{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T13:55:09Z","timestamp":1784901309646,"version":"3.55.0"},"reference-count":157,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2015,1,1]],"date-time":"2015-01-01T00:00:00Z","timestamp":1420070400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Diabetes &amp; Metabolic Syndrome: Clinical Research &amp; Reviews"],"published-print":{"date-parts":[[2015,1]]},"DOI":"10.1016\/j.dsx.2014.05.001","type":"journal-article","created":{"date-parts":[[2014,6,3]],"date-time":"2014-06-03T02:30:49Z","timestamp":1401762649000},"page":"55-64","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":72,"title":["Protective and therapeutic effectiveness of taurine in diabetes mellitus: A rationale for antioxidant supplementation"],"prefix":"10.1016","volume":"9","author":[{"given":"Mahmoud M.","family":"Sirdah","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"2","key":"10.1016\/j.dsx.2014.05.001_bib0005","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1002\/andp.18270850214","article-title":"Einige neue Bestandtheile der Galle des Ochsen","volume":"85","author":"Tiedemann","year":"1827","journal-title":"Ann Phys"},{"issue":"3","key":"10.1016\/j.dsx.2014.05.001_bib0010","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1002\/jlac.18380270304","article-title":"Uber die Natur der Galle","volume":"27","author":"Demarcay","year":"1838","journal-title":"Ann Pharm"},{"key":"10.1016\/j.dsx.2014.05.001_bib0015","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1152\/physrev.1992.72.1.101","article-title":"Physiological actions of taurine","volume":"72","author":"Huxtable","year":"1992","journal-title":"Physiol Rev"},{"key":"10.1016\/j.dsx.2014.05.001_bib0020","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1007\/978-1-4899-0182-8_71","article-title":"Taurine. Past, present, and future","volume":"403","author":"Huxtable","year":"1996","journal-title":"Adv Exp Med Biol"},{"key":"10.1016\/j.dsx.2014.05.001_bib0025","first-page":"8","article-title":"Pharmacology of taurine","volume":"50","author":"Oja","year":"2007","journal-title":"Proc West Pharmacol Soc"},{"key":"10.1016\/j.dsx.2014.05.001_bib0030","first-page":"57","article-title":"The potential health benefits of taurine in cardiovascular disease","volume":"13","author":"Xu","year":"2008","journal-title":"Exp Clin Cardiol"},{"issue":"Suppl. 1","key":"10.1016\/j.dsx.2014.05.001_bib0035","doi-asserted-by":"crossref","first-page":"S2","DOI":"10.1186\/1423-0127-17-S1-S2","article-title":"Physiological roles of taurine in heart and muscle","volume":"17","author":"Schaffer","year":"2010","journal-title":"J Biomed Sci"},{"issue":"Suppl. 1","key":"10.1016\/j.dsx.2014.05.001_bib0040","doi-asserted-by":"crossref","first-page":"S1","DOI":"10.1186\/1423-0127-17-S1-S1","article-title":"Role of taurine in the central nervous system","volume":"17","author":"Wu","year":"2010","journal-title":"J Biomed Sci"},{"issue":"Suppl. 1","key":"10.1016\/j.dsx.2014.05.001_bib0045","doi-asserted-by":"crossref","first-page":"S6","DOI":"10.1186\/1423-0127-17-S1-S6","article-title":"Taurine in health and diseases: consistent evidence from experimental and epidemiological studies","volume":"17","author":"Yamori","year":"2010","journal-title":"J Biomed Sci"},{"key":"10.1016\/j.dsx.2014.05.001_bib0050","first-page":"293","article-title":"Role of taurine in the vasculature: an overview of experimental and human studies","volume":"1","author":"Abebe","year":"2011","journal-title":"Am J Cardiovasc Dis"},{"key":"10.1016\/j.dsx.2014.05.001_bib0055","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1097\/MCO.0b013e328340d863","article-title":"Taurine in cardiovascular disease","volume":"14","author":"Zulli","year":"2011","journal-title":"Curr Opin Clin Nutr Metab Care"},{"key":"10.1016\/j.dsx.2014.05.001_bib0060","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1007\/s00726-012-1382-z","article-title":"Taurine and central nervous system disorders","volume":"46","author":"Menzie","year":"2014","journal-title":"Amino Acids"},{"key":"10.1016\/j.dsx.2014.05.001_bib0065","first-page":"2673","article-title":"Review: taurine: a \u201cvery essential\u201d amino acid","volume":"18","author":"Ripps","year":"2012","journal-title":"Mol Vis"},{"key":"10.1016\/j.dsx.2014.05.001_bib0070","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1002\/(SICI)1096-9136(199807)15:7<539::AID-DIA668>3.0.CO;2-S","article-title":"Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: Diagnosis and classification of diabetes mellitus provisional report of a WHO consultation","volume":"15","author":"Alberti","year":"1998","journal-title":"Diabet Med"},{"issue":"Suppl. 2","key":"10.1016\/j.dsx.2014.05.001_bib0075","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s00508-012-0269-z","article-title":"Diabetes mellitus: definition, classification and diagnosis","volume":"124","author":"Roden","year":"2012","journal-title":"Wien Klin Wochenschr"},{"issue":"Suppl. 1","key":"10.1016\/j.dsx.2014.05.001_bib0080","doi-asserted-by":"crossref","first-page":"S67","DOI":"10.2337\/dc13-S067","article-title":"Diagnosis and classification of diabetes mellitus","volume":"36","author":"American Diabetes","year":"2013","journal-title":"Diabetes Care"},{"key":"10.1016\/j.dsx.2014.05.001_bib0085","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1002\/jbt.10058","article-title":"Diabetes, oxidative stress, and antioxidants: a review","volume":"17","author":"Maritim","year":"2003","journal-title":"J Biochem Mol Toxicol"},{"key":"10.1016\/j.dsx.2014.05.001_bib0090","doi-asserted-by":"crossref","first-page":"1115","DOI":"10.1093\/ajcn\/61.5.1115","article-title":"Plasma and platelet taurine are reduced in subjects with insulin-dependent diabetes mellitus: effects of taurine supplementation","volume":"61","author":"Franconi","year":"1995","journal-title":"Am J Clin Nutr"},{"key":"10.1016\/j.dsx.2014.05.001_bib0095","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1007\/978-1-4899-0182-8_62","article-title":"Taurine