{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T12:09:38Z","timestamp":1789992578213,"version":"4.0.1"},"reference-count":63,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2019,9,1]],"date-time":"2019-09-01T00:00:00Z","timestamp":1567296000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,9,1]],"date-time":"2019-09-01T00:00:00Z","timestamp":1567296000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2019,8,14]],"date-time":"2019-08-14T00:00:00Z","timestamp":1565740800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["thelancet.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["EBioMedicine"],"published-print":{"date-parts":[[2019,9]]},"DOI":"10.1016\/j.ebiom.2019.08.031","type":"journal-article","created":{"date-parts":[[2019,8,21]],"date-time":"2019-08-21T18:48:53Z","timestamp":1566413333000},"page":"553-562","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"special_numbering":"C","title":["Transplantation studies reveal internuclear transfer of toxic RNA in engrafted muscles of myotonic dystrophy 1 mice"],"prefix":"10.1016","volume":"47","author":[{"given":"Ricardo","family":"Mondragon-Gonzalez","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karim","family":"Azzag","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sridhar","family":"Selvaraj","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ami","family":"Yamamoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9412-1118","authenticated-orcid":false,"given":"Rita C.R.","family":"Perlingeiro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ebiom.2019.08.031_bb0005","series-title":"Myotonic dystrophy","author":"Harper","year":"2001"},{"key":"10.1016\/j.ebiom.2019.08.031_bb0010","doi-asserted-by":"crossref","first-page":"3175","DOI":"10.1093\/brain\/awp236","article-title":"Prevalence of genetic muscle disease in Northern England: in-depth analysis of a muscle clinic population","volume":"132","author":"Norwood","year":"2009","journal-title":"Brain"},{"issue":"8","key":"10.1016\/j.ebiom.2019.08.031_bb0015","doi-asserted-by":"crossref","first-page":"1248","DOI":"10.1212\/01.wnl.0000208513.48550.08","article-title":"Clinical characteristics of myotonic dystrophy type 1 patients with small CTG expansions","volume":"66","author":"Arsenault","year":"2006","journal-title":"Neurology."},{"issue":"2","key":"10.1016\/j.ebiom.2019.08.031_bb0020","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1007\/s00415-014-7570-x","article-title":"Natural history of skeletal muscle involvement in myotonic dystrophy type 1: a retrospective study in 204 cases","volume":"262","author":"Bouchard","year":"2015","journal-title":"J Neurol"},{"issue":"5049","key":"10.1016\/j.ebiom.2019.08.031_bb0025","doi-asserted-by":"crossref","first-page":"1253","DOI":"10.1126\/science.1546325","article-title":"Myotonic dystrophy mutation: an unstable CTG repeat in the 3\u2032 untranslated region of the gene","volume":"255","author":"Mahadevan","year":"1992","journal-title":"Science."},{"issue":"19","key":"10.1016\/j.ebiom.2019.08.031_bb0030","doi-asserted-by":"crossref","first-page":"5463","DOI":"10.1093\/nar\/gkg767","article-title":"Structures of trinucleotide repeats in human transcripts and their functional implications","volume":"31","author":"Jasinska","year":"2003","journal-title":"Nucleic Acids Res"},{"issue":"49","key":"10.1016\/j.ebiom.2019.08.031_bb0035","doi-asserted-by":"crossref","first-page":"31079","DOI":"10.1074\/jbc.272.49.31079","article-title":"CUG repeats present in myotonin kinase RNA form metastable \"slippery\" hairpins","volume":"272","author":"Napierala","year":"1997","journal-title":"J Biol Chem"},{"issue":"6","key":"10.1016\/j.ebiom.2019.08.031_bb0040","doi-asserted-by":"crossref","first-page":"995","DOI":"10.1083\/jcb.128.6.995","article-title":"Foci of trinucleotide repeat transcripts in nuclei of myotonic dystrophy cells and tissues","volume":"128","author":"Taneja","year":"1995","journal-title":"J Cell Biol"},{"issue":"1","key":"10.1016\/j.ebiom.2019.08.031_bb0045","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1017\/S1355838200991544","article-title":"Expanded CUG repeat RNAs form hairpins that activate the double-stranded RNA-dependent protein kinase PKR","volume":"6","author":"Tian","year":"2000","journal-title":"Rna."