{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,25]],"date-time":"2026-02-25T06:01:10Z","timestamp":1771999270622,"version":"3.50.1"},"reference-count":30,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2007,1,1]],"date-time":"2007-01-01T00:00:00Z","timestamp":1167609600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Domestic Animal Endocrinology"],"published-print":{"date-parts":[[2007,1]]},"DOI":"10.1016\/j.domaniend.2005.12.009","type":"journal-article","created":{"date-parts":[[2006,1,31]],"date-time":"2006-01-31T12:39:07Z","timestamp":1138711147000},"page":"43-54","source":"Crossref","is-referenced-by-count":30,"title":["Acromegaly due to a somatroph adenoma in a dog"],"prefix":"10.1016","volume":"32","author":[{"given":"F.","family":"Fracassi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Gandini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Diana","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Preziosi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.S.G.A.M. van den","family":"Ingh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Famigli-Bergamini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.S.","family":"Kooistra","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.domaniend.2005.12.009_bib1","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1111\/j.1939-1676.1990.tb00897.x","article-title":"Acromegaly in 14 cats","volume":"4","author":"Peterson","year":"1990","journal-title":"J Vet Intern Med"},{"key":"10.1016\/j.domaniend.2005.12.009_bib2","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1016\/S1096-6374(03)00076-5","article-title":"Endocrine diseases in dogs and cats: similarities and differences with endocrine diseases in humans","volume":"13","author":"Rijnberk","year":"2003","journal-title":"GH IGF Res"},{"key":"10.1016\/j.domaniend.2005.12.009_bib3","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1210\/en.134.1.287","article-title":"Progestin-induced growth hormone excess in the dog originates in the mammary gland","volume":"134","author":"Selman","year":"1994","journal-title":"Endocrinology"},{"key":"10.1016\/j.domaniend.2005.12.009_bib4","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1530\/acta.0.1040167","article-title":"Progesterone-controlled growth hormone overproduction and naturally occurring canine diabetes and acromegaly","volume":"104","author":"Eigenmann","year":"1983","journal-title":"Acta Endocrinol"},{"key":"10.1016\/j.domaniend.2005.12.009_bib5","series-title":"Textbook of Veterinary Internal Medicine","first-page":"1498","article-title":"Acromegaly and pituitary dwarfism","author":"Kooistra","year":"2005"},{"key":"10.1016\/j.domaniend.2005.12.009_bib6","first-page":"1","article-title":"\u00dcber Hypophysentumoren beim Hunde","volume":"3","author":"Lucksch","year":"1923","journal-title":"Tier\u00e4rztl Arch"},{"key":"10.1016\/j.domaniend.2005.12.009_bib7","first-page":"133","article-title":"Diabetes mellitus with pituitary neoplasms in a horse and in a dog","volume":"52","author":"King","year":"1962","journal-title":"Cornell Vet"},{"key":"10.1016\/j.domaniend.2005.12.009_bib8","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1177\/030098589603300417","article-title":"Diabetes mellitus in a dog with a growth hormone-producing acidophilic adenoma of the adenohypophysis","volume":"33","author":"van Keulen LJM","year":"1996","journal-title":"Vet Pathol"},{"key":"10.1016\/j.domaniend.2005.12.009_bib9","doi-asserted-by":"crossref","first-page":"1507","DOI":"10.1136\/bmj.1.5291.1507","article-title":"Intravenous glucose tolerance as a tool in definition and diagnosis of diabetes mellitus","volume":"1","author":"Lundb\u01fdk","year":"1962","journal-title":"Br Med J"},{"key":"10.1016\/j.domaniend.2005.12.009_bib10","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1530\/acta.0.0980514","article-title":"Radioimmunoassay of canine growth hormone","volume":"98","author":"Eigenmann","year":"1981","journal-title":"Acta Endocrinol"},{"key":"10.1016\/j.domaniend.2005.12.009_bib11","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1089\/152091599317017","article-title":"Comparison of a radioimmunoassay with a microparticle enzyme immunoassay of insulin for use with the minimal model method of determining whole-body insulin sensitivity","volume":"1","author":"Rood","year":"1999","journal-title":"Diabetes Technol Ther"},{"key":"10.1016\/j.domaniend.2005.12.009_bib12","doi-asserted-by":"crossref","first-page":"1625","DOI":"10.2460\/ajvr.2004.65.1625","article-title":"High-frequency ultrasonography of the skin of clinically normal dogs","volume":"65","author":"Diana","year":"2004","journal-title":"Am J Vet Res"},{"key":"10.1016\/j.domaniend.2005.12.009_bib13","first-page":"1109","article-title":"Acromegaly: a review of 100 cases","volume":"87","author":"Gordon","year":"1962","journal-title":"Can Med Assoc J"},{"key":"10.1016\/j.domaniend.2005.12.009_bib14","first-page":"189","article-title":"The acromegaly syndrome. Relation between clinical features, growth hormone values and radiological characteristics of the pituitary tumours","volume":"51","author":"Jadresic","year":"1982","journal-title":"QJ Med"},{"key":"10.1016\/j.domaniend.2005.12.009_bib15","first-page":"813","article-title":"Progestagen-induced and spontaneous canine acromegaly due to reversible growth hormone overproduction: clinical picture