{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,27]],"date-time":"2025-09-27T03:33:42Z","timestamp":1758944022395},"reference-count":44,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2011,6,1]],"date-time":"2011-06-01T00:00:00Z","timestamp":1306886400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Drug and Alcohol Dependence"],"published-print":{"date-parts":[[2011,6]]},"DOI":"10.1016\/j.drugalcdep.2010.10.024","type":"journal-article","created":{"date-parts":[[2010,12,29]],"date-time":"2010-12-29T04:13:45Z","timestamp":1293596025000},"page":"183-189","source":"Crossref","is-referenced-by-count":10,"title":["Genetic moderators and psychiatric mediators of the link between sexual abuse and alcohol dependence"],"prefix":"10.1016","volume":"115","author":[{"given":"William E.","family":"Copeland","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u00c5sa","family":"Magnusson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mona","family":"G\u00f6ransson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Markus A.","family":"Heilig","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.drugalcdep.2010.10.024_bib0005","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1016\/j.drugalcdep.2005.11.024","article-title":"Association of an Asn40Asp (A118G) polymorphism in the [mu]-opioid receptor gene with substance dependence: a meta-analysis","volume":"83","author":"Arias","year":"2006","journal-title":"Drug Alcohol Depend."},{"key":"10.1016\/j.drugalcdep.2010.10.024_bib0010","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/0306-4603(89)90043-9","article-title":"Early detection of harmful alcohol consumption: comparison of clinical, laboratory, and self-report screening procedures","volume":"14","author":"Babor","year":"1989","journal-title":"Addict. Behav."},{"key":"10.1016\/j.drugalcdep.2010.10.024_bib0015","doi-asserted-by":"crossref","first-page":"1173","DOI":"10.1037\/0022-3514.51.6.1173","article-title":"The moderator\u2013mediator variable distinction in social psychological research: conceptual, strategic, and statistical considerations","volume":"51","author":"Baron","year":"1986","journal-title":"J. Pers. Soc. Psychol."},{"key":"10.1016\/j.drugalcdep.2010.10.024_bib0020","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1016\/j.biopsych.2007.04.026","article-title":"Interaction between CRHR1 gene and stressful life events predicts adolescent heavy alcohol use","volume":"63","author":"Blomeyer","year":"2008","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.drugalcdep.2010.10.024_bib0025","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1001\/archgenpsychiatry.2007.26","article-title":"Influence of child abuse on adult depression: moderation by the corticotropin-releasing hormone receptor gene","volume":"65","author":"Bradley","year":"2008","journal-title":"Arch. Gen. Psychiatry"},{"key":"10.1016\/j.drugalcdep.2010.10.024_bib0030","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1192\/bjp.179.5.444","article-title":"Features of childhood sexual abuse and the development of psychiatric and substance use disorders","volume":"179","author":"Bulik","year":"2001","journal-title":"Brit. J. Psychiatry"},{"key":"10.1016\/j.drugalcdep.2010.10.024_bib0035","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1017\/S0033291799001373","article-title":"Early sexual abuse and lifetime psychopathology: a co-twin-control study","volume":"30","author":"Dinwiddie","year":"2000","journal-title":"Psychol. Med."