{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T15:47:17Z","timestamp":1762876037149,"version":"build-2065373602"},"reference-count":18,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T00:00:00Z","timestamp":1546300800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T00:00:00Z","timestamp":1546300800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"name":"od MIUR (Ministery of University and Research, Italy"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Diabetes & Metabolic Syndrome: Clinical Research & Reviews"],"published-print":{"date-parts":[[2019,1]]},"DOI":"10.1016\/j.dsx.2018.11.042","type":"journal-article","created":{"date-parts":[[2018,11,16]],"date-time":"2018-11-16T12:10:40Z","timestamp":1542370240000},"page":"682-686","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":32,"title":["Why are so huge differences reported in the occurrence rate of skin lipohypertrophy? Does it depend on method defects or on lack of interest?"],"prefix":"10.1016","volume":"13","author":[{"given":"S.","family":"Gentile","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"Strollo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Guarino","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Brancario","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Corigliano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Cozzolino","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.R.","family":"Improta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Fasolino","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Lamberti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Lapice","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Martino","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Oliva","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Raffaele","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Selleri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Simonetti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Stile","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Vecchiato","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Vetrano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Volpe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Caputo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Del Sorbo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.G.","family":"Di Capua","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Durazzo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Egidio","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Garofalo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"Grasso","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Meo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Murano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"Perillo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Procida","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"Vietsi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"9","key":"10.1016\/j.dsx.2018.11.042_bib1","doi-asserted-by":"crossref","first-page":"1231","DOI":"10.1016\/j.mayocp.2016.06.010","article-title":"New insulin delivery recommendations","volume":"91","author":"Frid","year":"2016","journal-title":"Mayo Clin Proc"},{"issue":"24","key":"10.1016\/j.dsx.2018.11.042_bib2","first-page":"3","article-title":"AMD-OSDI consensus on injection techniques for people with diabetes mellitus","volume":"2","author":"Gentile","year":"2016","journal-title":"Med Clin Rev"},{"issue":"3","key":"10.1016\/j.dsx.2018.11.042_bib3","doi-asserted-by":"crossref","first-page":"750","DOI":"10.1177\/193229681000400332","article-title":"Insulin absorption from lipodystrophic areas: a (neglected) source of trouble for insulin therapy?","volume":"4","author":"Heinemann","year":"2010","journal-title":"J\u00a0Diabetes Sci Technol"},{"issue":"5","key":"10.1016\/j.dsx.2018.11.042_bib4","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1016\/j.diabet.2013.05.006","article-title":"Prevalence and risk factors of lipohypertrophy in insulin-injecting patients with diabetes","volume":"39","author":"Blanco","year":"2013","journal-title":"Diabetes Metab"},{"issue":"4","key":"10.1016\/j.dsx.2018.11.042_bib5","doi-asserted-by":"crossref","first-page":"444","DOI":"10.4239\/wjd.v5.i4.444","article-title":"Type 2 diabetes and cardiovascular disease: have all risk factors the same strength?","volume":"5","author":"Mart\u00edn-Tim\u00f3n","year":"2014","journal-title":"World J Diabetes"},{"key":"10.1016\/j.dsx.2018.11.042_bib6","first-page":"159","article-title":"Systematic inspection of insulin injection sites for local complications related to incorrect injection technique","volume":"26","author":"Seyoum","year":"1996","journal-title":"Trop Dr"},{"issue":"3","key":"10.1016\/j.dsx.2018.11.042_bib7","first-page":"28","article-title":"Lipohypertrophy: patient awareness and