{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T13:18:52Z","timestamp":1791206332793,"version":"4.1.0"},"reference-count":25,"publisher":"Elsevier BV","issue":"2-3","license":[{"start":{"date-parts":[[2007,12,1]],"date-time":"2007-12-01T00:00:00Z","timestamp":1196467200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Drug and Alcohol Dependence"],"published-print":{"date-parts":[[2007,12]]},"DOI":"10.1016\/j.drugalcdep.2007.05.021","type":"journal-article","created":{"date-parts":[[2007,7,13]],"date-time":"2007-07-13T11:45:21Z","timestamp":1184327121000},"page":"205-212","source":"Crossref","is-referenced-by-count":31,"title":["A double-blind, placebo-controlled trial of reserpine for the treatment of cocaine dependence"],"prefix":"10.1016","volume":"91","author":[{"given":"Theresa","family":"Winhusen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eugene","family":"Somoza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ofra","family":"Sarid-Segal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R. Jeffrey","family":"Goldsmith","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Judy M.","family":"Harrer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Florence S.","family":"Coleman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberta","family":"Kahn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sabuhi","family":"Osman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juris","family":"Mezinskis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shou-Hua","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Lewis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maryam","family":"Afshar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Domenic A.","family":"Ciraulo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"Horn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Margaret A.","family":"Montgomery","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmed","family":"Elkashef","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.drugalcdep.2007.05.021_bib1","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1017\/S003329170001432X","article-title":"Antihypertensive drugs and depression: a reappraisal","volume":"8","author":"Bant","year":"1978","journal-title":"Psychol. Med."},{"issue":"2","key":"10.1016\/j.drugalcdep.2007.05.021_bib2","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1076\/jhin.12.2.207.15535","article-title":"The myth of reserpine-induced depression: role in the historical development of the monoamine hypothesis","volume":"12","author":"Baumeister","year":"2003","journal-title":"J. Hist. Neurosci."},{"issue":"12","key":"10.1016\/j.drugalcdep.2007.05.021_bib3","first-page":"542","article-title":"Reserpine and phencyclidine-associated psychosis: three case reports","volume":"46","author":"Berlant","year":"1985","journal-title":"J. Clin. Psychiatry"},{"issue":"Suppl. 1","key":"10.1016\/j.drugalcdep.2007.05.021_bib4","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1111\/j.1360-0443.2005.00983.x","article-title":"A medication screening trial evaluation of reserpine, gabapentin, and lamotrigine pharmacotherapy of cocaine dependence","volume":"100","author":"Berger","year":"2005","journal-title":"Addiction"},{"key":"10.1016\/j.drugalcdep.2007.05.021_bib5","unstructured":"Brief, D.J., Bollinger, A.R., Horton, G.E., LoCastro, J.S. Integrated treatment for addictions: education, motivational enhancement, and skills building for alcohol & drug addiction, unpublished manuscript."},{"key":"10.1016\/j.drugalcdep.2007.05.021_bib6","doi-asserted-by":"crossref","first-page":"5274","DOI":"10.1073\/pnas.85.14.5274","article-title":"Drugs abused by humans preferentially increase synaptic dopamine concentrations in the mesolimbic system of freely moving rats","volume":"85","author":"Di Chiara","year":"1988","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.drugalcdep.2007.05.021_bib7","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1037\/0022-006X.68.1.134","article-title":"The timeline followback reports of psychoactive substance use by drug-abusing patients: psychometric properties","volume":"68","author":"Fals-Stewart","year":"2000","journal-title":"J. Consult. Clin. Psychol."},{"key":"10.1016\/j.drugalcdep.2007.05.021_bib8","first-page":"231","article-title":"Effects of reserpine on extracellular caudate dopamine and hippocampus norepinephrine responses to amphetamine and cocaine: mechanistic and behavioral considerations","volume":"274","author":"Florin","year":"1995","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1016\/j.drugalcdep.2007.05.021_bib9","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/0024-3205(78)90254-0","article-title":"The reserpine receptor","volume":"23","author":"Giachetti","year":"1978","journal-title":"Life Sci."},{"key":"10.1016\/j.drugalcdep.2007.05.021_bib10","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1016\/S0025-7125(16)32522-6","article-title":"The treatment of chronic hypertension","volume":"55","author":"Gilmore","year":"1971","journal-title":"Med. Clin. North Am."