{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T00:35:27Z","timestamp":1792197327006,"version":"4.4.0"},"reference-count":208,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100018537","name":"National Science and Technology Major Project","doi-asserted-by":"publisher","award":["2019ZX09301-147"],"award-info":[{"award-number":["2019ZX09301-147"]}],"id":[{"id":"10.13039\/501100018537","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82574693"],"award-info":[{"award-number":["82574693"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81960769"],"award-info":[{"award-number":["81960769"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31971308"],"award-info":[{"award-number":["31971308"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Drug Resistance Updates"],"published-print":{"date-parts":[[2026,3]]},"DOI":"10.1016\/j.drup.2025.101345","type":"journal-article","created":{"date-parts":[[2025,12,25]],"date-time":"2025-12-25T00:14:51Z","timestamp":1766621691000},"page":"101345","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"special_numbering":"C","title":["Overcoming resistance in oncolytic virotherapy: Nano-engineered solutions for systemic delivery and efficacy boost"],"prefix":"10.1016","volume":"85","author":[{"given":"Xiaoxiao","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rangrang","family":"Fan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Geyuan","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bo","family":"Han","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liangxue","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aiping","family":"Tong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bingwen","family":"Zou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4440-6366","authenticated-orcid":false,"given":"Gang","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.drup.2025.101345_bib1","doi-asserted-by":"crossref","first-page":"3829","DOI":"10.1200\/JCO.20.03246","article-title":"Clinical responses of oncolytic coxsackievirus A21 (V937) in patients with unresectable melanoma","volume":"39","author":"Andtbacka","year":"2021","journal-title":"J. Clin. Oncol."},{"key":"10.1016\/j.drup.2025.101345_bib2","doi-asserted-by":"crossref","first-page":"2780","DOI":"10.1200\/JCO.2014.58.3377","article-title":"Talimogene laherparepvec improves durable response rate in patients with advanced melanoma","volume":"33","author":"Andtbacka","year":"2015","journal-title":"J. Clin. Oncol."},{"key":"10.1016\/j.drup.2025.101345_bib3","doi-asserted-by":"crossref","DOI":"10.1136\/jitc-2024-009443","article-title":"Combination of oncolytic Maraba virus with immune checkpoint blockade overcomes therapy resistance in an immunologically cold model of advanced melanoma with dysfunctional T-cell receptor signalling","volume":"12","author":"Armstrong","year":"2024","journal-title":"J. Immunother. Cancer"},{"key":"10.1016\/j.drup.2025.101345_bib4","doi-asserted-by":"crossref","first-page":"4241","DOI":"10.1021\/acsnano.3c09491","article-title":"Synergistic viro-chemoimmunotherapy in breast cancer enabled by bioengineered immunostimulatory exosomes and dual-targeted coxsackievirus B3","volume":"18","author":"Bahreyni","year":"2024","journal-title":"ACS Nano"},{"key":"10.1016\/j.drup.2025.101345_bib5","doi-asserted-by":"crossref","first-page":"4137","DOI":"10.1007\/s12274-021-4031-6","article-title":"Emerging systemic delivery strategies of oncolytic viruses: a key step toward cancer immunotherapy","volume":"15","author":"Ban","year":"2022","journal-title":"Nano Res"},{"key":"10.1016\/j.drup.2025.101345_bib6","doi-asserted-by":"crossref","first-page":"2933","DOI":"10.1038\/s41467-023-38679-z","article-title":"Engineered bacterial outer membrane vesicles encapsulating oncolytic adenoviruses enhance the efficacy of cancer virotherapy by augmenting tumor cell autophagy","volume":"14","author":"Ban","year":"2023","journal-title":"Nat. Commun."},{"key":"10.1016\/j.drup.2025.101345_bib7","doi-asserted-by":"crossref","first-page":"2744","DOI":"10.7150\/thno.40902","article-title":"Oligopeptide-modified poly(beta-amino ester)s-coated AdNuPARmE1A: boosting the efficacy of intravenously administered therapeutic adenoviruses","volume":"10","author":"Brugada-Vil\u00e0","year":"2020","journal-title":"Theranostics"},{"key":"10.1016\/j.drup.2025.101345_bib8","doi-asserted-by":"crossref","DOI":"10.1016\/j.drup.2025.101277","article-title":"Engineering nanoplatforms of bacterial outer membrane vesicles to overcome cancer therapy resistance","volume":"83","author":"Chai","year":"2025","journal-title":"Drug Resist Update"},{"key":"10.1016\/j.drup.2025.101345_bib9","first-page":"1","article-title":"An oncolytic virus\u2013T cell chimera for cancer immunotherapy","author":"Chen","year":"2024","journal-title":"Nat. Biotechnol."},{"key":"10.1016\/j.drup.2025.101345_bib10","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/j.canlet.2021.09.040","article-title":"Stereotactic body radiation combined with oncolytic vaccinia virus induces potent anti-tumor effect by triggering tumor cell necroptosis and DAMPs","volume":"523","author":"Chen","year":"2021","journal-title":"Cancer Lett."},{"key":"10.1016\/j.drup.2025.101345_bib11","article-title":"Less is more: biomimetic hybrid membrane nanocarriers for highly efficient tumor targeted drug delivery","volume":"21","author":"Chen","year":"2025","journal-title":"Small"},{"key":"10.1016\/j.drup.2025.101345_bib12","article-title":"Integrated design of a membrane-lytic peptide-based intravenous nanotherapeutic suppresses triple-negative breast cancer","volume":"9","author":"Chen","year":"2022","journal-title":"Adv. Sci."},{"key":"10.1016\/j.drup.2025.101345_bib13","article-title":"Micro-to-nano oncolytic microbial system shifts from tumor killing to tumor draining lymph nodes remolding for enhanced immunotherapy","volume":"36","author":"Chen","year":"2024","journal-title":"Adv. Mater."},{"key":"10.1016\/j.drup.2025.101345_bib14","doi-asserted-by":"crossref","first-page":"20296","DOI":"10.1021\/acsnano.4c04045","article-title":"Ultrasound-activatable in situ vaccine for enhanced antigen self- and cross-presentation to overcome cancer immunotherapy resistance","volume":"18","author":"Chen","year":"2024","journal-title":"ACS Nano"},{"key":"10.1016\/j.drup.2025.101345_bib15","doi-asserted-by":"crossref","first-page":"10147","DOI":"10.1021\/acsnano.4c17148","article-title":"Boosting peroxidase-mimetic activity of FeMn-NCe dual-atom radiosensitizing nanozymes for augmented radiodynamic immunotherapy","volume":"19","author":"Chen","year":"2025","journal-title":"ACS Nano"},{"key":"10.1016\/j.drup.2025.101345_bib16","doi-asserted-by":"crossref","first-page":"3741","DOI":"10.1039\/D3TB03016D","article-title":"Enhancing oncolytic virus efficiency with methionine and N-(3-aminoprolil)methacrylamide modified acrylamide cationic block polymer","volume":"12","author":"Chen","year":"2024","journal-title":"J. Mater. Chem. B"},{"key":"10.1016\/j.drup.2025.101345_bib17","first-page":"598","article-title":"Anti-EpCAM functionalized graphene oxide vector for tumor targeted siRNA delivery and cancer therapy","volume":"16","author":"Chen","year":"2021","journal-title":"Asian J. Pharm. Sci."},{"key":"10.1016\/j.drup.2025.101345_bib18","article-title":"Cascade-type microglial pyroptosis inhibitors for enhanced treatment of cerebral ischemia-reperfusion injury","author":"Cheng","year":"2025","journal-title":"ACS Nano"},{"key":"10.1016\/j.drup.2025.101345_bib19","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/j.actbio.2015.09.014","article-title":"Enhanced anti-tumor efficacy and safety profile of tumor microenvironment-responsive oncolytic adenovirus nanocomplex by systemic administration","volume":"28","author":"Choi","year":"2015","journal-title":"Acta Biomater."},{"key":"10.1016\/j.drup.2025.101345_bib20","doi-asserted-by":"crossref","first-page":"9934","DOI":"10.1038\/s41467-024-54293-z","article-title":"Urease-powered nanomotor containing STING agonist for bladder cancer immunotherapy","volume":"15","author":"Choi","year":"2024","journal-title":"Nat. Commun."},{"key":"10.1016\/j.drup.2025.101345_bib21","first-page":"134","article-title":"pH-Sensitive oncolytic adenovirus hybrid targeting acidic tumor microenvironment and angiogenesis","volume":"205","author":"Choi","year":"2015","journal-title":"J. Control. Release 3rd Symp Innov. Polym. Control. Deliv. (SIPCD 2014)"},{"key":"10.1016\/j.drup.2025.101345_bib22","doi-asserted-by":"crossref","first-page":"973","DOI":"10.1016\/j.ccell.2021.05.006","article-title":"Tim-4+ cavity-resident macrophages impair anti-tumor CD8+ T cell immunity","volume":"39","author":"Chow","year":"2021","journal-title":"Cancer Cell"},{"key":"10.1016\/j.drup.2025.101345_bib23","doi-asserted-by":"crossref","DOI":"10.1002\/adma.202201042","article-title":"Magnetic-powered janus cell robots loaded with oncolytic adenovirus for active and targeted virotherapy of bladder cancer","volume":"34","author":"Cong","year":"2022","journal-title":"Adv. Mater."