{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T01:47:34Z","timestamp":1760060854492,"version":"build-2065373602"},"reference-count":36,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"name":"Charles V. Cusimano Equine Health Studies Program"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Domestic Animal Endocrinology"],"published-print":{"date-parts":[[2021,1]]},"DOI":"10.1016\/j.domaniend.2020.106536","type":"journal-article","created":{"date-parts":[[2020,8,7]],"date-time":"2020-08-07T11:58:00Z","timestamp":1596801480000},"page":"106536","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"special_numbering":"C","title":["Plasma prolactin, thyroid-stimulating hormone, melanocyte-stimulating hormone, and adrenocorticotropin responses to thyrotropin-releasing hormone in mares treated with detomidine and butorphanol"],"prefix":"10.1016","volume":"74","author":[{"given":"E.L.","family":"Oberhaus","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.L.","family":"Thompson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.E.","family":"Kerrigan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.M.","family":"Chapman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.domaniend.2020.106536_bib1","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/0739-7240(84)90006-7","article-title":"Thyroid stimulating hormone and prolactin secretion after thyrotropin releasing hormone administration to mares: dose response during anestrus in winter and during estrus in summer","volume":"1","author":"Thompson","year":"1984","journal-title":"Domest Anim Endocrinol"},{"key":"10.1016\/j.domaniend.2020.106536_bib2","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1016\/j.domaniend.2013.03.001","article-title":"Changes in plasma melanocyte-stimulating hormone, ACTH, prolactin, GH, LH, FSH, and thyroid-stimulating hormone in response to injection of sulpiride, thyrotropin-releasing hormone, or vehicle in insulin-sensitive and -insensitive mares","volume":"44","author":"Valencia","year":"2013","journal-title":"Domest Anim Endocrinol"},{"key":"10.1016\/j.domaniend.2020.106536_bib3","doi-asserted-by":"crossref","first-page":"417","DOI":"10.2460\/javma.231.3.417","article-title":"Adrenocorticotropin concentration following administration of thyrotropin-releasing hormone in healthy horses and those with pituitary pars intermedia dysfunction and pituitary gland hyperplasia","volume":"231","author":"Beech","year":"2007","journal-title":"J Am Vet Med Assoc"},{"key":"10.1016\/j.domaniend.2020.106536_bib4","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1016\/j.domaniend.2005.07.005","article-title":"Alpha-melanocyte stimulating hormone release in response to thyrotropin releasing hormone in healthy horses, horses with pituitary pars intermedia dysfunction and equine pars intermedia explants","volume":"30","author":"McFarlane","year":"2006","journal-title":"Domest Anim Endocrinol"},{"key":"10.1016\/j.domaniend.2020.106536_bib5","doi-asserted-by":"crossref","first-page":"1305","DOI":"10.2460\/javma.238.10.1305","volume":"238","author":"Beech","year":"2011","journal-title":"J Am Vet Med Assoc"},{"author":"Schott","key":"10.1016\/j.domaniend.2020.106536_bib6"},{"key":"10.1016\/j.domaniend.2020.106536_bib7","doi-asserted-by":"crossref","first-page":"874","DOI":"10.1046\/j.1365-2826.2000.00542.x","article-title":"The effect of the alpha-2-adrenergic agonist, clonidine, on secretion patterns and rates of adrenocorticotropic hormone and its secretagogues in the horse","volume":"12","author":"Alexander","year":"2000","journal-title":"J Neuroendocrinol"},{"key":"10.1016\/j.domaniend.2020.106536_bib8","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1677\/joe.0.1690511","article-title":"Opioidergic inhibition of luteinising hormone and prolactin release changes during pregnancy in pony mares","volume":"169","author":"Aurich","year":"2001","journal-title":"J Endocrinol"},{"key":"10.1016\/j.domaniend.2020.106536_bib9","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1046\/j.1439-0531.2002.00370.x","article-title":"Dopaminergic and opioidergic regulation of gonadotropin and prolactin release in stallions","volume":"37","author":"Aurich","year":"2002","journal-title":"Reprod Domest Anim"},{"key":"10.1016\/j.domaniend.2020.106536_bib10","first-page":"195","article-title":"Opioidergic and dopaminergic effects on LH and prolactin release in pony mares at different times of the year","volume":"56","author":"Aurich","year":"2000","journal-title":"J Reprod Fertil Suppl"},{"key":"10.1016\/j.domaniend.2020.106536_bib11","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1111\/j.2042-3306.1983.tb01826.x","article-title":"Relationship