{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T13:41:35Z","timestamp":1790602895852,"version":"4.1.0"},"reference-count":37,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2019,8,1]],"date-time":"2019-08-01T00:00:00Z","timestamp":1564617600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,8,1]],"date-time":"2019-08-01T00:00:00Z","timestamp":1564617600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2019,7,8]],"date-time":"2019-07-08T00:00:00Z","timestamp":1562544000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81571310"],"award-info":[{"award-number":["81571310"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81630033"],"award-info":[{"award-number":["81630033"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81771447"],"award-info":[{"award-number":["81771447"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000026","name":"National Institute on Drug Abuse","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000026","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000027","name":"National Institute on Alcohol Abuse and Alcoholism","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000027","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007123","name":"Stanley Medical Research Institute","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007123","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000344","name":"Shine","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000344","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["thelancet.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["eBioMedicine"],"published-print":{"date-parts":[[2019,8]]},"DOI":"10.1016\/j.ebiom.2019.07.022","type":"journal-article","created":{"date-parts":[[2019,7,12]],"date-time":"2019-07-12T07:58:44Z","timestamp":1562918324000},"page":"248-255","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":41,"special_numbering":"C","title":["Enhanced baseline activity in the left ventromedial putamen predicts individual treatment response in drug-naive, first-episode schizophrenia: Results from two independent study samples"],"prefix":"10.1016","volume":"46","author":[{"given":"Huabing","family":"Li","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1626-2465","authenticated-orcid":false,"given":"Wenbin","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Feng","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jindong","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qinji","family":"Su","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhikun","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoduo","family":"Fan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingping","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"4","key":"10.1016\/j.ebiom.2019.07.022_bb0005","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1016\/j.jchemneu.2003.10.003","article-title":"The primate basal ganglia: parallel and integrative networks","volume":"26","author":"Haber","year":"2003","journal-title":"J Chem Neuroanat"},{"issue":"5","key":"10.1016\/j.ebiom.2019.07.022_bb0010","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1016\/j.neuron.2010.02.014","article-title":"A possible role for the striatum in the pathogenesis of the cognitive symptoms of schizophrenia","volume":"65","author":"Simpson","year":"2010","journal-title":"Neuron"},{"issue":"1","key":"10.1016\/j.ebiom.2019.07.022_bb0015","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0030504","article-title":"Distribution of GABAergic interneurons and dopaminergic cells in the functional territories of the human striatum","volume":"7","author":"Bernacer","year":"2012","journal-title":"PLoS One"},{"issue":"9942","key":"10.1016\/j.ebiom.2019.07.022_bb0020","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1016\/S0140-6736(13)62418-6","article-title":"The expanding universe of disorders of the basal ganglia","volume":"384","author":"Obeso","year":"2014","journal-title":"Lancet"},{"key":"10.1016\/j.ebiom.2019.07.022_bb0025","doi-asserted-by":"crossref","first-page":"s13","DOI":"10.1192\/bjp.191.51.s13","article-title":"Molecular imaging studies of the striatal dopaminergic system in psychosis and predictions for the prodromal phase of psychosis","volume":"51","author":"Howes","year":"2007","journal-title":"Br J Psychiatry Suppl"},{"key":"10.1016\/j.ebiom.2019.07.022_bb0030","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1016\/j.ebiom.2018.10.009","article-title":"A schizophrenia-related genetic-brain-cognition pathway revealed in a large Chinese population","volume":"37","author":"Luo","year":"2018","journal-title":"EBioMedicine"},{"issue":"7","key":"10.1016\/j.ebiom.2019.07.022_bb0035","doi-asserted-by":"crossref","first-page":"1475","DOI":"10.1017\/S0033291711002157","article-title":"Volume increases in putamen associated with positive symptom reduction in previously drug-naive schizophrenia after 6 weeks antipsychotic treatment","volume":"42","author":"Li","year":"2012","journal-title":"Psychol Med"},{"issue":"9","key":"10.1016\/j.ebiom.2019.07.022_bb0040","doi-asserted-by":"crossref","first-page":"1099","DOI":"10.1016\/S0006-3223(99)00018-9","article-title":"MRI anatomy of schizophrenia","volume":"45","author":"McCarley","year":"1999","journal-title":"Biol Psychiatry"},{"issue":"2","key":"10.1016\/j.ebiom.2019.07.022_bb0045","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1097\/JCP.0b013e31820e3f58","article-title":"Brain