{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,21]],"date-time":"2026-06-21T09:22:33Z","timestamp":1782033753246,"version":"3.54.5"},"reference-count":27,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,3,1]],"date-time":"2021-03-01T00:00:00Z","timestamp":1614556800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,3,1]],"date-time":"2021-03-01T00:00:00Z","timestamp":1614556800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,3,1]],"date-time":"2021-03-01T00:00:00Z","timestamp":1614556800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2021,3,1]],"date-time":"2021-03-01T00:00:00Z","timestamp":1614556800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2021,3,1]],"date-time":"2021-03-01T00:00:00Z","timestamp":1614556800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2021,3,1]],"date-time":"2021-03-01T00:00:00Z","timestamp":1614556800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,3,1]],"date-time":"2021-03-01T00:00:00Z","timestamp":1614556800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100009619","name":"Japan Agency for Medical Research and Development","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009619","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Early Human Development"],"published-print":{"date-parts":[[2021,3]]},"DOI":"10.1016\/j.earlhumdev.2021.105319","type":"journal-article","created":{"date-parts":[[2021,1,26]],"date-time":"2021-01-26T18:05:13Z","timestamp":1611684313000},"page":"105319","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"special_numbering":"C","title":["Auditory brainstem response in preterm infants with bilirubin encephalopathy"],"prefix":"10.1016","volume":"154","author":[{"given":"Akihisa","family":"Okumura","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yukihiro","family":"Kitai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroshi","family":"Arai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masahiro","family":"Hayakawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshihiro","family":"Maruo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takashi","family":"Kusaka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tetsuya","family":"Kunikata","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Satoko","family":"Kumada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ichiro","family":"Morioka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.earlhumdev.2021.105319_bb0005","doi-asserted-by":"crossref","unstructured":"J.B. Le Pichon, S.M. Riordan, J. Watchko, S.M. Shapiro. The neurological sequelae of neonatal hyperbilirubinemia: definitions, diagnosis and treatment of the kernicterus spectrum disorders (KSDs). Curr. Pediatr. Rev. 13 (2017) 199\u2013209. doi:https:\/\/doi.org\/10.2174\/1573396313666170815100214.","DOI":"10.2174\/1573396313666170815100214"},{"key":"10.1016\/j.earlhumdev.2021.105319_bb0010","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1016\/j.clp.2016.01.006","article-title":"Bilirubin-induced Audiologic injury in preterm infants","volume":"43","author":"Olds","year":"2016","journal-title":"Clin. Perinatol."},{"key":"10.1016\/j.earlhumdev.2021.105319_bb0015","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1016\/j.clp.2016.01.007","article-title":"Bilirubin-induced neurotoxicity in the preterm neonate","volume":"43","author":"Watchko","year":"2016","journal-title":"Clin. Perinatol."},{"key":"10.1016\/j.earlhumdev.2021.105319_bb0020","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1053\/j.semperi.2014.08.002","article-title":"The enigma of low bilirubin kernicterus in premature infants: why does it still occur, and is it preventable?","volume":"38","author":"Watchko","year":"2014","journal-title":"Semin. Perinatol."},{"key":"10.1016\/j.earlhumdev.2021.105319_bb0025","doi-asserted-by":"crossref","first-page":"e1052","DOI":"10.1542\/peds.2008-2791","article-title":"Kernicterus in preterm infants","volume":"123","author":"Okumura","year":"2009","journal-title":"Pediatrics."