7.1407","article-title":"NMR studies of a DNA containing 8-hydroxydeoxyguanosine","volume":"19","author":"Oda","year":"1991","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.dnarep.2022.103276_bib7","doi-asserted-by":"crossref","first-page":"1403","DOI":"10.1021\/bi00219a034","article-title":"NMR structural studies of the ionizing radiation adduct 7-hydro-8-oxodeoxyguanosine (8-oxo-7H-dG) opposite deoxyadenosine in a DNA duplex. 8-Oxo-7H-dG(syn)\u2022dA(anti) alignment at lesion site","volume":"30","author":"Kouchakdjian","year":"1991","journal-title":"Biochemistry"},{"key":"10.1016\/j.dnarep.2022.103276_bib8","doi-asserted-by":"crossref","first-page":"1517","DOI":"10.1080\/15257779408012168","article-title":"Synthesis and thermodynamic stabilities of damaged DNA involving 8-hydroxyguanine (7,8-dihydro-8-oxoguanine) in a ras gene fragment","volume":"13","author":"Koizume","year":"1994","journal-title":"Nucleosides Nucleotides"},{"key":"10.1016\/j.dnarep.2022.103276_bib9","doi-asserted-by":"crossref","first-page":"16148","DOI":"10.1021\/bi00049a030","article-title":"Influence of the oxidatively damaged adduct 8-oxodeoxyguanosine on the conformation, energetics, and thermodynamic stability of a DNA duplex","volume":"34","author":"Plum","year":"1995","journal-title":"Biochemistry"},{"key":"10.1016\/j.dnarep.2022.103276_bib10","first-page":"3483","article-title":"c-Ha-ras containing 8-hydroxyguanine at codon 12 induces point mutations at the modified and adjacent positions","volume":"52","author":"Kamiya","year":"1992","journal-title":"Cancer Res."},{"key":"10.1016\/j.dnarep.2022.103276_bib11","doi-asserted-by":"crossref","first-page":"1122","DOI":"10.1073\/pnas.90.3.1122","article-title":"Single-stranded shuttle phagemid for mutagenesis studies in mammalian cells: 8-oxoguanine in DNA induces targeted G\u2022C\u2192T\u2022A transversions in simian kidney cells","volume":"90","author":"Moriya","year":"1993","journal-title":"Proc. Natl. Acad. Sci. U. S. A"},{"key":"10.1016\/j.dnarep.2022.103276_bib12","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1093\/carcin\/16.4.883","article-title":"8-Hydroxyguanine (7,8-dihydro-8-oxoguanine) in hot spots of the c-Ha-ras gene. Effects of sequence contexts on mutation spectra","volume":"16","author":"Kamiya","year":"1995","journal-title":"Carcinogenesis"},{"key":"10.1016\/j.dnarep.2022.103276_bib13","doi-asserted-by":"crossref","first-page":"2779","DOI":"10.1093\/carcin\/16.11.2779","article-title":"Mutagenicity of a unique 8-oxoguanine in a human Ha-ras sequence in mammalian cells","volume":"16","author":"Le Page","year":"1995","journal-title":"Carcinogenesis"},{"key":"10.1016\/j.dnarep.2022.103276_bib14","doi-asserted-by":"crossref","first-page":"2287","DOI":"10.1093\/carcin\/20.12.2287","article-title":"Comparison of the mutagenic properties of 8-oxo-7,8-dihydro-2\u2032-deoxyadenosine and 8-oxo-7,8-dihydro-2\u2032-deoxyguanosine DNA lesions in mammalian cells","volume":"20","author":"Tan","year":"1999","journal-title":"Carcinogenesis"},{"key":"10.1016\/j.dnarep.2022.103276_bib15","doi-asserted-by":"crossref","first-page":"1552","DOI":"10.1016\/j.freeradbiomed.2007.02.024","article-title":"Mutagenic effects of 8-hydroxy-dGTP in live mammalian cells","volume":"42","author":"Satou","year":"2007","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.dnarep.2022.103276_bib16","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1016\/j.dnarep.2008.12.009","article-title":"Involvement of specialized DNA polymerases in mutagenesis by 8-hydroxy-dGTP in human cells","volume":"8","author":"Satou","year":"2009","journal-title":"DNA Repair"},{"key":"10.1016\/j.dnarep.2022.103276_bib17","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1093\/nar\/gkg137","article-title":"Mutagenic potentials of damaged nucleic acids produced by reactive oxygen\/nitrogen species: approaches using synthetic oligonucleotides and nucleotides","volume":"31","author":"Kamiya","year":"2003","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.dnarep.2022.103276_bib18","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1186\/s41021-016-0051-y","article-title":"Mutations induced by 8-hydroxyguanine (8-oxo-7,8-dihydroguanine), a representative oxidized base, in mammalian cells","volume":"39","author":"Suzuki","year":"2017","journal-title":"Genes Environ."