},{"key":"10.1016\/j.drugalcdep.2007.05.021_bib11","first-page":"435","article-title":"Depressions following reserpine: a reevaluation","volume":"3","author":"Goodwin","year":"1971","journal-title":"Semin. Psychiatry"},{"key":"10.1016\/j.drugalcdep.2007.05.021_bib12","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/j.drugalcdep.2005.06.010","article-title":"Bromocriptine treatment for cocaine addiction: association with plasma prolactin levels","volume":"81","author":"Gorelick","year":"2006","journal-title":"Drug Alcohol Depend."},{"key":"10.1016\/j.drugalcdep.2007.05.021_bib13","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1242\/jeb.196.1.251","article-title":"Biochemistry and molecular biology of the vesicular monoamine transporter from chromaffin granules","volume":"196","author":"Henry","year":"1994","journal-title":"J. Exp. Biol."},{"issue":"6","key":"10.1016\/j.drugalcdep.2007.05.021_bib14","doi-asserted-by":"crossref","first-page":"813","DOI":"10.1016\/j.amjhyper.2005.01.020","article-title":"Isradipine decreases the hemodynamic response of cocaine and methamphetamine results from two human laboratory studies: results from two human laboratory studies","volume":"18","author":"Johnson","year":"2005","journal-title":"Am. J. Hypertens."},{"issue":"3","key":"10.1016\/j.drugalcdep.2007.05.021_bib15","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1097\/01.yco.0000165592.52811.84","article-title":"Emerging research on methamphetamine","volume":"18","author":"Maxwell","year":"2005","journal-title":"Curr. Opin. Psychiatry"},{"key":"10.1016\/j.drugalcdep.2007.05.021_bib16","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/0740-5472(92)90062-S","article-title":"The fifth edition of the Addiction Severity Index","volume":"9","author":"McLellan","year":"1992","journal-title":"J. Subst. Abuse Treat."},{"key":"10.1016\/j.drugalcdep.2007.05.021_bib17","doi-asserted-by":"crossref","first-page":"577","DOI":"10.3928\/0048-5713-19981001-08","article-title":"Craving and withdrawal symptoms for various drugs of abuse","volume":"28","author":"Mezinskis","year":"1998","journal-title":"Psychiatr. Ann."},{"key":"10.1016\/j.drugalcdep.2007.05.021_bib18","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1111\/j.1360-0443.1997.tb02938.x","article-title":"Assessment of cocaine use with quantitative urinalysis and estimation of new uses","volume":"92","author":"Preston","year":"1997","journal-title":"Addiction"},{"issue":"1","key":"10.1016\/j.drugalcdep.2007.05.021_bib19","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.taap.2004.08.008","article-title":"Free radical production induced by methamphetamine in rat striatal synaptosomes","volume":"204","author":"Pubill","year":"2005","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.drugalcdep.2007.05.021_bib20","series-title":"Techniques to Assess Alcohol Consumption","first-page":"19","article-title":"Timeline follow back: a technique for assessing self-reported ethanol consumption","author":"Sobell","year":"1992"},{"key":"10.1016\/j.drugalcdep.2007.05.021_bib21","first-page":"180","article-title":"The Substance Clinical Global Impression (SCGI) Scale: measuring global functioning in substance related clinical trials","author":"Tracy","year":"2000","journal-title":"NIDA Res. Monogr."},{"issue":"1","key":"10.1016\/j.drugalcdep.2007.05.021_bib22","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1016\/j.pharmthera.2005.06.010","article-title":"Medications development: successes and challenges","volume":"108","author":"Vocci","year":"2005","journal-title":"Pharmacol. Ther."},{"key":"10.1016\/j.drugalcdep.2007.05.021_bib23","doi-asserted-by":"crossref","first-page":"919","DOI":"10.1177\/003591577406700937","article-title":"Do antihypertensive drugs really cause depression?","volume":"67","author":"Wendy","year":"1974","journal-title":"J. R. Soc. Med."},{"key":"10.1016\/j.drugalcdep.2007.05.021_bib24","first-page":"81","article-title":"Reserpine: the maligned antihypertensive drug","volume":"20","author":"Widmer","year":"1985","journal-title":"J. Fam. Pract."},{"key":"10.1016\/j.drugalcdep.2007.05.021_bib25","doi-asserted-by":"crossref","first-page":"742","DOI":"10.1001\/archpsyc.1988.01800320058007","article-title":"A structured interview guide for the Hamilton Depression Rating Scale","volume":"45","author":"Williams","year":"1988","journal-title":"Arch. Gen. Psychiatry"}],"container-title":["Drug and Alcohol Dependence"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0376871607002311?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0376871607002311?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,8,19]],"date-time":"2021-08-19T04:12:55Z","timestamp":1629346375000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0376871607002311"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,12]]},"references-count":25,"journal-issue":{"issue":"2-3","published-print":{"date-parts":[[2007,12]]}},"alternative-id":["S0376871607002311"],"URL":"https:\/\/doi.org\/10.1016\/j.drugalcdep.2007.05.021","relation":{},"ISSN":["0376-8716"],"issn-type":[{"value":"0376-8716","type":"print"}],"subject":[],"published":{"date-parts":[[2007,12]]}}}