and diabetes. Humans and experimental models","volume":"403","author":"Franconi","year":"1996","journal-title":"Adv Exp Med Biol"},{"key":"10.1016\/j.dsx.2014.05.001_bib0100","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1023\/B:NERE.0000010443.05899.2f","article-title":"Is taurine beneficial in reducing risk factors for diabetes mellitus?","volume":"29","author":"Franconi","year":"2004","journal-title":"Neurochem Res"},{"key":"10.1016\/j.dsx.2014.05.001_bib0105","doi-asserted-by":"crossref","first-page":"1322","DOI":"10.2522\/ptj.20080008","article-title":"Diabetes-related microvascular and macrovascular diseases in the physical therapy setting","volume":"88","author":"Cade","year":"2008","journal-title":"Phys Ther"},{"issue":"2","key":"10.1016\/j.dsx.2014.05.001_bib0110","doi-asserted-by":"crossref","first-page":"77","DOI":"10.2337\/diaclin.26.2.77","article-title":"Microvascular and macrovascular complications of diabetes","volume":"26","author":"Fowler","year":"2008","journal-title":"Clin Diabetes"},{"key":"10.1016\/j.dsx.2014.05.001_bib0115","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1111\/j.1365-2605.2008.00873.x","article-title":"Assessment of erectile dysfunction in diabetic patients","volume":"32","author":"Hamdan","year":"2009","journal-title":"Int J Androl"},{"key":"10.1016\/j.dsx.2014.05.001_bib0120","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1186\/1477-7827-9-70","article-title":"Determinants of sexual dysfunction among clinically diagnosed diabetic patients","volume":"9","author":"Owiredu","year":"2011","journal-title":"Reprod Biol Endocrinol"},{"key":"10.1016\/j.dsx.2014.05.001_bib0125","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1111\/j.1447-0594.2012.00928.x","article-title":"Quality of life in elderly diabetic patients with peripheral arterial disease","volume":"13","author":"Amer","year":"2013","journal-title":"Geriatr Gerontol Int"},{"key":"10.1016\/j.dsx.2014.05.001_bib0130","doi-asserted-by":"crossref","first-page":"1047","DOI":"10.2337\/diacare.27.5.1047","article-title":"Global prevalence of diabetes: estimates for the year 2000 and projections for 2030","volume":"27","author":"Wild","year":"2004","journal-title":"Diabetes Care"},{"key":"10.1016\/j.dsx.2014.05.001_bib0135","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/j.diabres.2010.01.026","article-title":"Global healthcare expenditure on diabetes for 2010 and 2030","volume":"87","author":"Zhang","year":"2010","journal-title":"Diabetes Res Clin Pract"},{"key":"10.1016\/j.dsx.2014.05.001_bib0140","doi-asserted-by":"crossref","first-page":"1","DOI":"10.2337\/diabetes.48.1.1","article-title":"Role of oxidative stress in diabetic complications: a new perspective on an old paradigm","volume":"48","author":"Baynes","year":"1999","journal-title":"Diabetes"},{"issue":"1","key":"10.1016\/j.dsx.2014.05.001_bib0145","first-page":"1","article-title":"Oxidative stress and its complications in diabetes mellitus","volume":"4","author":"Goycheva","year":"2006","journal-title":"Trakia J Sci"},{"key":"10.1016\/j.dsx.2014.05.001_bib0150","doi-asserted-by":"crossref","first-page":"370","DOI":"10.3109\/03630260903212175","article-title":"Oxidative stress, diabetes, and diabetic complications","volume":"33","author":"Wei","year":"2009","journal-title":"Hemoglobin"},{"key":"10.1016\/j.dsx.2014.05.001_bib0155","doi-asserted-by":"crossref","first-page":"1058","DOI":"10.1161\/CIRCRESAHA.110.223545","article-title":"Oxidative stress and diabetic complications","volume":"107","author":"Giacco","year":"2010","journal-title":"Circ Res"},{"key":"10.1016\/j.dsx.2014.05.001_bib0160","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1016\/S0140-6736(94)92211-X","article-title":"Free radicals, antioxidants, and human disease: curiosity, cause, or consequence?","volume":"344","author":"Halliwell","year":"1994","journal-title":"Lancet"},{"key":"10.1016\/j.dsx.2014.05.001_bib0165","doi-asserted-by":"crossref","first-page":"1615","DOI":"10.2337\/diabetes.54.6.1615","article-title":"The pathobiology of diabetic complications: a unifying mechanism","volume":"54","author":"Brownlee","year":"2005","journal-title":"Diabetes"},{"key":"10.1016\/j.dsx.2014.05.001_bib0170","doi-asserted-by":"crossref","first-page":"42351","DOI":"10.1074\/jbc.R400019200","article-title":"Chronic oxidative stress as a central mechanism for glucose toxicity in pancreatic islet beta cells in diabetes","volume":"279","author":"Robertson","year":"2004","journal-title":"J Biol Chem"},{"key":"10.1016\/j.dsx.2014.05.001_bib0175","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1007\/s12013-007-0026-5","article-title":"Chronic oxidative stress as a mechanism for glucose toxicity of the beta cell in type 2 diabetes","volume":"48","author":"Robertson","year":"2007","journal-title":"Cell Biochem Biophys"},{"key":"10.1016\/j.dsx.2014.05.001_bib0180","first-page":"794","article-title":"Free radicals and antioxidants in human health: current status and future prospects","volume":"52","author":"Devasagayam","year":"2004","journal-title":"J Assoc Phys India"},{"key":"10.1016\/j.dsx.2014.05.001_bib0185","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1186\/1475-2840-4-5","article-title":"Oxidative stress and the use of antioxidants in diabetes: linking basic science to clinical practice","volume":"4","author":"Johansen","year":"2005","journal-title":"Cardiovasc Diabetol"},{"key":"10.1016\/j.dsx.2014.05.001_bib0190","first-page":"75","article-title":"Radicals and antioxidants in relation to human and animal health: a case for functional feeding","volume":"69","author":"Demeyer","year":"2004","journal-title":"Commun Agric Appl Biol Sci"},{"key":"10.1016\/j.dsx.2014.05.001_bib0195","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1146\/annurev.nu.16.070196.000341","article-title":"Antioxidants in human health and disease","volume":"16","author":"Halliwell","year":"1996","journal-title":"Annu Rev