{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T06:50:52Z","timestamp":1793170252041,"version":"4.5.0"},"reference-count":39,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2020,11,1]],"date-time":"2020-11-01T00:00:00Z","timestamp":1604188800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,11,1]],"date-time":"2020-11-01T00:00:00Z","timestamp":1604188800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100009530","name":"Jawaharlal Institute Of Postgraduate Medical Education and Research","doi-asserted-by":"publisher","award":["JIP\/Res\/Intramural\/Phs-1\/2018-19\/98"],"award-info":[{"award-number":["JIP\/Res\/Intramural\/Phs-1\/2018-19\/98"]}],"id":[{"id":"10.13039\/501100009530","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100009530","name":"Jawaharlal Institute Of Postgraduate Medical Education and Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100009530","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Diabetes & Metabolic Syndrome: Clinical Research & Reviews"],"published-print":{"date-parts":[[2020,11]]},"DOI":"10.1016\/j.dsx.2020.10.018","type":"journal-article","created":{"date-parts":[[2020,10,21]],"date-time":"2020-10-21T02:19:05Z","timestamp":1603246745000},"page":"2043-2051","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":16,"title":["Impaired baroreflex sensitivity and cardiac autonomic functions are associated with cardiovascular disease risk factors among patients with metabolic syndrome in a tertiary care teaching hospital of South-India"],"prefix":"10.1016","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6903-7280","authenticated-orcid":false,"given":"Chiranjeevi Kumar","family":"Endukuru","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6593-5187","authenticated-orcid":false,"given":"Girwar Singh","family":"Gaur","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dhanalakshmi","family":"Yerrabelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jayaprakash","family":"Sahoo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Balasubramaniyan","family":"Vairappan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"4","key":"10.1016\/j.dsx.2020.10.018_bib1","first-page":"896","article-title":"Metabolic syndrome, a widespread threatening condition; risk factors, diagnostic criteria, therapeutic options, prevention, and controversies: an overview","volume":"118","author":"Amihaesei","year":"2014","journal-title":"Rev Med-Chir Soc Med Nat Iasi"},{"issue":"8","key":"10.1016\/j.dsx.2020.10.018_bib2","doi-asserted-by":"crossref","first-page":"784","DOI":"10.1002\/dmrr.2555","article-title":"Heart rate variability and metabolic syndrome: a systematic review of the literature","volume":"30","author":"Stuckey","year":"2014","journal-title":"Diabetes metabolism research and reviews"},{"issue":"3","key":"10.1016\/j.dsx.2020.10.018_bib3","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1161\/01.CIR.0000111245.75752.C6","article-title":"Definition of metabolic syndrome: report of the National Heart, Lung, and Blood Institute\/American Heart Association conference on scientific issues related to definition","volume":"109","author":"Grundy","year":"2004","journal-title":"Circulation"},{"issue":"3","key":"10.1016\/j.dsx.2020.10.018_bib4","doi-asserted-by":"crossref","first-page":"47","DOI":"10.14341\/2071-8713-4854","article-title":"The IDF consensus worldwide definition of the metabolic syndrome","volume":"2","author":"Alberti","year":"2005","journal-title":"Obes Metabol"},{"issue":"2","key":"10.1016\/j.dsx.2020.10.018_bib5","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1016\/j.diabres.2010.11.025","article-title":"Prevalence of metabolic syndrome, and risk factors in adult Malaysians: results of a nationwide survey","volume":"91","author":"Mohamud","year":"2011","journal-title":"Diabetes Res Clin Pract"},{"issue":"3","key":"10.1016\/j.dsx.2020.10.018_bib6","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0192372","article-title":"Prevalence