},{"key":"10.1016\/j.drugalcdep.2010.10.024_bib0040","doi-asserted-by":"crossref","first-page":"1696","DOI":"10.1111\/j.1360-0443.2006.01606.x","article-title":"Concurrent validity of the alcohol use disorders identification test (AUDIT) and AUDIT zones in defining levels of severity among out-patients with alcohol dependence in the COMBINE study","volume":"101","author":"Donovan","year":"2006","journal-title":"Addiction"},{"key":"10.1016\/j.drugalcdep.2010.10.024_bib0045","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1038\/sj.mp.4002034","article-title":"Interaction between a functional MAOA locus and childhood sexual abuse predicts alcoholism and antisocial personality disorder in adult women","volume":"13","author":"Ducci","year":"2007","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.drugalcdep.2010.10.024_bib0050","doi-asserted-by":"crossref","first-page":"985","DOI":"10.1080\/080352502760272704","article-title":"Sexual behaviour and early coitarche in a national sample of 17-year-old Swedish boys","volume":"91","author":"Edgardh","year":"2002","journal-title":"Acta Paediatr."},{"key":"10.1016\/j.drugalcdep.2010.10.024_bib0055","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/S0145-2134(97)00133-6","article-title":"PTSD as a mediator between childhood rape and alcohol use in adult women","volume":"22","author":"Epstein","year":"1998","journal-title":"Child Abuse Negl."},{"key":"10.1016\/j.drugalcdep.2010.10.024_bib0060","doi-asserted-by":"crossref","first-page":"1365","DOI":"10.1097\/00004583-199610000-00024","article-title":"Childhood sexual abuse and psychiatric disorder in young adulthood. II. Psychiatric outcomes of childhood sexual abuse","volume":"35","author":"Fergusson","year":"1996","journal-title":"J. Am. Acad. Child Adolesc. Psychiatry"},{"key":"10.1016\/j.drugalcdep.2010.10.024_bib0065","series-title":"Childhood Sexual Abuse: An Evidence based Perspective","author":"Fergusson","year":"1999"},{"key":"10.1016\/j.drugalcdep.2010.10.024_bib0070","series-title":"Structured Clinical Interview for DSM-IV Axis I Disorders (SCID-I), Clinician Version","author":"First","year":"1997"},{"key":"10.1016\/j.drugalcdep.2010.10.024_bib0075","doi-asserted-by":"crossref","first-page":"1513","DOI":"10.1046\/j.1360-0443.2003.00498.x","article-title":"Fetus at risk: prevalence of alcohol consumption during pregnancy estimated with a simple screening method in Swedish antenatal clinics","volume":"98","author":"G\u00f6ransson","year":"2003","journal-title":"Addiction"},{"key":"10.1016\/j.drugalcdep.2010.10.024_bib0085","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1177\/088626099014006006","article-title":"Adverse effect of child abuse victimization among substance-using women in treatment","volume":"14","author":"Kang","year":"1999","journal-title":"J. Interpers. Violence"},{"key":"10.1016\/j.drugalcdep.2010.10.024_bib0090","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1001\/archpsyc.57.10.953","article-title":"Childhood sexual abuse and adult psychiatric and substance use disorders in women: an epidemiological and cotwin control analysis","volume":"57","author":"Kendler","year":"2000","journal-title":"Arch. Gen. Psychiatry"},{"key":"10.1016\/j.drugalcdep.2010.10.024_bib0095","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1001\/archpsyc.1997.01830160031005","article-title":"Lifetime co-occurrence of DSM-III-R alcohol abuse and dependence with other psychiatric disorders in the national comorbidity survey","volume":"54","author":"Kessler","year":"1997","journal-title":"Arch. Gen. Psychiatry"},{"key":"10.1016\/j.drugalcdep.2010.10.024_bib0100","doi-asserted-by":"crossref","first-page":"1101","DOI":"10.1017\/S0033291797005588","article-title":"Childhood adversity and adult psychiatric disorder in the US National Comorbidity Survey","volume":"27","author":"Kessler","year":"1997","journal-title":"Psychol. Med."},{"key":"10.1016\/j.drugalcdep.2010.10.024_bib0105","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1037\/0022-006X.68.1.19","article-title":"Risk factors for adolescent substance abuse and dependence: data from a national sample","volume":"68","author":"Kilpatrick","year":"2000","journal-title":"J. Consult. Clin. Psychol."