Nutr"},{"key":"10.1016\/j.dsx.2014.05.001_bib0200","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1053\/meta.2001.19432","article-title":"Taurine and osmoregulation: platelet taurine content, uptake, and release in type 2 diabetic patients","volume":"50","author":"De Luca","year":"2001","journal-title":"Metabolism"},{"key":"10.1016\/j.dsx.2014.05.001_bib0205","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1016\/0026-0495(84)90141-0","article-title":"Sulfur amino acid metabolism in juvenile-onset nonketotic and ketotic diabetic patients","volume":"33","author":"Martensson","year":"1984","journal-title":"Metabolism"},{"key":"10.1016\/j.dsx.2014.05.001_bib0210","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1002\/dmrr.229","article-title":"The role of taurine in diabetes and the development of diabetic complications","volume":"17","author":"Hansen","year":"2001","journal-title":"Diabetes Metab Res Rev"},{"key":"10.1016\/j.dsx.2014.05.001_bib0215","doi-asserted-by":"crossref","first-page":"2652","DOI":"10.2337\/dc07-0872","article-title":"Taurine intestinal absorption and renal excretion test in diabetic patients: a pilot study","volume":"30","author":"Merheb","year":"2007","journal-title":"Diabetes Care"},{"key":"10.1016\/j.dsx.2014.05.001_bib0220","first-page":"63","article-title":"Taurine\u2013diabetes interaction: from involvement to protection","volume":"21","author":"Kim","year":"2007","journal-title":"J Biol Regul Homeost Agents"},{"key":"10.1016\/j.dsx.2014.05.001_bib0225","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0885-4505(90)90002-I","article-title":"Supplemental taurine in diabetic rats: effects on plasma glucose and triglycerides","volume":"43","author":"Goodman","year":"1990","journal-title":"Biochem Med Metab Biol"},{"key":"10.1016\/j.dsx.2014.05.001_bib0230","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1016\/0022-2828(79)90407-3","article-title":"Changes in taurine content in heart and other organs of diabetic rats","volume":"11","author":"Reibel","year":"1979","journal-title":"J Mol Cell Cardiol"},{"key":"10.1016\/j.dsx.2014.05.001_bib0235","doi-asserted-by":"crossref","first-page":"1209","DOI":"10.1177\/41.8.8331284","article-title":"Immunohistochemical localization of taurine in rat renal tissue: studies in experimental disease states","volume":"41","author":"Trachtman","year":"1993","journal-title":"J Histochem Cytochem"},{"key":"10.1016\/j.dsx.2014.05.001_bib0240","doi-asserted-by":"crossref","first-page":"1167","DOI":"10.1007\/BF02532391","article-title":"Effect of diabetes on levels and uptake of putative amino acid neurotransmitters in rat retina and retinal pigment epithelium","volume":"21","author":"Vilchis","year":"1996","journal-title":"Neurochem Res"},{"key":"10.1016\/j.dsx.2014.05.001_bib0245","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1016\/1056-8727(93)90023-R","article-title":"Taurine prevents galactose-induced cataracts","volume":"7","author":"Malone","year":"1993","journal-title":"J Diabetes Complications"},{"key":"10.1016\/j.dsx.2014.05.001_bib0250","doi-asserted-by":"crossref","first-page":"608","DOI":"10.1007\/BF00404069","article-title":"Osmotically-induced nerve taurine depletion and the compatible osmolyte hypothesis in experimental diabetic neuropathy in the rat","volume":"36","author":"Stevens","year":"1993","journal-title":"Diabetologia"},{"key":"10.1016\/j.dsx.2014.05.001_bib0255","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1006\/exnr.2000.7591","article-title":"Depletion of taurine in experimental diabetic neuropathy: implications for nerve metabolic, vascular, and functional deficits","volume":"168","author":"Pop-Busui","year":"2001","journal-title":"Exp Neurol"},{"key":"10.1016\/j.dsx.2014.05.001_bib0260","doi-asserted-by":"crossref","first-page":"949","DOI":"10.1126\/science.1138364","article-title":"Retinal degeneration associated with taurine deficiency in the cat","volume":"188","author":"Hayes","year":"1975","journal-title":"Science"},{"key":"10.1016\/j.dsx.2014.05.001_bib0265","doi-asserted-by":"crossref","first-page":"764","DOI":"10.1126\/science.3616607","article-title":"Myocardial failure in cats associated with low plasma taurine: a reversible cardiomyopathy","volume":"237","author":"Pion","year":"1987","journal-title":"Science"},{"key":"10.1016\/j.dsx.2014.05.001_bib0270","doi-asserted-by":"crossref","first-page":"S166","DOI":"10.1093\/jn\/121.suppl_11.S166","article-title":"Dietary taurine and feline reproduction and development","volume":"121","author":"Sturman","year":"1991","journal-title":"J Nutr"},{"key":"10.1016\/j.dsx.2014.05.001_bib0275","doi-asserted-by":"crossref","first-page":"1529","DOI":"10.1007\/s00726-011-0883-5","article-title":"The potential usefulness of taurine on diabetes mellitus and its complications","volume":"42","author":"Ito","year":"2012","journal-title":"Amino Acids"},{"key":"10.1016\/j.dsx.2014.05.001_bib0280","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1089\/dia.2010.0146","article-title":"Role of chronic and acute hyperglycemia in the development of diabetes complications","volume":"13","author":"Marcovecchio","year":"2011","journal-title":"Diabetes Technol Ther"},{"key":"10.1016\/j.dsx.2014.05.001_bib0285","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1515\/bchm2.1935.235.3-4.115","article-title":"Uber die physiologische wirkung des asterubins and anderer, zum tiel neu dargestellter, schwefelhaltiger guanidinderivate","volume":"235","author":"Ackerman","year":"1935","journal-title":"Z Physiol Chem"},{"key":"10.1016\/j.dsx.2014.05.001_bib0290","first-page":"669","article-title":"The potentiation of insulin by sulfones","volume":"26","author":"Macallum","year":"1942","journal-title":"Can Chem Process"},{"key":"10.1016\/j.dsx.2014.05.001_bib0295","first-page":"293","article-title":"Influence exerted by taurine on the utilization of glucose by the rat","volume":"46","author":"Donadio","year":"1964","journal-title":"Bull Soc Chim Biol (Paris)"},{"key":"10.1016\/j.dsx.2014.05.001_bib0300","first-page":"503","article-title":"Insulin-like effects