},{"issue":"4","key":"10.1016\/j.ebiom.2019.08.031_bb0050","doi-asserted-by":"crossref","first-page":"594","DOI":"10.1016\/j.bbadis.2014.05.019","article-title":"Myotonic dystrophies: an update on clinical aspects, genetic, pathology, and molecular pathomechanisms","volume":"1852","author":"Meola","year":"2015","journal-title":"Biochim Biophys Acta"},{"issue":"6","key":"10.1016\/j.ebiom.2019.08.031_bb0055","doi-asserted-by":"crossref","first-page":"1312","DOI":"10.1093\/hmg\/ddr568","article-title":"Muscle weakness in myotonic dystrophy associated with misregulated splicing and altered gating of Ca(V)1.1 calcium channel","volume":"21","author":"Tang","year":"2012","journal-title":"Hum Mol Genet"},{"issue":"5652","key":"10.1016\/j.ebiom.2019.08.031_bb0060","doi-asserted-by":"crossref","first-page":"1978","DOI":"10.1126\/science.1088583","article-title":"A muscleblind knockout model for myotonic dystrophy","volume":"302","author":"Kanadia","year":"2003","journal-title":"Science."},{"issue":"4","key":"10.1016\/j.ebiom.2019.08.031_bb0065","doi-asserted-by":"crossref","first-page":"e52","DOI":"10.1371\/journal.pgen.0030052","article-title":"CTG trinucleotide repeat \"big jumps\": large expansions, small mice","volume":"3","author":"Gomes-Pereira","year":"2007","journal-title":"PLoS Genet"},{"issue":"5485","key":"10.1016\/j.ebiom.2019.08.031_bb0070","doi-asserted-by":"crossref","first-page":"1769","DOI":"10.1126\/science.289.5485.1769","article-title":"Myotonic dystrophy in transgenic mice expressing an expanded CUG repeat","volume":"289","author":"Mankodi","year":"2000","journal-title":"Science."},{"issue":"7","key":"10.1016\/j.ebiom.2019.08.031_bb0075","doi-asserted-by":"crossref","first-page":"2646","DOI":"10.1073\/pnas.0708519105","article-title":"Expanded CTG repeats within the DMPK 3' UTR causes severe skeletal muscle wasting in an inducible mouse model for myotonic dystrophy","volume":"105","author":"Orengo","year":"2008","journal-title":"Proc Natl Acad Sci USA"},{"issue":"33","key":"10.1016\/j.ebiom.2019.08.031_bb0080","doi-asserted-by":"crossref","first-page":"13915","DOI":"10.1073\/pnas.0905780106","article-title":"Triplet-repeat oligonucleotide-mediated reversal of RNA toxicity in myotonic dystrophy","volume":"106","author":"Mulders","year":"2009","journal-title":"Proc Natl Acad Sci USA"},{"issue":"2","key":"10.1016\/j.ebiom.2019.08.031_bb0085","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1124\/jpet.115.226969","article-title":"Identification and characterization of modified antisense oligonucleotides targeting DMPK in mice and nonhuman primates for the treatment of myotonic dystrophy type 1","volume":"355","author":"Pandey","year":"2015","journal-title":"J Pharmacol Exp Ther"},{"issue":"7409","key":"10.1016\/j.ebiom.2019.08.031_bb0090","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1038\/nature11362","article-title":"Targeting nuclear RNA for in vivo correction of myotonic dystrophy","volume":"488","author":"Wheeler","year":"2012","journal-title":"Nature."