between condition score, physical measurements and body fat percentage in mares","volume":"15","author":"Henneke","year":"1983","journal-title":"Equine Vet J"},{"key":"10.1016\/j.domaniend.2020.106536_bib12","doi-asserted-by":"crossref","first-page":"2556","DOI":"10.2527\/1991.6962556x","article-title":"Responses of cortisol and prolactin to sexual excitement and stress in stallions and geldings","volume":"69","author":"Colborn","year":"1991","journal-title":"J Anim Sci"},{"key":"10.1016\/j.domaniend.2020.106536_bib13","doi-asserted-by":"crossref","first-page":"735","DOI":"10.2527\/2001.793735x","article-title":"Pituitary hormone and insulin responses to infusion of amino acids and N-methyl-d,l-aspartate in horses","volume":"79","author":"Sticker","year":"2001","journal-title":"J Anim Sci"},{"key":"10.1016\/j.domaniend.2020.106536_bib14","doi-asserted-by":"crossref","first-page":"1463","DOI":"10.2460\/ajvr.2004.65.1463","article-title":"Effects of season and sample handling on measurement of plasma alpha-melanocyte-stimulating hormone concentrations in horses and ponies","volume":"65","author":"McFarlane","year":"2004","journal-title":"Am J Vet Res"},{"year":"1997","author":"Steel","series-title":"Principles and procedures of statistics: a biometrical approach","key":"10.1016\/j.domaniend.2020.106536_bib15"},{"key":"10.1016\/j.domaniend.2020.106536_bib16","doi-asserted-by":"crossref","first-page":"102842","DOI":"10.1016\/j.jevs.2019.102842","article-title":"Effects of epinephrine, detomidine and butorphanol on assessments of insulin sensitivity in mares","volume":"85","author":"Kerrigan","year":"2020","journal-title":"J Equine Vet Sci"},{"key":"10.1016\/j.domaniend.2020.106536_bib17","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1073\/pnas.69.1.283","article-title":"Binding of thyrotropin-releasing hormone to plasma membranes of bovine anterior pituitary gland (hormone receptor-adenylate cyclase-equilibrium constant-(3H)thyrotropin)","volume":"69","author":"Labrie","year":"1972","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.domaniend.2020.106536_bib18","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1016\/0014-4827(79)90317-3","article-title":"Autohistoradiographic localization of thyrotropin-releasing hormone (TRH)-binding sites in cultured rat pituitary cells","volume":"122","author":"Antakly","year":"1979","journal-title":"Exp Cell Res"},{"key":"10.1016\/j.domaniend.2020.106536_bib19","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/j.jevs.2017.08.020","article-title":"Thyrotropin releasing hormone: a powerful tripeptide with diverse effects in horses","volume":"59","author":"Thompson","year":"2017","journal-title":"J Equine Vet Sci"},{"key":"10.1016\/j.domaniend.2020.106536_bib20","first-page":"55","article-title":"Role of the equine hypothalamic-pituitary pars intermedia axis in health and disease","volume":"vol. 52","author":"McFarlane","year":"2006"},{"key":"10.1016\/j.domaniend.2020.106536_bib21","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1210\/endo-107-1-108","volume":"107","author":"Cote","year":"1980","journal-title":"Endocrinology"},{"key":"10.1016\/j.domaniend.2020.106536_bib22","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1016\/S0278-5846(82)80118-8","article-title":"Beta-Adrenergic, CRF-ergic and dopaminergic mechanisms controlling alpha-MSH secretion in rat pars intermedia cells in primary culture","volume":"6","author":"Meunier","year":"1982","journal-title":"Prog Neuropsychopharmacol Biol Psychiatry"},{"key":"10.1016\/j.domaniend.2020.106536_bib23","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1159\/000125537","article-title":"Dopaminergic and beta-adrenergic receptor control of alpha-melanocyte-stimulating hormone secretion during stress","volume":"52","author":"Lindley","year":"1990","journal-title":"Neuroendocrinology"},{"key":"10.1016\/j.domaniend.2020.106536_bib24","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1210\/endo-109-3-757","article-title":"Characteristics of the alpha-adrenergic stimulation of adrenocorticotropin secretion in rat anterior pituitary cells","volume":"109","author":"Giguere","year":"1981","journal-title":"Endocrinology"},{"key":"10.1016\/j.domaniend.2020.106536_bib25","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1210\/endo-113-1-133","article-title":"Alpha 1-adrenoreceptors on intact rat anterior pituitary cells: correlation with adrenergic stimulation of thyrotropin