{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,4]],"date-time":"2026-02-04T16:53:40Z","timestamp":1770224020094,"version":"3.49.0"},"reference-count":44,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,8,22]],"date-time":"2021-08-22T00:00:00Z","timestamp":1629590400000},"content-version":"vor","delay-in-days":233,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100004586","name":"Funda\u00e7\u00e3o Carlos Chagas Filho de Amparo \u00e0 Pesquisa do Estado do Rio de Janeiro","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004586","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Domestic Animal Endocrinology"],"published-print":{"date-parts":[[2021,1]]},"DOI":"10.1016\/j.domaniend.2020.106532","type":"journal-article","created":{"date-parts":[[2020,7,31]],"date-time":"2020-07-31T21:39:26Z","timestamp":1596231566000},"page":"106532","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"special_numbering":"C","title":["Amyloidogenesis of feline amylin and plasma levels in cats with diabetes mellitus or pancreatitis"],"prefix":"10.1016","volume":"74","author":[{"given":"L.","family":"Jotha-Mattos","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.B.","family":"Vieira","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. da S.M.","family":"Castelo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.S. de M.","family":"Queiroz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.J.M.","family":"de Souza","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N.X.","family":"de Alencar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.M.T.R.","family":"Lima","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.domaniend.2020.106532_bib1","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/S0168-8227(00)00188-1","article-title":"Parallel changes of proinsulin and islet amyloid polypeptide in glucose intolerance","volume":"50","author":"MacNamara","year":"2000","journal-title":"Diabetes Res Clin Pract"},{"key":"10.1016\/j.domaniend.2020.106532_bib2","doi-asserted-by":"crossref","first-page":"3881","DOI":"10.1073\/pnas.84.11.3881","article-title":"Amyloid fibrils in human insulinoma and islets of Langerhans of the diabetic cat are derived from a neuropeptide-like protein also present in normal islet cells","volume":"84","author":"Westermark","year":"1987","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.domaniend.2020.106532_bib3","doi-asserted-by":"crossref","first-page":"8628","DOI":"10.1073\/pnas.84.23.8628","article-title":"Purification and characterization of a peptide from amyloid-rich pancreases of type 2 diabetic patients","volume":"84","author":"Cooper","year":"1987","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.domaniend.2020.106532_bib4","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1016\/j.tvjl.2009.02.011","article-title":"Amylin reduces plasma glucagon concentration in cats","volume":"184","author":"Furrer","year":"2010","journal-title":"Vet J"},{"key":"10.1016\/j.domaniend.2020.106532_bib5","doi-asserted-by":"crossref","first-page":"564","DOI":"10.1124\/pr.115.010629","article-title":"Amylin: pharmacology, physiology, and clinical potential","volume":"67","author":"Hay","year":"2015","journal-title":"Pharmacol Rev"},{"key":"10.1016\/j.domaniend.2020.106532_bib6","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1152\/physrev.00042.2009","article-title":"Islet amyloid polypeptide, islet amyloid, and diabetes mellitus","volume":"91","author":"Westermark","year":"2011","journal-title":"Physiol Rev"},{"key":"10.1016\/j.domaniend.2020.106532_bib7","doi-asserted-by":"crossref","first-page":"118","DOI":"10.2337\/diacare.39.1.118","article-title":"Structure of cat islet amyloid polypeptide and identification of amino acid residues of potential significance for islet amyloid formation","volume":"39","author":"Betsholtz","year":"1990","journal-title":"Diabetes"},{"key":"10.1016\/j.domaniend.2020.106532_bib8","doi-asserted-by":"crossref","first-page":"2143","DOI":"10.1016\/S0002-9440(10)64852-3","article-title":"A feline model of experimentally induced islet