},{"key":"10.1016\/j.earlhumdev.2021.105319_bb0030","doi-asserted-by":"crossref","unstructured":"Y. Kitai, S. Hirai, N. Okuyama, et al. Diagnosis of bilirubin encephalopathy in preterm infants with dyskinetic cerebral palsy. Neonatology 117. (2020) 73\u201379. doi:https:\/\/doi.org\/10.1159\/000502777.","DOI":"10.1159\/000502777"},{"key":"10.1016\/j.earlhumdev.2021.105319_bb0035","doi-asserted-by":"crossref","first-page":"494","DOI":"10.1111\/ped.12651","article-title":"Current incidence of clinical kernicterus in preterm infants in Japan","volume":"57","author":"Morioka","year":"2015","journal-title":"Pediatr. Int."},{"key":"10.1016\/j.earlhumdev.2021.105319_bb0040","doi-asserted-by":"crossref","first-page":"730","DOI":"10.1016\/j.braindev.2020.06.010","article-title":"A nationwide survey of bilirubin encephalopathy in preterm infants in Japan","volume":"42","author":"Okumura","year":"2020","journal-title":"Brain and Development"},{"key":"10.1016\/j.earlhumdev.2021.105319_bb0045","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1097\/00005537-200202000-00015","article-title":"Neonatal hearing loss in the indigent","volume":"112","author":"Oghalai","year":"2002","journal-title":"Laryngoscope."},{"key":"10.1016\/j.earlhumdev.2021.105319_bb0050","doi-asserted-by":"crossref","first-page":"F462","DOI":"10.1136\/adc.2007.124214","article-title":"Hearing loss in children with very low birth weight: current review of epidemiology and pathophysiology","volume":"93","author":"Cristobal","year":"2008","journal-title":"Arch. Dis. Child. Fetal Neonatal Ed."},{"key":"10.1016\/j.earlhumdev.2021.105319_bb0055","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1203\/00006450-199311000-00014","article-title":"Reversible brainstem auditory evoked potential abnormalities in jaundiced Gunn rats given sulfonamide","volume":"34","author":"Shapiro","year":"1993","journal-title":"Pediatr. Res."},{"issue":"Suppl","key":"10.1016\/j.earlhumdev.2021.105319_bb0060","doi-asserted-by":"crossref","first-page":"S52","DOI":"10.1038\/sj.jp.7210635","article-title":"Bilirubin and the auditory system","volume":"21","author":"Shapiro","year":"2001","journal-title":"J. Perinatol."},{"key":"10.1016\/j.earlhumdev.2021.105319_bb0065","doi-asserted-by":"crossref","first-page":"664","DOI":"10.1542\/peds.107.4.664","article-title":"Bilirubin and serial auditory brainstem responses in premature infants","volume":"107","author":"Amin","year":"2001","journal-title":"Pediatrics."},{"key":"10.1016\/j.earlhumdev.2021.105319_bb0070","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1038\/bmt.2012.244","article-title":"Investigation of the freely available easy-to-use software \u2018EZR\u2019 for medical statistics","volume":"48","author":"Kanda","year":"2013","journal-title":"Bone Marrow Transplant."},{"key":"10.1016\/j.earlhumdev.2021.105319_bb0075","doi-asserted-by":"crossref","first-page":"651","DOI":"10.3109\/00016488309139458","article-title":"The Gunn rat: an experimental model for central deafness","volume":"95","author":"Uziel","year":"1983","journal-title":"Acta Otolaryngol."},{"key":"10.1016\/j.earlhumdev.2021.105319_bb0080","doi-asserted-by":"crossref","first-page":"2201","DOI":"10.1002\/jnr.23107","article-title":"Bilirubin induces auditory neuropathy in neonatal guinea pigs via auditory nerve fiber damage","volume":"90","author":"Ye","year":"2012","journal-title":"J. Neurosci. Res."},{"key":"10.1016\/j.earlhumdev.2021.105319_bb0085","doi-asserted-by":"crossref","first-page":"13","DOI":"10.7874\/jao.2016.20.1.13","article-title":"Auditory brainstem response improvements in Hyperbillirubinemic infants","volume":"20","author":"Abdollahi","year":"2016","journal-title":"J. Audiol. Otol."},{"key":"10.1016\/j.earlhumdev.2021.105319_bb0090","doi-asserted-by":"crossref","first-page":"104909","DOI":"10.1016\/j.earlhumdev.2019.104909","article-title":"The spectrum of bilirubin neurotoxicity in term and near-term babies with hyperbilirubinemia: does outcome improve with time?","volume":"140","author":"ElTatawy","year":"2020","journal-title":"Early Hum. Dev."