secretion","volume":"113","author":"Peters","year":"1983","journal-title":"Endocrinology"},{"key":"10.1016\/j.domaniend.2020.106536_bib26","doi-asserted-by":"crossref","first-page":"1419","DOI":"10.1210\/endo-122-4-1419","article-title":"Alpha 1-adrenergic stimulation of in\u00a0vitro growth hormone release and cytosolic free Ca2+ in rat somatotrophs","volume":"122","author":"Pandiella","year":"1988","journal-title":"Endocrinology"},{"key":"10.1016\/j.domaniend.2020.106536_bib27","doi-asserted-by":"crossref","first-page":"105","DOI":"10.3181\/00379727-192-42962","article-title":"Possible involvement of endogenous opioid peptides in prolactin secretion induced by \u03b1 2-adrenergic stimulation in rats","volume":"192","author":"Koshiyama","year":"1989","journal-title":"Exp Biol Med"},{"key":"10.1016\/j.domaniend.2020.106536_bib28","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1159\/000124643","article-title":"Alpha-2-adrenergic control of prolactin release","volume":"44","author":"Lien","year":"1986","journal-title":"Neuroendocrinology"},{"key":"10.1016\/j.domaniend.2020.106536_bib29","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1042\/bj2920283","article-title":"Coupling of the alpha 2-adrenergic receptor to the inhibitory G-protein Gi and adenylate cyclase in HT29 cells","volume":"292","author":"Remaury","year":"1993","journal-title":"Biochem J"},{"key":"10.1016\/j.domaniend.2020.106536_bib30","doi-asserted-by":"crossref","first-page":"958","DOI":"10.1210\/endo-128-2-958","article-title":"Activation of alpha 2-adrenergic receptors decreases Ca2+ influx to inhibit insulin secretion in a hamster beta-cell line: an action mediated by a guanosine triphosphate-binding protein","volume":"128","author":"Hsu","year":"1991","journal-title":"Endocrinology"},{"key":"10.1016\/j.domaniend.2020.106536_bib31","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1016\/0278-5846(89)90051-1","article-title":"Medetomidine \u2014 a novel \u03b12-adrenoceptor agonist: a review of its pharmacodynamic effects","volume":"13","author":"Scheinin","year":"1989","journal-title":"Prog Neuropsychopharmacol Biol Psychiatry"},{"key":"10.1016\/j.domaniend.2020.106536_bib32","first-page":"35","article-title":"Pharmacology of detomidine and other \u03b12-adrenoreceptor agonists in the brain","volume":"82","author":"Virtanen","year":"1986","journal-title":"Acta Vet Scand Suppl"},{"key":"10.1016\/j.domaniend.2020.106536_bib33","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1046\/j.1365-2885.2000.00240.x","article-title":"Correlation between serum concentrations following continuous intravenous infusion of dexmedetomidine or medetomidine in cats and their sedative and analgesic effects","volume":"23","author":"Anash","year":"2000","journal-title":"J Vet Pharmacol Ther"},{"key":"10.1016\/j.domaniend.2020.106536_bib34","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/0093-691X(91)90435-G","article-title":"Xylazine-induced ex copula ejaculation in stallions","volume":"36","author":"McDonnell","year":"1991","journal-title":"Theriogenology"},{"key":"10.1016\/j.domaniend.2020.106536_bib35","first-page":"221","article-title":"Fertility of detomidine HCl induced ex copula ejaculated stallion semen","volume":"vol. 45","author":"Rowley","year":"1999"},{"key":"10.1016\/j.domaniend.2020.106536_bib36","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1016\/j.pharmthera.2006.09.004","article-title":"Thyrotropin-releasing hormone and its receptors\u2014a hypothesis for binding and receptor activation","volume":"113","author":"Engel","year":"2007","journal-title":"Pharmacol Ther"}],"container-title":["Domestic Animal Endocrinology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S073972402030103X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S073972402030103X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T18:56:13Z","timestamp":1760036173000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S073972402030103X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,1]]},"references-count":36,"alternative-id":["S073972402030103X"],"URL":"https:\/\/doi.org\/10.1016\/j.domaniend.2020.106536","relation":{},"ISSN":["0739-7240"],"issn-type":[{"type":"print","value":"0739-7240"}],"subject":[],"published":{"date-parts":[[2021,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Plasma prolactin, thyroid-stimulating hormone, melanocyte-stimulating hormone, and adrenocorticotropin responses to thyrotropin-releasing hormone in mares treated with detomidine and butorphanol","name":"articletitle","label":"Article Title"},{"value":"Domestic Animal Endocrinology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.domaniend.2020.106536","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"106536"}}