{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T21:59:33Z","timestamp":1791583173819,"version":"4.3.4"},"reference-count":114,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2019,6,1]],"date-time":"2019-06-01T00:00:00Z","timestamp":1559347200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,6,1]],"date-time":"2019-06-01T00:00:00Z","timestamp":1559347200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2019,5,24]],"date-time":"2019-05-24T00:00:00Z","timestamp":1558656000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100012651","name":"College of Veterinary Medicine, University of Florida","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100012651","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000001","name":"National Science Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000001","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["thelancet.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["eBioMedicine"],"published-print":{"date-parts":[[2019,6]]},"DOI":"10.1016\/j.ebiom.2019.05.052","type":"journal-article","created":{"date-parts":[[2019,5,31]],"date-time":"2019-05-31T08:47:02Z","timestamp":1559292422000},"page":"639-655","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":41,"special_numbering":"C","title":["Composition of the gut microbiota transcends genetic determinants of malaria infection severity and influences pregnancy outcome"],"prefix":"10.1016","volume":"44","author":[{"given":"Catherine D.","family":"Morffy Smith","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Minghao","family":"Gong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alicer K.","family":"Andrew","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brittany N.","family":"Russ","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yong","family":"Ge","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mojgan","family":"Zadeh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caitlin A.","family":"Cooper","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mansour","family":"Mohamadzadeh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5031-3270","authenticated-orcid":false,"given":"Julie M.","family":"Moore","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"4","key":"10.1016\/j.ebiom.2019.05.052_bb0005","doi-asserted-by":"crossref","DOI":"10.1016\/S1473-3099(18)30066-5","article-title":"Burden, pathology, and costs of malaria in pregnancy: new developments for an old problem","volume":"18","author":"Rogerson","year":"2018","journal-title":"Lancet Infect Dis"},{"issue":"8","key":"10.1016\/j.ebiom.2019.05.052_bb0010","doi-asserted-by":"crossref","first-page":"e460","DOI":"10.1016\/S2214-109X(14)70256-6","article-title":"Estimated risk of placental infection and low birthweight attributable to Plasmodium falciparum malaria in Africa in 2010: a modelling study","volume":"2","author":"Walker","year":"2014","journal-title":"Lancet Glob Health"},{"issue":"3","key":"10.1016\/j.ebiom.2019.05.052_bb0015","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1111\/j.1365-2559.1993.tb00111.x","article-title":"Placental malaria. II. A semi-quantitative investigation of the pathological features","volume":"22","author":"Bulmer","year":"1993","journal-title":"Histopathology"},{"issue":"2","key":"10.1016\/j.ebiom.2019.05.052_bb0020","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0031090","article-title":"Maternal malaria induces a procoagulant and antifibrinolytic state that is embryotoxic but responsive to anticoagulant therapy","volume":"7","author":"Avery","year":"2012","journal-title":"PLoS One"},{"issue":"5267","key":"10.1016\/j.ebiom.2019.05.052_bb0025","doi-asserted-by":"crossref","first-page":"1502","DOI":"10.1126\/science.272.5267.1502","article-title":"Adherence of Plasmodium falciparum to chondroitin sulfate A in the human placenta","volume":"272","author":"Fried","year":"1996","journal-title":"Science"},{"issue":"7","key":"10.1016\/j.ebiom.2019.05.052_bb0030","doi-asserted-by":"crossref","first-page":"1165","DOI":"10.1086\/319288","article-title":"Variants of plasmodium falciparum erythrocyte membrane protein 1 expressed by different placental parasites are closely related and adhere to chondroitin sulfate A","volume":"183","author":"Khattab","year":"2001","journal-title":"J Infect Dis"},{"issue":"6","key":"10.1016\/j.ebiom.2019.05.052_bb0035","doi-asserted-by":"crossref","first-page":"2013","DOI":"10.1016\/S0002-9440(10)63761-3","article-title":"Plasmodium falciparum-infected erythrocytes adhere both in the intervillous space and on the villous surface of human placenta by binding to the low-sulfated chondroitin sulfate proteoglycan receptor","volume":"164","author":"Muthusamy","year":"2004","journal-title":"Am J Pathol"},{"issue":"9","key":"10.1016\/j.ebiom.2019.05.052_bb0040","doi-asserted-by":"crossref","first-page":"5198","DOI":"10.1073\/pnas.96.9.5198","article-title":"The adhesion of Plasmodium falciparum-infected erythrocytes to chondroitin sulfate A is mediated by P. falciparum erythrocyte membrane protein 