of metabolic syndrome and its risk factors in Kerala, South India: analysis of a community based cross-sectional study","volume":"13","author":"Harikrishnan","year":"2018","journal-title":"PloS One"},{"issue":"1","key":"10.1016\/j.dsx.2020.10.018_bib7","doi-asserted-by":"crossref","first-page":"7","DOI":"10.7322\/jhgd.96757","article-title":"Heart rate variability in metabolic syndrome","volume":"25","author":"Raimundo","year":"2015","journal-title":"Journal of Human Growth and Development"},{"issue":"9592","key":"10.1016\/j.dsx.2020.10.018_bib8","doi-asserted-by":"crossref","first-page":"1089","DOI":"10.1016\/S0140-6736(07)61305-1","article-title":"The cardiovascular toll of stress","volume":"370","author":"Brotman","year":"2007","journal-title":"Lancet"},{"key":"10.1016\/j.dsx.2020.10.018_bib9","first-page":"7","article-title":"Heart rate variability as a predictor of sudden cardiac death","author":"Kudaiberdieva","year":"2007","journal-title":"Anatol J Cardiol"},{"issue":"2","key":"10.1016\/j.dsx.2020.10.018_bib10","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1111\/j.1542-474X.2008.00219.x","article-title":"Baroreflex sensitivity: measurement and clinical implications","volume":"13","author":"La Rovere","year":"2008","journal-title":"Ann Noninvasive Electrocardiol"},{"issue":"3","key":"10.1016\/j.dsx.2020.10.018_bib11","doi-asserted-by":"crossref","first-page":"329","DOI":"10.2174\/157339906777950589","article-title":"Baroreflex function: determinants in healthy subjects and disturbances in diabetes, obesity and metabolic syndrome","volume":"2","author":"Skrapari","year":"2006","journal-title":"Curr Diabetes Rev"},{"issue":"2","key":"10.1016\/j.dsx.2020.10.018_bib12","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1016\/j.ijcard.2009.09.543","article-title":"The relationship of autonomic imbalance, heart rate variability and cardiovascular disease risk factors","volume":"141","author":"Thayer","year":"2010","journal-title":"Int J Cardiol"},{"issue":"5","key":"10.1016\/j.dsx.2020.10.018_bib13","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1016\/S0895-7061(98)00035-1","article-title":"Heart rate variability and baroreflex sensitivity in hypertensive subjects with and without metabolic features of insulin resistance syndrome","volume":"11","author":"Pikkujamsa","year":"1998","journal-title":"Am J Hypertens"},{"key":"10.1016\/j.dsx.2020.10.018_bib14","first-page":"2020","article-title":"Risk factors associated with cardiac autonomic modulation in obese individuals","author":"Oliveira","year":"2020","journal-title":"Journal of Obesity"},{"issue":"16","key":"10.1016\/j.dsx.2020.10.018_bib15","doi-asserted-by":"crossref","first-page":"1640","DOI":"10.1161\/CIRCULATIONAHA.109.192644","volume":"120","author":"Alberti","year":"2009","journal-title":"Circulation"},{"key":"10.1016\/j.dsx.2020.10.018_bib16","series-title":"World Health Organization physical status: the use and interpretation of anthropometry","author":"World Health Organization","year":"1995"},{"issue":"6","key":"10.1016\/j.dsx.2020.10.018_bib17","doi-asserted-by":"crossref","first-page":"1430","DOI":"10.1016\/j.clnu.2004.09.012","article-title":"Bioelectrical impedance analysis\u2014part II: utilization in clinical practice","volume":"23","author":"Kyle","year":"2004","journal-title":"Clin Nutr"},{"issue":"3","key":"10.1016\/j.dsx.2020.10.018_bib18","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1016\/S0008-6363(98)00067-4","article-title":"Fifteen years\u2019 experience with finger arterial pressure monitoring: assessment of the technology","volume":"38","author":"Imholz","year":"1998","journal-title":"Cardiovasc Res"},{"issue":"5","key":"10.1016\/j.dsx.2020.10.018_bib19","doi-asserted-by":"crossref","first-page":"1043","DOI":"10.1161\/01.CIR.93.5.1043","article-title":"Heart rate variability: standards of