{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,28]],"date-time":"2026-05-28T01:53:09Z","timestamp":1779933189839,"version":"3.53.1"},"reference-count":7,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,2,1]],"date-time":"2018-02-01T00:00:00Z","timestamp":1517443200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,2,1]],"date-time":"2018-02-01T00:00:00Z","timestamp":1517443200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2018,1,26]],"date-time":"2018-01-26T00:00:00Z","timestamp":1516924800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["thelancet.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["EBioMedicine"],"published-print":{"date-parts":[[2018,2]]},"DOI":"10.1016\/j.ebiom.2018.01.036","type":"journal-article","created":{"date-parts":[[2018,1,31]],"date-time":"2018-01-31T13:45:47Z","timestamp":1517406347000},"page":"5-6","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"special_numbering":"C","title":["Targetable Metabolic Vulnerability in Diffuse Large B-Cell Lymphoma"],"prefix":"10.1016","volume":"28","author":[{"given":"Jie","family":"Xiong","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei-Li","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ebiom.2018.01.036_bb0005","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1016\/j.ccr.2012.08.014","article-title":"Metabolic signatures uncover distinct targets in molecular subsets of diffuse large B cell lymphoma","volume":"22","author":"Caro","year":"2012","journal-title":"Cancer Cell"},{"key":"10.1016\/j.ebiom.2018.01.036_bb0010","doi-asserted-by":"crossref","first-page":"1834","DOI":"10.1182\/blood-2010-09-307454","article-title":"Efficacy of l-asparaginase with methotrexate and dexamethasone (AspaMetDex regimen) in patients with refractory or relapsing extranodal NK\/T-cell lymphoma, a phase 2 study","volume":"117","author":"Jaccard","year":"2011","journal-title":"Blood"},{"key":"10.1016\/j.ebiom.2018.01.036_bb0015","doi-asserted-by":"crossref","first-page":"1269","DOI":"10.1016\/j.cell.2012.04.026","article-title":"Tumor suppression in the absence of p53-mediated cell-cycle arrest, apoptosis, and senescence","volume":"149","author":"Li","year":"2012","journal-title":"Cell"},{"key":"10.1016\/j.ebiom.2018.01.036_bb0020","doi-asserted-by":"crossref","DOI":"10.1016\/j.ebiom.2018.01.014","article-title":"Metabolomic profiling reveals cellular reprogramming of B-Cell lymphoma by a lysine deacetylase inhibitor through the choline pathway","author":"Pera","year":"2018","journal-title":"EBioMedicine"},{"key":"10.1016\/j.ebiom.2018.01.036_bb0025","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1158\/1078-0432.CCR-15-0362","article-title":"Molecular pathways: IDH2 mutations-co-opting cellular metabolism for malignant transformation","volume":"22","author":"Stein","year":"2016","journal-title":"Clin. Cancer Res."},{"key":"10.1016\/j.ebiom.2018.01.036_bb0030","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1038\/nrc.2016.85","article-title":"Altered metabolite levels in cancer: implications for tumour biology and cancer therapy","volume":"16","author":"Sullivan","year":"2016","journal-title":"Nat. Rev. Cancer"},{"key":"10.1016\/j.ebiom.2018.01.036_bb0035","doi-asserted-by":"crossref","DOI":"10.1038\/bcj.2017.61","article-title":"MYC is a positive regulator of choline metabolism and impedes mitophagy-dependent necroptosis in diffuse large B-cell lymphoma","volume":"7","author":"Xiong","year":"2017","journal-title":"Blood Cancer J."}],"container-title":["EBioMedicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2352396418300409?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2352396418300409?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,6]],"date-time":"2025-11-06T18:46:50Z","timestamp":1762454810000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2352396418300409"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,2]]},"references-count":7,"alternative-id":["S2352396418300409"],"URL":"https:\/\/doi.org\/10.1016\/j.ebiom.2018.01.036","relation":{},"ISSN":["2352-3964"],"issn-type":[{"value":"2352-3964","type":"print"}],"subject":[],"published":{"date-parts":[[2018,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Targetable Metabolic Vulnerability in Diffuse Large B-Cell Lymphoma","name":"articletitle","label":"Article Title"},{"value":"EBioMedicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ebiom.2018.01.036","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"https:\/\/doi.org\/10.1016\/j.ebiom.2018.01.014","name":"associatedlink","label":"CrossRef DOI link to the associated document"},{"value":"simple-article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}]}}