amyloidosis","volume":"157","author":"Hoenig","year":"2000","journal-title":"Am J Pathol"},{"key":"10.1016\/j.domaniend.2020.106532_bib9","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1016\/j.jcpa.2014.06.004","article-title":"Oxidative modification, inflammation and amyloid in the normal and diabetic cat pancreas","volume":"151","author":"Herndon","year":"2014","journal-title":"J Comp Pathol"},{"key":"10.1016\/j.domaniend.2020.106532_bib10","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1210\/er.2007-0037","article-title":"Islet amyloid in type 2 diabetes, and the toxic oligomer hypothesis","volume":"29","author":"Haataja","year":"2008","journal-title":"Endocr Rev"},{"key":"10.1016\/j.domaniend.2020.106532_bib11","first-page":"245","article-title":"Impaired glucose tolerance is associated with increased islet amyloid polypeptide (IAPP) immunoreactivity in pancreatic beta cells","volume":"135","author":"Johnson","year":"1989","journal-title":"Am J Pathol"},{"key":"10.1016\/j.domaniend.2020.106532_bib12","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1590\/0001-3765201720160394","article-title":"Subclinical diabetes","volume":"89","author":"Lima","year":"2017","journal-title":"An Acad Bras Cienc"},{"key":"10.1016\/j.domaniend.2020.106532_bib13","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1016\/S2213-8587(17)30011-6","article-title":"Prediabetes definitions and clinical outcomes","volume":"5","author":"Lima","year":"2017","journal-title":"Lancet Diabetes Endocrinol"},{"key":"10.1016\/j.domaniend.2020.106532_bib14","doi-asserted-by":"crossref","first-page":"1487","DOI":"10.2337\/diacare.27.6.1487","article-title":"Use and abuse of HOMA modeling","volume":"27","author":"Wallace","year":"2004","journal-title":"Diabetes Care"},{"key":"10.1016\/j.domaniend.2020.106532_bib15","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1007\/BF00500385","article-title":"Plasma islet amyloid polypeptide (Amylin) levels and their responses to oral glucose in type 2 (non-insulin-dependent) diabetic patients","volume":"34","author":"Sanke","year":"1991","journal-title":"Diabetologia"},{"key":"10.1016\/j.domaniend.2020.106532_bib16","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/0168-8227(92)90074-2","article-title":"Plasma islet amyloid polypeptide levels in obesity, impaired glucose tolerance and non-insulin-dependent diabetes mellitus","volume":"15","author":"Enoki","year":"1992","journal-title":"Diabetes Res Clin Pract"},{"key":"10.1016\/j.domaniend.2020.106532_bib17","doi-asserted-by":"crossref","first-page":"1052","DOI":"10.2460\/ajvr.72.8.1052","article-title":"Evaluation of plasma islet amyloid polypeptide and serum glucose and insulin concentrations in nondiabetic cats classified by body condition score and in cats with naturally occurring diabetes mellitus","volume":"72","author":"Henson","year":"2011","journal-title":"Am J Vet Res"},{"key":"10.1016\/j.domaniend.2020.106532_bib18","first-page":"153","article-title":"Diabetes mellitus secondary to chronic pancreatitis","volume":"40","author":"Larsen","year":"1993","journal-title":"Dan Med Bull"},{"key":"10.1016\/j.domaniend.2020.106532_bib19","doi-asserted-by":"crossref","first-page":"2072S","DOI":"10.1093\/jn\/134.8.2072S","article-title":"Canine and feline diabetes mellitus: nature or nurture?","volume":"134","author":"Rand","year":"2004","journal-title":"J Nutr"},{"key":"10.1016\/j.domaniend.2020.106532_bib20","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1111\/jsap.12295","article-title":"Diabetes mellitus and pancreatitis--cause or effect?","volume":"56","author":"Davison","year":"2015","journal-title":"J Small Anim Pract"},{"key":"10.1016\/j.domaniend.2020.106532_bib21","first-page":"dc170542","article-title":"Incidence, demographics, and clinical characteristics of diabetes of the exocrine pancreas (type 3c): a retrospective cohort study","author":"Woodmansey","year":"2017","journal-title":"Diabetes Care"},{"key":"10.1016\/j.domaniend.2020.106532_bib22","first-page":"258","article-title":"Elevated fasting plasma level of islet amyloid polypeptide (IAPP) in