{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T06:52:10Z","timestamp":1791528730005,"version":"4.3.4"},"reference-count":25,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100007129","name":"Natural Science Foundation of Shandong Province","doi-asserted-by":"publisher","award":["ZR2024QH105"],"award-info":[{"award-number":["ZR2024QH105"]}],"id":[{"id":"10.13039\/501100007129","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Early Human Development"],"published-print":{"date-parts":[[2026,12]]},"DOI":"10.1016\/j.earlhumdev.2026.106633","type":"journal-article","created":{"date-parts":[[2026,8,10]],"date-time":"2026-08-10T06:12:16Z","timestamp":1786342336000},"page":"106633","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Development and external validation of a prediction model for poor prognosis before discharge in very preterm and\/or very low birth weight infants with early-onset sepsis"],"prefix":"10.1016","volume":"223","author":[{"given":"Xiaowei","family":"Sun","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rui","family":"Jing","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jialin","family":"Wen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenying","family":"Meng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qianqian","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yang","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"4","key":"10.1016\/j.earlhumdev.2026.106633_bb0005","doi-asserted-by":"crossref","DOI":"10.1542\/peds.2021-052456","article-title":"Early-onset sepsis among very preterm infants","volume":"148","author":"Flannery","year":"2021","journal-title":"Pediatrics"},{"issue":"6","key":"10.1016\/j.earlhumdev.2026.106633_bb0010","article-title":"Management of neonates born at \u226434 6\/7 weeks\u2019 gestation with suspected or proven early-onset bacterial sepsis","volume":"142","author":"Puopolo","year":"2018","journal-title":"Pediatrics"},{"issue":"3","key":"10.1016\/j.earlhumdev.2026.106633_bb0015","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1001\/jama.2021.23580","article-title":"Mortality, in-hospital morbidity, care practices, and 2-year outcomes for extremely preterm infants in the US, 2013-2018","volume":"327","author":"Bell","year":"2022","journal-title":"JAMA"},{"issue":"1","key":"10.1016\/j.earlhumdev.2026.106633_bb0020","doi-asserted-by":"crossref","DOI":"10.1542\/peds.2020-030007","article-title":"Severity of bronchopulmonary dysplasia among very preterm infants in the United States","volume":"148","author":"Jensen","year":"2021","journal-title":"Pediatrics"},{"issue":"10","key":"10.1016\/j.earlhumdev.2026.106633_bb0025","first-page":"931","article-title":"Expert consensus on diagnosis and management of neonatal bacteria sepsis (2024)","volume":"62","author":"Subspecialty Group of Neonatology TSOP, Editorial Board CJOP","year":"2024","journal-title":"Zhonghua Er Ke Za Zhi"},{"issue":"19","key":"10.1016\/j.earlhumdev.2026.106633_bb0030","doi-asserted-by":"crossref","DOI":"10.3390\/ijms26199660","article-title":"Necrotizing enterocolitis: what\u2019s new and what\u2019s next?","volume":"26","author":"Sha","year":"2025","journal-title":"Int. J. Mol. Sci."},{"issue":"1","key":"10.1016\/j.earlhumdev.2026.106633_bb0035","doi-asserted-by":"crossref","first-page":"17346","DOI":"10.1038\/s41598-025-02061-4","article-title":"Risk assessment and early prediction of intraventricular hemorrhage in extremely preterm infants","volume":"15","author":"Cai","year":"2025","journal-title":"Sci. Rep."},{"issue":"1","key":"10.1016\/j.earlhumdev.2026.106633_bb0040","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1186\/s12887-023-04361-y","article-title":"Impact of early-onset fetal growth restriction on the neurodevelopmental outcome of very preterm infants at 24 months: a retrospective cohort study","volume":"23","author":"Cortez Ferreira","year":"2023","journal-title":"BMC Pediatr."},{"issue":"11","key":"10.1016\/j.earlhumdev.2026.106633_bb0045","doi-asserted-by":"crossref","DOI":"10.1001\/jamanetworkopen.2022.43691","article-title":"Analysis of antibiotic exposure and early-onset neonatal sepsis in Europe, North America, and Australia","volume":"5","author":"Giannoni","year":"2022","journal-title":"JAMA Netw. Open"},{"issue":"9","key":"10.1016\/j.earlhumdev.2026.106633_bb0050","doi-asserted-by":"crossref","DOI":"10.3390\/tropicalmed9090199","article-title":"Diagnosis and management of neonatal bacterial sepsis: current challenges and future perspectives","volume":"9","author":"De Rose","year":"2024","journal-title":"Trop. Med. Infect. Dis."},{"issue":"4","key":"10.1016\/j.earlhumdev.2026.106633_bb0055","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1007\/s12519-024-00803-4","article-title":"Early diagnosis and management of neonatal sepsis: a perspective","volume":"20","author":"Du","year":"2024","journal-title":"World J. Pediatr."},{"issue":"12","key":"10.1016\/j.earlhumdev.2026.106633_bb0060","doi-asserted-by":"crossref","first-page":"5517","DOI":"10.1007\/s00431-024-05811-0","article-title":"Management of neonates at risk of early onset sepsis: a probability-based approach and recent literature appraisal: update of the Swiss national guideline of the Swiss Society of Neonatology and the Pediatric Infectious Disease Group Switzerland","volume":"183","author":"Stocker","year":"2024","journal-title":"Eur. J. Pediatr."