},{"issue":"3","key":"10.1016\/j.ebiom.2019.08.031_bb0095","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1111\/nan.12198","article-title":"Invited review: stem cells and muscle diseases: advances in cell therapy strategies","volume":"41","author":"Negroni","year":"2015","journal-title":"Neuropathol Appl Neurobiol"},{"issue":"8","key":"10.1016\/j.ebiom.2019.08.031_bb0100","doi-asserted-by":"crossref","first-page":"1222","DOI":"10.1038\/cdd.2009.160","article-title":"Cell therapy strategies and improvements for muscular dystrophy","volume":"17","author":"Quattrocelli","year":"2010","journal-title":"Cell Death Differ"},{"issue":"140","key":"10.1016\/j.ebiom.2019.08.031_bb0105","doi-asserted-by":"crossref","first-page":"140ra89","DOI":"10.1126\/scitranslmed.3003541","article-title":"Transplantation of genetically corrected human iPSC-derived progenitors in mice with limb-girdle muscular dystrophy","volume":"4","author":"Tedesco","year":"2012","journal-title":"Sci Transl Med"},{"issue":"7119","key":"10.1016\/j.ebiom.2019.08.031_bb0110","doi-asserted-by":"crossref","first-page":"574","DOI":"10.1038\/nature05282","article-title":"Mesoangioblast stem cells ameliorate muscle function in dystrophic dogs","volume":"444","author":"Sampaolesi","year":"2006","journal-title":"Nature."},{"issue":"1","key":"10.1016\/j.ebiom.2019.08.031_bb0115","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/j.cell.2008.05.049","article-title":"Highly efficient, functional engraftment of skeletal muscle stem cells in dystrophic muscles","volume":"134","author":"Cerletti","year":"2008","journal-title":"Cell."},{"issue":"8","key":"10.1016\/j.ebiom.2019.08.031_bb0120","doi-asserted-by":"crossref","first-page":"1611","DOI":"10.1002\/stem.1402","article-title":"A new immuno-, dystrophin-deficient model, the NSG-mdx(4Cv) mouse, provides evidence for functional improvement following allogeneic satellite cell transplantation","volume":"31","author":"Arpke","year":"2013","journal-title":"Stem Cells"},{"issue":"6203","key":"10.1016\/j.ebiom.2019.08.031_bb0125","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1038\/337176a0","article-title":"Conversion of mdx myofibres from dystrophin-negative to -positive by injection of normal myoblasts","volume":"337","author":"Partridge","year":"1989","journal-title":"Nature."},{"issue":"5","key":"10.1016\/j.ebiom.2019.08.031_bb0130","doi-asserted-by":"crossref","first-page":"610","DOI":"10.1016\/j.stem.2012.02.015","article-title":"Human ES- and iPS-derived myogenic progenitors restore DYSTROPHIN and improve contractility upon transplantation in dystrophic mice","volume":"10","author":"Darabi","year":"2012","journal-title":"Cell Stem Cell"},{"issue":"7","key":"10.1016\/j.ebiom.2019.08.031_bb0135","doi-asserted-by":"crossref","first-page":"530","DOI":"10.1089\/scd.2015.0289","article-title":"Myeloid engraftment in humanized mice: impact of granulocyte-colony stimulating factor treatment and transgenic mouse strain","volume":"25","author":"Coughlan","year":"2016","journal-title":"Stem Cells Dev"},{"issue":"10","key":"10.1016\/j.ebiom.2019.08.031_bb0140","doi-asserted-by":"crossref","first-page":"6477","DOI":"10.4049\/jimmunol.174.10.6477","article-title":"Human lymphoid and myeloid cell development in NOD\/LtSz-scid IL2R gamma null mice engrafted with mobilized human hemopoietic stem cells","volume":"174","author":"Shultz","year":"2005","journal-title":"J Immunol"},{"key":"10.1016\/j.ebiom.2019.08.031_bb0145","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1186\/1472-6750-4-33","article-title":"Dynamic in vivo imaging and cell tracking using a histone fluorescent protein fusion in mice","volume":"4","author":"Hadjantonakis","year":"2004","journal-title":"BMC Biotechnol"},{"issue":"5","key":"10.1016\/j.ebiom.2019.08.031_bb0150","doi-asserted-by":"crossref","first-page":"1347","DOI":"10.1113\/jphysiol.2012.246546","article-title":"Age-dependent chloride channel expression in skeletal muscle fibres of normal and HSA(LR) myotonic mice","volume":"591","author":"DiFranco","year":"2013","journal-title":"J Physiol"},{"key":"10.1016\/j.ebiom.2019.08.031_bb0155","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/j.semcdb.2017.10.031","article-title":"Myogenic progenitor