{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,24]],"date-time":"2026-03-24T15:04:42Z","timestamp":1774364682359,"version":"3.50.1"},"reference-count":48,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2011,2,1]],"date-time":"2011-02-01T00:00:00Z","timestamp":1296518400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Domestic Animal Endocrinology"],"published-print":{"date-parts":[[2011,2]]},"DOI":"10.1016\/j.domaniend.2010.09.001","type":"journal-article","created":{"date-parts":[[2010,10,15]],"date-time":"2010-10-15T04:37:41Z","timestamp":1287117461000},"page":"67-76","source":"Crossref","is-referenced-by-count":8,"title":["Components of the porcine anterior pituitary insulin-like growth factor system throughout the estrous cycle"],"prefix":"10.1016","volume":"40","author":[{"given":"J.","family":"Clapper","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Taylor","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.domaniend.2010.09.001_bib1","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1210\/er.20.6.761","article-title":"The insulin-like growth factor-binding protein (IGFBP) superfamily","volume":"20","author":"Hwa","year":"1999","journal-title":"Endocr Rev"},{"key":"10.1016\/j.domaniend.2010.09.001_bib2","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1677\/joe.0.1750019","article-title":"IGF-binding proteins are multifunctional and act via IGF-dependent and -independent mechanisms","volume":"175","author":"Mohan","year":"2002","journal-title":"J Endocrinol"},{"key":"10.1016\/j.domaniend.2010.09.001_bib3","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1095\/biolreprod59.1.124","article-title":"Estradiol increases relative amounts of insulin-like growth factor binding protein (IGFBP)-3 in serum and expression of IGFBP-2 in anterior pituitaries of ewes","volume":"59","author":"Clapper","year":"1998","journal-title":"Biol Reprod"},{"key":"10.1016\/j.domaniend.2010.09.001_bib4","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1210\/en.136.1.62","article-title":"Insulin-like growth factor-I (IGF-I) and IGF-binding proteins in bovine sera and pituitaries at different stages of the estrous cycle","volume":"136","author":"Funston","year":"1995","journal-title":"Endocrinology"},{"key":"10.1016\/j.domaniend.2010.09.001_bib5","doi-asserted-by":"crossref","first-page":"214","DOI":"10.2527\/2002.801214x","article-title":"Administration of estradiol-17\u03b2 increases anterior pituitary IGF-I and relative amounts of serum and anterior pituitary IGF-binding proteins in barrows","volume":"80","author":"Rempel","year":"2002","journal-title":"J Anim Sci"},{"key":"10.1016\/j.domaniend.2010.09.001_bib6","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1677\/joe.1.06253","article-title":"Effects of decreased estradiol-17\u03b2 on the serum and anterior pituitary IGF-I system in pigs","volume":"187","author":"Hilleson-Gayne","year":"2005","journal-title":"J Endocrinol"},{"key":"10.1016\/j.domaniend.2010.09.001_bib7","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/S0378-4320(01)00190-7","article-title":"Insulin-like growth factor I enhances gonadotropin-releasing hormone-stimulated luteinizing hormone release from bovine anterior pituitary cells","volume":"70","author":"Hashizume","year":"2002","journal-title":"Anim Reprod Sci"},{"key":"10.1016\/j.domaniend.2010.09.001_bib8","doi-asserted-by":"crossref","first-page":"1359","DOI":"10.1095\/biolreprod53.6.1359","article-title":"Influence of stage of the estrous cycle on insulin-like growth factor-I modulation of luteinizing hormone secretion in the gilt","volume":"53","author":"Whitley","year":"1995","journal-title":"Biol Reprod"},{"key":"10.1016\/j.domaniend.2010.09.001_bib9","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1095\/biolreprod43.1.8","article-title":"Concentrations of insulin-like growth factor-I in blood and ovarian follicular fluid of cattle selected for twins","volume":"43","author":"Echternkamp","year":"1990","journal-title":"Biol Reprod"},{"key":"10.1016\/j.domaniend.2010.09.001_bib10","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1210\/jcem-51-4-781","article-title":"Inhibition of access of bound somatomedin to membrane receptor and immunobinding sites: a comparison of radioreceptor and radioimmunoassay of somatomedin in native and acid-ethanol-extracted serum","volume":"51","author":"Daughaday","year":"1980","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.domaniend.2010.09.001_bib11","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1038\/227680a0","article-title":"Cleavage of structural proteins during the assembly of the head