},{"key":"10.1016\/j.drugalcdep.2010.10.024_bib0110","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1038\/sj.mp.4001851","article-title":"MAOA, maltreatment, and gene-environment interaction predicting children's mental health: new evidence and a meta-analysis","volume":"11","author":"Kim-Cohen","year":"2006","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.drugalcdep.2010.10.024_bib0115","series-title":"Sex in Sweden. On the Swedish Sexual Life","author":"Lewin","year":"1997"},{"key":"10.1016\/j.drugalcdep.2010.10.024_bib0120","doi-asserted-by":"crossref","first-page":"131","DOI":"10.2307\/353667","article-title":"Sexual abuse history and problems in adolescence: exploring the effects of moderating variables","volume":"59","author":"Luster","year":"1997","journal-title":"J. Marriage Family"},{"key":"10.1016\/j.drugalcdep.2010.10.024_bib0125","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1037\/1082-989X.7.1.83","article-title":"A comparison of methods to test mediation and other intervening variable effects","volume":"7","author":"MacKinnon","year":"2002","journal-title":"Psychol. Meth."},{"key":"10.1016\/j.drugalcdep.2010.10.024_bib0135","doi-asserted-by":"crossref","first-page":"1362","DOI":"10.1001\/jama.277.17.1362","article-title":"Clinical characteristics of women with a history of childhood abuse: unhealed wounds","volume":"277","author":"McCauley","year":"1997","journal-title":"JAMA"},{"key":"10.1016\/j.drugalcdep.2010.10.024_bib0140","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1097\/00005053-198001000-00006","article-title":"An improved diagnostic evaluation instrument for substance abuse patients: the Addiction Severity Index","volume":"168","author":"McLellan","year":"1980","journal-title":"J. Nerv. Ment. Dis."},{"key":"10.1016\/j.drugalcdep.2010.10.024_bib0145","doi-asserted-by":"crossref","first-page":"753","DOI":"10.2105\/AJPH.91.5.753","article-title":"Child sexual abuse and subsequent psychopathology: results from the national comorbidity survey","volume":"91","author":"Molnar","year":"2001","journal-title":"Am. J. Public Health"},{"key":"10.1016\/j.drugalcdep.2010.10.024_bib0150","doi-asserted-by":"crossref","first-page":"592","DOI":"10.1093\/alcalc\/33.6.592","article-title":"Sexual abuse and the subsequent development of alcohol problems","volume":"33","author":"Moncrieff","year":"1998","journal-title":"Alcohol Alcohol."},{"key":"10.1016\/j.drugalcdep.2010.10.024_bib0155","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1192\/bjp.163.6.721","article-title":"Childhood sexual abuse and mental health in adult life","volume":"163","author":"Mullen","year":"1993","journal-title":"Brit. J. Psychiatry"},{"key":"10.1016\/j.drugalcdep.2010.10.024_bib0160","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1369-1600.2009.00181.x","article-title":"H2 haplotype at chromosome 17q21.31 protects against childhood sexual abuse-associated risk for alcohol consumption and dependence","volume":"15","author":"Nelson","year":"2010","journal-title":"Addict. Biol."},{"key":"10.1016\/j.drugalcdep.2010.10.024_bib0165","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.drugalcdep.2007.08.022","article-title":"The MAO-A gene, platelet MAO-B activity and psychosocial environment in adolescent female alcohol-related problem behaviour","volume":"93","author":"Nilsson","year":"2008","journal-title":"Drug Alcohol Depend."},{"key":"10.1016\/j.drugalcdep.2010.10.024_bib0170","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.drugalcdep.2004.09.005","article-title":"Prevalence of physical and sexual abuse among substance abuse patients and impact on treatment outcomes","volume":"78","author":"Pirard","year":"2005","journal-title":"Drug Alcohol Depend."},{"key":"10.1016\/j.drugalcdep.2010.10.024_bib0175","first-page":"103","article-title":"A functional polymorphism in the monoamine oxidase A gene promoter","author":"Sabol","year":"1998","journal-title":"J. Human Genet."},{"key":"10.1016\/j.drugalcdep.2010.10.024_bib0180","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/j.drugalcdep.2006.12.022","article-title":"Childhood sexual abuse and the course of alcohol dependence development: findings from a female twin sample","volume":"89","author":"Sartor","year":"2007","journal-title":"Drug Alcohol Depend."