{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T19:59:59Z","timestamp":1787169599161,"version":"build-2736575974"},"reference-count":40,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2011,5,1]],"date-time":"2011-05-01T00:00:00Z","timestamp":1304208000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Early Human Development"],"published-print":{"date-parts":[[2011,5]]},"DOI":"10.1016\/j.earlhumdev.2011.01.043","type":"journal-article","created":{"date-parts":[[2011,2,19]],"date-time":"2011-02-19T04:39:58Z","timestamp":1298090398000},"page":"325-330","source":"Crossref","is-referenced-by-count":72,"title":["Early postnatal blood concentrations of inflammation-related proteins and microcephaly two years later in infants born before the 28th post-menstrual week"],"prefix":"10.1016","volume":"87","author":[{"given":"Alan","family":"Leviton","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karl C.K.","family":"Kuban","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth N.","family":"Allred","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raina N.","family":"Fichorova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T. Michael","family":"O'Shea","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nigel","family":"Paneth","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"Suppl 1","key":"10.1016\/j.earlhumdev.2011.01.043_bb0005","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1111\/j.1471-0528.2005.00576.x","article-title":"Lung and brain damage in preterm newborns, and their association with gestational age, prematurity subgroup, infection\/inflammation and long term outcome","volume":"112","author":"Dammann","year":"2005","journal-title":"BJOG"},{"key":"10.1016\/j.earlhumdev.2011.01.043_bb0010","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1177\/0883073810377017","article-title":"Early cranial ultrasound lesions predict head circumference at age 2years in extremely low gestational preterm infants","volume":"26","author":"Krishnamoorthy","year":"2011","journal-title":"J Child Neurol"},{"key":"10.1016\/j.earlhumdev.2011.01.043_bb0015","doi-asserted-by":"crossref","first-page":"e1534","DOI":"10.1542\/peds.2007-2671","article-title":"Head growth in preterm infants: correlation with magnetic resonance imaging and neurodevelopmental outcome","volume":"121","author":"Cheong","year":"2008","journal-title":"Pediatrics"},{"key":"10.1016\/j.earlhumdev.2011.01.043_bb0020","doi-asserted-by":"crossref","first-page":"1119","DOI":"10.1177\/0883073809338066","article-title":"Fetal inflammatory response and brain injury in the preterm newborn","volume":"24","author":"Malaeb","year":"2009","journal-title":"J Child Neurol"},{"key":"10.1016\/j.earlhumdev.2011.01.043_bb0025","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1016\/j.clp.2008.07.011","article-title":"Cytokines and perinatal brain damage","volume":"35","author":"Dammann","year":"2008","journal-title":"Clin Perinatol"},{"key":"10.1016\/j.earlhumdev.2011.01.043_bb0030","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1016\/j.earlhumdev.2009.08.060","article-title":"The ELGAN study of the brain and related disorders in extremely low gestational age newborns","volume":"85","author":"O'Shea","year":"2009","journal-title":"Early Hum Dev"},{"key":"10.1016\/j.earlhumdev.2011.01.043_bb0035","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/0378-3782(87)90099-5","article-title":"New birthweight and head circumference centiles for gestational ages 24 to 42weeks","volume":"15","author":"Yudkin","year":"1987","journal-title":"Early Hum Dev"},{"key":"10.1016\/j.earlhumdev.2011.01.043_bb0040","author":"CDC"},{"key":"10.1016\/j.earlhumdev.2011.01.043_bb0045","doi-asserted-by":"crossref","first-page":"138.e1","DOI":"10.1016\/j.ajog.2010.05.006","article-title":"Factors associated with small head circumference at birth among infants born before the 28th week","volume":"203","author":"McElrath","year":"2010","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.earlhumdev.2011.01.043_bb0050","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1016\/j.earlhumdev.2010.07.001","article-title":"Antenatal antecedents of a small head circumference at age 24-months post-term equivalent in a sample of infants born before the 28th post-menstrual week","volume":"86","author":"Leviton","year":"2010","journal-title":"Early Hum Dev"},{"key":"10.1016\/j.earlhumdev.2011.01.043_bb0055","doi-asserted-by":"crossref","first-page":"1201","DOI":"10.1007\/s00247-007-0605-z","article-title":"Observer variability assessing US scans of the preterm brain: the ELGAN study","volume":"37","author":"Kuban","year":"2007","journal-title":"Pediatr Radiol"},{"key":"10.1016\/j.earlhumdev.2011.01.043_bb0060","doi-asserted-by":"crossref","first-page":"e662","DOI":"10.1542\/peds.2008-0594","article-title":"Neonatal cranial ultrasound lesions and developmental delays at 2years of age among extremely low gestational age