{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,2]],"date-time":"2025-12-02T15:12:52Z","timestamp":1764688372481,"version":"build-2065373602"},"reference-count":32,"publisher":"Elsevier BV","issue":"1-2","license":[{"start":{"date-parts":[[2004,4,1]],"date-time":"2004-04-01T00:00:00Z","timestamp":1080777600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2004,4,1]],"date-time":"2004-04-01T00:00:00Z","timestamp":1080777600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100002338","name":"Ministry of Education of the People&apos;s Republic of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002338","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Early Human Development"],"published-print":{"date-parts":[[2004,4]]},"DOI":"10.1016\/j.earlhumdev.2004.02.003","type":"journal-article","created":{"date-parts":[[2004,4,28]],"date-time":"2004-04-28T08:30:48Z","timestamp":1083141048000},"page":"89-98","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":26,"title":["DNA damage in healthy term neonate"],"prefix":"10.1016","volume":"77","author":[{"given":"Jin","family":"Zhao","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiao-Ju","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juan-Wen","family":"Ma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rong-Liang","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.earlhumdev.2004.02.003_BIB1","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1079\/PNS19870009","article-title":"Free radical problems of the newborn","volume":"46","author":"Muller","year":"1987","journal-title":"Proc. Nutr. Soc."},{"key":"10.1016\/j.earlhumdev.2004.02.003_BIB2","series-title":"Antioxidants in therapy and preventive medicine","first-page":"449","article-title":"Antioxidant activity in fetal and neonatal lung","author":"McElory","year":"1990"},{"key":"10.1016\/j.earlhumdev.2004.02.003_BIB3","doi-asserted-by":"crossref","first-page":"1058","DOI":"10.1002\/anie.198610581","article-title":"Biochemistry of oxidative stress","volume":"25","author":"Sies","year":"1986","journal-title":"Angew. Chem. Int. Ed. Engl."},{"key":"10.1016\/j.earlhumdev.2004.02.003_BIB4","doi-asserted-by":"crossref","first-page":"F130","DOI":"10.1136\/fn.81.2.F130","article-title":"Erythrocyte glutathione S transferase as a marker of oxidative stress at birth","volume":"81","author":"Neefjes","year":"1999","journal-title":"Arch. Dis. Child. Fetal Neonatal. Ed."},{"key":"10.1016\/j.earlhumdev.2004.02.003_BIB5","doi-asserted-by":"crossref","first-page":"S75","DOI":"10.1016\/S0378-3782(01)00209-2","article-title":"Oxidative stress in neonate","volume":"65","author":"Roblers","year":"2001","journal-title":"Early Hum. Dev."},{"key":"10.1016\/j.earlhumdev.2004.02.003_BIB6","doi-asserted-by":"crossref","first-page":"9125","DOI":"10.1016\/S0009-3084(99)00101-2","article-title":"Antioxidative and prooxidative effects of coumarin derivation on free radical initiated and photosensitized peroxidation of human low-density lipoprotein","volume":"103","author":"Liu","year":"1999","journal-title":"Chem. Phys. Lipids"},{"key":"10.1016\/j.earlhumdev.2004.02.003_BIB7","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/0921-8777(94)00043-6","article-title":"The kinetics of repair of oxidative DNA damage (strand breaks and oxidized pyrimidines) in human cells","volume":"336","author":"Collins","year":"1995","journal-title":"Mutat. Res."},{"key":"10.1016\/j.earlhumdev.2004.02.003_BIB8","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/S1383-5718(97)00107-1","article-title":"Quercetin and myricetin protect against hydrogen peroxide-induced DNA damage {strand breaks and oxidized pyrimidines} in human lymphocytes","volume":"393","author":"Duthie","year":"1997","journal-title":"Mutat. Res."},{"key":"10.1016\/j.earlhumdev.2004.02.003_BIB9","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1016\/0014-4827(88)90265-0","article-title":"A simple technique for quantitation of low levels of damage in individual cells","volume":"175","author":"Singh","year":"1988","journal-title":"Exp. Cell Res."