{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T20:53:55Z","timestamp":1789764835037,"version":"4.0.1"},"reference-count":24,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2012,1,1]],"date-time":"2012-01-01T00:00:00Z","timestamp":1325376000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Early Human Development"],"published-print":{"date-parts":[[2012,1]]},"DOI":"10.1016\/j.earlhumdev.2011.07.009","type":"journal-article","created":{"date-parts":[[2011,8,6]],"date-time":"2011-08-06T20:19:28Z","timestamp":1312661968000},"page":"61-64","source":"Crossref","is-referenced-by-count":17,"title":["Higher incidence of thyroid agenesis in Mexican newborns with congenital hypothyroidism associated with birth defects"],"prefix":"10.1016","volume":"88","author":[{"given":"Susana","family":"Monroy-Santoyo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabel","family":"Ibarra-Gonz\u00e1lez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cynthia","family":"Fern\u00e1ndez-Lainez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sydney","family":"Greenawalt-Rodr\u00edguez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jorge","family":"Chac\u00f3n-Rey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ra\u00fal","family":"Calzada-Le\u00f3n","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcela","family":"Vela-Amieva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.earlhumdev.2011.07.009_bb0005","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1001\/archpedi.156.4.315","article-title":"Genetic epidemiology and congenital malformations: from de chromosome to the crib","volume":"156","author":"Hobbs","year":"2002","journal-title":"Arch Pediatr Adolesc Med"},{"key":"10.1016\/j.earlhumdev.2011.07.009_bb0010","doi-asserted-by":"crossref","DOI":"10.1186\/1750-1172-5-17","article-title":"Congenital hypothyroidism","author":"Rastogi","year":"2010","journal-title":"Orphanet J Rare Dis"},{"key":"10.1016\/j.earlhumdev.2011.07.009_bb0015","first-page":"531","article-title":"Birth prevalence of primary congenital hypothyroidism by sex and ethnicity","volume":"64","author":"Lorey","year":"1992","journal-title":"Hum Biol"},{"key":"10.1016\/j.earlhumdev.2011.07.009_bb0020","doi-asserted-by":"crossref","first-page":"S64","DOI":"10.1542\/peds.2009-1975G","article-title":"Future research to identify causes of the increasing incidence rate of congenital hypothyroidism in the United States","volume":"125","author":"Shapira","year":"2010","journal-title":"Pediatrics"},{"key":"10.1016\/j.earlhumdev.2011.07.009_bb0025","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1159\/000297595","article-title":"Therapeutic approach of fetal thyroid disorders","volume":"74","author":"Polak","year":"2010","journal-title":"Horm Res Paediatr"},{"key":"10.1016\/j.earlhumdev.2011.07.009_bb0030","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1002\/(SICI)1096-8628(19970711)71:1<29::AID-AJMG5>3.0.CO;2-L","article-title":"Population study of congenital hypothyroidism and associated birth defects, Atlanta, 1979\u20131992","volume":"71","author":"Roberts","year":"1997","journal-title":"Am J Med Genet"},{"key":"10.1016\/j.earlhumdev.2011.07.009_bb0035","doi-asserted-by":"crossref","first-page":"608","DOI":"10.1136\/adc.61.6.608","article-title":"Congenital anomalies associated with hypothyroidism","volume":"61","author":"Bamforth","year":"1986","journal-title":"Arch Child Dis"},{"key":"10.1016\/j.earlhumdev.2011.07.009_bb0040","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1016\/S0140-6736(88)92987-X","article-title":"Congenital abnormalities and congenital hypothyroidism","volume":"332","author":"Lazarus","year":"1988","journal-title":"Lancet"},{"key":"10.1016\/j.earlhumdev.2011.07.009_bb0045","doi-asserted-by":"crossref","DOI":"10.1186\/1687-9856-2010-940980","article-title":"High prevalence of associated birth defects in congenital hypothyroidism","author":"Reddy","year":"2010","journal-title":"Int J Pediatr Endocrinol"},{"key":"10.1016\/j.earlhumdev.2011.07.009_bb0050","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/j.jpeds.2008.08.023","article-title":"Increased prevalence of renal and urinary tract anomalies in children with congenital hypothyroidism","volume":"154","author":"Kumar","year":"2009","journal-title":"J Pediatr"},{"key":"10.1016\/j.earlhumdev.2011.07.009_bb0055","doi-asserted-by":"crossref","first-page":"1403","DOI":"10.1590\/S0004-27302008000900003","article-title":"New aspects of genetics and molecular mechanisms on thyroid morphogenesis for the understanding of thyroid dysgenesia","volume":"52","author":"Ramos","year":"2008","journal-title":"Arq Bras Endocrinol