},{"key":"10.1016\/j.dnarep.2022.103276_bib19","doi-asserted-by":"crossref","first-page":"1197","DOI":"10.1016\/j.freeradbiomed.2010.02.002","article-title":"Suppression of mutagenesis by 8-hydroxy-2\u2032-deoxyguanosine 5\u2032-triphosphate (7,8-dihydro-8-oxo-2\u2032-deoxyguanosine 5\u2032-triphosphate) by human MTH1, MTH2, and NUDT5","volume":"48","author":"Hori","year":"2010","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.dnarep.2022.103276_bib20","doi-asserted-by":"crossref","first-page":"6314","DOI":"10.1093\/emboj\/16.20.6314","article-title":"Opposite base-dependent reactions of a human base excision repair enzyme on DNA containing 7,8-dihydro-8-oxoguanine and abasic sites","volume":"16","author":"Bjoras","year":"1997","journal-title":"EMBO J."},{"key":"10.1016\/j.dnarep.2022.103276_bib21","first-page":"2151","article-title":"Cloning and characterization of mammalian 8-hydroxyguanine-specific DNA glycosylase\/apurinic, apyrimidinic lyase, a functional mutM homologue","volume":"57","author":"Aburatani","year":"1997","journal-title":"Cancer Res."},{"key":"10.1016\/j.dnarep.2022.103276_bib22","doi-asserted-by":"crossref","first-page":"7429","DOI":"10.1073\/pnas.94.14.7429","article-title":"Cloning and characterization of a mammalian 8-oxoguanine DNA glycosylase","volume":"94","author":"Rosenquist","year":"1997","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.dnarep.2022.103276_bib23","doi-asserted-by":"crossref","first-page":"8010","DOI":"10.1073\/pnas.94.15.8010","article-title":"Cloning and characterization of hOGG1, a human homolog of the OGG1 gene of Saccharomyces cerevisiae","volume":"94","author":"Radicella","year":"1997","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.dnarep.2022.103276_bib24","doi-asserted-by":"crossref","first-page":"8016","DOI":"10.1073\/pnas.94.15.8016","article-title":"Molecular cloning and functional expression of a human cDNA encoding the antimutator enzyme 8-hydroxyguanine-DNA glycosylase","volume":"94","author":"Rold\u00e1n-Arjona","year":"1997","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.dnarep.2022.103276_bib25","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1016\/S0960-9822(06)00187-4","article-title":"A mammalian DNA repair enzyme that excises oxidatively damaged guanines maps to a locus frequently lost in lung cancer","volume":"7","author":"Lu","year":"1997","journal-title":"Curr. Biol."},{"key":"10.1016\/j.dnarep.2022.103276_bib26","doi-asserted-by":"crossref","first-page":"2857","DOI":"10.1038\/sj.onc.1201139","article-title":"sCloning of a human homolog of the yeast OGG1 gene that is involved in the repair of oxidative DNA damage","volume":"14","author":"Arai","year":"1997","journal-title":"Oncogene"},{"key":"10.1016\/j.dnarep.2022.103276_bib27","doi-asserted-by":"crossref","first-page":"1355","DOI":"10.1093\/carcin\/22.9.1355","article-title":"OGG1 protein suppresses G:C\u2192T:A mutation in a shuttle vector containing 8-hydroxyguanine in human cells","volume":"22","author":"Sunaga","year":"2001","journal-title":"Carcinogenesis"},{"key":"10.1016\/j.dnarep.2022.103276_bib28","doi-asserted-by":"crossref","first-page":"542","DOI":"10.1016\/j.dnarep.2010.02.004","article-title":"Effects of base excision repair proteins on mutagenesis by 8-oxo-7,8-dihydroguanine (8-hydroxyguanine) paired with cytosine and adenine","volume":"9","author":"Suzuki","year":"2010","journal-title":"DNA Repair"},{"key":"10.1016\/j.dnarep.2022.103276_bib29","doi-asserted-by":"crossref","first-page":"3638","DOI":"10.1093\/nar\/27.18.3638","article-title":"Differential subcellular localization of human MutY homolog (hMYH) and the functional activity of adenine:8-oxoguanine DNA glycosylase","volume":"27","author":"Takao","year":"1999","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.dnarep.2022.103276_bib30","doi-asserted-by":"crossref","first-page":"6210","DOI":"10.1128\/JB.181.19.6210-6213.1999","article-title":"Functional expression of hMYH, a human homolog of the Escherichia coli MutY protein","volume":"181","author":"Slupska","year":"1999","journal-title":"J. Bacteriol."},{"key":"10.1016\/j.dnarep.2022.103276_bib31","doi-asserted-by":"crossref","first-page":"989","DOI":"10.1128\/MCB.15.2.989","article-title":"Characterization of a mammalian homolog of the Escherichia coli MutY mismatch repair protein","volume":"15","author":"McGoldrick","year":"1995","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.dnarep.2022.103276_bib32","doi-asserted-by":"crossref","first-page":"4542","DOI":"10.3390\/ijms22094542","article-title":"NEIL1 and NEIL2 are recruited as potential backup for OGG1 upon OGG1 depletion or inhibition by TH5487","volume":"22","author":"Hanna","year":"2021","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.dnarep.2022.103276_bib33","doi-asserted-by":"crossref","first-page":"4956","DOI":"10.1074\/jbc.275.7.4956","article-title":"Distinct repair activities of human 7,8-dihydro-8-oxoguanine DNA glycosylase