measurement, physiological interpretation, and clinical use","volume":"93","author":"Electrophysiology","year":"1996","journal-title":"Circulation"},{"issue":"S2","key":"10.1016\/j.dsx.2020.10.018_bib20","article-title":"Heart rate and the rate-pressure product as determinants of cardiovascular risk in patients with hypertension","volume":"12","author":"White","year":"1999","journal-title":"Am J Hypertens"},{"issue":"5","key":"10.1016\/j.dsx.2020.10.018_bib21","doi-asserted-by":"crossref","first-page":"491","DOI":"10.2337\/diacare.8.5.491","article-title":"The value of cardiovascular autonomic function tests: 10 years\u2019 experience in diabetes","volume":"8","author":"Ewing","year":"1985","journal-title":"Diabetes Care"},{"key":"10.1016\/j.dsx.2020.10.018_bib22","series-title":"Tietz textbook of clinical chemistry and molecular diagnostics-e-book","author":"Burtis","year":"2012"},{"issue":"6","key":"10.1016\/j.dsx.2020.10.018_bib23","doi-asserted-by":"crossref","first-page":"1487","DOI":"10.2337\/diacare.27.6.1487","article-title":"Use and abuse of HOMA modeling","volume":"27","author":"Wallace","year":"2004","journal-title":"Diabetes Care"},{"issue":"10","key":"10.1016\/j.dsx.2020.10.018_bib24","doi-asserted-by":"crossref","first-page":"700","DOI":"10.3390\/medicina55100700","article-title":"Daily heart rate variability indices in subjects with and without metabolic syndrome before and after the elimination of the influence of day-time physical activity","volume":"55","author":"Slusniene","year":"2019","journal-title":"Medicina"},{"issue":"11","key":"10.1016\/j.dsx.2020.10.018_bib25","doi-asserted-by":"crossref","first-page":"S68","DOI":"10.1016\/j.hrthm.2009.07.017","article-title":"Heart rate, autonomic markers, and cardiac mortality","volume":"6","author":"Verrier","year":"2009","journal-title":"Heart Rhythm"},{"issue":"1","key":"10.1016\/j.dsx.2020.10.018_bib26","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1097\/01.hjh.0000198024.91976.c2","article-title":"Baroreceptor sensitivity is impaired in elderly subjects with metabolic syndrome and insulin resistance","volume":"24","author":"Lindgren","year":"2006","journal-title":"J\u00a0Hypertens"},{"issue":"6","key":"10.1016\/j.dsx.2020.10.018_bib27","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1007\/s11906-008-0083-1","article-title":"Mediators of sympathetic activation in metabolic syndrome obesity","volume":"10","author":"Straznicky","year":"2008","journal-title":"Curr Hypertens Rep"},{"issue":"4","key":"10.1016\/j.dsx.2020.10.018_bib28","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1038\/jhh.2010.55","article-title":"Body size at birth and cardiovascular response to and recovery from mental stress in children","volume":"25","author":"Feldt","year":"2011","journal-title":"J\u00a0Hum Hypertens"},{"issue":"2","key":"10.1016\/j.dsx.2020.10.018_bib29","doi-asserted-by":"crossref","first-page":"151","DOI":"10.4103\/ijmr.IJMR_1751_16","article-title":"Contribution of insulin resistance to decreased baroreceptor sensitivity & cardiometabolic risks in pre-obesity & obesity","volume":"148","author":"Indumathy","year":"2018","journal-title":"Indian J Med Res"},{"issue":"2","key":"10.1016\/j.dsx.2020.10.018_bib30","doi-asserted-by":"crossref","first-page":"89","DOI":"10.3109\/07435800.2015.1076454","article-title":"Attenuated baroreflex sensitivity in normotensive prediabetes and diabetes in Indian adults","volume":"41","author":"Keerthi","year":"2016","journal-title":"Endocr Res"},{"issue":"12","key":"10.1016\/j.dsx.2020.10.018_bib31","doi-asserted-by":"crossref","first-page":"2116","DOI":"10.2337\/diacare.21.12.2116","article-title":"Multiple metabolic syndromes are associated with lower heart rate variability: the Atherosclerosis Risk in Communities Study","volume":"21","author":"Liao","year":"1998","journal-title":"Diabetes