of taurine","volume":"22","author":"Dokshina","year":"1976","journal-title":"Vopr Med Khim"},{"key":"10.1016\/j.dsx.2014.05.001_bib0305","doi-asserted-by":"crossref","first-page":"2835","DOI":"10.1016\/0006-2952(84)90204-1","article-title":"Hypoglycemic properties of taurine: not mediated by enhanced insulin release","volume":"33","author":"Kulakowski","year":"1984","journal-title":"Biochem Pharmacol"},{"key":"10.1016\/j.dsx.2014.05.001_bib0310","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1007\/978-1-4615-0077-3_13","article-title":"Hypoglycemic effects of taurine in the alloxan-treated rabbit, a model for type 1 diabetes","volume":"526","author":"Tenner","year":"2003","journal-title":"Adv Exp Med Biol"},{"key":"10.1016\/j.dsx.2014.05.001_bib0315","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1016\/j.taap.2011.11.009","article-title":"Taurine exerts hypoglycemic effect in alloxan-induced diabetic rats, improves insulin-mediated glucose transport signaling pathway in heart and ameliorates cardiac oxidative stress and apoptosis","volume":"258","author":"Das","year":"2012","journal-title":"Toxicol Appl Pharmacol"},{"key":"10.1016\/j.dsx.2014.05.001_bib0320","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1139\/y83-070","article-title":"Potentiation of the actions of insulin by taurine","volume":"61","author":"Lampson","year":"1983","journal-title":"Can J Physiol Pharmacol"},{"key":"10.1016\/j.dsx.2014.05.001_bib0325","first-page":"95","article-title":"Does taurine bind to the insulin binding site of the insulin receptor?","volume":"351","author":"Kulakowski","year":"1990","journal-title":"Prog Clin Biol Res"},{"key":"10.1016\/j.dsx.2014.05.001_bib0330","first-page":"521","article-title":"Effect of glycine in streptozotocin-induced diabetic rats","volume":"134","author":"Alvarado-Vasquez","year":"2003","journal-title":"Comp Biochem Physiol C: Toxicol Pharmacol"},{"key":"10.1016\/j.dsx.2014.05.001_bib0335","doi-asserted-by":"crossref","first-page":"499","DOI":"10.2337\/diabetes.52.2.499","article-title":"Comparative trial of N-acetyl-cysteine, taurine, and oxerutin on skin and kidney damage in long-term experimental diabetes","volume":"52","author":"Odetti","year":"2003","journal-title":"Diabetes"},{"key":"10.1016\/j.dsx.2014.05.001_bib0340","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1007\/s00726-004-0108-2","article-title":"Long-term taurine supplementation reduces mortality rate in streptozotocin-induced diabetic rats","volume":"27","author":"Di Leo","year":"2004","journal-title":"Amino Acids"},{"key":"10.1016\/j.dsx.2014.05.001_bib0345","first-page":"605","article-title":"Study on the intervening mechanism of taurine on streptozotocin-induced diabetic cataracts","volume":"39","author":"Song","year":"2003","journal-title":"Zhonghua Yan Ke Za Zhi"},{"key":"10.1016\/j.dsx.2014.05.001_bib0350","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1007\/978-1-4899-0117-0_13","article-title":"Effect of taurine supplementation on the lipid peroxide formation and the activities of glutathione-related enzymes in the liver and islet of type I and II diabetic model mice","volume":"442","author":"Lim","year":"1998","journal-title":"Adv Exp Med Biol"},{"key":"10.1016\/j.dsx.2014.05.001_bib0355","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1007\/s10517-008-0258-4","article-title":"Protective effect of taurine on rats with experimental insulin-dependent diabetes mellitus","volume":"146","author":"Gavrovskaya","year":"2008","journal-title":"Bull Exp Biol Med"},{"key":"10.1016\/j.dsx.2014.05.001_bib0360","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1016\/j.biochi.2008.09.006","article-title":"Hypoglycaemic, antioxidative and nephroprotective effects of taurine in alloxan diabetic rabbits","volume":"91","author":"Winiarska","year":"2009","journal-title":"Biochimie"},{"key":"10.1016\/j.dsx.2014.05.001_bib0365","doi-asserted-by":"crossref","first-page":"1008","DOI":"10.1152\/ajpendo.00008.2004","article-title":"Taurine increases glucose sensitivity of UCP2-overexpressing beta-cells by ameliorating mitochondrial metabolism","volume":"287","author":"Han","year":"2004","journal-title":"Am J Physiol Endocrinol Metab"},{"key":"10.1016\/j.dsx.2014.05.001_bib0370","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1007\/978-0-387-75681-3_36","article-title":"Taurine supplementation and pancreatic remodeling","volume":"643","author":"El Idrissi","year":"2009","journal-title":"Adv Exp Med Biol"},{"key":"10.1016\/j.dsx.2014.05.001_bib0375","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1186\/1758-5996-2-46","article-title":"Effect of taurine supplementation on hyperhomocysteinemia and markers of oxidative stress in high fructose diet induced insulin resistance","volume":"2","author":"El Mesallamy","year":"2010","journal-title":"Diabetol Metab Syndr"},{"key":"10.1016\/j.dsx.2014.05.001_bib0380","doi-asserted-by":"crossref","first-page":"1077","DOI":"10.1038\/oby.2004.135","article-title":"Taurine alters respiratory gas exchange and nutrient metabolism in type 2 diabetic rats","volume":"12","author":"Harada","year":"2004","journal-title":"Obes Res"},{"key":"10.1016\/j.dsx.2014.05.001_bib0385","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1093\/ajcn\/71.1.54","article-title":"Taurine improves insulin sensitivity in the Otsuka Long-Evans Tokushima Fatty rat, a model of spontaneous type 2 diabetes","volume":"71","author":"Nakaya","year":"2000","journal-title":"Am J Clin Nutr"},{"key":"10.1016\/j.dsx.2014.05.001_bib0390","first-page":"82","article-title":"Effect of taurine on biomarkers of oxidative stress in tissues of fructose-fed insulin-resistant rats","volume":"46","author":"Nandhini","year":"2005","journal-title":"Singapore Med J"},{"key":"10.1016\/j.dsx.2014.05.001_bib0395","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1007\/978-1-4899-0182-8_63","article-title":"First experiments in taurine administration for diabetes mellitus. The effect on erythrocyte