1","volume":"96","author":"Reeder","year":"1999","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"1","key":"10.1016\/j.ebiom.2019.05.052_bb0045","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1046\/j.1365-2958.2003.03570.x","article-title":"Selective upregulation of a single distinctly structured var gene in chondroitin sulphate A-adhering Plasmodium falciparum involved in pregnancy-associated malaria","volume":"49","author":"Salanti","year":"2003","journal-title":"Mol Microbiol"},{"issue":"2","key":"10.1016\/j.ebiom.2019.05.052_bb0050","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1046\/j.0960-7692.2001.00545.x","article-title":"Impaired uteroplacental blood flow in pregnancies complicated by falciparum malaria","volume":"19","author":"Dorman","year":"2002","journal-title":"Ultrasound Obstet Gynecol"},{"issue":"2","key":"10.1016\/j.ebiom.2019.05.052_bb0055","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1003153","article-title":"Plasmodium falciparum malaria elicits inflammatory responses that dysregulate placental amino acid transport","volume":"9","author":"Boeuf","year":"2013","journal-title":"PLoS Pathog"},{"issue":"1","key":"10.1016\/j.ebiom.2019.05.052_bb0060","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12916-016-0759-3","article-title":"Inhibition of placental mTOR signaling provides a link between placental malaria and reduced birthweight","volume":"15","author":"Dimasuay","year":"2017","journal-title":"BMC Med"},{"issue":"10","key":"10.1016\/j.ebiom.2019.05.052_bb0065","doi-asserted-by":"crossref","first-page":"1663","DOI":"10.1093\/infdis\/jit803","article-title":"Insight into the pathogenesis of fetal growth restriction in placental malaria: decreased placental glucose transporter isoform 1 expression","volume":"209","author":"Chandrasiri","year":"2014","journal-title":"J Infect Dis"},{"issue":"4","key":"10.1016\/j.ebiom.2019.05.052_bb0070","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1093\/infdis\/jiq080","article-title":"Placental malaria-associated inflammation disturbs the insulin-like growth factor axis of fetal growth regulation","volume":"203","author":"Umbers","year":"2011","journal-title":"J Infect Dis"},{"issue":"11","key":"10.1016\/j.ebiom.2019.05.052_bb0075","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0187291","article-title":"Impaired placental autophagy in placental malaria","volume":"12","author":"Dimasuay","year":"2017","journal-title":"PLoS One"},{"issue":"6","key":"10.1016\/j.ebiom.2019.05.052_bb0080","doi-asserted-by":"crossref","first-page":"581","DOI":"10.4269\/ajtmh.1995.53.581","article-title":"Increase of birth weight following chloroquine chemoprophylaxis during the first pregnancy: results of a randomized trial in Cameroon","volume":"53","author":"Cot","year":"1995","journal-title":"Am J Trop Med Hyg"},{"issue":"6","key":"10.1016\/j.ebiom.2019.05.052_bb0085","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1016\/S0035-9203(01)90082-3","article-title":"Malaria in pregnancy as an indirect cause of infant mortality in sub-Saharan Africa","volume":"95","author":"Guyatt","year":"2001","journal-title":"Trans R Soc Trop Med Hyg"},{"issue":"5","key":"10.1016\/j.ebiom.2019.05.052_bb0090","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1093\/aje\/154.5.459","article-title":"Effects of malaria during pregnancy on infant mortality in an area of low malaria transmission","volume":"154","author":"Luxemburger","year":"2001","journal-title":"Am J Epidemiol"},{"issue":"1\u20132","key":"10.1016\/j.ebiom.2019.05.052_bb0095","doi-asserted-by":"crossref","first-page":"28","DOI":"10.4269\/ajtmh.2001.64.28","article-title":"The burden of malaria in pregnancy in malaria-endemic areas","volume":"64","author":"Steketee","year":"2001","journal-title":"Am J Trop Med Hyg"},{"issue":"1 Suppl","key":"10.1016\/j.ebiom.2019.05.052_bb0100","doi-asserted-by":"crossref","first-page":"33","DOI":"10.4269\/ajtmh.1996.55.33","article-title":"The effect of malaria and malaria prevention in pregnancy on offspring birthweight, prematurity, and intrauterine growth retardation in rural Malawi","volume":"55","author":"Steketee","year":"1996","journal-title":"Am J Trop Med Hyg"},{"issue":"2 Suppl","key":"10.1016\/j.ebiom.2019.05.052_bb0105","doi-asserted-by":"crossref","first-page":"35","DOI":"10.4269\/ajtmh.2004.71.35","article-title":"The contribution of malaria in pregnancy to perinatal mortality","volume":"71","author":"van Geertruyden","year":"2004","journal-title":"Am J Trop Med Hyg"},{"issue":"1\u20132","key":"10.1016\/j.ebiom.2019.05.052_bb0110","doi-asserted-by":"crossref","first-page":"57","DOI":"10.4269\/ajtmh.2001.64.57","article-title":"Gaps in the childhood malaria burden in Africa: cerebral malaria, neurological sequelae, anemia, respiratory distress, hypoglycemia, and complications of pregnancy","volume":"64","author":"Murphy","year":"2001","journal-title":"Am J Trop Med Hyg"},{"issue":"11","key":"10.1016\/j.ebiom.2019.05.052_bb0115","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0027516","article-title":"Infections in infants during the first 12 months