of bacteriophage t4","volume":"227","author":"Laemmli","year":"1970","journal-title":"Nature"},{"key":"10.1016\/j.domaniend.2010.09.001_bib12","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1016\/0003-2697(86)90507-5","article-title":"Analysis of serum insulin-like growth factor binding proteins using western blotting: use of the method for titration of the binding proteins and competitive binding studies","volume":"154","author":"Hossenlopp","year":"1986","journal-title":"Anal Biochem"},{"key":"10.1016\/j.domaniend.2010.09.001_bib13","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1095\/biolreprod47.2.193","article-title":"Relationships among concentrations of steroids, inhibin, insulin-like growth factor-1 (IGF-1), and IGF-binding proteins during follicular development in weaned sows","volume":"47","author":"Howard","year":"1992","journal-title":"Biol Reprod"},{"key":"10.1016\/j.domaniend.2010.09.001_bib14","doi-asserted-by":"crossref","first-page":"1235","DOI":"10.2527\/jas1983.5751235x","article-title":"Influence of supplemental lighting during periods of increasing or decreasing daylength on the onset of puberty in gilts","volume":"57","author":"Diekman","year":"1983","journal-title":"J Anim Sci"},{"key":"10.1016\/j.domaniend.2010.09.001_bib15","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1016\/0039-128X(73)90104-9","article-title":"Influence of the site of conjugation on the specificity of antibodies to progesterone","volume":"22","author":"Niswender","year":"1973","journal-title":"Steroids"},{"key":"10.1016\/j.domaniend.2010.09.001_bib16","doi-asserted-by":"crossref","first-page":"e36","DOI":"10.1093\/nar\/30.9.e36","article-title":"Relative expression software tool (REST) for group-wise comparison and statistical analysis of relative expression results in real-time PCR","volume":"30","author":"Pfaffl","year":"2002","journal-title":"Nucleic Acids Res"},{"key":"10.1016\/j.domaniend.2010.09.001_bib17","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1002\/(SICI)1098-2795(199904)52:4<350::AID-MRD3>3.0.CO;2-M","article-title":"Expression of insulin-like growth factor binding protein-4, insulin-like growth factor-I receptor, and insulin-like growth factor-I in the mouse uterus throughout the estrous cycle","volume":"52","author":"Henemyre","year":"1999","journal-title":"Mol Reprod Dev"},{"key":"10.1016\/j.domaniend.2010.09.001_bib18","doi-asserted-by":"crossref","first-page":"5266","DOI":"10.1210\/en.136.12.5266","article-title":"Localization of messenger ribonucleic acids for insulin-like growth factor I (IGF-I), IGF-II, and the type 1 IGF receptor in the ovine ovary throughout the estrous cycle","volume":"136","author":"Perks","year":"1995","journal-title":"Endocrinology"},{"key":"10.1016\/j.domaniend.2010.09.001_bib19","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1530\/jrf.0.1040225","article-title":"Changes in insulin-like growth factor-binding protein-2 and -3 in follicular fluid during atresia of follicles grown after ovulation in pigs","volume":"104","author":"Guthrie","year":"1995","journal-title":"J Reprod Fertil"},{"key":"10.1016\/j.domaniend.2010.09.001_bib20","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1095\/biolreprod54.2.339","article-title":"Expression of the messenger ribonucleic acids for insulin-like growth factor-I and insulin-like growth factor binding proteins in porcine corpora lutea","volume":"54","author":"Gadsby","year":"1996","journal-title":"Biol Reprod"},{"key":"10.1016\/j.domaniend.2010.09.001_bib21","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/j.anireprosci.2005.03.002","article-title":"LH and IGF-1 release during oestrus and early luteal phase in lactating and non-lactating horse mares","volume":"91","author":"Deichsel","year":"2006","journal-title":"Anim Reprod Sci"},{"key":"10.1016\/j.domaniend.2010.09.001_bib22","doi-asserted-by":"crossref","first-page":"1059","DOI":"10.1210\/jc.77.4.1059","article-title":"Differential effects of insulin-like growth factor 1 on the hormonal product and proliferation of glycoprotein-secreting human pituitary adenomas","volume":"77","author":"Atkin","year":"1993","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.domaniend.2010.09.001_bib23","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1530\/acta.0.1250227","article-title":"Effect of insulin-like growth factor I on gonadotropin release from the hypothalamus-pituitary axis in vitro","volume":"125","author":"Kanematsu","year":"1991","journal-title":"Acta Endocrinol (Copenh)"},{"key":"10.1016\/j.domaniend.2010.09.001_bib24","doi-asserted-by":"crossref","first-page":"249","DOI":"10.2527\/2003.811249x","article-title":"Plasma