chronic alcoholic pancreatitis (CAP)","volume":"50","author":"Gasiorowska","year":"2003","journal-title":"Hepatogastroenterology"},{"key":"10.1016\/j.domaniend.2020.106532_bib23","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1080\/13813455.2017.1308382","article-title":"Fasting levels of insulin and amylin after acute pancreatitis are associated with pro-inflammatory cytokines","volume":"123","author":"Gillies","year":"2017","journal-title":"Arch Physiol Biochem"},{"key":"10.1016\/j.domaniend.2020.106532_bib24","doi-asserted-by":"crossref","first-page":"G50","DOI":"10.1152\/ajpgi.00074.2016","article-title":"Relationship between pancreatic hormones and glucose metabolism: a cross-sectional study in patients after acute pancreatitis","volume":"311","author":"Pendharkar","year":"2016","journal-title":"Am J Physiol Gastrointest Liver Physiol"},{"key":"10.1016\/j.domaniend.2020.106532_bib25","doi-asserted-by":"crossref","first-page":"5036","DOI":"10.1073\/pnas.87.13.5036","article-title":"Islet amyloid polypeptide: pinpointing amino acid residues linked to amyloid fibril formation","volume":"87","author":"Westermark","year":"1990","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.domaniend.2020.106532_bib26","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.bpc.2016.09.007","article-title":"Amyloidogenesis of the amylin analogue pramlintide","volume":"219","author":"da Silva","year":"2016","journal-title":"Biophys Chem"},{"key":"10.1016\/j.domaniend.2020.106532_bib27","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/j.bpc.2016.09.008","article-title":"Regulation of the assembly and amyloid aggregation of murine amylin by zinc","volume":"218","author":"Erthal","year":"2016","journal-title":"Biophys Chem"},{"key":"10.1016\/j.domaniend.2020.106532_bib28","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s11010-018-3288-x","article-title":"The toxic nature of murine amylin and the immune responsivity of pancreatic islet to conformational antibody in mice","volume":"447","author":"Erthal","year":"2018","journal-title":"Mol Cell Biochem"},{"key":"10.1016\/j.domaniend.2020.106532_bib29","doi-asserted-by":"crossref","first-page":"165675","DOI":"10.1016\/j.bbadis.2020.165675","article-title":"Dietary zinc restriction promotes degeneration of the endocrine pancreas in mice","volume":"1866","author":"Sisnande","year":"2020","journal-title":"Biochim Biophys Acta Mol Basis Dis"},{"key":"10.1016\/j.domaniend.2020.106532_bib30","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/j.bpc.2013.07.013","article-title":"Stepwise oligomerization of murine amylin and assembly of amyloid fibrils","volume":"180\u2013181","author":"Palmieri","year":"2013","journal-title":"Biophys Chem"},{"key":"10.1016\/j.domaniend.2020.106532_bib31","doi-asserted-by":"crossref","first-page":"285","DOI":"10.5326\/0460285","article-title":"AAHA nutritional assessment guidelines for dogs and cats","volume":"46","author":"Baldwin","year":"2010","journal-title":"J Am Anim Hosp Assoc"},{"key":"10.1016\/j.domaniend.2020.106532_bib32","doi-asserted-by":"crossref","first-page":"1","DOI":"10.5326\/JAAHA-MS-6822","article-title":"2018 AAHA diabetes management guidelines for dogs and cats","volume":"54","author":"Behrend","year":"2018","journal-title":"J Am Anim Hosp Assoc"},{"key":"10.1016\/j.domaniend.2020.106532_bib33","doi-asserted-by":"crossref","first-page":"1408","DOI":"10.1021\/acschembio.9b01050","article-title":"Analysis of amylin consensus sequences suggests that human amylin is not optimized to minimize amyloid formation and provides clues to Factors that modulate amyloidogenicity","volume":"15","author":"Noh","year":"2020","journal-title":"ACS Chem Biol"},{"key":"10.1016\/j.domaniend.2020.106532_bib34","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1016\/j.jcpa.2017.03.006","article-title":"Obesity and associated comorbidities in people and companion animals: a one health perspective","volume":"156","author":"Chandler","year":"2017","journal-title":"J Comp Pathol"},{"key":"10.1016\/j.domaniend.2020.106532_bib35","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1177\/030098588502200308","article-title":"High