of life: role of placental malaria and environmental factors","volume":"6","author":"Le Port","year":"2011","journal-title":"PLoS One"},{"issue":"1","key":"10.1016\/j.ebiom.2019.05.052_bb0120","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1038\/s41598-017-18574-6","article-title":"Increased susceptibility to plasmodium falciparum in infants is associated with low, not high, placental malaria parasitemia","volume":"8","author":"Tassi Yunga","year":"2018","journal-title":"Sci Rep"},{"issue":"12","key":"10.1016\/j.ebiom.2019.05.052_bb0125","doi-asserted-by":"crossref","first-page":"1967","DOI":"10.1093\/infdis\/jiy140","article-title":"Additional screening and treatment of malaria during pregnancy provides further protection against Malaria and nonmalarial fevers during the first year of life","volume":"217","author":"Natama","year":"2018","journal-title":"J Infect Dis"},{"issue":"3","key":"10.1016\/j.ebiom.2019.05.052_bb0130","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1111\/j.1550-7408.1990.tb01121.x","article-title":"Influence of pregnancy on the course of malaria in mice infected with Plasmodium berghei","volume":"37","author":"Hioki","year":"1990","journal-title":"J Protozool"},{"issue":"1","key":"10.1016\/j.ebiom.2019.05.052_bb0135","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1111\/j.1550-7408.1982.tb02883.x","article-title":"Effects of malaria (Plasmodium berghei) on the maternal-fetal relationship in mice","volume":"29","author":"Oduola","year":"1982","journal-title":"J Protozool"},{"issue":"5","key":"10.1016\/j.ebiom.2019.05.052_bb0140","doi-asserted-by":"crossref","first-page":"2839","DOI":"10.1128\/IAI.74.5.2839-2848.2006","article-title":"Murine malaria infection induces fetal loss associated with accumulation of Plasmodium chabaudi AS-infected erythrocytes in the placenta","volume":"74","author":"Poovassery","year":"2006","journal-title":"Infect Immun"},{"issue":"11","key":"10.1016\/j.ebiom.2019.05.052_bb0145","doi-asserted-by":"crossref","first-page":"4998","DOI":"10.1128\/IAI.00617-09","article-title":"Association of malaria-induced murine pregnancy failure with robust peripheral and placental cytokine responses","volume":"77","author":"Poovassery","year":"2009","journal-title":"Infect Immun"},{"issue":"8","key":"10.1016\/j.ebiom.2019.05.052_bb0150","doi-asserted-by":"crossref","first-page":"5342","DOI":"10.4049\/jimmunol.0901669","article-title":"Malaria-induced murine pregnancy failure: distinct roles for IFN-gamma and TNF","volume":"183","author":"Poovassery","year":"2009","journal-title":"J Immunol"},{"issue":"7","key":"10.1016\/j.ebiom.2019.05.052_bb0155","doi-asserted-by":"crossref","first-page":"738","DOI":"10.1016\/j.placenta.2015.04.007","article-title":"Differential roles of inflammation and apoptosis in initiation of mid-gestational abortion in malaria-infected C57BL\/6 and A\/J mice","volume":"36","author":"Sarr","year":"2015","journal-title":"Placenta"},{"issue":"2","key":"10.1016\/j.ebiom.2019.05.052_bb0160","doi-asserted-by":"crossref","first-page":"630","DOI":"10.1128\/iai.28.2.630-632.1980","article-title":"Depressed malarial immunity in pregnant mice","volume":"28","author":"van Zon","year":"1980","journal-title":"Infect Immun"},{"issue":"2","key":"10.1016\/j.ebiom.2019.05.052_bb0165","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/S1473-3099(07)70021-X","article-title":"Epidemiology and burden of malaria in pregnancy","volume":"7","author":"Desai","year":"2007","journal-title":"Lancet Infect Dis"},{"issue":"1","key":"10.1016\/j.ebiom.2019.05.052_bb0170","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pmed.1000221","article-title":"Quantifying the number of pregnancies at risk of malaria in 2007: a demographic study","volume":"7","author":"Dellicour","year":"2010","journal-title":"PLoS Med"},{"issue":"2","key":"10.1016\/j.ebiom.2019.05.052_bb0175","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1016\/0035-9203(83)90081-0","article-title":"Malaria infection of the placenta in the Gambia, West Africa; its incidence and relationship to stillbirth, birthweight and placental weight","volume":"77","author":"McGregor","year":"1983","journal-title":"Trans R Soc Trop Med Hyg"},{"issue":"5","key":"10.1016\/j.ebiom.2019.05.052_bb0180","doi-asserted-by":"crossref","first-page":"996","DOI":"10.4269\/ajtmh.2010.10-0249","article-title":"Longitudinal studies of plasmodium falciparum malaria in pregnant women living in a rural Cameroonian village with high perennial transmission","volume":"83","author":"Leke","year":"2010","journal-title":"Am J Trop Med Hyg"},{"issue":"1","key":"10.1016\/j.ebiom.2019.05.052_bb0185","doi-asserted-by":"crossref","first-page":"9","DOI":"10.2471\/BLT.06.033258","article-title":"Adverse birth outcomes in United Republic of Tanzania\u2014impact and prevention of maternal risk factors","volume":"85","author":"Watson-Jones","year":"2007","journal-title":"Bull World Health Organ"},{"key":"10.1016\/j.ebiom.2019.05.052_bb0190","doi-asserted-by":"crossref","first-page":"1520","DOI":"10.3389\/fmicb.2016.01520","article-title":"Functional