},{"key":"10.1016\/j.earlhumdev.2004.02.003_BIB10","first-page":"852","article-title":"Protection against damaged DNA in single cell by polyphenols","volume":"57","author":"Liu","year":"2002","journal-title":"Pharmazie"},{"key":"10.1016\/j.earlhumdev.2004.02.003_BIB11","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/S1383-5718(00)00041-3","article-title":"In vivo DNA damage in gastric epithelial cells","volume":"468","author":"Everett","year":"2000","journal-title":"Mutat. Res."},{"key":"10.1016\/j.earlhumdev.2004.02.003_BIB12","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1016\/0003-2697(76)90326-2","article-title":"A fluorometric method for determination of oxidized and reduced glutathione in tissues","volume":"74","author":"Hissin","year":"1976","journal-title":"Anal. Biochem."},{"key":"10.1016\/j.earlhumdev.2004.02.003_BIB13","first-page":"325","article-title":"Kinetic of lipid peroxidation in rat liver microsomes","volume":"37","author":"Zheng","year":"1992","journal-title":"Chin. Sci. Bull."},{"key":"10.1016\/j.earlhumdev.2004.02.003_BIB14","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1006\/abio.1996.0292","article-title":"The ferric reducing ability of plasma (FRAP) as a measure of \u201cantioxidant power\u201d: the FRAP assay","volume":"15","author":"Benzie","year":"1996","journal-title":"Anal. Biochem."},{"key":"10.1016\/j.earlhumdev.2004.02.003_BIB15","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1203\/00006450-199607000-00003","article-title":"Increased levels of lipid peroxidation products malondialdehyde and 4-hydroxynonenal after perinatal hypoxia","volume":"40","author":"Schmidt","year":"1996","journal-title":"Pediatr. Res."},{"key":"10.1016\/j.earlhumdev.2004.02.003_BIB16","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1203\/00006450-200007000-00015","article-title":"Protein carbonyls and lipid peroxidation products as oxidation markers in preterm infant plasma: associations with chronic lung disease and retinopathy and effects of selenium supplementation","volume":"48","author":"Winterbourn","year":"2000","journal-title":"Pediatr. Res."},{"key":"10.1016\/j.earlhumdev.2004.02.003_BIB17","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1080\/15216540050167034","article-title":"Age-related changes of liver antioxidant enzymes and 8-hydroxy-2\u2032-deoxyguanosine during fetal-neonate transition and early rat development","volume":"49","author":"Muniz","year":"2000","journal-title":"IUBMB Life"},{"key":"10.1016\/j.earlhumdev.2004.02.003_BIB18","first-page":"2219","article-title":"Gama-GCS and glutathione, new molecular targets in cancer treatment","volume":"24","author":"Kondo","year":"1997","journal-title":"Gan To Kagaku Ryoho (Japansdd)"},{"key":"10.1016\/j.earlhumdev.2004.02.003_BIB19","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/S0027-5107(97)00150-4","article-title":"Modulation of NF-Kappa B, and bcl-2 in apoptosis induced by cisplatin in HeLa cells","volume":"381","author":"Maldonado","year":"1997","journal-title":"Mutat. Res."},{"key":"10.1016\/j.earlhumdev.2004.02.003_BIB20","doi-asserted-by":"crossref","first-page":"F67","DOI":"10.1136\/fn.79.1.F67","article-title":"Breath pentane as a marker for lipid peroxidation and adverse outcome in preterm infants","volume":"79","author":"Nycyk","year":"1998","journal-title":"Arch. Dis. Child. Fetal Neonatal. Ed."},{"key":"10.1016\/j.earlhumdev.2004.02.003_BIB21","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1111\/j.1471-0528.1998.tb10204.x","article-title":"Lipid peroxidation in cord blood at birth: the effect of labour","volume":"105","author":"Roger","year":"1998","journal-title":"Br. J. Obstet. Gynaecol."},{"key":"10.1016\/j.earlhumdev.2004.02.003_BIB22","doi-asserted-by":"crossref","first-page":"766","DOI":"10.1016\/S0891-5849(98)00126-9","article-title":"Intraerythrocyte nonprotein-bound iron and plasma malondialdehyde in the hypoxic newborn","volume":"25","author":"Buonocore","year":"1998","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.earlhumdev.2004.02.003_BIB23","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1016\/S0006-8993(98)00408-9","article-title":"Direct measurement of oxygen free radicals during in utero hypoxia in the fetal guinea pig brain","volume":"798","author":"Maulik","year":"1998","journal-title":"Brain Res."