specification from pluripotent stem cells","volume":"72","author":"Magli","year":"2017","journal-title":"Semin Cell Dev Biol"},{"issue":"10","key":"10.1016\/j.ebiom.2019.08.031_bb0160","doi-asserted-by":"crossref","first-page":"1580","DOI":"10.1002\/stem.715","article-title":"Inducible cassette exchange: a rapid and efficient system enabling conditional gene expression in embryonic stem and primary cells","volume":"29","author":"Iacovino","year":"2011","journal-title":"Stem Cells"},{"key":"10.1016\/j.ebiom.2019.08.031_bb0165","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1007\/978-1-4939-3810-0_14","article-title":"Myogenic progenitors from mouse pluripotent stem cells for muscle regeneration","volume":"1460","author":"Magli","year":"2016","journal-title":"Methods Mol Biol"},{"issue":"10","key":"10.1016\/j.ebiom.2019.08.031_bb0170","doi-asserted-by":"crossref","first-page":"4346","DOI":"10.1073\/pnas.1808303116","article-title":"Pluripotent stem cell-derived myogenic progenitors remodel their molecular signature upon in vivo engraftment","volume":"116","author":"Incitti","year":"2019","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.ebiom.2019.08.031_bb0175","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1007\/978-1-4939-3810-0_12","article-title":"Flow cytometry and transplantation-based quantitative assays for satellite cell self-renewal and differentiation","volume":"1460","author":"Arpke","year":"2016","journal-title":"Methods Mol Biol"},{"issue":"5","key":"10.1016\/j.ebiom.2019.08.031_bb0180","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1002\/stem.625","article-title":"Assessment of the myogenic stem cell compartment following transplantation of Pax3\/Pax7-induced embryonic stem cell-derived progenitors","volume":"29","author":"Darabi","year":"2011","journal-title":"Stem Cells"},{"key":"10.1016\/j.ebiom.2019.08.031_bb0185","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1007\/978-1-4939-3810-0_5","article-title":"Inducing and evaluating skeletal muscle injury by notexin and barium chloride","volume":"1460","author":"Tierney","year":"2016","journal-title":"Methods Mol Biol"},{"key":"10.1016\/j.ebiom.2019.08.031_bb0190","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1007\/978-1-4939-3810-0_3","article-title":"Freeze injury of the tibialis anterior muscle","volume":"1460","author":"Le","year":"2016","journal-title":"Methods Mol Biol"},{"issue":"5","key":"10.1016\/j.ebiom.2019.08.031_bb0195","doi-asserted-by":"crossref","first-page":"907","DOI":"10.1016\/j.cell.2014.01.042","article-title":"Stable C0T-1 repeat RNA is abundant and is associated with euchromatic interphase chromosomes","volume":"156","author":"Hall","year":"2014","journal-title":"Cell."},{"issue":"6","key":"10.1016\/j.ebiom.2019.08.031_bb0200","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1177\/1090820X12452422","article-title":"Application of fluorescent in situ hybridization in the mouse xenograft model of human fat grafting","volume":"32","author":"Han","year":"2012","journal-title":"Aesthet Surg J"},{"key":"10.1016\/j.ebiom.2019.08.031_bb0205","article-title":"Phenylbutazone induces expression of MBNL1 and suppresses formation of MBNL1-CUG RNA foci in a mouse model of myotonic dystrophy","volume":"6","author":"Chen","year":"2016","journal-title":"Sci Rep"},{"issue":"44","key":"10.1016\/j.ebiom.2019.08.031_bb0210","doi-asserted-by":"crossref","first-page":"18551","DOI":"10.1073\/pnas.0903234106","article-title":"Pentamidine reverses the splicing defects associated with myotonic dystrophy","volume":"106","author":"Warf","year":"2009","journal-title":"Proc Natl Acad Sci USA"},{"issue":"23","key":"10.1016\/j.ebiom.2019.08.031_bb0215","doi-asserted-by":"crossref","first-page":"2834","DOI":"10.1093\/hmg\/ddm239","article-title":"Molecular mechanisms responsible for aberrant splicing