characteristics of the gut microbiome in C57BL\/6 mice differentially susceptible to plasmodium yoelii","volume":"7","author":"Stough","year":"2016","journal-title":"Front Microbiol"},{"issue":"8","key":"10.1016\/j.ebiom.2019.05.052_bb0195","doi-asserted-by":"crossref","first-page":"2235","DOI":"10.1073\/pnas.1504887113","article-title":"Composition of the gut microbiota modulates the severity of malaria","volume":"113","author":"Villarino","year":"2016","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"3","key":"10.1016\/j.ebiom.2019.05.052_bb0200","first-page":"322","article-title":"Helicobacter infection significantly alters pregnancy success in laboratory mice","volume":"56","author":"Bracken","year":"2017","journal-title":"J Am Assoc Lab Anim Sci"},{"issue":"2","key":"10.1016\/j.ebiom.2019.05.052_bb0205","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/j.cell.2004.07.002","article-title":"Recognition of commensal microflora by toll-like receptors is required for intestinal homeostasis","volume":"118","author":"Rakoff-Nahoum","year":"2004","journal-title":"Cell"},{"issue":"3","key":"10.1016\/j.ebiom.2019.05.052_bb0210","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0017996","article-title":"Depletion of murine intestinal microbiota: effects on gut mucosa and epithelial gene expression","volume":"6","author":"Reikvam","year":"2011","journal-title":"PLoS One"},{"issue":"3","key":"10.1016\/j.ebiom.2019.05.052_bb0215","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1016\/j.immuni.2015.08.011","article-title":"BALB\/c and C57BL\/6 mice differ in polyreactive IgA abundance, which impacts the generation of antigen-specific IgA and microbiota diversity","volume":"43","author":"Fransen","year":"2015","journal-title":"Immunity"},{"issue":"1","key":"10.1016\/j.ebiom.2019.05.052_bb0220","doi-asserted-by":"crossref","first-page":"3801","DOI":"10.1038\/s41598-018-20742-1","article-title":"Cyclical Bias' in microbiome research revealed by a portable germ-free housing system using nested isolation","volume":"8","author":"Rodriguez-Palacios","year":"2018","journal-title":"Sci Rep"},{"issue":"6","key":"10.1016\/j.ebiom.2019.05.052_bb0225","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0100532","article-title":"Colonic immune suppression, barrier dysfunction, and dysbiosis by gastrointestinal bacillus anthracis infection","volume":"9","author":"Lightfoot","year":"2014","journal-title":"PLoS One"},{"issue":"11","key":"10.1016\/j.ebiom.2019.05.052_bb0230","doi-asserted-by":"crossref","first-page":"3970","DOI":"10.1172\/JCI95376","article-title":"Commensal Propionibacterium strain UF1 mitigates intestinal inflammation via Th17 cell regulation","volume":"127","author":"Colliou","year":"2017","journal-title":"J Clin Invest"},{"issue":"5","key":"10.1016\/j.ebiom.2019.05.052_bb0235","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1038\/nmeth.f.303","article-title":"QIIME allows analysis of high-throughput community sequencing data","volume":"7","author":"Caporaso","year":"2010","journal-title":"Nat Methods"},{"issue":"6","key":"10.1016\/j.ebiom.2019.05.052_bb0240","doi-asserted-by":"crossref","first-page":"R60","DOI":"10.1186\/gb-2011-12-6-r60","article-title":"Metagenomic biomarker discovery and explanation","volume":"12","author":"Segata","year":"2011","journal-title":"Genome Biol"},{"issue":"4","key":"10.1016\/j.ebiom.2019.05.052_bb0245","doi-asserted-by":"crossref","first-page":"29","DOI":"10.4049\/immunohorizons.1700002","article-title":"Oxidative stress: a potential therapeutic target in placental malaria","volume":"1","author":"Sarr","year":"2017","journal-title":"Immunohorizons"},{"issue":"4","key":"10.1016\/j.ebiom.2019.05.052_bb0250","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1111\/j.1365-3024.2012.01355.x","article-title":"Plasmodium chabaudi AS induces pregnancy loss in association with systemic pro-inflammatory immune responses in A\/J and C57BL\/6 mice","volume":"34","author":"Sarr","year":"2012","journal-title":"Parasite Immunol"},{"issue":"3","key":"10.1016\/j.ebiom.2019.05.052_bb0255","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1002\/cyto.a.20647","article-title":"Quantitative measurement of plasmodium-infected erythrocytes in murine models of malaria by flow cytometry using bidimensional assessment of SYTO-16 fluorescence","volume":"75","author":"Jimenez-Diaz","year":"2009","journal-title":"Cytometry A"},{"issue":"3","key":"10.1016\/j.ebiom.2019.05.052_bb0260","first-page":"8","article-title":"Evaluation of saphenous venipuncture and modified tail-clip blood collection in mice","volume":"47","author":"Abatan","year":"2008","journal-title":"J Am Assoc Lab Anim Sci"},{"issue":"4","key":"10.1016\/j.ebiom.2019.05.052_bb0265","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1258\/002367789780746024","article-title":"Identification of newborn rats by tattooing","volume":"23","author":"Iwaki","year":"1989","journal-title":"Lab Anim"},{"issue":"2","key":"10.1016\/j.ebiom.2019.05.052_bb0270","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1093\/ilar.47.2.103","article-title":"Embryonic