},{"key":"10.1016\/j.earlhumdev.2004.02.003_BIB24","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1203\/00006450-200002000-00012","article-title":"Total hydroperoxide and advanced oxidation protein products in preterm hypoxic babies","volume":"47","author":"Buonocore","year":"2000","journal-title":"Pediatr. Res."},{"key":"10.1016\/j.earlhumdev.2004.02.003_BIB25","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1203\/00006450-199004000-00001","article-title":"Experimental biology of cerebral hypoxia-ischemia relation to perinatal brain damage","volume":"27","author":"Vannucci","year":"1990","journal-title":"Pediatr. Res."},{"key":"10.1016\/j.earlhumdev.2004.02.003_BIB26","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1515\/jpme.1982.10.6.266","article-title":"Plasma hypoxanthine levels in newborn infants: a specific indicator of hypoxia","volume":"10","author":"Saugstad","year":"1982","journal-title":"J. Perinat. Med."},{"key":"10.1016\/j.earlhumdev.2004.02.003_BIB27","doi-asserted-by":"crossref","first-page":"1177","DOI":"10.1016\/0006-2952(91)90251-Y","article-title":"Phenolic compounds and an analog as superoxide anion scavengers and antioxidants","volume":"42","author":"Zhou","year":"1991","journal-title":"Biochem. Pharmacol."},{"key":"10.1016\/j.earlhumdev.2004.02.003_BIB28","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/S0969-806X(01)00224-9","article-title":"Fast repair activities of quercetin and rutin toward dGMP hydroxyl radical adducts","volume":"63","author":"Zhao","year":"2002","journal-title":"Radiat. Phys. Chem."},{"key":"10.1016\/j.earlhumdev.2004.02.003_BIB29","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1248\/bpb.24.777","article-title":"Antioxidant activity of Fraxatin: in vivo and ex vivo parameters in normal situation versus induced stress","volume":"24","author":"Fernandez-Puntero","year":"2001","journal-title":"Biol. Pharm. Bull."},{"key":"10.1016\/j.earlhumdev.2004.02.003_BIB30","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1006\/abbi.2000.1973","article-title":"Effects of trans-resveratrol on copper-dependent hydroxyl-radical formation and DNA damage: evidence for hydroxyl-radical scavenging and a novel, glutathione-sparing mechanism of action","volume":"381","author":"Burkitt","year":"2000","journal-title":"Arch. Biochem. Biophys."},{"key":"10.1016\/j.earlhumdev.2004.02.003_BIB31","doi-asserted-by":"crossref","first-page":"612","DOI":"10.1203\/00006450-200205000-00012","article-title":"Milk from mothers of premature and full-term infants provides better antioxidant protection than does infant formula","volume":"51","author":"Friel","year":"2002","journal-title":"Pediatr. Res."},{"key":"10.1016\/j.earlhumdev.2004.02.003_BIB32","doi-asserted-by":"crossref","first-page":"900","DOI":"10.1093\/ajcn\/60.6.900","article-title":"Postnatal changes in plasma chain-breaking antioxidants in healthy preterm infants fed formula and\/or human milk","volume":"60","author":"Van Zoeren-Grobben","year":"1994","journal-title":"Am. J. Clin. Nutr."}],"container-title":["Early Human Development"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378378204000222?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378378204000222?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T01:55:11Z","timestamp":1759888511000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378378204000222"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,4]]},"references-count":32,"journal-issue":{"issue":"1-2","published-print":{"date-parts":[[2004,4]]}},"alternative-id":["S0378378204000222"],"URL":"https:\/\/doi.org\/10.1016\/j.earlhumdev.2004.02.003","relation":{},"ISSN":["0378-3782"],"issn-type":[{"type":"print","value":"0378-3782"}],"subject":[],"published":{"date-parts":[[2004,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"DNA damage in healthy term neonate","name":"articletitle","label":"Article Title"},{"value":"Early Human Development","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.earlhumdev.2004.02.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"converted-article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2004 Elsevier Ireland Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}