},{"issue":"11","key":"10.1016\/j.earlhumdev.2026.106633_bb0065","doi-asserted-by":"crossref","first-page":"756","DOI":"10.1542\/neo.23-10-e756","article-title":"Neonatal early-onset sepsis","volume":"23","author":"Flannery","year":"2022","journal-title":"NeoReviews"},{"issue":"5","key":"10.1016\/j.earlhumdev.2026.106633_bb0070","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1001\/jamapediatrics.2021.6619","article-title":"Interventions to prevent bronchopulmonary dysplasia in preterm neonates: an umbrella review of systematic reviews and meta-analyses","volume":"176","author":"Abiramalatha","year":"2022","journal-title":"JAMA Pediatr."},{"issue":"1","key":"10.1016\/j.earlhumdev.2026.106633_bb0075","doi-asserted-by":"crossref","DOI":"10.1001\/jamanetworkopen.2024.52883","article-title":"Intraventricular hemorrhage and survival, multimorbidity, and neurodevelopment","volume":"8","author":"Rees","year":"2025","journal-title":"JAMA Netw. Open"},{"issue":"6","key":"10.1016\/j.earlhumdev.2026.106633_bb0080","doi-asserted-by":"crossref","DOI":"10.1542\/peds.2022-057442","article-title":"Preterm brain injury and neurodevelopmental outcomes: a meta-analysis","volume":"150","author":"Rees","year":"2022","journal-title":"Pediatrics"},{"key":"10.1016\/j.earlhumdev.2026.106633_bb0085","doi-asserted-by":"crossref","DOI":"10.1016\/j.jpeds.2023.113600","article-title":"The impact of intraventricular hemorrhage and periventricular leukomalacia on mortality and neurodevelopmental outcome in very preterm and very low birthweight infants: a prospective population-based cohort study","volume":"262","author":"Pascal","year":"2023","journal-title":"J. Pediatr."},{"issue":"8","key":"10.1016\/j.earlhumdev.2026.106633_bb0090","doi-asserted-by":"crossref","first-page":"3147","DOI":"10.1007\/s00431-024-05569-5","article-title":"Neurodevelopmental outcomes of preterm with necrotizing enterocolitis: a systematic review and meta-analysis","volume":"183","author":"Wang","year":"2024","journal-title":"Eur. J. Pediatr."},{"issue":"1","key":"10.1016\/j.earlhumdev.2026.106633_bb0095","doi-asserted-by":"crossref","first-page":"14837","DOI":"10.1038\/s41598-023-41776-0","article-title":"Evaluating of neonatal early onset sepsis through lactate and base excess monitoring","volume":"13","author":"Yilmaz","year":"2023","journal-title":"Sci. Rep."},{"issue":"11","key":"10.1016\/j.earlhumdev.2026.106633_bb0100","doi-asserted-by":"crossref","DOI":"10.3390\/children10111796","article-title":"Association between serum lactate and morbidity and mortality in neonates: a systematic review and meta-analysis","volume":"10","author":"Matsushita","year":"2023","journal-title":"Children"},{"issue":"7","key":"10.1016\/j.earlhumdev.2026.106633_bb0105","doi-asserted-by":"crossref","DOI":"10.1590\/1806-9282.20231561","article-title":"A practical predictive model to predict 30-day mortality in neonatal sepsis","volume":"70","author":"Qiao","year":"2024","journal-title":"Rev. Assoc. Med. Bras."},{"issue":"3","key":"10.1016\/j.earlhumdev.2026.106633_bb0110","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1007\/s12519-021-00505-1","article-title":"Prediction modelling in the early detection of neonatal sepsis","volume":"18","author":"Sahu","year":"2022","journal-title":"World J. Pediatr."},{"key":"10.1016\/j.earlhumdev.2026.106633_bb0115","article-title":"Developing clinical prediction models: a step-by-step guide","volume":"386","author":"Efthimiou","year":"2024","journal-title":"BMJ (Clin. Res. Ed.)"},{"key":"10.1016\/j.earlhumdev.2026.106633_bb0120","article-title":"Evaluation of clinical prediction models (part 2): how to undertake an external validation study","volume":"384","author":"Riley","year":"2024","journal-title":"BMJ (Clin. Res. Ed.)"},{"key":"10.1016\/j.earlhumdev.2026.106633_bb0125","article-title":"TRIPOD+AI statement: updated guidance for reporting clinical prediction models that use regression or machine learning methods","volume":"385","author":"Collins","year":"2024","journal-title":"BMJ (Clin. Res. Ed.)"}],"container-title":["Early Human Development"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378378226001593?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378378226001593?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T06:42:57Z","timestamp":1791528177000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378378226001593"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,12]]},"references-count":25,"alternative-id":["S0378378226001593"],"URL":"https:\/\/doi.org\/10.1016\/j.earlhumdev.2026.106633","relation":{},"ISSN":["0378-3782"],"issn-type":[{"value":"0378-3782","type":"print"}],"subject":[],"published":{"date-parts":[[2026,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Development and external validation of a prediction model for poor prognosis before discharge in very preterm and\/or very low birth weight infants with early-onset sepsis","name":"articletitle","label":"Article Title"},{"value":"Early Human Development","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.earlhumdev.2026.106633","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"106633"}}