and neonatal phenotyping of genetically engineered mice","volume":"47","author":"Kulandavelu","year":"2006","journal-title":"ILAR J"},{"issue":"1","key":"10.1016\/j.ebiom.2019.05.052_bb0275","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1258\/002367786781062016","article-title":"A better method for terminal bleeding of mice","volume":"20","author":"Adeghe","year":"1986","journal-title":"Lab Anim"},{"issue":"4","key":"10.1016\/j.ebiom.2019.05.052_bb0280","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1182\/blood-2017-01-764910","article-title":"Platelet amyloid precursor protein is a modulator of venous thromboembolism in mice","volume":"130","author":"Canobbio","year":"2017","journal-title":"Blood"},{"issue":"6","key":"10.1016\/j.ebiom.2019.05.052_bb0285","doi-asserted-by":"crossref","first-page":"1101","DOI":"10.1038\/nprot.2008.73","article-title":"Analyzing real-time PCR data by the comparative C(T) method","volume":"3","author":"Schmittgen","year":"2008","journal-title":"Nat Protoc"},{"issue":"8","key":"10.1016\/j.ebiom.2019.05.052_bb0290","doi-asserted-by":"crossref","first-page":"1006","DOI":"10.1097\/00000478-199808000-00011","article-title":"Massive chronic intervillositis of the placenta associated with malaria infection","volume":"22","author":"Ordi","year":"1998","journal-title":"Am J Surg Pathol"},{"issue":"6","key":"10.1016\/j.ebiom.2019.05.052_bb0295","doi-asserted-by":"crossref","DOI":"10.1111\/pim.12433","article-title":"Neutrophil alterations in pregnancy-associated malaria and induction of neutrophil chemotaxis by Plasmodium falciparum","volume":"39","author":"Bostrom","year":"2017","journal-title":"Parasite Immunol"},{"key":"10.1016\/j.ebiom.2019.05.052_bb0300","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1016\/j.placenta.2017.03.001","article-title":"Uterine NK cells and macrophages in pregnancy","volume":"56","author":"Faas","year":"2017","journal-title":"Placenta"},{"issue":"5","key":"10.1016\/j.ebiom.2019.05.052_bb0305","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1016\/j.chom.2008.04.003","article-title":"Heme oxygenase-1 is an anti-inflammatory host factor that promotes murine plasmodium liver infection","volume":"3","author":"Epiphanio","year":"2008","journal-title":"Cell Host Microbe"},{"issue":"4","key":"10.1016\/j.ebiom.2019.05.052_bb0310","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1038\/sj.gene.6363841","article-title":"Complex genetic control of susceptibility to malaria in mice","volume":"3","author":"Fortin","year":"2002","journal-title":"Genes Immun"},{"issue":"7413","key":"10.1016\/j.ebiom.2019.05.052_bb0315","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1038\/nature11400","article-title":"Antibiotics in early life alter the murine colonic microbiome and adiposity","volume":"488","author":"Cho","year":"2012","journal-title":"Nature"},{"issue":"4","key":"10.1016\/j.ebiom.2019.05.052_bb0320","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1016\/j.cell.2014.05.052","article-title":"Altering the intestinal microbiota during a critical developmental window has lasting metabolic consequences","volume":"158","author":"Cox","year":"2014","journal-title":"Cell"},{"issue":"2","key":"10.1016\/j.ebiom.2019.05.052_bb0325","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0116704","article-title":"Effects of vendor and genetic background on the composition of the fecal microbiota of inbred mice","volume":"10","author":"Ericsson","year":"2015","journal-title":"PLoS One"},{"issue":"5","key":"10.1016\/j.ebiom.2019.05.052_bb0330","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1016\/j.ijmm.2016.03.004","article-title":"Analysis of factors contributing to variation in the C57BL\/6J fecal microbiota across German animal facilities","volume":"306","author":"Rausch","year":"2016","journal-title":"Int J Med Microbiol"},{"issue":"5","key":"10.1016\/j.ebiom.2019.05.052_bb0335","first-page":"336","article-title":"Variation in the gut microbiota of laboratory mice is related to both genetic and environmental factors","volume":"60","author":"Hufeldt","year":"2010","journal-title":"Comp Med"},{"issue":"2","key":"10.1016\/j.ebiom.2019.05.052_bb0340","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1016\/j.cell.2016.08.076","article-title":"Host-protozoan interactions protect from mucosal infections through activation of the inflammasome","volume":"167","author":"Chudnovskiy","year":"2016","journal-title":"Cell"},{"issue":"10","key":"10.1016\/j.ebiom.2019.05.052_bb0345","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0074957","article-title":"Bacterial community mapping of the mouse gastrointestinal tract","volume":"8","author":"Gu","year":"2013","journal-title":"PLoS One"},{"issue":"3","key":"10.1016\/j.ebiom.2019.05.052_bb0350","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1258\/la.2012.011128","article-title":"Faecal and caecal microbiota profiles of mice do not cluster in the same way","volume":"46","author":"Pang","year":"2012","journal-title":"Lab