Care"},{"issue":"1","key":"10.1016\/j.dsx.2020.10.018_bib32","doi-asserted-by":"crossref","first-page":"31","DOI":"10.4103\/2230-8210.77582","article-title":"Relation of anthropometric variables to coronary artery disease risk factors","volume":"15","author":"Patil","year":"2011","journal-title":"Indian journal of endocrinology and metabolism"},{"issue":"5","key":"10.1016\/j.dsx.2020.10.018_bib33","first-page":"2253","article-title":"Body fat and its relationship with clustering of cardiovascular risk factors","volume":"31","author":"Valentino","year":"2015","journal-title":"Nutr Hosp"},{"issue":"12","key":"10.1016\/j.dsx.2020.10.018_bib34","doi-asserted-by":"crossref","first-page":"1862","DOI":"10.2337\/diacare.23.12.1862","article-title":"Inverse relationship between blood glucose and autonomic function in healthy subjects","volume":"23","author":"Lefrandt","year":"2000","journal-title":"Diabetes Care"},{"issue":"1","key":"10.1016\/j.dsx.2020.10.018_bib35","first-page":"64","article-title":"AIP--atherogenic index of plasma as a significant predictor of cardiovascular risk: from research to practice","volume":"52","author":"Dobiasova","year":"2006","journal-title":"Vnitr Lek"},{"issue":"8","key":"10.1016\/j.dsx.2020.10.018_bib36","doi-asserted-by":"crossref","first-page":"1014","DOI":"10.1016\/j.metabol.2006.03.011","article-title":"High serum high-sensitivity C-reactive protein concentrations are associated with relative cardiac sympathetic overactivity during the early morning period in type 2 diabetic patients with metabolic syndrome","volume":"55","author":"Aso","year":"2006","journal-title":"Metabolism"},{"issue":"1","key":"10.1016\/j.dsx.2020.10.018_bib37","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1186\/s12933-017-0634-3","article-title":"Adiponectin, biomarkers of inflammation and changes in cardiac autonomic function: whitehall II study","volume":"16","author":"Hansen","year":"2017","journal-title":"Cardiovasc Diabetol"},{"issue":"2","key":"10.1016\/j.dsx.2020.10.018_bib38","doi-asserted-by":"crossref","first-page":"H630","DOI":"10.1152\/ajpheart.00642.2001","article-title":"Reduced cardiovagal baroreflex gain in visceral obesity: implications for the metabolic syndrome","volume":"282","author":"Beske","year":"2002","journal-title":"Am J Physiol Heart Circ Physiol"},{"issue":"2","key":"10.1016\/j.dsx.2020.10.018_bib39","doi-asserted-by":"crossref","DOI":"10.1097\/MD.0000000000002472","article-title":"The neural baroreflex pathway in subjects with metabolic syndrome: a sub-study of the Paris prospective study III","volume":"95","author":"Zanoli","year":"2016","journal-title":"Medicine"}],"container-title":["Diabetes & Metabolic Syndrome: Clinical Research & Reviews"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1871402120304069?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1871402120304069?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T09:19:43Z","timestamp":1761729583000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1871402120304069"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,11]]},"references-count":39,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2020,11]]}},"alternative-id":["S1871402120304069"],"URL":"https:\/\/doi.org\/10.1016\/j.dsx.2020.10.018","relation":{},"ISSN":["1871-4021"],"issn-type":[{"value":"1871-4021","type":"print"}],"subject":[],"published":{"date-parts":[[2020,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Impaired baroreflex sensitivity and cardiac autonomic functions are associated with cardiovascular disease risk factors among patients with metabolic syndrome in a tertiary care teaching hospital of South-India","name":"articletitle","label":"Article Title"},{"value":"Diabetes & Metabolic Syndrome: Clinical Research & Reviews","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.dsx.2020.10.018","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Published by Elsevier Ltd on behalf of Diabetes India.","name":"copyright","label":"Copyright"}]}}