volume changes after withdrawal of atypical antipsychotics in patients with first-episode schizophrenia","volume":"31","author":"Boonstra","year":"2011","journal-title":"J Clin Psychopharmacol"},{"issue":"3","key":"10.1016\/j.ebiom.2019.07.022_bb0050","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1016\/S0893-133X(99)00111-6","article-title":"Putamen mitochondrial energy metabolism is highly correlated to emotional and intellectual impairment in schizophrenics","volume":"22","author":"Prince","year":"2000","journal-title":"Neuropsychopharmacology"},{"issue":"1\u20133","key":"10.1016\/j.ebiom.2019.07.022_bb0055","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1016\/j.schres.2008.04.030","article-title":"Decrease in basal ganglia grey matter density associated with atypical antipsychotic treatment in schizophrenia patients","volume":"103","author":"Stip","year":"2008","journal-title":"Schizophr Res"},{"issue":"3","key":"10.1016\/j.ebiom.2019.07.022_bb0060","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/j.pscychresns.2006.10.002","article-title":"Basal ganglia volumes in drug-naive first-episode schizophrenia patients before and after short-term treatment with either a typical or an atypical antipsychotic drug","volume":"154","author":"Glenthoj","year":"2007","journal-title":"Psychiatry Res"},{"key":"10.1016\/j.ebiom.2019.07.022_bb0065","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1093\/schbul\/sbu126","article-title":"Abnormal causal connectivity by structural deficits in first-episode, drug-naive schizophrenia at rest","volume":"41","author":"Guo","year":"2015","journal-title":"Schizophr Bull"},{"issue":"10","key":"10.1016\/j.ebiom.2019.07.022_bb0070","doi-asserted-by":"crossref","first-page":"1785","DOI":"10.1176\/appi.ajp.162.10.1785","article-title":"Relationship between duration of untreated psychosis and outcome in first-episode schizophrenia: a critical review and meta-analysis","volume":"162","author":"Perkins","year":"2005","journal-title":"Am J Psychiatry"},{"issue":"9","key":"10.1016\/j.ebiom.2019.07.022_bb0075","doi-asserted-by":"crossref","first-page":"975","DOI":"10.1001\/archpsyc.62.9.975","article-title":"Association between duration of untreated psychosis and outcome in cohorts of first-episode patients: a systematic review","volume":"62","author":"Marshall","year":"2005","journal-title":"Arch Gen Psychiatry"},{"key":"10.1016\/j.ebiom.2019.07.022_bb0080","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/j.euroneuro.2016.11.002","article-title":"Olanzapine modulation of long- and short-range functional connectivity in the resting brain in a sample of patients with schizophrenia","volume":"27","author":"Guo","year":"2017","journal-title":"Eur Neuropsychopharmacol"},{"issue":"10","key":"10.1016\/j.ebiom.2019.07.022_bb0085","doi-asserted-by":"crossref","first-page":"1000","DOI":"10.1177\/0004867417714952","article-title":"Olanzapine modulates the default-mode network homogeneity in recurrent drug-free schizophrenia at rest","volume":"51","author":"Guo","year":"2017","journal-title":"Aust N Z J Psychiatry"},{"issue":"sup3","key":"10.1016\/j.ebiom.2019.07.022_bb0090","doi-asserted-by":"crossref","DOI":"10.1080\/15622975.2017.1346280","article-title":"Treatment effects of olanzapine on homotopic connectivity in drug-free schizophrenia at rest","volume":"19","author":"Guo","year":"2018","journal-title":"World J Biol Psychiatry"},{"issue":"7","key":"10.1016\/j.ebiom.2019.07.022_bb0095","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1016\/S0006-3223(02)01602-5","article-title":"Functional effects of antipsychotic drugs: comparing clozapine with haloperidol","volume":"53","author":"Lahti","year":"2003","journal-title":"Biol Psychiatry"},{"issue":"1","key":"10.1016\/j.ebiom.2019.07.022_bb0100","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0920-9964(02)00199-8","article-title":"Cerebral metabolism and risperidone treatment in schizophrenia","volume":"60","author":"Molina","year":"2003","journal-title":"Schizophr Res"},{"issue":"1","key":"10.1016\/j.ebiom.2019.07.022_bb0105","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1016\/j.pscychresns.2013.10.002","article-title":"Basal ganglia volume in unmedicated patients with schizophrenia is associated with treatment response to antipsychotic medication","volume":"221","author":"Hutcheson","year":"2014","journal-title":"Psychiatry Res"},{"issue":"8","key":"10.1016\/j.ebiom.2019.07.022_bb0110","doi-asserted-by":"crossref","first-page":"3508","DOI":"10.1093\/cercor\/bhw157","article-title":"The human brainnetome atlas: a new brain atlas based on connectional architecture","volume":"26","author":"Fan","year":"2016","journal-title":"Cereb Cortex"},{"issue":"2\u20133","key":"10.1016\/j.ebiom.2019.07.022_bb0115","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/j.schres.2009.06.022","article-title":"Poor outcome in chronic schizophrenia is associated with progressive loss of volume of the putamen","volume":"113","author":"Mitelman","year":"2009","journal-title":"Schizophr Res"},{"issue":"11","key":"10.1016\/j.ebiom.2019.07.022_bb0120","doi-asserted-by":"crossref","first-page":"1037","DOI":"10.1111\/cns.13048","article-title":"Machine learning in major depression: from classification to treatment outcome prediction","volume":"24","author":"Gao","year":"2018","journal-title":"CNS