and formamidopyrimidine DNA glycosylase for formamidopyrimidine and 7,8-dihydro-8-oxoguanine","volume":"275","author":"Asagoshi","year":"2000","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.dnarep.2022.103276_bib34","doi-asserted-by":"crossref","first-page":"11450","DOI":"10.1073\/pnas.88.24.11450","article-title":"Cloning and expression of APE, the cDNA encoding the major human apurinic endonuclease: Definition of a family of DNA repair enzymes","volume":"88","author":"Demple","year":"1991","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.dnarep.2022.103276_bib35","doi-asserted-by":"crossref","first-page":"5519","DOI":"10.1093\/nar\/19.20.5519","article-title":"Isolation of cDNA clones encoding a human apurinic\/apyrimidinic endonuclease that corrects DNA repair and mutagenesis defects in E. coli xth (exonuclease III) mutants","volume":"19","author":"Robson","year":"1991","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.dnarep.2022.103276_bib36","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/0167-4781(92)90027-W","article-title":"cDNA cloning, sequencing, expression and possible domain structure of human APEX nuclease homologous to Escherichia coli exonuclease III","volume":"1131","author":"Seki","year":"1992","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.dnarep.2022.103276_bib37","doi-asserted-by":"crossref","first-page":"3323","DOI":"10.1002\/j.1460-2075.1992.tb05411.x","article-title":"Redox activation of Fos-Jun DNA binding activity is mediated by a DNA repair enzyme","volume":"11","author":"Xanthoudakis","year":"1992","journal-title":"EMBO J."},{"key":"10.1016\/j.dnarep.2022.103276_bib38","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1146\/annurev.genet.38.072902.092448","article-title":"Repair and genetic consequences of endogenous DNA base damage in mammalian cells","volume":"38","author":"Barnes","year":"2004","journal-title":"Annu. Rev. Genet."},{"key":"10.1016\/j.dnarep.2022.103276_bib39","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1186\/s41021-020-00153-3","article-title":"High-throughput analysis of DNA repair in microplates towards identification of inhibitors","volume":"42","author":"Kamiya","year":"2020","journal-title":"Genes Environ."},{"key":"10.1016\/j.dnarep.2022.103276_bib40","doi-asserted-by":"crossref","first-page":"15230","DOI":"10.1074\/jbc.274.21.15230","article-title":"The type of DNA glycosylase determines the base excision repair pathway in mammalian cells","volume":"274","author":"Fortini","year":"1999","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.dnarep.2022.103276_bib41","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1021\/tx500418m","article-title":"Action-at-a-distance mutagenesis induced by oxidized guanine in Werner syndrome protein-reduced human cells","volume":"28","author":"Kamiya","year":"2015","journal-title":"Chem. Res. Toxicol."},{"key":"10.1016\/j.dnarep.2022.103276_bib42","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1093\/mutage\/geab027","article-title":"Action-at-a-distance mutations at 5\u2032-GpA-3\u2032 sites induced by oxidised guanine in WRN-knockdown cells","volume":"36","author":"Suzuki","year":"2021","journal-title":"Mutagenesis"},{"key":"10.1016\/j.dnarep.2022.103276_bib43","doi-asserted-by":"crossref","first-page":"2615","DOI":"10.1038\/bjc.2014.176","article-title":"Erroneous identification of APOBEC3-edited chromosomal DNA in cancer genomics","volume":"110","author":"Susp\u00e8ne","year":"2014","journal-title":"Br. J. Cancer"},{"key":"10.1016\/j.dnarep.2022.103276_bib44","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1038\/nature12477","article-title":"Signatures of mutational processes in human cancer","volume":"500","author":"Alexandrov","year":"2013","journal-title":"Nature"},{"key":"10.1016\/j.dnarep.2022.103276_bib45","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.02001","article-title":"Repair of naturally occurring mismatches can induce mutations in flanking DNA","volume":"3","author":"Chen","year":"2014","journal-title":"eLife"},{"key":"10.1016\/j.dnarep.2022.103276_bib46","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1269\/jrr.39.263","article-title":"An improved system for selection of forward mutations in an Escherichia coli supF gene carried by plasmids","volume":"39","author":"Obata","year":"1998","journal-title":"J. Radiat. Res."},{"key":"10.1016\/j.dnarep.2022.103276_bib47","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1186\/s41021-020-00167-x","article-title":"New indicator Escherichia coli strain for rapid and accurate detection of supF mutations","volume":"42","author":"Fukushima","year":"2020","journal-title":"Genes Environ."