},{"key":"10.1016\/j.drup.2025.101345_bib24","doi-asserted-by":"crossref","first-page":"33181","DOI":"10.1021\/acsnano.4c11805","article-title":"Assessing therapeutic nanoparticle accumulation in tumors using nanobubble-based contrast-enhanced ultrasound imaging","volume":"18","author":"Cooley","year":"2024","journal-title":"ACS Nano"},{"key":"10.1016\/j.drup.2025.101345_bib25","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1016\/j.jconrel.2024.02.037","article-title":"Smart exosomes enhance PDAC targeted therapy","volume":"368","author":"Creeden","year":"2024","journal-title":"J. Control Release"},{"key":"10.1016\/j.drup.2025.101345_bib26","article-title":"Oncolytic virus M1 functions as a bifunctional checkpoint inhibitor to enhance the antitumor activity of DC vaccine","volume":"4","author":"Dan","year":"2023","journal-title":"Cell Rep. Med."},{"key":"10.1016\/j.drup.2025.101345_bib27","doi-asserted-by":"crossref","DOI":"10.1136\/jitc-2024-009336","article-title":"Phase I study of a recombinant attenuated oncolytic virus, MEDI5395 (NDV-GM-CSF), administered systemically in combination with durvalumab in patients with advanced solid tumors","volume":"12","author":"Davar","year":"2024","journal-title":"J. Immunother. Cancer"},{"key":"10.1016\/j.drup.2025.101345_bib28","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1016\/j.jtho.2019.12.128","article-title":"Frequent homozygous deletions of type I interferon genes in pleural mesothelioma confer sensitivity to oncolytic measles virus","volume":"15","author":"Delaunay","year":"2020","journal-title":"J. Thorac. Oncol."},{"key":"10.1016\/j.drup.2025.101345_bib29","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/j.trecan.2023.09.012","article-title":"Integrating innate and adaptive immunity in oncolytic virus therapy","volume":"10","author":"DePeaux","year":"2024","journal-title":"Trends Cancer"},{"key":"10.1016\/j.drup.2025.101345_bib30","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1016\/j.jconrel.2021.12.018","article-title":"RBC-hitchhiking chitosan nanoparticles loading methylprednisolone for lung-targeting delivery","volume":"341","author":"Ding","year":"2022","journal-title":"J. Control Release"},{"key":"10.1016\/j.drup.2025.101345_bib31","doi-asserted-by":"crossref","DOI":"10.1186\/s12967-025-07500-4","article-title":"Multi-omics analysis reveals the association between intratumoral bacteria and somatic mutational signatures in oral squamous cell carcinoma","author":"Dong","year":"2025","journal-title":"J. Transl. Med."},{"key":"10.1016\/j.drup.2025.101345_bib32","doi-asserted-by":"crossref","first-page":"975","DOI":"10.1089\/hum.2009.028","article-title":"Chemical modification with high molecular weight polyethylene glycol reduces transduction of hepatocytes and increases efficacy of intravenously delivered oncolytic adenovirus","volume":"20","author":"Doronin","year":"2009","journal-title":"Hum. Gene Ther."},{"key":"10.1016\/j.drup.2025.101345_bib33","doi-asserted-by":"crossref","first-page":"1356","DOI":"10.1186\/s12967-025-07390-6","article-title":"Spatial omics in 3D culture model systems: decoding cellular positioning mechanisms and microenvironmental dynamics","volume":"23","author":"Du","year":"2025","journal-title":"J. Transl. Med"},{"key":"10.1016\/j.drup.2025.101345_bib34","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1038\/s41591-024-03411-x","article-title":"Neoadjuvant anti-PD-1 alone or in combination with anti-TIGIT or an oncolytic virus in resectable stage IIIB\u2013D melanoma: a phase 1\/2 trial","volume":"31","author":"Dummer","year":"2025","journal-title":"Nat. Med"},{"key":"10.1016\/j.drup.2025.101345_bib35","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.jconrel.2022.12.050","article-title":"Pre-treatment of oncolytic reovirus improves tumor accumulation and intratumoral distribution of PEG-liposomes","volume":"354","author":"Eguchi","year":"2023","journal-title":"J. Control Release"},{"key":"10.1016\/j.drup.2025.101345_bib36","doi-asserted-by":"crossref","DOI":"10.1126\/scitranslmed.abn2231","article-title":"Oncolytic virus\u2013mediated expansion of dual-specific CAR T cells improves efficacy against solid tumors in mice","volume":"14","author":"Evgin","year":"2022","journal-title":"Sci. Transl. Med."},{"key":"10.1016\/j.drup.2025.101345_bib37","doi-asserted-by":"crossref","first-page":"12824","DOI":"10.1021\/acsami.0c16576","article-title":"pH-Sensitive nanoparticles composed solely of membrane-disruptive macromolecules for treating pancreatic cancer","volume":"13","author":"Fan","year":"2021","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"10.1016\/j.drup.2025.101345_bib38","doi-asserted-by":"crossref","DOI":"10.1093\/nsr\/nwae368","article-title":"Fossil evidence for silica biomineralization in permian lycophytes","volume":"11","author":"Feng","year":"2024","journal-title":"Natl. Sci. Rev."},{"key":"10.1016\/j.drup.2025.101345_bib39","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1016\/j.jcis.2021.06.047","article-title":"Protein corona modulates interaction of spiky nanoparticles with lipid bilayers","volume":"603","author":"Fleury","year":"2021","journal-title":"J. Colloid Inter. Sci."},{"key":"10.1016\/j.drup.2025.101345_bib40","doi-asserted-by":"crossref","first-page":"1613","DOI":"10.1056\/NEJMoa2024947","article-title":"Oncolytic HSV-1 G207 immunovirotherapy for pediatric high-grade gliomas","volume":"384","author":"Friedman","year":"2021","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.drup.2025.101345_bib41","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41392-024-01824-1","article-title":"Combination therapy with oncolytic virus and T cells or mRNA vaccine amplifies antitumor effects","volume":"9","author":"Fu","year":"2024","journal-title":"Sig Transduct. Target Ther."},{"key":"10.1016\/j.drup.2025.101345_bib42","doi-asserted-by":"crossref","first-page":"5747","DOI":"10.1038\/s41467-019-13744-8","article-title":"Artificially cloaked viral nanovaccine for cancer immunotherapy","volume":"10","author":"Fusciello","year":"2019","journal-title":"Nat. Commun."},{"key":"10.1016\/j.drup.2025.101345_bib43","doi-asserted-by":"crossref","first-page":"2471","DOI":"10.1056\/NEJMoa2202028","article-title":"Oncolytic DNX-2401 virus for pediatric diffuse intrinsic pontine glioma","volume":"386","author":"G\u00e1llego P\u00e9rez-Larraya","year":"2022","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.drup.2025.101345_bib44","doi-asserted-by":"crossref","first-page":"2471","DOI":"10.1056\/NEJMoa2202028","article-title":"Oncolytic DNX-2401 virus for pediatric diffuse intrinsic pontine glioma","volume":"386","author":"G\u00e1llego P\u00e9rez-Larraya","year":"2022","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.drup.2025.101345_bib45","doi-asserted-by":"crossref","first-page":"3576","DOI":"10.1007\/s11426-023-1841-8","article-title":"Polymer-based synthetic oncolytic virus-like nanoparticles for cancer immunotherapy","volume":"66","author":"Gao","year":"2023","journal-title":"Sci. China Chem."},{"key":"10.1016\/j.drup.2025.101345_bib46","doi-asserted-by":"crossref","DOI":"10.1136\/jitc-2021-003255","article-title":"Phase I, multicenter, open-label study of intravenous VCN-01 oncolytic adenovirus with or without nab-paclitaxel plus gemcitabine in patients with advanced solid tumors","volume":"10","author":"Garcia-Carbonero","year":"2022","journal-title":"J. Immunother. Cancer"},{"key":"10.1016\/j.drup.2025.101345_bib47","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/j.jconrel.2018.05.015","article-title":"Antitumor effect of oncolytic virus and paclitaxel encapsulated in extracellular vesicles for lung cancer treatment","volume":"283","author":"Garofalo","year":"2018","journal-title":"J. Control. Release"},{"key":"10.1016\/j.drup.2025.101345_bib48","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/j.jconrel.2018.12.022","article-title":"Extracellular vesicles enhance the targeted delivery of immunogenic oncolytic adenovirus and paclitaxel in immunocompetent mice","volume":"294","author":"Garofalo","year":"2019","journal-title":"J. Control. Release"},{"issue":"25","key":"10.1016\/j.drup.2025.101345_bib49","first-page":"00164","article-title":"Engineered platelets-based nano-aircraft system for precise tumor chemo-immunotherapy with graded drug delivery and self-recognized tumor targeting","volume":"S2095-9273","author":"Geng","year":"2025","journal-title":"Sci. Bull."