children","volume":"122","author":"O'Shea","year":"2008","journal-title":"Pediatrics"},{"key":"10.1016\/j.earlhumdev.2011.01.043_bb0065","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1177\/08830738050200101001","article-title":"Video and CD-ROM as a training tool for performing neurologic examinations of 1-year-old children in a multicenter epidemiologic study","volume":"20","author":"Kuban","year":"2005","journal-title":"J Child Neurol"},{"key":"10.1016\/j.earlhumdev.2011.01.043_bb0070","doi-asserted-by":"crossref","first-page":"466-72.e1","DOI":"10.1016\/j.jpeds.2008.04.013","article-title":"An algorithm for diagnosing and classifying cerebral palsy in young children","volume":"153","author":"Kuban","year":"2008","journal-title":"J Pediatr"},{"key":"10.1016\/j.earlhumdev.2011.01.043_bb0075","doi-asserted-by":"crossref","first-page":"974","DOI":"10.1093\/ptj\/80.10.974","article-title":"Validation of a model of gross motor function for children with cerebral palsy","volume":"80","author":"Palisano","year":"2000","journal-title":"Phys Ther"},{"key":"10.1016\/j.earlhumdev.2011.01.043_bb0080","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/j.cyto.2010.09.003","article-title":"Inflammation-related proteins in the blood of extremely low gestational age newborns. The contribution of inflammation to the appearance of developmental regulation","volume":"53","author":"Leviton","year":"2011","journal-title":"Cytokine"},{"key":"10.1016\/j.earlhumdev.2011.01.043_bb0085","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1203\/PDR.0b013e3181fed334","article-title":"The relationship between neonatal blood protein profiles and placenta histologic characteristics in ELGANs","volume":"69","author":"Hecht","year":"2011","journal-title":"Pediatr Res"},{"key":"10.1016\/j.earlhumdev.2011.01.043_bb0090","doi-asserted-by":"crossref","first-page":"5773","DOI":"10.1128\/IAI.00631-06","article-title":"Trichomonas vaginalis lipophosphoglycan triggers a selective upregulation of cytokines by human female reproductive tract epithelial cells","volume":"74","author":"Fichorova","year":"2006","journal-title":"Infect Immun"},{"key":"10.1016\/j.earlhumdev.2011.01.043_bb0095","doi-asserted-by":"crossref","first-page":"4741","DOI":"10.1021\/ac702628q","article-title":"Biological and technical variables affecting immunoassay recovery of cytokines from human serum and simulated vaginal fluid: a multicenter study","volume":"80","author":"Fichorova","year":"2008","journal-title":"Anal Chem"},{"key":"10.1016\/j.earlhumdev.2011.01.043_bb0100","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1097\/00001648-199001000-00010","article-title":"No adjustments are needed for multiple comparisons","volume":"1","author":"Rothman","year":"1990","journal-title":"Epidemiology"},{"key":"10.1016\/j.earlhumdev.2011.01.043_bb0105","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1542\/peds.2008-0025","article-title":"Longitudinal brain volume changes in preterm and term control subjects during late childhood and adolescence","volume":"123","author":"Ment","year":"2009","journal-title":"Pediatrics"},{"key":"10.1016\/j.earlhumdev.2011.01.043_bb0110","doi-asserted-by":"crossref","first-page":"1112","DOI":"10.1177\/0883073809337920","article-title":"Molecular mechanisms involved in injury to the preterm brain","volume":"24","author":"Kaindl","year":"2009","journal-title":"J Child Neurol"},{"key":"10.1016\/j.earlhumdev.2011.01.043_bb0115","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1097\/01.mop.0000193290.02270.30","article-title":"Perinatal infections, prematurity and brain injury","volume":"18","author":"Edwards","year":"2006","journal-title":"Curr Opin Pediatr"},{"key":"10.1016\/j.earlhumdev.2011.01.043_bb0120","doi-asserted-by":"crossref","first-page":"2357","DOI":"10.1001\/jama.292.19.2357","article-title":"Neurodevelopmental and growth impairment among extremely low-birth-weight infants with neonatal infection","volume":"292","author":"Stoll","year":"2004","journal-title":"JAMA"},{"key":"10.1016\/j.earlhumdev.2011.01.043_bb0125","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1016\/j.jpeds.2008.02.033","article-title":"Adverse neurodevelopment in preterm infants with postnatal sepsis or necrotizing enterocolitis is mediated by white matter abnormalities on magnetic resonance imaging at term","volume":"153","author":"Shah","year":"2008","journal-title":"J Pediatr"},{"key":"10.1016\/j.earlhumdev.2011.01.043_bb0130","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1542\/peds.2007-2184","article-title":"Recurrent postnatal infections are associated with progressive white matter injury in premature infants","volume":"122","author":"Glass","year":"2008","journal-title":"Pediatrics"},{"key":"10.1016\/j.earlhumdev.2011.01.043_bb0135","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1055\/s-2002-37089","article-title":"Adult stroke and perinatal brain damage: like grandparent, like