},{"key":"10.1016\/j.dnarep.2022.103276_bib48","doi-asserted-by":"crossref","first-page":"6640","DOI":"10.1073\/pnas.120163297","article-title":"One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products","volume":"97","author":"Datsenko","year":"2000","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.dnarep.2022.103276_bib49","first-page":"421","article-title":"Large deletions and untargeted substitutions induced by abasic site analog on leading versus lagging strand templates in human cells","volume":"34","author":"Suzuki","year":"2019","journal-title":"Mutagenesis"},{"key":"10.1016\/j.dnarep.2022.103276_bib50","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0115318","article-title":"Hot Fusion: an efficient method to clone multiple DNA fragments as well as inverted repeats without ligase","volume":"9","author":"Fu","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.dnarep.2022.103276_bib51","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1016\/j.mrfmmm.2010.02.001","article-title":"Roles of specialized DNA polymerases in mutagenesis by 8-hydroxyguanine in human cells","volume":"686","author":"Kamiya","year":"2010","journal-title":"Mutat. Res."},{"key":"10.1016\/j.dnarep.2022.103276_bib52","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1093\/nar\/25.2.304","article-title":"Substitution and deletion mutations induced by 2-hydroxyadenine in Escherichia coli: effects of sequence contexts in leading and lagging strands","volume":"25","author":"Kamiya","year":"1997","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.dnarep.2022.103276_bib53","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1016\/j.dnarep.2004.01.003","article-title":"Effect of 8-oxoguanine on transcription elongation by T7 RNA polymerase and mammalian RNA polymerase II","volume":"3","author":"Tornaletti","year":"2004","journal-title":"DNA Repair"},{"key":"10.1016\/j.dnarep.2022.103276_bib54","doi-asserted-by":"crossref","first-page":"103","DOI":"10.3123\/jemsge.33.103","article-title":"Unexpectedly weak impacts of decreased p53 and retinoblastoma protein levels on mutagenesis by 8-oxo-7,8-dihydroguanine (8-hydroxyguanine)","volume":"33","author":"Suzuki","year":"2011","journal-title":"Genes Environ."},{"key":"10.1016\/j.dnarep.2022.103276_bib55","doi-asserted-by":"crossref","first-page":"283","DOI":"10.2131\/jts.46.283","article-title":"Similar frequency and signature of untargeted substitutions induced by abasic site analog under reduced human APE1 conditions","volume":"46","author":"Suzuki","year":"2021","journal-title":"J. Toxicol. Sci."},{"key":"10.1016\/j.dnarep.2022.103276_bib56","doi-asserted-by":"crossref","first-page":"1679","DOI":"10.1099\/0022-1317-73-7-1679","article-title":"Simian virus 40 (SV40) large T antigen-dependent amplification of an Epstein-Barr virus-SV40 hybrid shuttle vector integrated into the human HeLa cell genome","volume":"73","author":"Stary","year":"1992","journal-title":"J. Gen. Virol."},{"key":"10.1016\/j.dnarep.2022.103276_bib57","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1038\/nmeth.2089","article-title":"NIH Image to ImageJ: 25 years of image analysis","volume":"9","author":"Schneider","year":"2012","journal-title":"Nat. Methods"},{"key":"10.1016\/j.dnarep.2022.103276_bib58","doi-asserted-by":"crossref","first-page":"10017","DOI":"10.1074\/jbc.M110.176636","article-title":"Non-B DNA-forming sequences and WRN deficiency independently increase the frequency of base substitution in human cells","volume":"286","author":"Bacolla","year":"2011","journal-title":"J. Biol. Chem."}],"container-title":["DNA Repair"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1568786422000052?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1568786422000052?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T20:49:08Z","timestamp":1761598148000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1568786422000052"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,3]]},"references-count":58,"alternative-id":["S1568786422000052"],"URL":"https:\/\/doi.org\/10.1016\/j.dnarep.2022.103276","relation":{},"ISSN":["1568-7864"],"issn-type":[{"value":"1568-7864","type":"print"}],"subject":[],"published":{"date-parts":[[2022,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Paradoxical role of the major DNA repair protein, OGG1, in action-at-a-distance mutation induction by 8-oxo-7,8-dihydroguanine","name":"articletitle","label":"Article Title"},{"value":"DNA Repair","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.dnarep.2022.103276","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"103276"}}