membranes","volume":"403","author":"Elizarova","year":"1996","journal-title":"Adv Exp Med Biol"},{"key":"10.1016\/j.dsx.2014.05.001_bib0400","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1007\/978-1-4615-0077-3_12","article-title":"The effect of taurine supplementation on patients with type 2 diabetes mellitus","volume":"526","author":"Chauncey","year":"2003","journal-title":"Adv Exp Med Biol"},{"key":"10.1016\/j.dsx.2014.05.001_bib0405","doi-asserted-by":"crossref","first-page":"1239","DOI":"10.1038\/sj.ejcn.1601955","article-title":"Effect of taurine treatment on insulin secretion and action, and on serum lipid levels in overweight men with a genetic predisposition for type II diabetes mellitus","volume":"58","author":"Brons","year":"2004","journal-title":"Eur J Clin Nutr"},{"key":"10.1016\/j.dsx.2014.05.001_bib0410","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1007\/s00125-007-0859-x","article-title":"Oral taurine but not N-acetylcysteine ameliorates NEFA-induced impairment in insulin sensitivity and beta cell function in obese and overweight, non-diabetic men","volume":"51","author":"Xiao","year":"2008","journal-title":"Diabetologia"},{"key":"10.1016\/j.dsx.2014.05.001_bib0415","series-title":"Taurine in health and disease","first-page":"167","article-title":"Taurine and metabolic disease","author":"Hansen","year":"2012"},{"key":"10.1016\/j.dsx.2014.05.001_bib0420","first-page":"RA130","article-title":"Diabetes mellitus: complications and therapeutics","volume":"12","author":"Tripathi","year":"2006","journal-title":"Med Sci Monit"},{"key":"10.1016\/j.dsx.2014.05.001_bib0425","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1016\/j.diabet.2010.06.002","article-title":"Cardiovascular complications in type 1 diabetes mellitus","volume":"36","author":"Brindisi","year":"2010","journal-title":"Diabetes Metab"},{"key":"10.1016\/j.dsx.2014.05.001_bib0430","series-title":"Definition and diagnosis of diabetes mellitus and intermediate hyperglycemia: report of a WHO\/IDF consultation","author":"World Health Organization","year":"2006"},{"key":"10.1016\/j.dsx.2014.05.001_bib0435","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1159\/000324934","article-title":"Epidemiology of diabetic nephropathy","volume":"170","author":"Reutens","year":"2011","journal-title":"Contrib Nephrol"},{"key":"10.1016\/j.dsx.2014.05.001_bib0440","article-title":"Dual therapy of vildagliptin and telmisartan on diabetic nephropathy in experimentally induced type 2 diabetes mellitus rats","author":"Sharma","year":"2013","journal-title":"J Renin Angiotensin Aldosterone Syst"},{"issue":"Suppl. 10","key":"10.1016\/j.dsx.2014.05.001_bib0445","first-page":"S75","article-title":"The discovery of diabetic nephropathy: from small print to centre stage","volume":"19","author":"Cameron","year":"2006","journal-title":"J Nephrol"},{"key":"10.1016\/j.dsx.2014.05.001_bib0450","first-page":"232","article-title":"Network-centric analysis of genetic predisposition in diabetic nephropathy","volume":"15","author":"Ntemka","year":"2011","journal-title":"Hippokratia"},{"issue":"1","key":"10.1016\/j.dsx.2014.05.001_bib0455","first-page":"38","article-title":"Endothelin receptor antagonists in diabetic nephropathy","volume":"6","author":"Wenzel","year":"2012","journal-title":"Eur Nephrol"},{"issue":"Suppl. 1","key":"10.1016\/j.dsx.2014.05.001_bib0460","first-page":"S79","article-title":"Nephropathy in diabetes","volume":"27","author":"Molitch","year":"2004","journal-title":"Diabetes Care"},{"key":"10.1016\/j.dsx.2014.05.001_bib0465","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1038\/ncpendmet0894","article-title":"The pathogenesis of diabetic nephropathy","volume":"4","author":"Dronavalli","year":"2008","journal-title":"Nat Clin Pract Endocrinol Metab"},{"key":"10.1016\/j.dsx.2014.05.001_bib0470","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1111\/j.1365-2362.2004.01429.x","article-title":"New insights into the pathophysiology of diabetic nephropathy: from haemodynamics to molecular pathology","volume":"34","author":"Wolf","year":"2004","journal-title":"Eur J Clin Invest"},{"issue":"2","key":"10.1016\/j.dsx.2014.05.001_bib0475","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/S2211-9477(12)70005-5","article-title":"Pathophysiology of diabetic nephropathy","volume":"1","author":"Vinod","year":"2012","journal-title":"Clin Queries Nephrol"},{"key":"10.1016\/j.dsx.2014.05.001_bib0480","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1053\/j.ackd.2005.01.001","article-title":"Role of oxidative stress in diabetic nephropathy","volume":"12","author":"Vasavada","year":"2005","journal-title":"Adv Chronic Kidney Dis"},{"key":"10.1016\/j.dsx.2014.05.001_bib0485","doi-asserted-by":"crossref","first-page":"1446","DOI":"10.2337\/db08-0057","article-title":"Oxidative stress as a major culprit in kidney disease in diabetes","volume":"57","author":"Forbes","year":"2008","journal-title":"Diabetes"},{"key":"10.1016\/j.dsx.2014.05.001_bib0490","doi-asserted-by":"crossref","first-page":"1185","DOI":"10.1007\/s00726-010-0771-4","article-title":"Glycation in diabetic nephropathy","volume":"42","author":"Forbes","year":"2012","journal-title":"Amino Acids"},{"key":"10.1016\/j.dsx.2014.05.001_bib0495","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1152\/physrev.00045.2011","article-title":"Mechanisms of diabetic complications","volume":"93","author":"Forbes","year":"2013","journal-title":"Physiol Rev"},{"key":"10.1016\/j.dsx.2014.05.001_bib0500","first-page":"510","article-title":"Diabetic nephropathy: etiologic and therapeutic considerations","volume":"3","author":"DeFronzo","year":"1995","journal-title":"Diabetes Rev"},{"key":"10.1016\/j.dsx.2014.05.001_bib0505","doi-asserted-by":"crossref","first-page":"1080","DOI":"10.1016\/S0140-6736(95)91747-0","article-title":"Prevention of diabetic renal disease with special reference to microalbuminuria","volume":"346","author":"Mogensen","year":"1995","journal-title":"Lancet"},{"key":"10.1016\/j.dsx.2014.05.001_bib0510","doi-asserted-by":"crossref","first-page":"2249","DOI":"10.1007\/s00726-012-1314-y","article-title":"The