},{"key":"10.1016\/j.drup.2025.101345_bib50","doi-asserted-by":"crossref","DOI":"10.1016\/j.biomaterials.2024.122870","article-title":"Tumor microenvironment-activated polypeptide nanoparticles for oncolytic immunotherapy","volume":"314","author":"Guo","year":"2025","journal-title":"Biomaterials"},{"key":"10.1016\/j.drup.2025.101345_bib51","doi-asserted-by":"crossref","first-page":"2121","DOI":"10.1021\/acsbiomaterials.2c00181","article-title":"Cationic amphiphilic dendrons with anticancer activity","volume":"8","author":"Guo","year":"2022","journal-title":"ACS Biomater. Sci. Eng."},{"key":"10.1016\/j.drup.2025.101345_bib52","article-title":"Decomposable nanoagonists enable NIR-elicited cGAS-STING activation for tandem-amplified photodynamic-metalloimmunotherapy","volume":"36","author":"Guo","year":"2024","journal-title":"Adv. Mater."},{"key":"10.1016\/j.drup.2025.101345_bib53","doi-asserted-by":"crossref","first-page":"3435","DOI":"10.1038\/s41467-024-47696-5","article-title":"Exosome-coated oxygen nanobubble-laden hydrogel augments intracellular delivery of exosomes for enhanced wound healing","volume":"15","author":"Han","year":"2024","journal-title":"Nat. Commun."},{"key":"10.1016\/j.drup.2025.101345_bib54","doi-asserted-by":"crossref","DOI":"10.1002\/adma.202000208","article-title":"Aptamer\/peptide-functionalized genome-editing system for effective immune restoration through reversal of PD-L1-mediated cancer immunosuppression","volume":"32","author":"He","year":"2020","journal-title":"Adv. Mater."},{"key":"10.1016\/j.drup.2025.101345_bib55","doi-asserted-by":"crossref","DOI":"10.1002\/smll.202104763","article-title":"Nanobugs as drugs: bacterial derived nanomagnets enhance tumor targeting and oncolytic activity of HSV-1 virus","volume":"18","author":"Howard","year":"2022","journal-title":"Small"},{"key":"10.1016\/j.drup.2025.101345_bib56","doi-asserted-by":"crossref","first-page":"1497","DOI":"10.1038\/mt.2015.110","article-title":"Mesenchymal stromal cells for linked delivery of oncolytic and apoptotic adenoviruses to non-small-cell lung cancers","volume":"23","author":"Hoyos","year":"2015","journal-title":"Mol. Ther."},{"key":"10.1016\/j.drup.2025.101345_bib57","doi-asserted-by":"crossref","first-page":"1038","DOI":"10.1038\/s41551-021-00712-1","article-title":"Inhibition of post-surgery tumour recurrence via a hydrogel releasing CAR-T cells and anti-PDL1-conjugated platelets","volume":"5","author":"Hu","year":"2021","journal-title":"Nat. Biomed. Eng."},{"key":"10.1016\/j.drup.2025.101345_bib58","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1016\/j.jcis.2024.05.175","article-title":"Platelet membrane-coated oncolytic vaccinia virus with indocyanine green for the second near-infrared imaging guided multi-modal therapy of colorectal cancer","volume":"671","author":"Huang","year":"2024","journal-title":"J. Colloid Inter. Sci."},{"key":"10.1016\/j.drup.2025.101345_bib59","doi-asserted-by":"crossref","first-page":"8002","DOI":"10.1021\/acs.nanolett.9b03193","article-title":"MnCaCs-Biomineralized oncolytic virus for bimodal imaging-guided and synergistically enhanced anticancer therapy","volume":"19","author":"Huang","year":"2019","journal-title":"Nano Lett."},{"key":"10.1016\/j.drup.2025.101345_bib60","article-title":"MMP9-responsive graphene oxide quantum dot-based nano-in-micro drug delivery system for combinatorial therapy of choroidal neovascularization","volume":"19","author":"Huang","year":"2023","journal-title":"Small"},{"key":"10.1016\/j.drup.2025.101345_bib61","doi-asserted-by":"crossref","first-page":"14461","DOI":"10.1021\/acsnano.3c00847","article-title":"Virus-protein corona replacement strategy to improve the antitumor efficacy of intravenously injected oncolytic adenovirus","volume":"17","author":"Huang","year":"2023","journal-title":"ACS Nano"},{"key":"10.1016\/j.drup.2025.101345_bib62","doi-asserted-by":"crossref","DOI":"10.1016\/j.nantod.2022.101671","article-title":"Full encapsulation of oncolytic virus using hybrid erythroctye-liposome membranes for augmented anti-refractory tumor effectiveness","volume":"47","author":"Huang","year":"2022","journal-title":"Nano Today"},{"key":"10.1016\/j.drup.2025.101345_bib63","doi-asserted-by":"crossref","first-page":"5033","DOI":"10.1021\/acsnano.2c12840","article-title":"Multiscale NIR-II imaging-guided brain-targeted drug delivery using engineered cell membrane nanoformulation for alzheimer\u2019s disease therapy","volume":"17","author":"Huang","year":"2023","journal-title":"ACS Nano"},{"key":"10.1016\/j.drup.2025.101345_bib64","doi-asserted-by":"crossref","DOI":"10.1016\/j.nano.2021.102506","article-title":"Targeting circulating monocytes with CCL2-loaded liposomes armed with an oncolytic adenovirus","volume":"40","author":"Iscaro","year":"2022","journal-title":"Nanomed. Nanotechnol. Biol. Med."},{"key":"10.1016\/j.drup.2025.101345_bib65","doi-asserted-by":"crossref","first-page":"11120","DOI":"10.1021\/acs.nanolett.3c03516","article-title":"Cell membrane-coated oncolytic adenovirus for targeted treatment of glioblastoma","volume":"23","author":"Jia","year":"2023","journal-title":"Nano Lett."},{"key":"10.1016\/j.drup.2025.101345_bib66","article-title":"Living microalgae-based magnetic microrobots for calcium overload and photodynamic synergetic cancer therapy","author":"Jiang","year":"2025","journal-title":"Adv. Health Mater."},{"key":"10.1016\/j.drup.2025.101345_bib67","article-title":"Recent advances in the development of tumor microenvironment-activatable nanomotors for deep tumor penetration","volume":"27","author":"Jiang","year":"2024","journal-title":"Mater. Today Bio"},{"key":"10.1016\/j.drup.2025.101345_bib68","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1186\/s12951-024-02414-7","article-title":"Anti-EGFR ScFv functionalized exosomes delivering LPCAT1 specific siRNAs for inhibition of lung cancer brain metastases","volume":"22","author":"Jiang","year":"2024","journal-title":"J. Nanobiotechnol."},{"key":"10.1016\/j.drup.2025.101345_bib69","article-title":"Disrupting intracellular homeostasis by copper-based nanoinducer with multiple enzyme-mimicking activities to induce disulfidptosis-enhanced pyroptosis for tumor immunotherapy","volume":"37","author":"Jin","year":"2025","journal-title":"Adv. Mater."},{"key":"10.1016\/j.drup.2025.101345_bib70","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1186\/s13046-024-03219-0","article-title":"Single intravenous administration of oncolytic adenovirus TILT-123 results in systemic tumor transduction and immune response in patients with advanced solid tumors","volume":"43","author":"Jirovec","year":"2024","journal-title":"J. Exp. Clin. Cancer Res."},{"key":"10.1016\/j.drup.2025.101345_bib71","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1038\/nature22341","article-title":"Exosomes facilitate therapeutic targeting of oncogenic KRAS in pancreatic cancer","volume":"546","author":"Kamerkar","year":"2017","journal-title":"Nature"},{"key":"10.1016\/j.drup.2025.101345_bib72","doi-asserted-by":"crossref","first-page":"5907","DOI":"10.1038\/s41467-022-33599-w","article-title":"Development of intravenously administered synthetic RNA virus immunotherapy for the treatment of cancer","volume":"13","author":"Kennedy","year":"2022","journal-title":"Nat. Commun."},{"key":"10.1016\/j.drup.2025.101345_bib73","article-title":"Poly(cyclodextrin)-polydrug nanocomplexes as synthetic oncolytic virus for locoregional melanoma chemoimmunotherapy","volume":"30","author":"Kim","year":"2020","journal-title":"Adv. Funct. Mater."},{"key":"10.1016\/j.drup.2025.101345_bib74","doi-asserted-by":"crossref","DOI":"10.1002\/adma.202310731","article-title":"Ultrasmall polyphenol-NAD+ nanoparticle-mediated renal delivery for mitochondrial repair and anti-inflammatory treatment of AKI-to-CKD progression","volume":"36","author":"Kong","year":"2024","journal-title":"Adv. Mater."},{"key":"10.1016\/j.drup.2025.101345_bib75","doi-asserted-by":"crossref","first-page":"5317","DOI":"10.1039\/D0BM00681E","article-title":"Biosilicified oncolytic adenovirus for cancer viral gene therapy","volume":"8","author":"Kong","year":"2020","journal-title":"Biomater. Sci."