of SERCA1 in myotonic dystrophy type 1","volume":"16","author":"Hino","year":"2007","journal-title":"Hum Mol Genet"},{"key":"10.1016\/j.ebiom.2019.08.031_bb0220","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1016\/j.nbd.2014.05.026","article-title":"LDB3 splicing abnormalities are specific to skeletal muscles of patients with myotonic dystrophy type 1 and alter its PKC binding affinity","volume":"69","author":"Yamashita","year":"2014","journal-title":"Neurobiol Dis"},{"issue":"5900","key":"10.1016\/j.ebiom.2019.08.031_bb0225","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1038\/301527a0","article-title":"A severe combined immunodeficiency mutation in the mouse","volume":"301","author":"Bosma","year":"1983","journal-title":"Nature."},{"issue":"3","key":"10.1016\/j.ebiom.2019.08.031_bb0230","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/1074-7613(95)90047-0","article-title":"Defective lymphoid development in mice lacking expression of the common cytokine receptor gamma chain","volume":"2","author":"Cao","year":"1995","journal-title":"Immunity."},{"issue":"5","key":"10.1016\/j.ebiom.2019.08.031_bb0235","doi-asserted-by":"crossref","first-page":"1565","DOI":"10.1182\/blood-2005-02-0516","article-title":"Development of functional human blood and immune systems in NOD\/SCID\/IL2 receptor {gamma} chain(null) mice","volume":"106","author":"Ishikawa","year":"2005","journal-title":"Blood."},{"issue":"7","key":"10.1016\/j.ebiom.2019.08.031_bb0240","doi-asserted-by":"crossref","DOI":"10.1242\/dmm.034728","article-title":"Recapitulating muscle disease phenotypes with myotonic dystrophy 1 iPS cells: a tool for disease modeling and drug discovery","volume":"11","author":"Mondragon-Gonzalez","year":"2018","journal-title":"Dis Model Mech"},{"issue":"15","key":"10.1016\/j.ebiom.2019.08.031_bb0245","doi-asserted-by":"crossref","first-page":"2189","DOI":"10.1093\/hmg\/ddi223","article-title":"Altered mRNA splicing of the skeletal muscle ryanodine receptor and sarcoplasmic\/endoplasmic reticulum Ca2+-ATPase in myotonic dystrophy type 1","volume":"14","author":"Kimura","year":"2005","journal-title":"Hum Mol Genet"},{"issue":"6","key":"10.1016\/j.ebiom.2019.08.031_bb0250","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1083\/jcb.201108113","article-title":"The RNA-binding protein Staufen1 is increased in DM1 skeletal muscle and promotes alternative pre-mRNA splicing","volume":"196","author":"Ravel-Chapuis","year":"2012","journal-title":"J Cell Biol"},{"issue":"10","key":"10.1016\/j.ebiom.2019.08.031_bb0255","doi-asserted-by":"crossref","first-page":"1703","DOI":"10.1242\/jcs.073270","article-title":"Stochastic and reversible aggregation of mRNA with expanded CUG-triplet repeats","volume":"124","author":"Querido","year":"2011","journal-title":"J Cell Sci"},{"issue":"12","key":"10.1016\/j.ebiom.2019.08.031_bb0260","doi-asserted-by":"crossref","first-page":"3866","DOI":"10.1093\/nar\/gki698","article-title":"HnRNP H inhibits nuclear export of mRNA containing expanded CUG repeats and a distal branch point sequence","volume":"33","author":"Kim","year":"2005","journal-title":"Nucleic Acids Res"},{"issue":"14","key":"10.1016\/j.ebiom.2019.08.031_bb0265","doi-asserted-by":"crossref","first-page":"7388","DOI":"10.1073\/pnas.94.14.7388","article-title":"Expansion of a CUG trinucleotide repeat in the 3\u2032 untranslated region of myotonic dystrophy protein kinase transcripts results in nuclear retention of transcripts","volume":"94","author":"Davis","year":"1997","journal-title":"Proc Natl Acad Sci USA"},{"issue":"11","key":"10.1016\/j.ebiom.2019.08.031_bb0270","doi-asserted-by":"crossref","first-page":"7186","DOI":"10.1093\/nar\/gku352","article-title":"DDX6 regulates sequestered nuclear CUG-expanded DMPK-mRNA in dystrophia myotonica type 1","volume":"42","author":"Pettersson","year":"2014","journal-title":"Nucleic