},{"key":"10.1016\/j.earlhumdev.2021.105319_bb0095","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1007\/s00405-010-1363-3","article-title":"Reversible auditory brainstem responses screening failures in high risk neonates","volume":"268","author":"Psarommatis","year":"2011","journal-title":"Eur. Arch. Otorhinolaryngol."},{"key":"10.1016\/j.earlhumdev.2021.105319_bb0100","doi-asserted-by":"crossref","first-page":"7912127","DOI":"10.1155\/2017\/7912127","article-title":"Recovery of abnormal ABR in neonates and infants at risk of hearing loss","volume":"2017","author":"Psarommatis","year":"2017","journal-title":"Int. J. Otolaryngol."},{"key":"10.1016\/j.earlhumdev.2021.105319_bb0105","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/j.clp.2016.01.003","article-title":"Bilirubin binding capacity in the preterm neonate","volume":"43","author":"Amin","year":"2016","journal-title":"Clin. Perinatol."},{"key":"10.1016\/j.earlhumdev.2021.105319_bb0110","doi-asserted-by":"crossref","first-page":"e1330","DOI":"10.1542\/peds.2013-1764","article-title":"Serum bilirubin and bilirubin\/albumin ratio as predictors of bilirubin encephalopathy","volume":"134","author":"Iskander","year":"2014","journal-title":"Pediatrics."},{"key":"10.1016\/j.earlhumdev.2021.105319_bb0115","doi-asserted-by":"crossref","first-page":"87","DOI":"10.3233\/NPM-181744","article-title":"Universal newborn hearing screening using A-TEOAE and A-ABR: the experience of a large public hospital","volume":"11","author":"Cianfrone","year":"2018","journal-title":"J. Neonatal. Perinatal. Med."},{"key":"10.1016\/j.earlhumdev.2021.105319_bb0120","doi-asserted-by":"crossref","first-page":"e641","DOI":"10.1542\/peds.2014-3784","article-title":"Sensitivity of the automated auditory brainstem response in neonatal hearing screening","volume":"136","author":"Levit","year":"2015","journal-title":"Pediatrics."},{"key":"10.1016\/j.earlhumdev.2021.105319_bb0125","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1542\/peds.2004-1688","article-title":"A multicenter evaluation of how many infants with permanent haring loss pass a two-stage otoacoustic emissions\/automated auditory brainstem response newborn hearing screening protocol","volume":"116","author":"Johnson","year":"2005","journal-title":"Pediatrics."},{"key":"10.1016\/j.earlhumdev.2021.105319_bb0130","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1016\/j.clinph.2006.12.015","article-title":"Reliability of hearing screening in high-risk neonates: comparative study of otoacoustic emission, automated and conventional auditory brainstem response","volume":"118","author":"Suppiej","year":"2007","journal-title":"Clin. Neurophysiol."},{"key":"10.1016\/j.earlhumdev.2021.105319_bb0135","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1016\/j.siny.2014.12.008","article-title":"The clinical syndrome of bilirubin-induced neurologic dysfunction","volume":"20","author":"Bhutani","year":"2015","journal-title":"Semin. Fetal Neonatal Med."}],"container-title":["Early Human Development"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378378221000153?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378378221000153?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T02:03:51Z","timestamp":1759889031000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378378221000153"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,3]]},"references-count":27,"alternative-id":["S0378378221000153"],"URL":"https:\/\/doi.org\/10.1016\/j.earlhumdev.2021.105319","relation":{},"ISSN":["0378-3782"],"issn-type":[{"value":"0378-3782","type":"print"}],"subject":[],"published":{"date-parts":[[2021,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Auditory brainstem response in preterm infants with bilirubin encephalopathy","name":"articletitle","label":"Article Title"},{"value":"Early Human Development","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.earlhumdev.2021.105319","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"105319"}}