Metabol"},{"key":"10.1016\/j.earlhumdev.2011.07.009_bb0060","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1159\/000284386","article-title":"Epidemiology of thyroid dysgenesis: the familial component","volume":"73","author":"Castanet","year":"2010","journal-title":"Horm Res Paediatr"},{"key":"10.1016\/j.earlhumdev.2011.07.009_bb0065","doi-asserted-by":"crossref","first-page":"s37","DOI":"10.1542\/peds.2009-1975D","article-title":"Trends in incidence rates of congenital hypothyroidism related to select demographic factors: data from the United States, California, Massachusetts, New York, and Texas","volume":"125","author":"Hinton","year":"2010","journal-title":"Pediatrics"},{"key":"10.1016\/j.earlhumdev.2011.07.009_bb0070","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1590\/S0036-36342004000200008","article-title":"Epidemiolog\u00eda del hipotiroidismo cong\u00e9nito en M\u00e9xico","volume":"46","author":"Vela-Amieva","year":"2004","journal-title":"Salud Publica Mex"},{"key":"10.1016\/j.earlhumdev.2011.07.009_bb0075","first-page":"557","article-title":"A population-based study on the frequency of additional congenital malformations in infants with congenital hypothyroidism: data from the Italian Registry for Congenital Hypothyroidism (1991\u20131998)","volume":"87","author":"Olivieri","year":"2002","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.earlhumdev.2011.07.009_bb0080","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1002\/ajmg.1320440114","article-title":"Congenital anomalies concomitant with persistent primary congenital hypothyroidism","volume":"44","author":"Siebner","year":"1992","journal-title":"Am J Med Genet"},{"key":"10.1016\/j.earlhumdev.2011.07.009_bb0085","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1089\/thy.2005.15.165","article-title":"High prevalence of extrathyroid malformations in a cohort of Brazilian patients with permanent primary congenital hypothyroidism","volume":"15","author":"Kreisner","year":"2005","journal-title":"Thyroid"},{"key":"10.1016\/j.earlhumdev.2011.07.009_bb0090","doi-asserted-by":"crossref","first-page":"2502","DOI":"10.1210\/jcem.84.7.5831","article-title":"A search for the possible molecular mechanisms of thyroid dysgenesis: sex ratios and associated malformations","volume":"84","author":"Devos","year":"1999","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.earlhumdev.2011.07.009_bb0095","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.mce.2009.12.008","article-title":"Morphogenesis of the thyroid gland","volume":"323","author":"Fagman","year":"2010","journal-title":"Mol Cell Endocrinol"},{"key":"10.1016\/j.earlhumdev.2011.07.009_bb0100","unstructured":"http:\/\/www.salud.gob.mx\/unidades\/cdi\/nom\/031ssa29.html."},{"key":"10.1016\/j.earlhumdev.2011.07.009_bb0105","first-page":"234","article-title":"Congenital cardiac malformations in congenital hypothyroid patients in Isfahan","volume":"11","author":"Sabri","year":"2006","journal-title":"JRMS"},{"key":"10.1016\/j.earlhumdev.2011.07.009_bb0110","first-page":"94","article-title":"A case of Hirschsprung disease does thyroid hormone have any effect?","volume":"51","author":"Eren","year":"2009","journal-title":"Turk J Pediatr"},{"key":"10.1016\/j.earlhumdev.2011.07.009_bb0115","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1038\/jp.2008.208","article-title":"Beckwith\u2013Wiedemann syndrome associated with congenital hypothyroidism in a preterm neonate: a case report and literature review","volume":"29","author":"Ramadan","year":"2009","journal-title":"J Perinatol"},{"key":"10.1016\/j.earlhumdev.2011.07.009_bb0120","doi-asserted-by":"crossref","first-page":"881","DOI":"10.1515\/JPEM.2009.22.10.881","article-title":"Congenital hypothyroidism associated with neonatal tooth, pierre robin syndrome and congenital heart defects","volume":"22","author":"Toromanovic","year":"2009","journal-title":"J Pediatr Endocrinol Metab"}],"container-title":["Early Human Development"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378378211002325?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378378211002325?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,11,30]],"date-time":"2018-11-30T22:50:03Z","timestamp":1543618203000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378378211002325"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,1]]},"references-count":24,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2012,1]]}},"alternative-id":["S0378378211002325"],"URL":"https:\/\/doi.org\/10.1016\/j.earlhumdev.2011.07.009","relation":{},"ISSN":["0378-3782"],"issn-type":[{"value":"0378-3782","type":"print"}],"subject":[],"published":{"date-parts":[[2012,1]]}}}