Anim"},{"issue":"1","key":"10.1016\/j.ebiom.2019.05.052_bb0355","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0170922","article-title":"Profiling living bacteria informs preparation of fecal microbiota transplantations","volume":"12","author":"Chu","year":"2017","journal-title":"PLoS One"},{"issue":"10","key":"10.1016\/j.ebiom.2019.05.052_bb0360","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0184336","article-title":"Gut microbiome of mothers delivering prematurely shows reduced diversity and lower relative abundance of Bifidobacterium and streptococcus","volume":"12","author":"Dahl","year":"2017","journal-title":"PLoS One"},{"issue":"7228","key":"10.1016\/j.ebiom.2019.05.052_bb0365","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1038\/nature07540","article-title":"A core gut microbiome in obese and lean twins","volume":"457","author":"Turnbaugh","year":"2009","journal-title":"Nature"},{"issue":"2","key":"10.1016\/j.ebiom.2019.05.052_bb0370","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1136\/gut.2005.073817","article-title":"Reduced diversity of faecal microbiota in Crohn's disease revealed by a metagenomic approach","volume":"55","author":"Manichanh","year":"2006","journal-title":"Gut"},{"issue":"7","key":"10.1016\/j.ebiom.2019.05.052_bb0375","doi-asserted-by":"crossref","first-page":"1099","DOI":"10.1038\/ijo.2017.66","article-title":"Gut microbiome diversity and high-fibre intake are related to lower long-term weight gain","volume":"41","author":"Menni","year":"2017","journal-title":"Int J Obes (Lond)"},{"issue":"10","key":"10.1016\/j.ebiom.2019.05.052_bb0380","doi-asserted-by":"crossref","first-page":"4726","DOI":"10.1128\/IAI.00319-08","article-title":"Antibiotic-induced perturbations of the intestinal microbiota alter host susceptibility to enteric infection","volume":"76","author":"Sekirov","year":"2008","journal-title":"Infect Immun"},{"issue":"1","key":"10.1016\/j.ebiom.2019.05.052_bb0385","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1016\/j.immuni.2012.04.011","article-title":"Commensal bacteria calibrate the activation threshold of innate antiviral immunity","volume":"37","author":"Abt","year":"2012","journal-title":"Immunity"},{"issue":"10","key":"10.1016\/j.ebiom.2019.05.052_bb0390","doi-asserted-by":"crossref","first-page":"2116","DOI":"10.1038\/ismej.2014.45","article-title":"Microbiome of prebiotic-treated mice reveals novel targets involved in host response during obesity","volume":"8","author":"Everard","year":"2014","journal-title":"ISME J"},{"issue":"1","key":"10.1016\/j.ebiom.2019.05.052_bb0395","doi-asserted-by":"crossref","first-page":"33","DOI":"10.3164\/jcbn.18-57","article-title":"A next-generation beneficial microbe: Akkermansia muciniphila","volume":"63","author":"Naito","year":"2018","journal-title":"J Clin Biochem Nutr"},{"issue":"22","key":"10.1016\/j.ebiom.2019.05.052_bb0400","doi-asserted-by":"crossref","first-page":"9066","DOI":"10.1073\/pnas.1219451110","article-title":"Cross-talk between Akkermansia muciniphila and intestinal epithelium controls diet-induced obesity","volume":"110","author":"Everard","year":"2013","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"7","key":"10.1016\/j.ebiom.2019.05.052_bb0405","doi-asserted-by":"crossref","first-page":"2365","DOI":"10.1073\/pnas.0812600106","article-title":"Human gut microbiota in obesity and after gastric bypass","volume":"106","author":"Zhang","year":"2009","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"1","key":"10.1016\/j.ebiom.2019.05.052_bb0410","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1017\/S0007114510000176","article-title":"Gut microbiota composition is associated with body weight, weight gain and biochemical parameters in pregnant women","volume":"104","author":"Santacruz","year":"2010","journal-title":"Br J Nutr"},{"issue":"2","key":"10.1016\/j.ebiom.2019.05.052_bb0415","doi-asserted-by":"crossref","first-page":"e450","DOI":"10.1038\/emm.2017.282","article-title":"Akkermansia muciniphila-derived extracellular vesicles influence gut permeability through the regulation of tight junctions","volume":"50","author":"Chelakkot","year":"2018","journal-title":"Exp Mol Med"},{"issue":"11","key":"10.1016\/j.ebiom.2019.05.052_bb0420","doi-asserted-by":"crossref","first-page":"3655","DOI":"10.1128\/AEM.04050-14","article-title":"Akkermansia muciniphila adheres to enterocytes and strengthens the integrity of the epithelial cell layer","volume":"81","author":"Reunanen","year":"2015","journal-title":"Appl Environ Microbiol"},{"issue":"6371","key":"10.1016\/j.ebiom.2019.05.052_bb0425","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1126\/science.aan3706","article-title":"Gut microbiome influences efficacy of PD-1-based immunotherapy against epithelial tumors","volume":"359","author":"Routy","year":"2018","journal-title":"Science"},{"issue":"8","key":"10.1016\/j.ebiom.2019.05.052_bb0430","doi-asserted-by":"crossref","first-page":"4399","DOI":"10.1128\/IAI.68.8.4399-4406.2000","article-title":"Central role of endogenous gamma interferon in protective immunity