gonadotropins and ovarian hormones during the estrous cycle in high compared to low ovulation rate gilts","volume":"81","author":"Knox","year":"2003","journal-title":"J Anim Sci"},{"key":"10.1016\/j.domaniend.2010.09.001_bib25","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1093\/biolreprod\/6.2.210","article-title":"Plasma estrogen, progesterone and luteinizing hormone levels during the estrous cycle in pigs","volume":"6","author":"Henricks","year":"1972","journal-title":"Biol Reprod"},{"key":"10.1016\/j.domaniend.2010.09.001_bib26","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1095\/biolreprod24.2.223","article-title":"Periestrous and midluteal time courses of circulating LH, FSH, prolactin, estradiol-17\u03b2 and progesterone in the domestic pig","volume":"24","author":"Van de Wiel","year":"1981","journal-title":"Biol Reprod"},{"key":"10.1016\/j.domaniend.2010.09.001_bib27","doi-asserted-by":"crossref","first-page":"2123","DOI":"10.1093\/humrep\/12.10.2123","article-title":"Changes in serum concentrations of growth hormone, insulin, insulin-like growth factor and insulin-like growth factor-binding proteins 1 and 3 and urinary growth hormone excretion during the menstrual cycle","volume":"12","author":"Juul","year":"1997","journal-title":"Hum Reprod"},{"key":"10.1016\/j.domaniend.2010.09.001_bib28","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/0303-7207(95)03654-P","article-title":"Estradiol and triiodothyronine increase production of insulin-like growth factor-I (IGF-I) and insulin-like growth factor binding protein-3 (IGFBP-3) by GH4C1 rat pituitary tumor cells","volume":"114","author":"Gilchrist","year":"1995","journal-title":"Mol Cell Endocrinol"},{"key":"10.1016\/j.domaniend.2010.09.001_bib29","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1677\/joe.0.1660247","article-title":"IGF-I stimulation of luteinizing hormone secretion, igf-binding proteins (IGFBPs) and expression of mRNAs for IGFs, IGF receptors and IGFBPs in the ovine pituitary gland","volume":"166","author":"Adam","year":"2000","journal-title":"J Endocrinol"},{"key":"10.1016\/j.domaniend.2010.09.001_bib30","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1016\/S0015-0282(16)57804-2","article-title":"Modulation of anterior pituitary luteinizing hormone response to gonadotropin-releasing hormone by insulin-like growth factor I in vitro","volume":"64","author":"Soldani","year":"1995","journal-title":"Fertil Steril"},{"key":"10.1016\/j.domaniend.2010.09.001_bib31","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1530\/eje.0.1440073","article-title":"Interactions of insulin-like growth factor-I, insulin and estradiol with GnRH-stimulated luteinizing hormone release from female rat gonadotrophs","volume":"144","author":"Xia","year":"2001","journal-title":"Eur J Endocrinol"},{"key":"10.1016\/j.domaniend.2010.09.001_bib32","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1210\/en.132.1.23","article-title":"Up-regulation of pituitary [125I]insulin-like growth factor-I (IGF-I) binding and IGF binding protein-2 and IGF-I gene expression by estrogen","volume":"132","author":"Michels","year":"1993","journal-title":"Endocrinology"},{"key":"10.1016\/j.domaniend.2010.09.001_bib33","doi-asserted-by":"crossref","first-page":"1415","DOI":"10.1095\/biolreprod62.5.1415","article-title":"Regulation and localization of insulin-like growth factor binding protein-5 gene expression in the uterus and placenta of the cyclic and early pregnant ewe","volume":"62","author":"Gadd","year":"2000","journal-title":"Biol Reprod"},{"key":"10.1016\/j.domaniend.2010.09.001_bib34","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1002\/jcb.240480212","article-title":"Cloning and sequence determination of bovine insulin-like growth factor binding protein-2 (IGFBP-2): Comparison of its structural and functional properties with IGFBP-1","volume":"48","author":"Bourner","year":"1992","journal-title":"J Cell Biochem"},{"key":"10.1016\/j.domaniend.2010.09.001_bib35","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1083\/jcb.121.3.679","article-title":"Extracellular matrix contains insulin-like growth factor binding protein-5: potentiation of the effects of IGF-I","volume":"121","author":"Jones","year":"1993","journal-title":"J Cell Biol"},{"key":"10.1016\/j.domaniend.2010.09.001_bib36","doi-asserted-by":"crossref","first-page":"7252","DOI":"10.1073\/pnas.77.12.7252","article-title":"Inhibition of biological activity of multiplication-stimulating activity by binding to its carrier