},{"key":"10.1016\/j.drugalcdep.2010.10.024_bib0185","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1111\/j.1360-0443.1993.tb02093.x","article-title":"Development of the alcohol use disorders identification test (AUDIT). WHO collaborative project on early detection of persons with harmful alcohol consumption II","volume":"88","author":"Saunders","year":"1993","journal-title":"Addiction"},{"key":"10.1016\/j.drugalcdep.2010.10.024_bib0190","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1016\/j.drugalcdep.2009.06.020","article-title":"What are the needs of alcohol dependent patients with a history of sexual violence? A case-register study in a metropolitan region","volume":"105","author":"Sch\u00e4fer","year":"2009","journal-title":"Drug Alcohol Depend."},{"key":"10.1016\/j.drugalcdep.2010.10.024_bib0195","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/S0272-7358(00)00088-X","article-title":"Concomitance between childhood sexual and physical abuse and substance use problems: a review","volume":"22","author":"Simpson","year":"2002","journal-title":"Clin. Psychol. Rev."},{"key":"10.1016\/j.drugalcdep.2010.10.024_bib0200","doi-asserted-by":"crossref","first-page":"1312","DOI":"10.1111\/j.1530-0277.2000.tb02097.x","article-title":"Alcohol and eating disorders: implications for alcohol treatment and health services research","volume":"24","author":"Sinha","year":"2000","journal-title":"Alcohol. Clin. Exp. Res."},{"key":"10.1016\/j.drugalcdep.2010.10.024_bib0205","doi-asserted-by":"crossref","first-page":"290","DOI":"10.2307\/270723","article-title":"Asymptomic confidence intervals for indirect effects in structural equation models","author":"Sobel","year":"1982","journal-title":"Sociol. Methodol."},{"key":"10.1016\/j.drugalcdep.2010.10.024_bib0210","series-title":"Measuring Alcohol Consumption: Psychosocial and Biochemical Methods","first-page":"41","article-title":"Timeline follow-back: a technique for assessing self-reported alcohol consumption. Measuring alcohol consumption: psychosocial and biochemical methods","author":"Sobell","year":"1992"},{"key":"10.1016\/j.drugalcdep.2010.10.024_bib0215","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/S1054-139X(98)00112-8","article-title":"Self-reported abuse history and adolescent problem behaviors. II. Alcohol and drug use","volume":"24","author":"Southwick Bensley","year":"1999","journal-title":"J. Adolesc. Health"},{"key":"10.1016\/j.drugalcdep.2010.10.024_bib0220","doi-asserted-by":"crossref","first-page":"1365","DOI":"10.1046\/j.1360-0443.1998.93913657.x","article-title":"Sexual abuse and alcoholism in a female population","volume":"93","author":"Spak","year":"1998","journal-title":"Addiction"},{"key":"10.1016\/j.drugalcdep.2010.10.024_bib0225","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1080\/10550490701643484","article-title":"Differences in early onset alcohol use and heavy drinking among persons with childhood and adulthood trauma","volume":"16","author":"Waldrop","year":"2007","journal-title":"Am. J. Addict."},{"key":"10.1016\/j.drugalcdep.2010.10.024_bib0230","doi-asserted-by":"crossref","first-page":"1211","DOI":"10.1017\/S0033291703008158","article-title":"Primary anxiety disorders and the development of subsequent alcohol use disorders: a 4-year community study of adolescents and young adults","volume":"33","author":"Zimmermann","year":"2003","journal-title":"Psychol. Med."}],"container-title":["Drug and Alcohol Dependence"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S037687161000400X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S037687161000400X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,12,5]],"date-time":"2018-12-05T20:20:08Z","timestamp":1544041208000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S037687161000400X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,6]]},"references-count":44,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2011,6]]}},"alternative-id":["S037687161000400X"],"URL":"https:\/\/doi.org\/10.1016\/j.drugalcdep.2010.10.024","relation":{},"ISSN":["0376-8716"],"issn-type":[{"value":"0376-8716","type":"print"}],"subject":[],"published":{"date-parts":[[2011,6]]}}}