against blood-stage plasmodium chabaudi AS infection","volume":"68","author":"Su","year":"2000","journal-title":"Infect Immun"},{"key":"10.1016\/j.ebiom.2019.05.052_bb0435","doi-asserted-by":"crossref","first-page":"1208","DOI":"10.3389\/fmicb.2017.01208","article-title":"Preparing the gut with antibiotics enhances gut microbiota reprogramming efficiency by promoting xenomicrobiota colonization","volume":"8","author":"Ji","year":"2017","journal-title":"Front Microbiol"},{"key":"10.1016\/j.ebiom.2019.05.052_bb0440","doi-asserted-by":"crossref","DOI":"10.1038\/srep15699","article-title":"Plasmodium berghei ANKA causes intestinal malaria associated with dysbiosis","volume":"5","author":"Taniguchi","year":"2015","journal-title":"Sci Rep"},{"key":"10.1016\/j.ebiom.2019.05.052_bb0445","doi-asserted-by":"crossref","DOI":"10.1038\/srep14603","article-title":"Inflammation-associated alterations to the intestinal microbiota reduce colonization resistance against non-typhoidal Salmonella during concurrent malaria parasite infection","volume":"5","author":"Mooney","year":"2015","journal-title":"Sci Rep"},{"issue":"1","key":"10.1016\/j.ebiom.2019.05.052_bb0450","doi-asserted-by":"crossref","first-page":"3472","DOI":"10.1038\/s41598-019-40266-6","article-title":"Differential sensitivity to plasmodium yoelii infection in C57BL\/6 mice impacts gut-liver axis homeostasis","volume":"9","author":"Denny","year":"2019","journal-title":"Sci Rep"},{"issue":"6","key":"10.1016\/j.ebiom.2019.05.052_bb0455","doi-asserted-by":"crossref","first-page":"1277","DOI":"10.1016\/j.cell.2014.10.053","article-title":"Gut microbiota elicits a protective immune response against malaria transmission","volume":"159","author":"Yilmaz","year":"2014","journal-title":"Cell"},{"issue":"2","key":"10.1016\/j.ebiom.2019.05.052_bb0460","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1016\/j.chom.2018.07.002","article-title":"A gut commensal-produced metabolite mediates colonization resistance to salmonella infection","volume":"24","author":"Jacobson","year":"2018","journal-title":"Cell Host Microbe"},{"issue":"3","key":"10.1016\/j.ebiom.2019.05.052_bb0465","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0214449","article-title":"Intestinal short-chain fatty acid composition does not explain gut microbiota-mediated effects on malaria severity","volume":"14","author":"Chakravarty","year":"2019","journal-title":"PLoS One"},{"issue":"10","key":"10.1016\/j.ebiom.2019.05.052_bb0470","doi-asserted-by":"crossref","first-page":"1729","DOI":"10.1093\/cid\/cix623","article-title":"Systemic inflammatory response to Malaria during pregnancy is associated with pregnancy loss and preterm delivery","volume":"65","author":"Fried","year":"2017","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.ebiom.2019.05.052_bb0475","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1186\/1475-2875-7-26","article-title":"Maternal peripheral blood level of IL-10 as a marker for inflammatory placental malaria","volume":"7","author":"Kabyemela","year":"2008","journal-title":"Malar J"},{"issue":"1","key":"10.1016\/j.ebiom.2019.05.052_bb0480","doi-asserted-by":"crossref","first-page":"115","DOI":"10.4269\/ajtmh.2003.68.1.0680115","article-title":"Placental monocyte infiltrates in response to plasmodium falciparum malaria infection and their association with adverse pregnancy outcomes","volume":"68","author":"Rogerson","year":"2003","journal-title":"Am J Trop Med Hyg"},{"issue":"2","key":"10.1016\/j.ebiom.2019.05.052_bb0485","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0001608","article-title":"Pregnancy outcome and placenta pathology in plasmodium berghei ANKA infected mice reproduce the pathogenesis of severe malaria in pregnant women","volume":"3","author":"Neres","year":"2008","journal-title":"PLoS One"},{"issue":"2","key":"10.1016\/j.ebiom.2019.05.052_bb0490","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/j.chom.2013.01.010","article-title":"Complement activation and the resulting placental vascular insufficiency drives fetal growth restriction associated with placental malaria","volume":"13","author":"Conroy","year":"2013","journal-title":"Cell Host Microbe"},{"key":"10.1016\/j.ebiom.2019.05.052_bb0495","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1186\/s12864-015-1819-3","article-title":"Stool microbiota composition is associated with the prospective risk of plasmodium falciparum infection","volume":"16","author":"Yooseph","year":"2015","journal-title":"BMC Genomics"},{"issue":"9799","key":"10.1016\/j.ebiom.2019.05.052_bb0500","doi-asserted-by":"crossref","first-page":"1316","DOI":"10.1016\/S0140-6736(11)60888-X","article-title":"Relation between falciparum malaria and bacteraemia in Kenyan children: a population-based, case-control study and a longitudinal study","volume":"378","author":"Scott","year":"2011","journal-title":"Lancet"},{"issue":"5","key":"10.1016\/j.ebiom.2019.05.052_bb0505","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1004049","article-title":"Malaria parasite infection compromises control of concurrent systemic