dose intravenous glucose tolerance test and serum insulin and glucagon levels in diabetic and non-diabetic cats: relationships to insular amyloidosis","volume":"22","author":"O\u2019Brien","year":"1985","journal-title":"Vet Pathol"},{"key":"10.1016\/j.domaniend.2020.106532_bib36","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1177\/030098588101800507","article-title":"Feline insular amyloid: association with diabetes mellitus","volume":"18","author":"Yano","year":"1981","journal-title":"Vet Pathol"},{"key":"10.1016\/j.domaniend.2020.106532_bib37","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1177\/0300985815591078","article-title":"Endocrine pancreas in cats with diabetes mellitus","volume":"53","author":"Zini","year":"2016","journal-title":"Vet Pathol"},{"key":"10.1016\/j.domaniend.2020.106532_bib38","doi-asserted-by":"crossref","first-page":"14077","DOI":"10.1074\/jbc.275.19.14077","article-title":"Alzheimer\u2019s beta-amyloid, human islet amylin, and prion protein fragment evoke intracellular free calcium elevations by a common mechanism in a hypothalamic GnRH neuronal cell line","volume":"275","author":"Kawahara","year":"2000","journal-title":"J Biol Chem"},{"key":"10.1016\/j.domaniend.2020.106532_bib39","doi-asserted-by":"crossref","first-page":"927","DOI":"10.1111\/jvim.14357","article-title":"What\u2019s in a name? Classification of diabetes mellitus in veterinary medicine and why it matters","volume":"30","author":"Gilor","year":"2016","journal-title":"J Vet Intern Med"},{"key":"10.1016\/j.domaniend.2020.106532_bib40","doi-asserted-by":"crossref","first-page":"S81","DOI":"10.2337\/dc14-S081","article-title":"Diagnosis and classification of diabetes mellitus","volume":"37","year":"2014","journal-title":"Diabetes Care"},{"key":"10.1016\/j.domaniend.2020.106532_bib41","doi-asserted-by":"crossref","first-page":"1610","DOI":"10.1017\/S000711450999359X","article-title":"Postprandial response of plasma insulin, amylin and acylated ghrelin to various test meals in lean and obese cats","volume":"103","author":"Martin","year":"2010","journal-title":"Br J Nutr"},{"key":"10.1016\/j.domaniend.2020.106532_bib42","doi-asserted-by":"crossref","first-page":"47S","DOI":"10.1177\/0145721715607642","article-title":"Role of amylin in type 1 and type 2 diabetes","volume":"41","author":"Hieronymus","year":"2015","journal-title":"Diabetes Educ"},{"key":"10.1016\/j.domaniend.2020.106532_bib43","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/j.rvsc.2010.01.006","article-title":"Hyperglycaemia but not hyperlipidaemia decreases serum amylase and increases neutrophils in the exocrine pancreas of cats","volume":"89","author":"Zini","year":"2010","journal-title":"Res Vet Sci"},{"key":"10.1016\/j.domaniend.2020.106532_bib44","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1016\/j.cvsm.2012.12.001","article-title":"Pancreatitis and diabetes in cats","volume":"43","author":"Caney","year":"2013","journal-title":"Vet Clin North Am Small Anim Pract"}],"container-title":["Domestic Animal Endocrinology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0739724020300990?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0739724020300990?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T18:55:01Z","timestamp":1760036101000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0739724020300990"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,1]]},"references-count":44,"alternative-id":["S0739724020300990"],"URL":"https:\/\/doi.org\/10.1016\/j.domaniend.2020.106532","relation":{},"ISSN":["0739-7240"],"issn-type":[{"value":"0739-7240","type":"print"}],"subject":[],"published":{"date-parts":[[2021,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Amyloidogenesis of feline amylin and plasma levels in cats with diabetes mellitus or pancreatitis","name":"articletitle","label":"Article Title"},{"value":"Domestic Animal Endocrinology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.domaniend.2020.106532","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"106532"}}