grandchild?","volume":"33","author":"Leviton","year":"2002","journal-title":"Neuropediatrics"},{"key":"10.1016\/j.earlhumdev.2011.01.043_bb0140","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1586\/ern.09.151","article-title":"Clinical application of blood biomarkers in cerebrovascular disease","volume":"10","author":"El Husseini","year":"2010","journal-title":"Expert Rev Neurother"},{"key":"10.1016\/j.earlhumdev.2011.01.043_bb0145","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1111\/j.1651-2227.2007.00097.x","article-title":"Persistent neuro-inflammation in cerebral palsy: a therapeutic window of opportunity?","volume":"96","author":"Dammann","year":"2007","journal-title":"Acta Paediatr"},{"key":"10.1016\/j.earlhumdev.2011.01.043_bb0150","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/j.jneuroim.2010.05.010","article-title":"The role of monocyte chemoattractant protein MCP1\/CCL2 in neuroinflammatory diseases","volume":"224","author":"Conductier","year":"2010","journal-title":"J Neuroimmunol"},{"key":"10.1016\/j.earlhumdev.2011.01.043_bb0155","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1542\/peds.2007-3264","article-title":"Brain and ventricles in very low birth weight infants at term: a comparison among head circumference, ultrasound, and magnetic resonance imaging","volume":"123","author":"Maunu","year":"2009","journal-title":"Pediatrics"},{"key":"10.1016\/j.earlhumdev.2011.01.043_bb0160","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1016\/j.ajem.2007.10.031","article-title":"The cytokine storm and factors determining the sequence and severity of organ dysfunction in multiple organ dysfunction syndrome","volume":"26","author":"Wang","year":"2008","journal-title":"Am J Emerg Med"},{"key":"10.1016\/j.earlhumdev.2011.01.043_bb0165","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1016\/S0166-2236(00)01811-7","article-title":"Do white cells matter in white matter damage?","volume":"24","author":"Dammann","year":"2001","journal-title":"Trends Neurosci"},{"key":"10.1016\/j.earlhumdev.2011.01.043_bb0170","doi-asserted-by":"crossref","first-page":"1032","DOI":"10.1038\/nature03985","article-title":"A network-based analysis of systemic inflammation in humans","volume":"437","author":"Calvano","year":"2005","journal-title":"Nature"},{"key":"10.1016\/j.earlhumdev.2011.01.043_bb0175","doi-asserted-by":"crossref","first-page":"1194","DOI":"10.1038\/nm1110-1194","article-title":"Inside the microbial and immune labyrinth: Totally gutted","volume":"16","author":"Macdonald","year":"2010","journal-title":"Nat Med"},{"key":"10.1016\/j.earlhumdev.2011.01.043_bb0180","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1111\/j.1469-8749.1987.tb08829.x","article-title":"Single-cause attribution","volume":"29","author":"Leviton","year":"1987","journal-title":"Dev Med Child Neurol"},{"key":"10.1016\/j.earlhumdev.2011.01.043_bb0185","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1016\/j.jpeds.2010.05.042","article-title":"Neurodevelopment of Extremely Preterm Infants who had Necrotizing Enterocolitis with or without Late Bacteremia","volume":"157","author":"Martin","year":"2010","journal-title":"J Pediatr"},{"key":"10.1016\/j.earlhumdev.2011.01.043_bb0190","doi-asserted-by":"crossref","first-page":"796","DOI":"10.1111\/j.1469-8749.2003.tb00893.x","article-title":"Factors associated with microcephaly at school age in a very-low-birthweight population","volume":"45","author":"Chiriboga","year":"2003","journal-title":"Dev Med Child Neurol"},{"key":"10.1016\/j.earlhumdev.2011.01.043_bb0195","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1017\/S001216220000013X","article-title":"Severe bronchopulmonary dysplasia increases risk for later neurological and motor sequelae in preterm survivors","volume":"42","author":"Majnemer","year":"2000","journal-title":"Dev Med Child Neurol"},{"key":"10.1016\/j.earlhumdev.2011.01.043_bb0200","doi-asserted-by":"crossref","first-page":"1118","DOI":"10.1016\/j.neuropsychologia.2003.11.022","article-title":"Head size and intelligence, learning, nutritional status and brain development. Head, IQ, learning, nutrition and brain","volume":"42","author":"Ivanovic","year":"2004","journal-title":"Neuropsychologia"}],"container-title":["Early Human Development"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378378211000806?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378378211000806?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,6,16]],"date-time":"2020-06-16T14:34:41Z","timestamp":1592318081000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378378211000806"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,5]]},"references-count":40,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2011,5]]}},"alternative-id":["S0378378211000806"],"URL":"https:\/\/doi.org\/10.1016\/j.earlhumdev.2011.01.043","relation":{},"ISSN":["0378-3782"],"issn-type":[{"value":"0378-3782","type":"print"}],"subject":[],"published":{"date-parts":[[2011,5]]}}}