role of taurine in renal disorders","volume":"43","author":"Han","year":"2012","journal-title":"Amino Acids"},{"key":"10.1016\/j.dsx.2014.05.001_bib0515","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1038\/ki.1994.2","article-title":"Light- and electronmicroscopic distribution of taurine, an organic osmolyte, in rat renal tubule cells","volume":"45","author":"Amiry-Moghaddam","year":"1994","journal-title":"Kidney Int"},{"key":"10.1016\/j.dsx.2014.05.001_bib0520","first-page":"F429","article-title":"Taurine ameliorates chronic streptozocin-induced diabetic nephropathy in rats","volume":"269","author":"Trachtman","year":"1995","journal-title":"Am J Physiol"},{"key":"10.1016\/j.dsx.2014.05.001_bib0525","doi-asserted-by":"crossref","first-page":"944","DOI":"10.1016\/S0891-5849(98)00276-7","article-title":"Melatonin and taurine reduce early glomerulopathy in diabetic rats","volume":"26","author":"Ha","year":"1999","journal-title":"Free Radic Biol Med"},{"key":"10.1016\/j.dsx.2014.05.001_bib0530","doi-asserted-by":"crossref","first-page":"443","DOI":"10.2310\/6650.2002.32504","article-title":"Taurine prevents apoptosis induced by high ambient glucose in human tubule renal cells","volume":"50","author":"Verzola","year":"2002","journal-title":"J Investig Med"},{"key":"10.1016\/j.dsx.2014.05.001_bib0535","doi-asserted-by":"crossref","first-page":"S250","DOI":"10.1097\/01.ASN.0000077412.07578.44","article-title":"Effects of antioxidants in diabetes-induced oxidative stress in the glomeruli of diabetic rats","volume":"14","author":"Koya","year":"2003","journal-title":"J Am Soc Nephrol"},{"key":"10.1016\/j.dsx.2014.05.001_bib0540","doi-asserted-by":"crossref","first-page":"1831","DOI":"10.1007\/s00125-004-1535-z","article-title":"Taurine supplement in early life altered islet morphology, decreased insulitis and delayed the onset of diabetes in non-obese diabetic mice","volume":"47","author":"Arany","year":"2004","journal-title":"Diabetologia"},{"key":"10.1016\/j.dsx.2014.05.001_bib0545","doi-asserted-by":"crossref","first-page":"1762","DOI":"10.1111\/j.1523-1755.2005.00274.x","article-title":"Reactive oxygen species mediate high glucose-induced plasminogen activator inhibitor-1 up-regulation in mesangial cells and in diabetic kidney","volume":"67","author":"Lee","year":"2005","journal-title":"Kidney Int"},{"key":"10.1016\/j.dsx.2014.05.001_bib0550","doi-asserted-by":"crossref","first-page":"1072","DOI":"10.1152\/ajprenal.00020.2007","article-title":"Antioxidants attenuate high glucose-induced hypertrophic growth in renal tubular epithelial cells","volume":"293","author":"Huang","year":"2007","journal-title":"Am J Physiol Renal Physiol"},{"key":"10.1016\/j.dsx.2014.05.001_bib0555","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1016\/j.taap.2008.09.002","article-title":"Effect of taurine on advanced glycation end products-induced hypertrophy in renal tubular epithelial cells","volume":"233","author":"Huang","year":"2008","journal-title":"Toxicol Appl Pharmacol"},{"key":"10.1016\/j.dsx.2014.05.001_bib0560","first-page":"E35","article-title":"Taurine administration after appearance of proteinuria retards progression of diabetic nephropathy in rats","volume":"54","author":"Higo","year":"2008","journal-title":"Kobe J Med Sci"},{"key":"10.1016\/j.dsx.2014.05.001_bib0565","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1080\/08860220802272563","article-title":"The protective effects of taurine against early renal injury in STZ-induced diabetic rats, correlated with inhibition of renal LOX-1-mediated ICAM-1 expression","volume":"30","author":"Wang","year":"2008","journal-title":"Ren Fail"},{"key":"10.1016\/j.dsx.2014.05.001_bib0570","doi-asserted-by":"crossref","first-page":"556","DOI":"10.2337\/dc11-1909","article-title":"Global prevalence and major risk factors of diabetic retinopathy","volume":"35","author":"Yau","year":"2012","journal-title":"Diabetes Care"},{"issue":"S1","key":"10.1016\/j.dsx.2014.05.001_bib0575","doi-asserted-by":"crossref","first-page":"S90","DOI":"10.2337\/diacare.25.2007.S90","article-title":"Diabetic retinopathy","volume":"25","author":"American Diabetes Association","year":"2002","journal-title":"Diabetes Care"},{"key":"10.1016\/j.dsx.2014.05.001_bib0580","doi-asserted-by":"crossref","first-page":"2540","DOI":"10.2337\/diacare.27.10.2540","article-title":"Diabetic retinopathy","volume":"27","author":"Fong","year":"2004","journal-title":"Diabetes Care"},{"key":"10.1016\/j.dsx.2014.05.001_bib0585","series-title":"National Diabetes Data Group, Diabetes in America","first-page":"293","article-title":"Vision disorders in diabetes","author":"Klein","year":"1995"},{"key":"10.1016\/j.dsx.2014.05.001_bib0590","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1001\/jama.2010.1111","article-title":"Prevalence of diabetic retinopathy in the United States, 2005\u20132008","volume":"304","author":"Zhang","year":"2010","journal-title":"JAMA"},{"key":"10.1016\/j.dsx.2014.05.001_bib0595","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1113\/jphysiol.2012.243147","article-title":"Taurine activates delayed rectifier Kv channels via a metabotropic pathway in retinal neurons","volume":"591","author":"Bulley","year":"2013","journal-title":"J Physiol"},{"key":"10.1016\/j.dsx.2014.05.001_bib0600","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1007\/s11064-008-9763-0","article-title":"Dietary taurine supplementation prevents glial alterations in retina of diabetic rats","volume":"34","author":"Zeng","year":"2009","journal-title":"Neurochem Res"},{"key":"10.1016\/j.dsx.2014.05.001_bib0605","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1016\/j.mcn.2010.06.010","article-title":"Effects of taurine on glutamate uptake and degradation in Muller cells under diabetic conditions via antioxidant mechanism","volume":"45","author":"Zeng","year":"2010","journal-title":"Mol Cell