and pathogenesis","volume":"17","author":"Eigenmann","year":"1981","journal-title":"J Am Anim Hosp Assoc"},{"key":"10.1016\/j.domaniend.2005.12.009_bib16","series-title":"Clinical endocrinology of dogs and cats","first-page":"11","article-title":"Hypothalamus-pituitary system","author":"Rijnberk","year":"1996"},{"key":"10.1016\/j.domaniend.2005.12.009_bib17","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1016\/S0009-9260(86)80327-0","article-title":"The extrathoracic airway in acromegaly","volume":"37","author":"Morewood","year":"1986","journal-title":"Clin Radiol"},{"key":"10.1016\/j.domaniend.2005.12.009_bib18","doi-asserted-by":"crossref","first-page":"1173","DOI":"10.1210\/endo-106-4-1173","article-title":"Growth hormone prolactin and cortisol in dogs developing mammary nodules and an acromegaly-like appearance durind treatment with medroxyprogesterone acetate","volume":"106","author":"Concannon","year":"1980","journal-title":"Endocrinology"},{"key":"10.1016\/j.domaniend.2005.12.009_bib19","first-page":"534","article-title":"Acromegaly associated with transient overproduction of growth hormone in a dog","volume":"177","author":"Rijnberk","year":"1980","journal-title":"J Am Vet Med Assoc"},{"key":"10.1016\/j.domaniend.2005.12.009_bib20","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1677\/joe.0.1680059","article-title":"Primary hypothyroidism in dogs is associated with elevated growth hormone release","volume":"168","author":"Lee","year":"2001","journal-title":"J Endocrinol"},{"key":"10.1016\/j.domaniend.2005.12.009_bib21","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1177\/019262339802600201","article-title":"Pharmacological and toxicological effects of chronic porcine growth hormone administration in dogs","volume":"26","author":"Prahalada","year":"1998","journal-title":"Toxicol Pathol"},{"key":"10.1016\/j.domaniend.2005.12.009_bib22","doi-asserted-by":"crossref","first-page":"973","DOI":"10.1210\/jcem-55-5-973","article-title":"The effect of growth hormone on glucose metabolism and insulin secretion in man","volume":"55","author":"Bratusch\u2013Marrain","year":"1982","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.domaniend.2005.12.009_bib23","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1530\/acta.0.0980603","article-title":"Influence of medroxyprogesterone acetate (Provera) on plasma growth hormone levels and on carbohydrate metabolism. II. Studies in the ovariohysterectomized, oestradiol-primed bitch","volume":"98","author":"Eigenmann","year":"1981","journal-title":"Acta Endocrinol (Copenh)"},{"key":"10.1016\/j.domaniend.2005.12.009_bib24","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1210\/er.2002-0022","article-title":"Systemic complications of acromegaly: epidemiology, pathogenesis, and management","volume":"25","author":"Colao","year":"2004","journal-title":"Endocr Rev"},{"key":"10.1016\/j.domaniend.2005.12.009_bib25","series-title":"Endocrine diseases","first-page":"1403","author":"Peterson","year":"1994"},{"key":"10.1016\/j.domaniend.2005.12.009_bib26","doi-asserted-by":"crossref","first-page":"4821","DOI":"10.1210\/en.140.10.4821","article-title":"Expression of insulin-like growth factor I messenger ribonucleic acid in developing osteophytes in murine experimental osteoarthritis and in rats inoculated with growth hormone-secreting tumor","volume":"140","author":"Okazaki","year":"1999","journal-title":"Endocrinology"},{"key":"10.1016\/j.domaniend.2005.12.009_bib27","first-page":"523","article-title":"Gross and microscopic changes in the skin of dogs with progestagen-induced acromegaly and elevated growth hormone levels","volume":"19","author":"Scott","year":"1982","journal-title":"J Am Anim Hosp Assoc"},{"key":"10.1016\/j.domaniend.2005.12.009_bib28","doi-asserted-by":"crossref","first-page":"1820","DOI":"10.1001\/archinte.1982.00340230060013","article-title":"Histochemical characterization of the cutaneous involvement of acromegaly","volume":"142","author":"Matsuoka","year":"1982","journal-title":"Arch Intern Med"},{"key":"10.1016\/j.domaniend.2005.12.009_bib29","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1677\/joe.0.1520387","article-title":"Correlation between impairment of glucocorticoid feedback and the size of the pituitary gland in dogs with pituitary-dependent hyperadrenocorticism","volume":"152","author":"Kooistra","year":"1997","journal-title":"J Endocrinol"},{"key":"10.1016\/j.domaniend.2005.12.009_bib30","first-page":"128","article-title":"Incidence of cysts in pars distalis of mongrel dogs","volume":"48","author":"Rao","year":"1971","journal-title":"Indian Vet J"}],"container-title":["Domestic Animal Endocrinology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0739724006000130?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0739724006000130?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,4,16]],"date-time":"2019-04-16T17:15:13Z","timestamp":1555434913000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0739724006000130"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,1]]},"references-count":30,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2007,1]]}},"alternative-id":["S0739724006000130"],"URL":"https:\/\/doi.org\/10.1016\/j.domaniend.2005.12.009","relation":{},"ISSN":["0739-7240"],"issn-type":[{"value":"0739-7240","type":"print"}],"subject":[],"published":{"date-parts":[[2007,1]]}}}