Acids Res"},{"issue":"12","key":"10.1016\/j.ebiom.2019.08.031_bb0275","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0003968","article-title":"Cytoplasmic CUG RNA foci are insufficient to elicit key DM1 features","volume":"3","author":"Dansithong","year":"2008","journal-title":"PloS One"},{"issue":"7657","key":"10.1016\/j.ebiom.2019.08.031_bb0280","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1038\/nature22386","article-title":"RNA phase transitions in repeat expansion disorders","volume":"546","author":"Jain","year":"2017","journal-title":"Nature."},{"issue":"4","key":"10.1016\/j.ebiom.2019.08.031_bb0285","doi-asserted-by":"crossref","first-page":"2433","DOI":"10.1093\/nar\/gkv029","article-title":"Molecular mechanisms in DM1 - a focus on foci","volume":"43","author":"Pettersson","year":"2015","journal-title":"Nucleic Acids Res"},{"issue":"2","key":"10.1016\/j.ebiom.2019.08.031_bb0290","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1042\/BJ20130870","article-title":"Transcriptionally correlated subcellular dynamics of MBNL1 during lens development and their implication for the molecular pathology of myotonic dystrophy type 1","volume":"458","author":"Coleman","year":"2014","journal-title":"Biochem J"},{"issue":"9","key":"10.1016\/j.ebiom.2019.08.031_bb0295","doi-asserted-by":"crossref","first-page":"2294","DOI":"10.1016\/j.celrep.2018.02.025","article-title":"Ubiquitination of MBNL1 is required for its cytoplasmic localization and function in promoting neurite outgrowth","volume":"22","author":"Wang","year":"2018","journal-title":"Cell Rep"},{"issue":"15","key":"10.1016\/j.ebiom.2019.08.031_bb0300","doi-asserted-by":"crossref","first-page":"4125","DOI":"10.1093\/hmg\/ddu129","article-title":"Nuclear protein spreading: implication for pathophysiology of neuromuscular diseases","volume":"23","author":"Ferreboeuf","year":"2014","journal-title":"Hum Mol Genet"},{"issue":"9","key":"10.1016\/j.ebiom.2019.08.031_bb0305","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1016\/j.molmed.2011.05.004","article-title":"Myotonic dystrophy mouse models: towards rational therapy development","volume":"17","author":"Gomes-Pereira","year":"2011","journal-title":"Trends Mol Med"},{"key":"10.1016\/j.ebiom.2019.08.031_bb0310","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/B978-0-12-394596-9.00004-4","article-title":"Animal models of muscular dystrophy","volume":"105","author":"Ng","year":"2012","journal-title":"Prog Mol Biol Transl Sci"},{"issue":"5938","key":"10.1016\/j.ebiom.2019.08.031_bb0315","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1126\/science.1173110","article-title":"Reversal of RNA dominance by displacement of protein sequestered on triplet repeat RNA","volume":"325","author":"Wheeler","year":"2009","journal-title":"Science."}],"container-title":["EBioMedicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2352396419305535?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2352396419305535?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,6]],"date-time":"2025-11-06T18:57:16Z","timestamp":1762455436000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2352396419305535"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,9]]},"references-count":63,"alternative-id":["S2352396419305535"],"URL":"https:\/\/doi.org\/10.1016\/j.ebiom.2019.08.031","relation":{},"ISSN":["2352-3964"],"issn-type":[{"value":"2352-3964","type":"print"}],"subject":[],"published":{"date-parts":[[2019,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Transplantation studies reveal internuclear transfer of toxic RNA in engrafted muscles of myotonic dystrophy 1 mice","name":"articletitle","label":"Article Title"},{"value":"EBioMedicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ebiom.2019.08.031","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}]}}