Neurosci"},{"key":"10.1016\/j.dsx.2014.05.001_bib0610","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1007\/s00726-002-0202-2","article-title":"Chronic taurine supplementation ameliorates oxidative stress and Na+ K+ ATPase impairment in the retina of diabetic rats","volume":"23","author":"Di Leo","year":"2002","journal-title":"Amino Acids"},{"key":"10.1016\/j.dsx.2014.05.001_bib0615","first-page":"323784","article-title":"Reversal of the caspase-dependent apoptotic cytotoxicity pathway by taurine from Lycium barbarum (Goji Berry) in human retinal pigment epithelial cells: potential benefit in diabetic retinopathy","author":"Song","year":"2012","journal-title":"Evid Based Complementary Altern Med"},{"key":"10.1016\/j.dsx.2014.05.001_bib0620","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/j.brainres.2009.04.054","article-title":"Taurine protects transformed rat retinal ganglion cells from hypoxia-induced apoptosis by preventing mitochondrial dysfunction","volume":"1279","author":"Chen","year":"2009","journal-title":"Brain Res"},{"key":"10.1016\/j.dsx.2014.05.001_bib0625","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1007\/978-1-4614-6130-2_6","article-title":"Taurine is a crucial factor to preserve retinal ganglion cell survival","volume":"775","author":"Froger","year":"2013","journal-title":"Adv Exp Med Biol"},{"key":"10.1016\/j.dsx.2014.05.001_bib0630","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1016\/S1474-4422(12)70065-0","article-title":"Diabetic neuropathy: clinical manifestations and current treatments","volume":"11","author":"Callaghan","year":"2012","journal-title":"Lancet Neurol"},{"key":"10.1016\/j.dsx.2014.05.001_bib0635","doi-asserted-by":"crossref","first-page":"536","DOI":"10.1097\/WCO.0b013e328357a797","article-title":"Diabetic neuropathy: one disease or two?","volume":"25","author":"Callaghan","year":"2012","journal-title":"Curr Opin Neurol"},{"key":"10.1016\/j.dsx.2014.05.001_bib0640","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1038\/ncpendmet0142","article-title":"Diabetic neuropathies: clinical manifestations and current treatment options","volume":"2","author":"Vinik","year":"2006","journal-title":"Nat Clin Pract Endocrinol Metab"},{"key":"10.1016\/j.dsx.2014.05.001_bib0645","doi-asserted-by":"crossref","first-page":"550","DOI":"10.4158\/EP.13.5.550","article-title":"Clinical manifestations and current treatment options for diabetic neuropathies","volume":"13","author":"Casellini","year":"2007","journal-title":"Endocr Pract"},{"issue":"Suppl. 2","key":"10.1016\/j.dsx.2014.05.001_bib0650","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1111\/j.1529-8027.2012.00391.x","article-title":"Treatments for diabetic neuropathy","volume":"17","author":"Bril","year":"2012","journal-title":"J Peripher Nerv Syst"},{"key":"10.1016\/j.dsx.2014.05.001_bib0655","doi-asserted-by":"crossref","first-page":"1167","DOI":"10.1016\/S1388-2457(03)00025-7","article-title":"Diabetic neuropathy: a review emphasizing diagnostic methods","volume":"114","author":"Perkins","year":"2003","journal-title":"Clin Neurophysiol"},{"key":"10.1016\/j.dsx.2014.05.001_bib0660","doi-asserted-by":"crossref","first-page":"880","DOI":"10.1124\/pr.111.005314","article-title":"Diabetic peripheral neuropathy: should a chaperone accompany our therapeutic approach?","volume":"64","author":"Farmer","year":"2012","journal-title":"Pharmacol Rev"},{"key":"10.1016\/j.dsx.2014.05.001_bib0665","doi-asserted-by":"crossref","first-page":"E620","DOI":"10.1152\/ajpendo.00287.2009","article-title":"Oxidative stress and dysregulation of the taurine transporter in high-glucose-exposed human Schwann cells: implications for pathogenesis of diabetic neuropathy","volume":"297","author":"Askwith","year":"2009","journal-title":"Am J Physiol Endocrinol Metab"},{"key":"10.1016\/j.dsx.2014.05.001_bib0670","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1006\/exnr.2001.7789","article-title":"Taurine counteracts oxidative stress and nerve growth factor deficit in early experimental diabetic neuropathy","volume":"172","author":"Obrosova","year":"2001","journal-title":"Exp Neurol"},{"key":"10.1016\/j.dsx.2014.05.001_bib0675","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/j.expneurol.2011.09.010","article-title":"Taurine reduces nitrosative stress and nitric oxide synthase expression in high glucose-exposed human Schwann cells","volume":"233","author":"Askwith","year":"2012","journal-title":"Exp Neurol"},{"key":"10.1016\/j.dsx.2014.05.001_bib0680","doi-asserted-by":"crossref","first-page":"E29","DOI":"10.1152\/ajpendo.00168.2004","article-title":"Taurine replacement attenuates hyperalgesia and abnormal calcium signaling in sensory neurons of STZ-D rats","volume":"288","author":"Li","year":"2005","journal-title":"Am J Physiol Endocrinol Metab"},{"key":"10.1016\/j.dsx.2014.05.001_bib0685","doi-asserted-by":"crossref","first-page":"630","DOI":"10.1007\/s12630-011-9504-8","article-title":"Antinociceptive effect of intrathecal administration of taurine in rat models of neuropathic pain","volume":"58","author":"Terada","year":"2011","journal-title":"Can J Anaesth"},{"key":"10.1016\/j.dsx.2014.05.001_bib0690","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1136\/bmj.38922.650521.80","article-title":"Prevention and early detection of vascular complications of diabetes","volume":"333","author":"Marshall","year":"2006","journal-title":"BMJ"},{"key":"10.1016\/j.dsx.2014.05.001_bib0695","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1007\/978-1-4614-5441-0_13","article-title":"Glycemic variability in type 2 diabetes mellitus: oxidative stress and macrovascular complications","volume":"771","author":"Johnson","year":"2012","journal-title":"Adv Exp Med Biol"},{"key":"10.1016\/j.dsx.2014.05.001_bib0700","doi-asserted-by":"crossref","first-page":"977","DOI":"10.1056\/NEJM199309303291401","article-title":"The effect 2 of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus","volume":"329","author":"Diabetes Control and Complication Trial (DCCT) Research Group","year":"1993","journal-title":"N Engl J