{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,14]],"date-time":"2026-04-14T01:17:16Z","timestamp":1776129436956,"version":"3.50.1"},"reference-count":11,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2012,4,1]],"date-time":"2012-04-01T00:00:00Z","timestamp":1333238400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Early Human Development"],"published-print":{"date-parts":[[2012,4]]},"DOI":"10.1016\/j.earlhumdev.2011.07.021","type":"journal-article","created":{"date-parts":[[2011,8,17]],"date-time":"2011-08-17T18:03:19Z","timestamp":1313604199000},"page":"195-196","source":"Crossref","is-referenced-by-count":6,"title":["The effects of ibuprofen on sepsis parameters in preterm neonates"],"prefix":"10.1016","volume":"88","author":[{"given":"Gamze","family":"Demirel","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Istemi Han","family":"Celik","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fuat Emre","family":"Canpolat","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Omer","family":"Erdeve","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Serife Suna","family":"Oguz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ugur","family":"Dilmen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.earlhumdev.2011.07.021_bb0005","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1016\/j.jpeds.2010.10.008","article-title":"Efficacy and safety of oral versus intravenous ibuprofen in very low birth weight preterm infants with patent ductus arteriosus","volume":"158","author":"Gokmen","year":"2011","journal-title":"J Pediatr"},{"key":"10.1016\/j.earlhumdev.2011.07.021_bb0010","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1097\/00024382-199802000-00003","article-title":"Histamine receptor antagonists, cyclooxygenase blockade, and tumor necrosis factor during septic insult","volume":"9","author":"Leeper-Woodford","year":"1998","journal-title":"Shock"},{"key":"10.1016\/j.earlhumdev.2011.07.021_bb0015","doi-asserted-by":"crossref","first-page":"912","DOI":"10.1056\/NEJM199703273361303","article-title":"The effects of ibuprofen on the physiology and survival of patients with sepsis: The Ibuprofen in Sepsis Study Group","volume":"336","author":"Bernard","year":"1997","journal-title":"N Engl J Med"},{"key":"10.1016\/j.earlhumdev.2011.07.021_bb0020","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1002\/jcla.20420","article-title":"What are the cut-off levels for IL-6 and CRP in neonatal sepsis?","volume":"24","author":"Celik","year":"2010","journal-title":"J Clin Lab Anal"},{"key":"10.1016\/j.earlhumdev.2011.07.021_bb0025","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1046\/j.1365-2567.1996.472535.x","article-title":"Oral aspirin and ibuprofen increase cytokine-induced synthesis of IL-1 beta and tumor necrosis factor-alpha ex vivo","volume":"87","author":"Endres","year":"1996","journal-title":"Immunology"},{"key":"10.1016\/j.earlhumdev.2011.07.021_bb0030","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1006\/jsre.1996.4982","article-title":"Differential effects of IL-1 beta and ibuprofen after endotoxic challenge in mice","volume":"67","author":"Mansilla-Rosello","year":"1997","journal-title":"J Surg Res"},{"key":"10.1016\/j.earlhumdev.2011.07.021_bb0035","first-page":"165","article-title":"Effect of dexamethasone and ibuprofen on LPS-induced gene expression of TNF-, IL-1\u03b2 and MIP-1 in rat lung","volume":"18","author":"Qui","year":"1997","journal-title":"Chung Kuo Yao Li Hsueh Pao"},{"key":"10.1016\/j.earlhumdev.2011.07.021_bb0040","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1016\/S0006-2952(98)00301-3","article-title":"Ibuprofen: new explanation for old phenomenon","volume":"57","author":"Stuhlmeier","year":"1999","journal-title":"Biochem Pharmacol"},{"key":"10.1016\/j.earlhumdev.2011.07.021_bb0045","first-page":"49","article-title":"Efficacy of tumor necrosis factor alpha and eicosanoid inhibitors in experimental models of neonatal sepsis","volume":"9","author":"Mancuso","year":"1994","journal-title":"FEMS Immunol Med Microbiol"},{"issue":"5","key":"10.1016\/j.earlhumdev.2011.07.021_bb0050","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1097\/00000658-198411000-00011","article-title":"Inhibition of prostaglandin synthesis restores normal hemodynamics in canine hyperdynamic sepsis","volume":"200","author":"Fink","year":"1984","journal-title":"Ann Surg"},{"issue":"3","key":"10.1016\/j.earlhumdev.2011.07.021_bb0055","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1016\/0022-4804(92)90047-4","article-title":"Ibuprofen intervention in canine septic shock: reduction of pathophysiology without decreased cytokines","volume":"53","author":"Coran","year":"1992","journal-title":"J Surg Res"}],"container-title":["Early Human Development"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378378211002441?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378378211002441?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,11,30]],"date-time":"2018-11-30T17:55:54Z","timestamp":1543600554000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378378211002441"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,4]]},"references-count":11,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2012,4]]}},"alternative-id":["S0378378211002441"],"URL":"https:\/\/doi.org\/10.1016\/j.earlhumdev.2011.07.021","relation":{},"ISSN":["0378-3782"],"issn-type":[{"value":"0378-3782","type":"print"}],"subject":[],"published":{"date-parts":[[2012,4]]}}}