non-typhoidal salmonella infection via IL-10-mediated alteration of myeloid cell function","volume":"10","author":"Lokken","year":"2014","journal-title":"PLoS Pathog"},{"key":"10.1016\/j.ebiom.2019.05.052_bb0510","article-title":"Longitudinal analysis of infant stool bacteria communities before and after acute febrile malaria and artemether\/lumefantrine treatment","author":"Mandal","year":"2018","journal-title":"J Infect Dis"},{"issue":"2","key":"10.1016\/j.ebiom.2019.05.052_bb0515","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/0165-2478(88)90133-2","article-title":"Naturally-occurring anti-alpha-galactosyl antibodies in human Plasmodium falciparum infections\u2014a possible role for autoantibodies in malaria","volume":"19","author":"Ravindran","year":"1988","journal-title":"Immunol Lett"},{"issue":"3","key":"10.1016\/j.ebiom.2019.05.052_bb0520","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1016\/j.cell.2012.07.008","article-title":"Host remodeling of the gut microbiome and metabolic changes during pregnancy","volume":"150","author":"Koren","year":"2012","journal-title":"Cell"},{"key":"10.1016\/j.ebiom.2019.05.052_bb0525","doi-asserted-by":"crossref","first-page":"1835","DOI":"10.3389\/fmicb.2018.01835","article-title":"The human gut microbiome - a potential controller of wellness and disease","volume":"9","author":"Kho","year":"2018","journal-title":"Front Microbiol"},{"issue":"12","key":"10.1016\/j.ebiom.2019.05.052_bb0530","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1005997","article-title":"The impact of the gut microbiota on humoral immunity to pathogens and vaccination in early infancy","volume":"12","author":"Nguyen","year":"2016","journal-title":"PLoS Pathog"},{"issue":"3","key":"10.1016\/j.ebiom.2019.05.052_bb0535","doi-asserted-by":"crossref","DOI":"10.3390\/pathogens7030057","article-title":"The mammalian intestinal microbiome: composition, interaction with the immune system, significance for vaccine efficacy, and potential for disease therapy","volume":"7","author":"Desselberger","year":"2018","journal-title":"Pathogens"},{"issue":"1","key":"10.1016\/j.ebiom.2019.05.052_bb0540","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1021\/acsinfecdis.7b00232","article-title":"The human microbiota, infectious disease, and Global Health: challenges and opportunities","volume":"4","author":"Waldman","year":"2018","journal-title":"ACS Infect Dis"},{"issue":"5","key":"10.1016\/j.ebiom.2019.05.052_bb0545","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1056\/NEJMoa1205037","article-title":"Duodenal infusion of donor feces for recurrent Clostridium difficile","volume":"368","author":"van Nood","year":"2013","journal-title":"N Engl J Med"},{"issue":"6","key":"10.1016\/j.ebiom.2019.05.052_bb0550","first-page":"859","article-title":"Successful therapy of Clostridium difficile infection with fecal microbiota transplantation","volume":"67","author":"Konturek","year":"2016","journal-title":"J Physiol Pharmacol"},{"issue":"16","key":"10.1016\/j.ebiom.2019.05.052_bb0555","doi-asserted-by":"crossref","first-page":"2560","DOI":"10.1111\/febs.14107","article-title":"Vaccines against malaria-still a long way to go","volume":"284","author":"Matuschewski","year":"2017","journal-title":"FEBS J"},{"key":"10.1016\/j.ebiom.2019.05.052_bb0560","doi-asserted-by":"crossref","DOI":"10.1038\/srep23129","article-title":"Human gut colonisation may be initiated in utero by distinct microbial communities in the placenta and amniotic fluid","volume":"6","author":"Collado","year":"2016","journal-title":"Sci Rep"},{"issue":"1","key":"10.1016\/j.ebiom.2019.05.052_bb0565","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1016\/j.chom.2018.06.007","article-title":"Strain-level analysis of mother-to-child bacterial transmission during the first few months of life","volume":"24","author":"Yassour","year":"2018","journal-title":"Cell Host Microbe"},{"key":"10.1016\/j.ebiom.2019.05.052_bb0570","series-title":"World Malaria Report 2018","author":"WHO","year":"2018"}],"container-title":["eBioMedicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2352396419303603?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2352396419303603?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,3,18]],"date-time":"2025-03-18T18:02:32Z","timestamp":1742320952000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2352396419303603"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,6]]},"references-count":114,"alternative-id":["S2352396419303603"],"URL":"https:\/\/doi.org\/10.1016\/j.ebiom.2019.05.052","relation":{},"ISSN":["2352-3964"],"issn-type":[{"value":"2352-3964","type":"print"}],"subject":[],"published":{"date-parts":[[2019,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Composition of the gut microbiota transcends genetic determinants of malaria infection severity and influences pregnancy outcome","name":"articletitle","label":"Article Title"},{"value":"eBioMedicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ebiom.2019.05.052","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}]}}