},{"key":"10.1016\/j.drup.2025.101345_bib76","doi-asserted-by":"crossref","DOI":"10.1016\/j.drup.2021.100787","article-title":"Hypoxia as a driver of resistance to immunotherapy","volume":"59","author":"Kopecka","year":"2021","journal-title":"Drug Resist. Updates"},{"key":"10.1016\/j.drup.2025.101345_bib77","doi-asserted-by":"crossref","first-page":"1930","DOI":"10.1038\/s41467-021-22115-1","article-title":"Oncolytic virotherapy induced CSDE1 neo-antigenesis restricts VSV replication but can be targeted by immunotherapy","volume":"12","author":"Kottke","year":"2021","journal-title":"Nat. Commun."},{"key":"10.1016\/j.drup.2025.101345_bib78","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2023.1175535","article-title":"CD44 targeted delivery of oncolytic Newcastle disease virus encapsulated in thiolated chitosan for sustained release in cervical cancer: a targeted immunotherapy approach","volume":"14","author":"Kousar","year":"2023","journal-title":"Front. Immunol."},{"key":"10.1016\/j.drup.2025.101345_bib79","doi-asserted-by":"crossref","first-page":"6299","DOI":"10.1038\/s41467-025-61297-w","article-title":"The PARP inhibitor talazoparib synergizes with reovirus to induce cancer killing and tumour control in vivo in mouse models","volume":"16","author":"Kyula-Currie","year":"2025","journal-title":"Nat. Commun."},{"key":"10.1016\/j.drup.2025.101345_bib80","doi-asserted-by":"crossref","first-page":"1419","DOI":"10.1200\/JCO.2017.75.8219","article-title":"Phase I study of DNX-2401 (delta-24-RGD) oncolytic adenovirus: replication and immunotherapeutic effects in recurrent malignant glioma","volume":"36","author":"Lang","year":"2018","journal-title":"J. Clin. Oncol."},{"key":"10.1016\/j.drup.2025.101345_bib81","doi-asserted-by":"crossref","first-page":"13214","DOI":"10.1021\/acsnano.4c02130","article-title":"Rational design of 3D polymer corona interfaces of single-walled carbon nanotubes for receptor-free virus recognition","volume":"18","author":"Lee","year":"2024","journal-title":"ACS Nano"},{"key":"10.1016\/j.drup.2025.101345_bib82","doi-asserted-by":"crossref","first-page":"7222","DOI":"10.1158\/0008-5472.CAN-13-1753","article-title":"APOBEC3B upregulation and genomic mutation patterns in serous ovarian carcinoma","volume":"73","author":"Leonard","year":"2013","journal-title":"Cancer Res"},{"key":"10.1016\/j.drup.2025.101345_bib83","doi-asserted-by":"crossref","first-page":"17320","DOI":"10.1021\/acsnano.3c05288","article-title":"Enantiomeric virus-inspired oncolytic particles for efficient antitumor immunotherapy","volume":"17","author":"Li","year":"2023","journal-title":"ACS Nano"},{"key":"10.1016\/j.drup.2025.101345_bib84","doi-asserted-by":"crossref","first-page":"1845","DOI":"10.1038\/s41467-022-29388-0","article-title":"Depletion of tumor associated macrophages enhances local and systemic platelet-mediated anti-PD-1 delivery for post-surgery tumor recurrence treatment","volume":"13","author":"Li","year":"2022","journal-title":"Nat. Commun."},{"key":"10.1016\/j.drup.2025.101345_bib85","doi-asserted-by":"crossref","first-page":"1129","DOI":"10.1016\/j.jconrel.2020.10.041","article-title":"Dendronized polymer conjugates with amplified immunogenic cell death for oncolytic immunotherapy","volume":"329","author":"Li","year":"2021","journal-title":"J. Control. Release"},{"key":"10.1016\/j.drup.2025.101345_bib86","article-title":"Mitochondria-targeted multifunctional nanoparticles combine cuproptosis and programmed cell death-1 downregulation for cancer immunotherapy","volume":"11","author":"Li","year":"2024","journal-title":"Adv. Sci. (Weinh. )"},{"key":"10.1016\/j.drup.2025.101345_bib87","doi-asserted-by":"crossref","first-page":"2216","DOI":"10.1038\/s41591-024-03025-3","article-title":"Oncolytic adenoviral therapy plus pembrolizumab in BCG-unresponsive non-muscle-invasive bladder cancer: the phase 2 CORE-001 trial","volume":"30","author":"Li","year":"2024","journal-title":"Nat. Med"},{"key":"10.1016\/j.drup.2025.101345_bib88","doi-asserted-by":"crossref","first-page":"2216","DOI":"10.1038\/s41591-024-03025-3","article-title":"Oncolytic adenoviral therapy plus pembrolizumab in BCG-unresponsive non-muscle-invasive bladder cancer: the phase 2 CORE-001 trial","volume":"30","author":"Li","year":"2024","journal-title":"Nat. Med"},{"key":"10.1016\/j.drup.2025.101345_bib89","doi-asserted-by":"crossref","first-page":"882","DOI":"10.1038\/s43018-020-0095-6","article-title":"Multifunctional oncolytic nanoparticles deliver self-replicating IL-12 RNA to eliminate established tumors and prime systemic immunity","volume":"1","author":"Li","year":"2020","journal-title":"Nat. Cancer"},{"key":"10.1016\/j.drup.2025.101345_bib90","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1016\/j.actbio.2024.02.044","article-title":"Tumor-targeted delivery of copper-manganese biomineralized oncolytic adenovirus for colorectal cancer immunotherapy","volume":"179","author":"Li","year":"2024","journal-title":"Acta Biomater."},{"key":"10.1016\/j.drup.2025.101345_bib91","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1038\/s41585-021-00483-z","article-title":"Using oncolytic viruses to ignite the tumour immune microenvironment in bladder cancer","volume":"18","author":"Li","year":"2021","journal-title":"Nat. Rev. Urol."},{"key":"10.1016\/j.drup.2025.101345_bib92","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1186\/s12943-022-01651-4","article-title":"The reversion of DNA methylation-induced miRNA silence via biomimetic nanoparticles-mediated gene delivery for efficient lung adenocarcinoma therapy","volume":"21","author":"Liang","year":"2022","journal-title":"Mol. Cancer"},{"key":"10.1016\/j.drup.2025.101345_bib93","doi-asserted-by":"crossref","first-page":"5452","DOI":"10.7150\/thno.87498","article-title":"Systemic delivery of glycosylated-PEG-masked oncolytic virus enhances targeting of antitumor immuno-virotherapy and modulates T and NK cell infiltration","volume":"13","author":"Liang","year":"2023","journal-title":"Theranostics"},{"key":"10.1016\/j.drup.2025.101345_bib94","doi-asserted-by":"crossref","DOI":"10.1126\/sciadv.abc3646","article-title":"Nanoparticle-enhanced chemo-immunotherapy to trigger robust antitumor immunity","volume":"6","author":"Liang","year":"2020","journal-title":"Sci. Adv."},{"key":"10.1016\/j.drup.2025.101345_bib95","doi-asserted-by":"crossref","DOI":"10.1002\/smll.202207535","article-title":"Esterase-activated, pH-responsive, and genetically targetable nano-prodrug for cancer cell photo-ablation","volume":"19","author":"Liang","year":"2023","journal-title":"Small"},{"key":"10.1016\/j.drup.2025.101345_bib96","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1016\/j.apsb.2023.08.012","article-title":"Cancer cell membrane-coated bacterial ghosts for highly efficient paclitaxel delivery against metastatic lung cancer","volume":"14","author":"Ling","year":"2024","journal-title":"Acta Pharm. Sin. B"},{"key":"10.1016\/j.drup.2025.101345_bib97","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1038\/s41586-023-06623-2","article-title":"Clinical trial links oncolytic immunoactivation to survival in glioblastoma","volume":"623","author":"Ling","year":"2023","journal-title":"Nature"},{"key":"10.1016\/j.drup.2025.101345_bib98","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1038\/s41586-023-06623-2","article-title":"Clinical trial links oncolytic immunoactivation to survival in glioblastoma","volume":"623","author":"Ling","year":"2023","journal-title":"Nature"},{"key":"10.1016\/j.drup.2025.101345_bib99","article-title":"Thymosin \u03b11 reverses oncolytic adenovirus-induced M2 polarization of macrophages to improve antitumor immunity and therapeutic efficacy","volume":"5","author":"Liu","year":"2024","journal-title":"Cell Rep. Med."},{"key":"10.1016\/j.drup.2025.101345_bib100","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1038\/s41392-024-02029-2","article-title":"Neoadjuvant oncolytic virus orienx010 and toripalimab in resectable acral melanoma: a phase Ib trial","volume":"9","author":"Liu","year":"2024","journal-title":"Signal Transduct. Target Ther."},{"key":"10.1016\/j.drup.2025.101345_bib101","article-title":"Erythrocyte-leveraged oncolytic virotherapy (ELeOVt): oncolytic virus assembly on erythrocyte surface to combat pulmonary metastasis and alleviate side effects","volume":"11","author":"Liu","year":"2024","journal-title":"Adv. Sci."},{"key":"10.1016\/j.drup.2025.101345_bib102","doi-asserted-by":"crossref","DOI":"10.1016\/j.smim.2025.101996","article-title":"Latest insights into oncolytic viro-immunotherapy with vesicular stomatitis virus","volume":"80","author":"Lizarralde-Guerrero","year":"2025","journal-title":"Semin. Immunol."