Neurosci Ther"},{"issue":"5","key":"10.1016\/j.ebiom.2019.07.022_bb0125","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1111\/acps.12945","article-title":"Complexity in mood disorder diagnosis: fMRI connectivity networks predicted medication-class of response in complex patients","volume":"138","author":"Osuch","year":"2018","journal-title":"Acta Psychiatr Scand"},{"key":"10.1016\/j.ebiom.2019.07.022_bb0130","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1016\/j.pnpbp.2017.08.012","article-title":"Abnormal long- and short-range functional connectivity in adolescent-onset schizophrenia patients: a resting-state fMRI study","volume":"81","author":"Wang","year":"2018","journal-title":"Prog Neuropsychopharmacol Biol Psychiatry"},{"key":"10.1016\/j.ebiom.2019.07.022_bb0135","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1016\/j.schres.2017.04.028","article-title":"Abnormal neural activity as a potential biomarker for drug-naive first-episode adolescent-onset schizophrenia with coherence regional homogeneity and support vector machine analyses","volume":"192","author":"Liu","year":"2018","journal-title":"Schizophr Res"},{"key":"10.1016\/j.ebiom.2019.07.022_bb0140","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/j.schres.2017.05.038","article-title":"Abnormal regional homogeneity as a potential imaging biomarker for adolescent-onset schizophrenia: a resting-state fMRI study and support vector machine analysis","volume":"192","author":"Wang","year":"2018","journal-title":"Schizophr Res"},{"issue":"6","key":"10.1016\/j.ebiom.2019.07.022_bb0145","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1001\/jamapsychiatry.2016.0316","article-title":"Prediction of individual response to electroconvulsive therapy via machine learning on structural magnetic resonance imaging data","volume":"73","author":"Redlich","year":"2016","journal-title":"JAMA Psychiat"},{"key":"10.1016\/j.ebiom.2019.07.022_bb0150","series-title":"Structured Clinical Interview for DSM-IV Axis I Disorders (SCID)","author":"First","year":"1997"},{"issue":"3","key":"10.1016\/j.ebiom.2019.07.022_bb0155","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1007\/s12021-016-9299-4","article-title":"DPABI: data processing & analysis for (resting-state) brain imaging","volume":"14","author":"Yan","year":"2016","journal-title":"Neuroinformatics"},{"issue":"1","key":"10.1016\/j.ebiom.2019.07.022_bb0160","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/j.jneumeth.2008.04.012","article-title":"An improved approach to detection of amplitude of low-frequency fluctuation (ALFF) for resting-state fMRI: fractional ALFF","volume":"172","author":"Zou","year":"2008","journal-title":"J Neurosci Methods"},{"key":"10.1016\/j.ebiom.2019.07.022_bb0165","doi-asserted-by":"crossref","first-page":"2142","DOI":"10.1016\/j.neuroimage.2011.10.018","article-title":"Spurious but systematic correlations in functional connectivity MRI networks arise from subject motion","volume":"59","author":"Power","year":"2012","journal-title":"Neuroimage"},{"issue":"1","key":"10.1016\/j.ebiom.2019.07.022_bb0170","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/S0920-9964(02)00526-1","article-title":"Caudate and putamen volumes in good and poor outcome patients with schizophrenia","volume":"64","author":"Buchsbaum","year":"2003","journal-title":"Schizophr Res"},{"issue":"5","key":"10.1016\/j.ebiom.2019.07.022_bb0175","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/j.tins.2007.03.007","article-title":"Behavioral dopamine signals","volume":"30","author":"Schultz","year":"2007","journal-title":"Trends Neurosci"},{"issue":"3","key":"10.1016\/j.ebiom.2019.07.022_bb0180","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1093\/schbul\/sbp006","article-title":"The dopamine hypothesis of schizophrenia: version III--the final common pathway","volume":"35","author":"Howes","year":"2009","journal-title":"Schizophr Bull"},{"issue":"1","key":"10.1016\/j.ebiom.2019.07.022_bb0185","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1016\/j.schres.2012.11.003","article-title":"Larger putamen size in antipsychotic-naive individuals with schizotypal personality disorder","volume":"143","author":"Chemerinski","year":"2013","journal-title":"Schizophr Res"}],"container-title":["eBioMedicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2352396419304566?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2352396419304566?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,6]],"date-time":"2025-11-06T18:54:50Z","timestamp":1762455290000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2352396419304566"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,8]]},"references-count":37,"alternative-id":["S2352396419304566"],"URL":"https:\/\/doi.org\/10.1016\/j.ebiom.2019.07.022","relation":{},"ISSN":["2352-3964"],"issn-type":[{"value":"2352-3964","type":"print"}],"subject":[],"published":{"date-parts":[[2019,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Enhanced baseline activity in the left ventromedial putamen predicts individual treatment response in drug-naive, first-episode schizophrenia: Results from two independent study samples","name":"articletitle","label":"Article Title"},{"value":"eBioMedicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ebiom.2019.07.022","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}]}}