implications for practice","volume":"7","author":"Teft","year":"2002","journal-title":"J\u00a0Diabetes Nurs"},{"issue":"1","key":"10.1016\/j.dsx.2018.11.042_bib8","doi-asserted-by":"crossref","first-page":"24","DOI":"10.17140\/DROJ-2-126","article-title":"On behalf of AMD-OSDI Italian Study Group on Injection Techniques. Unexplained hypoglycaemia and large glycaemic variability: skin lipohypertrophy as a predictive sign","volume":"2","author":"Strollo","year":"2016","journal-title":"Diabetes Res Open J"},{"key":"10.1016\/j.dsx.2018.11.042_bib9","article-title":"Prevalence of lipohypertrophy in insulin-treated diabetes patients: a systematic review and meta-analysis","author":"Deng","year":"2017","journal-title":"J\u00a0Diabetes Investig"},{"issue":"Suppl 1","key":"10.1016\/j.dsx.2018.11.042_bib10","doi-asserted-by":"crossref","first-page":"S53","DOI":"10.1016\/j.dsx.2016.09.010","article-title":"Assessment of insulin injection techniques among diabetes patients in a tertiary care centre","volume":"11","author":"Patil","year":"2017","journal-title":"Diabetes Metab Syndr"},{"key":"10.1016\/j.dsx.2018.11.042_bib11","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1186\/s40064-016-1978-y","article-title":"A\u00a0suitable palpation technique allows to identify skin lipohypertrophic lesions in insulin-treated people with diabetes","volume":"5","author":"Gentile","year":"2016","journal-title":"SpringerPlus"},{"issue":"2","key":"10.1016\/j.dsx.2018.11.042_bib12","first-page":"00065","article-title":"Factors hindering correct identification of unapparent lipohypertrophy","volume":"3","author":"Gentile","year":"2016","journal-title":"J\u00a0Diabetes Metab Disord Control"},{"issue":"3","key":"10.1016\/j.dsx.2018.11.042_bib13","first-page":"00067","article-title":"Insulin shot dependent lipodystrophy: evidence, uncertainties and current terminology overlaps","volume":"3","author":"Gentile","year":"2016","journal-title":"J\u00a0Diabetes Metab Disord Control"},{"issue":"July 4","key":"10.1016\/j.dsx.2018.11.042_bib14","first-page":"145","article-title":"Optimizing insulin injection technique and its effect on blood glucose control","volume":"1","author":"Grassi","year":"2014","journal-title":"J\u00a0Clin Transl. Endocrinol"},{"issue":"5","key":"10.1016\/j.dsx.2018.11.042_bib15","doi-asserted-by":"crossref","first-page":"813","DOI":"10.1016\/j.dsx.2018.04.023","article-title":"Insulin related lipodystrophic lesions and hypoglycemia: double standards?","volume":"12","author":"Gentile","year":"2018","journal-title":"Diabetes Metab Syndr"},{"issue":"2","key":"10.1016\/j.dsx.2018.11.042_bib16","doi-asserted-by":"crossref","DOI":"10.5812\/ijem.33997","article-title":"Lipodistrophy and Associated Risk Factors in Insulin-Treated People With Diabetes","volume":"14","author":"Gentile","year":"2016","journal-title":"Int J Endocrinol Metabol"},{"issue":"October 10","key":"10.1016\/j.dsx.2018.11.042_bib17","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1007\/s12325-013-0066-8","article-title":"Improvement of glycemic control by re-education in insulin injection technique in patients with diabetes mellitus","volume":"30","author":"Nakatani","year":"2013","journal-title":"Adv Ther"},{"key":"10.1016\/j.dsx.2018.11.042_bib18","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1016\/j.diabres.2018.07.030","article-title":"Cost saving effects of a short-term educational intervention entailing lower hypoglycaemic event rates in people with type 1 diabetes and lipo-hypertrophy","volume":"143","author":"Gentile","year":"2018","journal-title":"Diabetes Res Clin Pract"}],"container-title":["Diabetes & Metabolic Syndrome: Clinical Research & Reviews"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1871402118305162?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1871402118305162?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T09:04:15Z","timestamp":1761728655000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1871402118305162"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,1]]},"references-count":18,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2019,1]]}},"alternative-id":["S1871402118305162"],"URL":"https:\/\/doi.org\/10.1016\/j.dsx.2018.11.042","relation":{},"ISSN":["1871-4021"],"issn-type":[{"type":"print","value":"1871-4021"}],"subject":[],"published":{"date-parts":[[2019,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Why are so huge differences reported in the occurrence rate of skin lipohypertrophy? Does it depend on method defects or on lack of interest?","name":"articletitle","label":"Article Title"},{"value":"Diabetes & Metabolic Syndrome: Clinical Research & Reviews","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.dsx.2018.11.042","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Published by Elsevier Ltd on behalf of Diabetes India.","name":"copyright","label":"Copyright"}]}}