},{"key":"10.1016\/j.drup.2025.101345_bib103","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1016\/j.ccell.2025.03.010","article-title":"The discrete charm of oncolytic viruses: toward the finish line","volume":"43","author":"Lowenstein","year":"2025","journal-title":"Cancer Cell"},{"key":"10.1016\/j.drup.2025.101345_bib104","doi-asserted-by":"crossref","first-page":"3456","DOI":"10.7150\/thno.71129","article-title":"Polymer chimera of stapled oncolytic peptide coupled with anti-PD-L1 peptide boosts immunotherapy of colorectal cancer","volume":"12","author":"Lu","year":"2022","journal-title":"Theranostics"},{"key":"10.1016\/j.drup.2025.101345_bib105","first-page":"1113","article-title":"A self-biomineralized novel adenovirus vectored COVID-19 vaccine for boosting immunization of mice","volume":"36","author":"Luo","year":"2021","journal-title":"zgbdx"},{"key":"10.1016\/j.drup.2025.101345_bib106","doi-asserted-by":"crossref","first-page":"966","DOI":"10.1038\/s41422-020-00395-4","article-title":"Manganese is critical for antitumor immune responses via cGAS-STING and improves the efficacy of clinical immunotherapy","volume":"30","author":"Lv","year":"2020","journal-title":"Cell Res."},{"key":"10.1016\/j.drup.2025.101345_bib107","doi-asserted-by":"crossref","first-page":"2993","DOI":"10.1021\/acs.nanolett.9b00145","article-title":"Genetically engineered cell membrane nanovesicles for oncolytic adenovirus delivery: a versatile platform for cancer virotherapy","volume":"19","author":"Lv","year":"2019","journal-title":"Nano Lett."},{"key":"10.1016\/j.drup.2025.101345_bib108","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41419-020-2236-3","article-title":"Characterization of virus-mediated immunogenic cancer cell death and the consequences for oncolytic virus-based immunotherapy of cancer","volume":"11","author":"Ma","year":"2020","journal-title":"Cell Death Dis."},{"key":"10.1016\/j.drup.2025.101345_bib109","article-title":"In situ mitochondrial biomineralization for drug-free cancer therapy","volume":"36","author":"Ma","year":"2024","journal-title":"Adv. Mater."},{"key":"10.1016\/j.drup.2025.101345_bib110","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1016\/j.jconrel.2021.02.035","article-title":"Oncolytic adenovirus with hyaluronidase activity that evades neutralizing antibodies: VCN-11","volume":"332","author":"Mato-Berciano","year":"2021","journal-title":"J. Control. Release"},{"key":"10.1016\/j.drup.2025.101345_bib111","doi-asserted-by":"crossref","first-page":"1721","DOI":"10.1038\/s41588-023-01504-w","article-title":"APOBEC3B regulates R-loops and promotes transcription-associated mutagenesis in cancer","volume":"55","author":"McCann","year":"2023","journal-title":"Nat. Genet"},{"key":"10.1016\/j.drup.2025.101345_bib112","doi-asserted-by":"crossref","first-page":"1808","DOI":"10.1016\/j.ymthe.2021.02.004","article-title":"Mesenchymal stromal cell delivery of oncolytic immunotherapy improves CAR-T cell antitumor activity","volume":"29","author":"McKenna","year":"2021","journal-title":"Mol. Ther."},{"key":"10.1016\/j.drup.2025.101345_bib113","doi-asserted-by":"crossref","DOI":"10.1016\/j.msec.2021.112258","article-title":"Smart co-delivery of miR-34a and cytotoxic peptides (LTX-315 and melittin) by chitosan based polyelectrolyte nanocarriers for specific cancer cell death induction","volume":"128","author":"Motiei","year":"2021","journal-title":"Mater. Sci. Eng. C"},{"key":"10.1016\/j.drup.2025.101345_bib114","doi-asserted-by":"crossref","DOI":"10.1016\/j.cej.2025.160853","article-title":"A fusion of oncolytic viruses and bispecific T-cell engagers for triple negative breast cancer immunotherapy","volume":"508","author":"Mu","year":"2025","journal-title":"Chem. Eng. J."},{"key":"10.1016\/j.drup.2025.101345_bib115","doi-asserted-by":"crossref","first-page":"3685","DOI":"10.1039\/D4TB02565B","article-title":"Decomposable STING nanoagonist-amplified oncolytic virotherapy through remodeling the immunosuppressive microenvironment of triple-negative breast cancer","volume":"13","author":"Mu","year":"2025","journal-title":"J. Mater. Chem. B"},{"key":"10.1016\/j.drup.2025.101345_bib116","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1016\/S1470-2045(24)00079-2","article-title":"LOAd703, an oncolytic virus-based immunostimulatory gene therapy, combined with chemotherapy for unresectable or metastatic pancreatic cancer (LOKON001): results from arm 1 of a non-randomised, single-centre, phase 1\/2 study","volume":"25","author":"Musher","year":"2024","journal-title":"Lancet Oncol."},{"key":"10.1016\/j.drup.2025.101345_bib117","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1016\/S1470-2045(24)00079-2","article-title":"LOAd703, an oncolytic virus-based immunostimulatory gene therapy, combined with chemotherapy for unresectable or metastatic pancreatic cancer (LOKON001): results from arm 1 of a non-randomised, single-centre, phase 1\/2 study","volume":"25","author":"Musher","year":"2024","journal-title":"Lancet Oncol."},{"key":"10.1016\/j.drup.2025.101345_bib118","doi-asserted-by":"crossref","first-page":"1370","DOI":"10.1038\/s41591-023-02347-y","article-title":"Oncolytic DNX-2401 virotherapy plus pembrolizumab in recurrent glioblastoma: a phase 1\/2 trial","volume":"29","author":"Nassiri","year":"2023","journal-title":"Nat. Med"},{"key":"10.1016\/j.drup.2025.101345_bib119","doi-asserted-by":"crossref","first-page":"1370","DOI":"10.1038\/s41591-023-02347-y","article-title":"Oncolytic DNX-2401 virotherapy plus pembrolizumab in recurrent glioblastoma: a phase 1\/2 trial","volume":"29","author":"Nassiri","year":"2023","journal-title":"Nat. Med"},{"key":"10.1016\/j.drup.2025.101345_bib120","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1016\/j.semcancer.2021.05.019","article-title":"Optimal timing of PD-1 blockade in combination with oncolytic virus therapy","volume":"86","author":"Nguyen","year":"2022","journal-title":"Semin Cancer Biol."},{"key":"10.1016\/j.drup.2025.101345_bib121","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1016\/j.ymthe.2024.01.006","article-title":"Genetically modified ZIKA virus as a microRNA-sensitive oncolytic virus against central nervous system tumors","volume":"32","author":"Novaes","year":"2024","journal-title":"Mol. Ther."},{"key":"10.1016\/j.drup.2025.101345_bib122","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.2302156120","article-title":"Microbially induced precipitation of silica by anaerobic methane-oxidizing consortia and implications for microbial fossil preservation","volume":"120","author":"Osorio-Rodriguez","year":"2023","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.drup.2025.101345_bib123","doi-asserted-by":"crossref","first-page":"3715","DOI":"10.1158\/1078-0432.CCR-23-3874","article-title":"Safety, efficacy, and biological data of T-cell\u2013enabling oncolytic adenovirus TILT-123 in advanced solid cancers from the TUNIMO monotherapy phase I trial","volume":"30","author":"Pakola","year":"2024","journal-title":"Clin. Cancer Res."},{"key":"10.1016\/j.drup.2025.101345_bib124","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1038\/s41423-021-00824-3","article-title":"Enhancing the HSV-1-mediated antitumor immune response by suppressing Bach1","volume":"19","author":"Pan","year":"2022","journal-title":"Cell Mol. Immunol."},{"key":"10.1016\/j.drup.2025.101345_bib125","doi-asserted-by":"crossref","DOI":"10.1002\/adma.202411886","article-title":"Polyamine-depleting hydrogen-bond organic frameworks unleash dendritic cell and T cell vigor for targeted CRISPR\/cas-assisted cancer immunotherapy","author":"Pan","year":"2025","journal-title":"Adv. Mater."},{"key":"10.1016\/j.drup.2025.101345_bib126","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/j.jconrel.2024.09.006","article-title":"Advancements of engineered live oncolytic biotherapeutics (microbe\/virus\/cells): preclinical research and clinical progress","volume":"375","author":"Qi","year":"2024","journal-title":"J. Control. Release"},{"key":"10.1016\/j.drup.2025.101345_bib127","doi-asserted-by":"crossref","DOI":"10.1002\/adma.202308241","article-title":"Self-destructive copper carriers induce pyroptosis and cuproptosis for efficient tumor immunotherapy against dormant and recurrent tumors","volume":"36","author":"Qiao","year":"2024","journal-title":"Adv. Mater."},{"key":"10.1016\/j.drup.2025.101345_bib128","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1016\/j.ccell.2020.12.022","article-title":"Oncolytic virotherapy-mediated anti-tumor response: a single-cell perspective","volume":"39","author":"Ramelyte","year":"2021","journal-title":"Cancer Cell"},{"key":"10.1016\/j.drup.2025.101345_bib129","doi-asserted-by":"crossref","first-page":"4909","DOI":"10.1038\/s41467-020-18626-y","article-title":"Hybrid cellular membrane nanovesicles amplify macrophage immune responses against cancer recurrence and metastasis","volume":"11","author":"Rao","year":"2020","journal-title":"Nat. Commun."