protein","volume":"77","author":"Knauer","year":"1980","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.domaniend.2010.09.001_bib37","first-page":"70","article-title":"Structural and functional studies of insulin-like growth factor binding proteins in the ovary","volume":"3","author":"Ling","year":"1993","journal-title":"Growth Regul"},{"key":"10.1016\/j.domaniend.2010.09.001_bib38","doi-asserted-by":"crossref","first-page":"2495","DOI":"10.1210\/jc.81.7.2495","article-title":"Cellular localization and sex steroid regulation of insulin-like growth factor binding protein messenger ribonucleic acids in the primate myometrium","volume":"81","author":"Adesanya","year":"1996","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.domaniend.2010.09.001_bib39","doi-asserted-by":"crossref","first-page":"4210","DOI":"10.1210\/en.136.10.4210","article-title":"Insulin-like growth factor binding proteins-2 and -3 stimulate growth hormone receptor binding and mitogenesis in rat osteosarcoma cells","volume":"136","author":"Slootweg","year":"1995","journal-title":"Endocrinology"},{"key":"10.1016\/j.domaniend.2010.09.001_bib40","first-page":"834","article-title":"Overexpression of insulin-like growth factor-binding protein-2 results in increased tumorigenic potential in Y-1 adrenocortical tumor cells","volume":"60","author":"Hoeflich","year":"2000","journal-title":"Cancer Res"},{"key":"10.1016\/j.domaniend.2010.09.001_bib41","doi-asserted-by":"crossref","first-page":"4699","DOI":"10.1210\/en.140.10.4699","article-title":"Recombinant human insulin-like growth factor-binding protein-5 stimulates bone formation parameters in vitro and in vivo","volume":"140","author":"Richman","year":"1999","journal-title":"Endocrinology"},{"key":"10.1016\/j.domaniend.2010.09.001_bib42","first-page":"E744","article-title":"Insulin-like growth factor-binding protein-5 (IGFBP-5) stimulates phosphorylation of the IGFBP-5 receptor","volume":"274","author":"Andress","year":"1998","journal-title":"Am J Physiol"},{"key":"10.1016\/j.domaniend.2010.09.001_bib43","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1007\/s10620-006-9358-z","article-title":"Expression of IGFBP-2 in gastric carcinoma and relationship with clinicopathologic parameters and cell proliferation","volume":"52","author":"Zhang","year":"2007","journal-title":"Dig Dis Sci"},{"key":"10.1016\/j.domaniend.2010.09.001_bib44","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1385\/ENDO:14:3:399","article-title":"Insulin-like growth factor binding proteins in the bovine anterior pituitary","volume":"14","author":"Roberts","year":"2001","journal-title":"Endocrine"},{"key":"10.1016\/j.domaniend.2010.09.001_bib45","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1007\/s00441-006-0283-4","article-title":"Ultrastructural immunolocalization of IGF-1 and insulin receptors in rat pituitary culture: evidence of a functional interaction between gonadotroph and lactotroph cells","volume":"327","author":"Gutierrez","year":"2007","journal-title":"Cell Tissue Res"},{"key":"10.1016\/j.domaniend.2010.09.001_bib46","first-page":"573","article-title":"Insulin-like growth factor-I and its receptor in mouse pituitary glands","volume":"15","author":"Honda","year":"1998","journal-title":"Zoolog Sci"},{"key":"10.1016\/j.domaniend.2010.09.001_bib47","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1677\/joe.0.1450121","article-title":"IGF-I administration advances the decrease in hypersensitivity to oestradiol negative feedback inhibition of serum LH in adolescent female rhesus monkeys","volume":"145","author":"Wilson","year":"1995","journal-title":"J Endocrinol"},{"key":"10.1016\/j.domaniend.2010.09.001_bib48","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1530\/jrf.0.1130251","article-title":"Regulation of ovine GnRH receptor gene expression by progesterone and oestradiol","volume":"113","author":"Turzillo","year":"1998","journal-title":"J Reprod Fertil"}],"container-title":["Domestic Animal Endocrinology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S073972401000113X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S073972401000113X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,6,5]],"date-time":"2019-06-05T10:18:49Z","timestamp":1559729929000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S073972401000113X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,2]]},"references-count":48,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2011,2]]}},"alternative-id":["S073972401000113X"],"URL":"https:\/\/doi.org\/10.1016\/j.domaniend.2010.09.001","relation":{},"ISSN":["0739-7240"],"issn-type":[{"value":"0739-7240","type":"print"}],"subject":[],"published":{"date-parts":[[2011,2]]}}}