Med"},{"key":"10.1016\/j.dsx.2014.05.001_bib0705","series-title":"National Diabetes Fact Sheet","author":"Centers for Disease Control and Prevention","year":"2011"},{"key":"10.1016\/j.dsx.2014.05.001_bib0710","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1016\/S1056-8727(00)00132-X","article-title":"Diabetes mellitus: a hypercoagulable state","volume":"15","author":"Carr","year":"2001","journal-title":"J Diabetes Complications"},{"key":"10.1016\/j.dsx.2014.05.001_bib0715","first-page":"84","article-title":"The proinflammatory and hypercoagulable state of diabetes mellitus","volume":"6","author":"Aras","year":"2005","journal-title":"Rev Cardiovasc Med"},{"key":"10.1016\/j.dsx.2014.05.001_bib0720","doi-asserted-by":"crossref","first-page":"963","DOI":"10.1038\/sj.bjp.0703393","article-title":"Endothelial dysfunction in diabetes","volume":"130","author":"De Vriese","year":"2000","journal-title":"Br J Pharmacol"},{"key":"10.1016\/j.dsx.2014.05.001_bib0725","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1038\/ncpendmet0366","article-title":"Mechanisms of disease: endothelial dysfunction in insulin resistance and diabetes","volume":"3","author":"Rask-Madsen","year":"2007","journal-title":"Nat Clin Pract Endocrinol Metab"},{"key":"10.1016\/j.dsx.2014.05.001_bib0730","first-page":"910","article-title":"Taurine and glucose metabolism: a review","volume":"25","author":"De la Puerta","year":"2010","journal-title":"Nutr Hosp"},{"key":"10.1016\/j.dsx.2014.05.001_bib0735","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1016\/S0008-6363(00)00025-0","article-title":"The role of taurine in the pathogenesis of the cardiomyopathy of insulin-dependent diabetes mellitus","volume":"46","author":"Militante","year":"2000","journal-title":"Cardiovasc Res"},{"key":"10.1016\/j.dsx.2014.05.001_bib0740","doi-asserted-by":"crossref","first-page":"1123","DOI":"10.1161\/01.RES.87.12.1123","article-title":"Myocardial cell death in human diabetes","volume":"87","author":"Frustaci","year":"2000","journal-title":"Circ Res"},{"key":"10.1016\/j.dsx.2014.05.001_bib0745","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/S0014-2999(00)00483-0","article-title":"Taurine attenuates hypertrophy induced by angiotensin II in cultured neonatal rat cardiac myocytes","volume":"403","author":"Azuma","year":"2000","journal-title":"Eur J Pharmacol"},{"key":"10.1016\/j.dsx.2014.05.001_bib0750","doi-asserted-by":"crossref","first-page":"1251","DOI":"10.1039\/c2fo30117b","article-title":"Mechanism of the protective action of taurine in toxin and drug induced organ pathophysiology and diabetic complications: a review","volume":"3","author":"Das","year":"2012","journal-title":"Food Funct"},{"key":"10.1016\/j.dsx.2014.05.001_bib0755","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1007\/978-0-387-75681-3_43","article-title":"Effect of taurine supplementation on plasma homocysteine levels of the middle-aged Korean women","volume":"643","author":"Ahn","year":"2009","journal-title":"Adv Exp Med Biol"},{"key":"10.1016\/j.dsx.2014.05.001_bib0760","first-page":"e17","article-title":"Effects of amino acid supplementation on myocardial cell damage and cardiac function in diabetes","volume":"16","author":"Tappia","year":"2011","journal-title":"Exp Clin Cardiol"},{"key":"10.1016\/j.dsx.2014.05.001_bib0765","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1177\/1479164110375971","article-title":"Two weeks taurine supplementation reverses endothelial dysfunction in young male type 1 diabetics","volume":"7","author":"Moloney","year":"2010","journal-title":"Diab Vasc Dis Res"},{"key":"10.1016\/j.dsx.2014.05.001_bib0770","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.ejphar.2008.08.031","article-title":"Taurine rescues vascular endothelial dysfunction in streptozocin-induced diabetic rats: correlated with downregulation of LOX-1 and ICAM-1 expression on aortas","volume":"597","author":"Wang","year":"2008","journal-title":"Eur J Pharmacol"},{"issue":"3","key":"10.1016\/j.dsx.2014.05.001_bib0775","doi-asserted-by":"crossref","first-page":"160","DOI":"10.2337\/diaspect.21.3.160","article-title":"The pathophysiology of cardiovascular disease and diabetes: beyond blood pressure and lipids","volume":"21","author":"Dokken","year":"2008","journal-title":"Diabetes Spectr"},{"key":"10.1016\/j.dsx.2014.05.001_bib0780","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1002\/mnfr.201100799","article-title":"The effect of taurine on cholesterol metabolism","volume":"56","author":"Chen","year":"2012","journal-title":"Mol Nutr Food Res"},{"key":"10.1016\/j.dsx.2014.05.001_bib0785","article-title":"Taurine and atherosclerosis","author":"Murakami","year":"2012","journal-title":"Amino Acids"}],"container-title":["Diabetes &amp; Metabolic Syndrome: Clinical Research &amp; Reviews"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1871402114000502?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1871402114000502?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,4,5]],"date-time":"2022-04-05T16:46:33Z","timestamp":1649177193000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1871402114000502"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,1]]},"references-count":157,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2015,1]]}},"alternative-id":["S1871402114000502"],"URL":"https:\/\/doi.org\/10.1016\/j.dsx.2014.05.001","relation":{},"ISSN":["1871-4021"],"issn-type":[{"value":"1871-4021","type":"print"}],"subject":[],"published":{"date-parts":[[2015,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Protective and therapeutic effectiveness of taurine in diabetes mellitus: A rationale for antioxidant supplementation","name":"articletitle","label":"Article Title"},{"value":"Diabetes & Metabolic Syndrome: Clinical Research & Reviews","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.dsx.2014.05.001","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 Diabetes India. Published by Diabetes India All rights reserved.","name":"copyright","label":"Copyright"}]}}