},{"key":"10.1016\/j.drup.2025.101345_bib130","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1038\/s43018-024-00879-x","article-title":"Efficacy and tolerability of neoadjuvant therapy with Talimogene laherparepvec in cutaneous basal cell carcinoma: a phase II trial (NeoBCC trial)","volume":"6","author":"Ressler","year":"2025","journal-title":"Nat. Cancer"},{"key":"10.1016\/j.drup.2025.101345_bib131","doi-asserted-by":"crossref","first-page":"1109","DOI":"10.1016\/j.cell.2017.08.027","article-title":"Oncolytic virotherapy promotes intratumoral T cell infiltration and improves anti-PD-1 immunotherapy","volume":"170","author":"Ribas","year":"2017","journal-title":"Cell"},{"key":"10.1016\/j.drup.2025.101345_bib132","doi-asserted-by":"crossref","first-page":"1658","DOI":"10.1158\/1078-0432.CCR-22-2861","article-title":"Clinical implications of APOBEC3-mediated mutagenesis in breast cancer","volume":"29","author":"Roelofs","year":"2023","journal-title":"Clin. Cancer Res"},{"key":"10.1016\/j.drup.2025.101345_bib133","doi-asserted-by":"crossref","DOI":"10.1136\/jitc-2022-005007","article-title":"Phase 1, open-label, dose-escalation study on the safety, pharmacokinetics, and preliminary efficacy of intravenous Coxsackievirus A21 (V937), with or without pembrolizumab, in patients with advanced solid tumors","volume":"11","author":"Rudin","year":"2023","journal-title":"J. Immunother. Cancer"},{"key":"10.1016\/j.drup.2025.101345_bib134","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/j.jconrel.2019.01.034","article-title":"Silica cloaking of adenovirus enhances gene delivery while reducing immunogenicity","volume":"297","author":"Sapre","year":"2019","journal-title":"J. Control. Release"},{"key":"10.1016\/j.drup.2025.101345_bib135","doi-asserted-by":"crossref","DOI":"10.1016\/j.cis.2025.103457","article-title":"Lipid-based nanocarriers loaded with bioactive compounds in active food packaging: fabrication, characterization, and applications","volume":"340","author":"Seyyedi-Mansour","year":"2025","journal-title":"Adv. Colloid Interface Sci."},{"key":"10.1016\/j.drup.2025.101345_bib136","doi-asserted-by":"crossref","first-page":"7283","DOI":"10.1021\/jacs.2c00452","article-title":"Heterochiral \u03b2-peptide polymers combating multidrug-resistant cancers effectively without inducing drug resistance","volume":"144","author":"Shao","year":"2022","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.drup.2025.101345_bib137","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1038\/s41586-025-08717-5","article-title":"Oncolytic virus VG161 in refractory hepatocellular carcinoma","volume":"641","author":"Shen","year":"2025","journal-title":"Nature"},{"key":"10.1016\/j.drup.2025.101345_bib138","doi-asserted-by":"crossref","first-page":"25638","DOI":"10.1021\/acsnano.3c10302","article-title":"Systemic administration with bacteria-inspired nanosystems for targeted oncolytic therapy and antitumor immunomodulation","volume":"17","author":"Shen","year":"2023","journal-title":"ACS Nano"},{"key":"10.1016\/j.drup.2025.101345_bib139","doi-asserted-by":"crossref","first-page":"e581","DOI":"10.1016\/S2666-5247(23)00410-X","article-title":"SARS-CoV-2 recombinant spike ferritin nanoparticle vaccine adjuvanted with army liposome formulation containing monophosphoryl lipid a and QS-21: a phase 1, randomised, double-blind, placebo-controlled, first-in-human clinical trial","volume":"5","author":"Shepherd","year":"2024","journal-title":"Lancet Microbe"},{"key":"10.1016\/j.drup.2025.101345_bib140","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1038\/s41467-023-44226-7","article-title":"Silica-associated proteins from hexactinellid sponges support an alternative evolutionary scenario for biomineralization in porifera","volume":"15","author":"Shimizu","year":"2024","journal-title":"Nat. Commun."},{"key":"10.1016\/j.drup.2025.101345_bib141","doi-asserted-by":"crossref","first-page":"722","DOI":"10.1016\/j.ymthe.2024.01.035","article-title":"Chimeric oncolytic adenovirus evades neutralizing antibodies from human patients and exhibits enhanced anti-glioma efficacy in immunized mice","volume":"32","author":"Shin","year":"2024","journal-title":"Mol. Ther."},{"key":"10.1016\/j.drup.2025.101345_bib142","first-page":"447","article-title":"Metal alginates for polyphenol delivery systems: studies on crosslinking ions and easy-to-use patches for release of protective flavonoids in skin","volume":"5","author":"Silva","year":"2020","journal-title":"Bioact. Mater."},{"key":"10.1016\/j.drup.2025.101345_bib143","doi-asserted-by":"crossref","first-page":"554","DOI":"10.1038\/s41565-023-01577-y","article-title":"Urease-powered nanobots for radionuclide bladder cancer therapy","volume":"19","author":"Sim\u00f3","year":"2024","journal-title":"Nat. Nanotechnol."},{"key":"10.1016\/j.drup.2025.101345_bib144","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1038\/s41591-023-02309-4","article-title":"Oncolytic T-VEC virotherapy plus neoadjuvant chemotherapy in nonmetastatic triple-negative breast cancer: A phase 2 trial","volume":"29","author":"Soliman","year":"2023","journal-title":"Nat. Med"},{"key":"10.1016\/j.drup.2025.101345_bib145","doi-asserted-by":"crossref","DOI":"10.1186\/s40425-019-0505-4","article-title":"Targeting the tumor stroma with an oncolytic adenovirus secreting a fibroblast activation protein-targeted bispecific T-cell engager","volume":"7","author":"Sostoa","year":"2019","journal-title":"J. Immunother. Cancer"},{"key":"10.1016\/j.drup.2025.101345_bib146","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.canlet.2020.12.018","article-title":"Combining NanoKnife with M1 oncolytic virus enhances anticancer activity in pancreatic cancer","volume":"502","author":"Sun","year":"2021","journal-title":"Cancer Lett."},{"key":"10.1016\/j.drup.2025.101345_bib147","doi-asserted-by":"crossref","first-page":"30332","DOI":"10.1021\/acsnano.4c07364","article-title":"Engineered outer membrane vesicles as nanosized immune cell engagers for enhanced solid tumor immunotherapy","volume":"18","author":"Sun","year":"2024","journal-title":"ACS Nano"},{"key":"10.1016\/j.drup.2025.101345_bib148","doi-asserted-by":"crossref","DOI":"10.1016\/j.addr.2022.114614","article-title":"The tumor EPR effect for cancer drug delivery: current status, limitations, and alternatives","volume":"191","author":"Sun","year":"2022","journal-title":"Adv. Drug Deliv. Rev."},{"key":"10.1016\/j.drup.2025.101345_bib149","doi-asserted-by":"crossref","first-page":"1260","DOI":"10.1038\/s41565-021-00962-9","article-title":"Amplifying STING activation by cyclic dinucleotide\u2013manganese particles for local and systemic cancer metalloimmunotherapy","volume":"16","author":"Sun","year":"2021","journal-title":"Nat. Nanotechnol."},{"key":"10.1016\/j.drup.2025.101345_bib150","doi-asserted-by":"crossref","DOI":"10.1016\/j.redox.2024.103144","article-title":"S-nitrosocysteamine-functionalised porous graphene oxide nanosheets as nitric oxide delivery vehicles for cardiovascular applications","volume":"72","author":"Tabish","year":"2024","journal-title":"Redox Biol."},{"key":"10.1016\/j.drup.2025.101345_bib151","doi-asserted-by":"crossref","DOI":"10.1136\/jitc-2021-004129","article-title":"Oncolytic peptide LTX-315 induces anti-pancreatic cancer immunity by targeting the ATP11B-PD-L1 axis","volume":"10","author":"Tang","year":"2022","journal-title":"J. Immunother. Cancer"},{"key":"10.1016\/j.drup.2025.101345_bib152","doi-asserted-by":"crossref","DOI":"10.1002\/adma.202415643","article-title":"Modular design of lipopeptide-based organ-specific targeting (POST) lipid nanoparticles for highly efficient RNA delivery","author":"Tang","year":"2025","journal-title":"Adv. Mater."},{"key":"10.1016\/j.drup.2025.101345_bib153","doi-asserted-by":"crossref","first-page":"1067","DOI":"10.1038\/s41565-023-01455-7","article-title":"Cholesterol modulates the physiological response to nanoparticles by changing the composition of protein corona","volume":"18","author":"Tang","year":"2023","journal-title":"Nat. Nanotechnol."},{"key":"10.1016\/j.drup.2025.101345_bib154","doi-asserted-by":"crossref","DOI":"10.1002\/adma.202408361","article-title":"Dismountable protein corona-modified virus-like manganese-arsenic nanomedicine enables safe and targeted delivery for synergistic arsenotherapy","volume":"36","author":"Tian","year":"2024","journal-title":"Adv. Mater."},{"key":"10.1016\/j.drup.2025.101345_bib155","doi-asserted-by":"crossref","first-page":"1630","DOI":"10.1038\/s41591-022-01897-x","article-title":"Intratumoral oncolytic herpes virus G47\u2206 for residual or recurrent glioblastoma: a phase 2 trial","volume":"28","author":"Todo","year":"2022","journal-title":"Nat. Med"},{"key":"10.1016\/j.drup.2025.101345_bib156","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1186\/s13045-022-01370-9","article-title":"Randomized phase 2 trial of intravenous oncolytic virus JX-594 combined with low-dose cyclophosphamide in patients with advanced soft-tissue sarcoma","volume":"15","author":"Toulmonde","year":"2022","journal-title":"J. Hematol. Oncol."},{"key":"10.1016\/j.drup.2025.101345_bib157","doi-asserted-by":"crossref","first-page":"9894","DOI":"10.1021\/acsnano.8b02813","article-title":"Targeting tumor microenvironment by bioreduction-activated nanoparticles for light-triggered virotherapy","volume":"12","author":"Tseng","year":"2018","journal-title":"ACS Nano"},{"key":"10.1016\/j.drup.2025.101345_bib158","doi-asserted-by":"crossref","DOI":"10.1016\/j.nantod.2022.101582","article-title":"An acid degradable, lactate oxidizing nanoparticle formulation for non-small cell lung cancer virotherapy","volume":"46","author":"Tseng","year":"2022","journal-title":"Nano Today"},{"key":"10.1016\/j.drup.2025.101345_bib159","article-title":"Harnessing nanoengineered CAR-T cell strategies to advance solid tumor immunotherapy","author":"Wang","year":"2024","journal-title":"Trends Cell Biol."},{"key":"10.1016\/j.drup.2025.101345_bib160","article-title":"Bimetallic nanodot-adenovirus chimera for cancer theranostics via cooperativity of autophagy and ferroptosis","volume":"5","author":"Wang","year":"2024","journal-title":"CRPHYSSC"},{"key":"10.1016\/j.drup.2025.101345_bib161","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1021\/acs.molpharmaceut.8b01046","article-title":"Liposome encapsulation of oncolytic virus M1 To reduce immunogenicity and immune clearance in vivo","volume":"16","author":"Wang","year":"2019","journal-title":"Mol. Pharm."},{"key":"10.1016\/j.drup.2025.101345_bib162","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1186\/s13046-025-03358-y","article-title":"Viral expression of NE\/PPE enhances anti-colorectal cancer efficacy of oncolytic adenovirus by promoting TAM M1 polarization to reverse insufficient effector memory\/effector CD8+ T cell infiltration","volume":"44","author":"Wang","year":"2025","journal-title":"J. Exp. Clin. Cancer Res"},{"key":"10.1016\/j.drup.2025.101345_bib163","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1080\/15583724.2024.2401992","article-title":"Recent development and advances on polysaccharide composite scaffolds for dental and dentoalveolar tissue regeneration","volume":"65","author":"Wang","year":"2025","journal-title":"Polym. Rev."},{"key":"10.1016\/j.drup.2025.101345_bib164","first-page":"1","article-title":"Systemic delivery of tannic acid-ferric-masked oncolytic adenovirus reprograms tumor microenvironment for improved therapeutic efficacy in glioblastoma","author":"Wang","year":"2024","journal-title":"Cancer Gene Ther."},{"key":"10.1016\/j.drup.2025.101345_bib165","article-title":"Dual-gradient silk-based hydrogel for spatially targeted delivery and osteochondral regeneration","author":"Wang","year":"2025","journal-title":"Adv. Mater."},{"key":"10.1016\/j.drup.2025.101345_bib166","doi-asserted-by":"crossref","first-page":"20167","DOI":"10.1021\/acsnano.4c03034","article-title":"Dual-responsive epigenetic inhibitor nanoprodrug combined with oncolytic virus synergistically boost cancer immunotherapy by igniting gasdermin E-mediated pyroptosis","volume":"18","author":"Wang","year":"2024","journal-title":"ACS Nano"},{"key":"10.1016\/j.drup.2025.101345_bib167","article-title":"A metal\u2013polyphenol-based antidepressant for alleviating colitis-associated mental disorders","volume":"37","author":"Wang","year":"2025","journal-title":"Adv. Mater."},{"key":"10.1016\/j.drup.2025.101345_bib168","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1021\/nn5063276","article-title":"Hydrated silica exterior produced by biomimetic silicification confers viral vaccine heat-resistance","volume":"9","author":"Wang","year":"2015","journal-title":"ACS Nano"},{"key":"10.1016\/j.drup.2025.101345_bib169","article-title":"Transcytosable and ultrasound-activated liposome enables deep penetration of biofilm for surgical site infection management","volume":"37","author":"Wang","year":"2025","journal-title":"Adv. Mater."},{"key":"10.1016\/j.drup.2025.101345_bib170","doi-asserted-by":"crossref","DOI":"10.1002\/anie.202210487","article-title":"An ion-enhanced oncolytic virus-like nanoparticle for tumor immunotherapy","volume":"61","author":"Wu","year":"2022","journal-title":"Angew. Chem. Int. Ed."},{"key":"10.1016\/j.drup.2025.101345_bib171","article-title":"Oncolytic peptide-nanoplatform drives oncoimmune response and reverses adenosine-induced immunosuppressive tumor microenvironment","volume":"13","author":"Wu","year":"2024","journal-title":"Adv. Healthc. Mater."},{"key":"10.1016\/j.drup.2025.101345_bib172","doi-asserted-by":"crossref","DOI":"10.1002\/adma.202005181","article-title":"Bioinspired artificial tobacco mosaic virus with combined oncolytic properties to completely destroy multidrug-resistant cancer","volume":"32","author":"Wu","year":"2020","journal-title":"Adv. Mater."},{"key":"10.1016\/j.drup.2025.101345_bib173","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1186\/s13046-019-1410-x","article-title":"Graphene oxide arms oncolytic measles virus for improved effectiveness of cancer therapy","volume":"38","author":"Xia","year":"2019","journal-title":"J. Exp. Clin. Cancer Res"},{"key":"10.1016\/j.drup.2025.101345_bib174","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1016\/j.jconrel.2021.06.032","article-title":"Systemic administration of polymersomal oncolytic peptide LTX-315 combining with CpG adjuvant and anti-PD-1 antibody boosts immunotherapy of melanoma","volume":"336","author":"Xia","year":"2021","journal-title":"J. Control. Release"},{"key":"10.1016\/j.drup.2025.101345_bib175","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijbiomac.2023.127919","article-title":"Preparation and optimization of agarose or polyacrylamide\/amino acid-based double network hydrogels for photocontrolled drug release","volume":"255","author":"Xiang","year":"2024","journal-title":"Int J. Biol. Macromol."},{"key":"10.1016\/j.drup.2025.101345_bib176","doi-asserted-by":"crossref","first-page":"21091","DOI":"10.1021\/acsnano.4c02560","article-title":"Milk exosome-liposome hybrid vesicles with self-adapting surface properties overcome the sequential absorption barriers for oral delivery of peptides","volume":"18","author":"Xiao","year":"2024","journal-title":"ACS Nano"},{"key":"10.1016\/j.drup.2025.101345_bib177","article-title":"Oncolytic adenovirus-loaded magnetic-driven Janus tumor cell robots for active and targeted virotherapy of homologous carcinoma","volume":"30","author":"Xie","year":"2023","journal-title":"Mater. Today Chem."},{"key":"10.1016\/j.drup.2025.101345_bib178","doi-asserted-by":"crossref","first-page":"19756","DOI":"10.1021\/acsnano.1c07180","article-title":"Cancer-erythrocyte hybrid membrane-camouflaged magnetic nanoparticles with enhanced photothermal-immunotherapy for ovarian cancer","volume":"15","author":"Xiong","year":"2021","journal-title":"ACS Nano"},{"key":"10.1016\/j.drup.2025.101345_bib179","doi-asserted-by":"crossref","DOI":"10.1016\/j.nantod.2023.101922","article-title":"Antigen-capturing oncolytic adenoviruses along with IDO blockade for improved tumor immunotherapy","volume":"51","author":"Xu","year":"2023","journal-title":"Nano Today"},{"key":"10.1016\/j.drup.2025.101345_bib180","article-title":"Platelet membrane nanocarriers cascade targeting delivery system to improve myocardial remodeling post myocardial ischemia-reperfusion injury","volume":"11","author":"Xu","year":"2024","journal-title":"Adv. Sci. (Weinh. )"},{"key":"10.1016\/j.drup.2025.101345_bib181","article-title":"Molecular engineering of a tumor-targeting thione-derived diketopyrrolopyrrole photosensitizer to attain NIR excitation over 850 nm for efficient dual phototherapy","volume":"11","author":"Xu","year":"2024","journal-title":"Adv. Sci. (Weinh. )"},{"key":"10.1016\/j.drup.2025.101345_bib182","doi-asserted-by":"crossref","DOI":"10.1038\/s41565-025-01860-0","article-title":"A bioinspired polymeric membrane-enclosed insulin crystal achieves long-term, self-regulated drug release for type 1 diabetes therapy","author":"Xu","year":"2025","journal-title":"Nat. Nanotechnol."},{"key":"10.1016\/j.drup.2025.101345_bib183","doi-asserted-by":"crossref","first-page":"6502","DOI":"10.1038\/s41467-024-50859-z","article-title":"The coupling of rotational and translational dynamics for rapid diffusion of nanorods in macromolecular networks","volume":"15","author":"Xue","year":"2024","journal-title":"Nat. Commun."},{"key":"10.1016\/j.drup.2025.101345_bib184","doi-asserted-by":"crossref","DOI":"10.1016\/j.carbpol.2024.122743","article-title":"Tunable supramolecular self-assemblies based on cyclodextrin polymer as a loading platform for water-soluble drugs","volume":"347","author":"Yang","year":"2025","journal-title":"Carbohydr. Polym."},{"key":"10.1016\/j.drup.2025.101345_bib185","article-title":"Construction of liposome-based extracellular artificial organelles on individual living cells","volume":"64","author":"Yang","year":"2025","journal-title":"Angew. Chem. Int Ed. Engl."},{"key":"10.1016\/j.drup.2025.101345_bib186","doi-asserted-by":"crossref","DOI":"10.1016\/j.biomaterials.2022.121488","article-title":"Oncolytic peptide nanomachine circumvents chemo resistance of renal cell carcinoma","volume":"284","author":"Yang","year":"2022","journal-title":"Biomaterials"},{"key":"10.1016\/j.drup.2025.101345_bib187","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1016\/j.actbio.2024.04.044","article-title":"Enzyme-responsive oncolytic polypeptide for tumor therapy","volume":"181","author":"Yin","year":"2024","journal-title":"Acta Biomater."},{"key":"10.1016\/j.drup.2025.101345_bib188","article-title":"Engineered bacterial outer membrane vesicles-based doxorubicin and CD47-siRNA co-delivery nanoplatform overcomes immune resistance to potentiate the immunotherapy of glioblastoma","author":"You","year":"2025","journal-title":"Adv. Mater."},{"key":"10.1016\/j.drup.2025.101345_bib189","article-title":"Engineering antimicrobial metal\u2013phenolic network nanoparticles with high biocompatibility for wound healing","volume":"36","author":"Yu","year":"2024","journal-title":"Adv. Mater."},{"key":"10.1016\/j.drup.2025.101345_bib190","doi-asserted-by":"crossref","DOI":"10.1126\/sciadv.add3599","article-title":"Engineered drug-loaded cellular membrane nanovesicles for efficient treatment of postsurgical cancer recurrence and metastasis","volume":"8","author":"Yu","year":"2022","journal-title":"Sci. Adv."},{"key":"10.1016\/j.drup.2025.101345_bib191","doi-asserted-by":"crossref","first-page":"1369","DOI":"10.1093\/annonc\/mdm178","article-title":"VAD-doxil versus VAD-doxil plus thalidomide as initial treatment for multiple myeloma: Results of a multicenter randomized trial of the greek myeloma study group","volume":"18","author":"Zervas","year":"2007","journal-title":"Ann. Oncol."},{"key":"10.1016\/j.drup.2025.101345_bib192","article-title":"Mitochondrial-targeted delivery of polyphenol-mediated antioxidases complexes against pyroptosis and inflammatory diseases","volume":"35","author":"Zhang","year":"2023","journal-title":"Adv. Mater."},{"key":"10.1016\/j.drup.2025.101345_bib193","article-title":"Copper-bacteriochlorin nanosheet as a specific pyroptosis inducer for robust tumor immunotherapy","volume":"35","author":"Zhang","year":"2023","journal-title":"Adv. Mater."},{"key":"10.1016\/j.drup.2025.101345_bib194","doi-asserted-by":"crossref","DOI":"10.1002\/advs.202303818","article-title":"Multi-bioinspired MOF delivery systems from microfluidics for tumor multimodal therapy","volume":"10","author":"Zhang","year":"2023","journal-title":"Adv. Sci."},{"key":"10.1016\/j.drup.2025.101345_bib195","doi-asserted-by":"crossref","first-page":"18483","DOI":"10.1021\/acsnano.2c06666","article-title":"Platelet-covered nanocarriers for targeted delivery of hirudin to eliminate thrombotic complication in tumor therapy","volume":"16","author":"Zhang","year":"2022","journal-title":"ACS Nano"},{"key":"10.1016\/j.drup.2025.101345_bib196","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1002\/cac2.12225","volume":"42","author":"Zhang","year":"2022","journal-title":"Cancer Commun."},{"key":"10.1016\/j.drup.2025.101345_bib197","article-title":"Fast and dynamic mapping of the protein corona on nanoparticle surfaces by photocatalytic proximity labeling","volume":"35","author":"Zhang","year":"2023","journal-title":"Adv. Mater."},{"key":"10.1016\/j.drup.2025.101345_bib198","article-title":"Virion-like membrane-breaking nanoparticles with tumor-activated cell-and-tissue dual-penetration conquer impermeable cancer","volume":"30","author":"Zhang","year":"2018","journal-title":"Adv. Mater."},{"key":"10.1016\/j.drup.2025.101345_bib199","doi-asserted-by":"crossref","first-page":"1906","DOI":"10.1016\/j.ymthe.2019.07.019","article-title":"Recombinant adenovirus expressing a soluble fusion protein PD-1\/CD137L subverts the suppression of CD8+ T cells in HCC","volume":"27","author":"Zhang","year":"2019","journal-title":"Mol. Ther."},{"key":"10.1016\/j.drup.2025.101345_bib200","article-title":"Pistol ribozyme-driven catalytic spherical nucleic acid integrates gene and chemotherapy for enhanced cancer therapy","author":"Zhang","year":"2025","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.drup.2025.101345_bib201","doi-asserted-by":"crossref","first-page":"27869","DOI":"10.1021\/acsnano.4c02165","article-title":"Smart accumulating dual-targeting lipid envelopes equipping oncolytic adenovirus for enhancing cancer gene therapeutic efficacy","volume":"18","author":"Zhao","year":"2024","journal-title":"ACS Nano"},{"key":"10.1016\/j.drup.2025.101345_bib202","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1016\/j.ymthe.2024.12.017","article-title":"Single-cell data-driven design of armed oncolytic virus to boost cooperative innate-adaptive immunity against cancer","volume":"33","author":"Zhao","year":"2025","journal-title":"Mol. Ther."},{"key":"10.1016\/j.drup.2025.101345_bib203","article-title":"Dual-protection inorganic-protein coating on mg-based biomaterials through tooth-enamel-inspired biomineralization","volume":"36","author":"Zhao","year":"2024","journal-title":"Adv. Mater."},{"key":"10.1016\/j.drup.2025.101345_bib204","doi-asserted-by":"crossref","DOI":"10.1002\/advs.202102741","article-title":"Self-stabilized supramolecular assemblies constructed from PEGylated dendritic peptide conjugate for augmenting tumor retention and therapy","volume":"8","author":"Zheng","year":"2021","journal-title":"Adv. Sci."},{"key":"10.1016\/j.drup.2025.101345_bib205","doi-asserted-by":"crossref","first-page":"1119","DOI":"10.1016\/j.cell.2024.12.010","article-title":"Hyperacute rejection-engineered oncolytic virus for interventional clinical trial in refractory cancer patients","volume":"188","author":"Zhong","year":"2025","journal-title":"Cell"},{"key":"10.1016\/j.drup.2025.101345_bib206","article-title":"Emerging delivery strategy for oncolytic virotherapy","volume":"32","author":"Zhu","year":"2024","journal-title":"Mol. Ther. Oncol."},{"key":"10.1016\/j.drup.2025.101345_bib207","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1186\/s12943-022-01664-z","article-title":"Improving cancer immunotherapy by rationally combining oncolytic virus with modulators targeting key signaling pathways","volume":"21","author":"Zhu","year":"2022","journal-title":"Mol. Cancer"},{"key":"10.1016\/j.drup.2025.101345_bib208","doi-asserted-by":"crossref","first-page":"1858","DOI":"10.1038\/s41565-024-01785-0","article-title":"Direct cytosolic delivery of siRNA via cell membrane fusion using cholesterol-enriched exosomes","volume":"19","author":"Zhuo","year":"2024","journal-title":"Nat. Nanotechnol."}],"container-title":["Drug Resistance Updates"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1368764625001487?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1368764625001487?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,3,20]],"date-time":"2026-03-20T02:37:28Z","timestamp":1773974248000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1368764625001487"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3]]},"references-count":208,"alternative-id":["S1368764625001487"],"URL":"https:\/\/doi.org\/10.1016\/j.drup.2025.101345","relation":{},"ISSN":["1368-7646"],"issn-type":[{"value":"1368-7646","type":"print"}],"subject":[],"published":{"date-parts":[[2026,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Overcoming resistance in oncolytic virotherapy: Nano-engineered solutions for systemic delivery and efficacy boost","name":"articletitle","label":"Article Title"},{"value":"Drug Resistance Updates","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.drup.2025.101345","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"101345"}}