{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T19:51:51Z","timestamp":1792612311862,"version":"4.5.0"},"reference-count":50,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,10,1]],"date-time":"2020-10-01T00:00:00Z","timestamp":1601510400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,10,1]],"date-time":"2020-10-01T00:00:00Z","timestamp":1601510400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2020,9,2]],"date-time":"2020-09-02T00:00:00Z","timestamp":1599004800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100005407","name":"Food and Health Bureau","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005407","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002920","name":"Research Grants Council, University Grants Committee","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002920","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003803","name":"University of Hong Kong","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003803","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["thelancet.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["EBioMedicine"],"published-print":{"date-parts":[[2020,10]]},"DOI":"10.1016\/j.ebiom.2020.103008","type":"journal-article","created":{"date-parts":[[2020,9,24]],"date-time":"2020-09-24T03:48:57Z","timestamp":1600919337000},"page":"103008","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":10,"special_numbering":"C","title":["Persistent lentivirus infection induces early myeloid suppressor cells expansion to subvert protective memory CD8 T cell response\u2730,\u2730\u2730"],"prefix":"10.1016","volume":"60","author":[{"given":"Li","family":"Liu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qingqing","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jie","family":"Peng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"Fang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhiwu","family":"Tan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hangying","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kayi","family":"Kwan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenji","family":"Nishiura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianguo","family":"Liang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hauyee","family":"Kwok","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhenglong","family":"Du","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiaze","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kang","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kwok-Yung","family":"Yuen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hui","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhiwei","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"5922","key":"10.1016\/j.ebiom.2020.103008_bib0001","doi-asserted-by":"crossref","first-page":"1726","DOI":"10.1126\/science.1168676","article-title":"Visualizing antigen-specific and infected cells in situ predicts outcomes in early viral infection","volume":"323","author":"Li","year":"2009","journal-title":"Science"},{"issue":"7286","key":"10.1016\/j.ebiom.2020.103008_bib0002","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1038\/nature08898","article-title":"Immunology and the elusive AIDS vaccine","volume":"464","author":"Virgin","year":"2010","journal-title":"Nature"},{"issue":"1\u20133","key":"10.1016\/j.ebiom.2020.103008_bib0003","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1007\/s12026-010-8162-1","article-title":"Translating insights from persistent LCMV infection into anti-HIV immunity","volume":"48","author":"Wilson","year":"2010","journal-title":"Immunol Res"},{"issue":"11","key":"10.1016\/j.ebiom.2020.103008_bib0004","doi-asserted-by":"crossref","first-page":"1301","DOI":"10.1038\/nm1492","article-title":"Interleukin-10 determines viral clearance or persistence in vivo","volume":"12","author":"Brooks","year":"2006","journal-title":"Nat Med"},{"issue":"7077","key":"10.1016\/j.ebiom.2020.103008_bib0005","doi-asserted-by":"crossref","first-page":"682","DOI":"10.1038\/nature04444","article-title":"Restoring function in exhausted CD8 T cells during chronic viral infection","volume":"439","author":"Barber","year":"2006","journal-title":"Nature"},{"issue":"4","key":"10.1016\/j.ebiom.2020.103008_bib0006","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1111\/j.1365-2567.2010.03255.x","article-title":"T-cell exhaustion: characteristics, causes and conversion","volume":"129","author":"Yi","year":"2010","journal-title":"Immunology"},{"issue":"12","key":"10.1016\/j.ebiom.2020.103008_bib0007","doi-asserted-by":"crossref","first-page":"2205","DOI":"10.1084\/jem.188.12.2205","article-title":"Viral immune evasion due to persistence of activated T cells without effector function","volume":"188","author":"Zajac","year":"1998","journal-title":"J Exp Med"},{"issue":"33","key":"10.1016\/j.ebiom.2020.103008_bib0008","doi-asserted-by":"crossref","first-page":"14733","DOI":"10.1073\/pnas.1009731107","article-title":"Cooperation of Tim-3 and PD-1 in CD8 T-cell exhaustion during chronic viral infection","volume":"107","author":"Jin","year":"2010","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"1","key":"10.1016\/j.ebiom.2020.103008_bib0009","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1146\/annurev-virology-100114-055226","article-title":"Innate and Adaptive Immune Regulation During Chronic Viral Infections","volume":"2","author":"Zuniga","year":"2015","journal-title":"Annu Rev Virol"},{"issue":"1","key":"10.1016\/j.ebiom.2020.103008_bib0010","doi-asserted-by":"crossref","first-page":"1459","DOI":"10.1038\/s41467-017-01669-z","article-title":"Dengue virus-reactive CD8(+) T cells mediate cross-protection against subsequent Zika virus challenge","volume":"8","author":"Wen","year":"2017","journal-title":"Nat Commun"},{"issue":"9","key":"10.1016\/j.ebiom.2020.103008_bib0011","doi-asserted-by":"crossref","first-page":"1128","DOI":"10.1038\/nm.2447","article-title":"CD8+ cellular immunity mediates rAd5 vaccine protection against Ebola virus infection of nonhuman primates","volume":"17","author":"Sullivan","year":"2011","journal-title":"Nat Med"},{"issue":"5258","key":"10.1016\/j.ebiom.2020.103008_bib0012","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1126\/science.272.5258.54","article-title":"Immunological memory and protective immunity: understanding their relation","volume":"272","author":"Ahmed","year":"1996","journal-title":"Science"},{"issue":"5","key":"10.1016\/j.ebiom.2020.103008_bib0013","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1016\/j.immuni.2005.03.005","article-title":"Dendritic cells maximize the memory CD8 T cell response to infection","volume":"22","author":"Zammit","year":"2005","journal-title":"Immunity"},{"issue":"8","key":"10.1016\/j.ebiom.2020.103008_bib0014","doi-asserted-by":"crossref","first-page":"2199","DOI":"10.1002\/1521-4141(200208)32:8<2199::AID-IMMU2199>3.0.CO;2-L","article-title":"CD8 lethargy in the absence of CD4 help","volume":"32","author":"Bourgeois","year":"2002","journal-title":"Eur J Immunol"},{"issue":"5617","key":"10.1016\/j.ebiom.2020.103008_bib0015","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1126\/science.1082305","article-title":"Requirement for CD4 T cell help in generating functional CD8 T cell memory","volume":"300","author":"Shedlock","year":"2003","journal-title":"Science"},{"issue":"5617","key":"10.1016\/j.ebiom.2020.103008_bib0016","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1126\/science.1083317","article-title":"Defective CD8 T cell memory following acute infection without CD4 T cell help","volume":"300","author":"Sun","year":"2003","journal-title":"Science"},{"issue":"12","key":"10.1016\/j.ebiom.2020.103008_bib0017","doi-asserted-by":"crossref","first-page":"2763","DOI":"10.1084\/jem.20081398","article-title":"Tim-3 expression defines a novel population of dysfunctional T cells with highly elevated frequencies in progressive HIV-1 infection","volume":"205","author":"Jones","year":"2008","journal-title":"J Exp Med"},{"issue":"21","key":"10.1016\/j.ebiom.2020.103008_bib0018","doi-asserted-by":"crossref","first-page":"6010","DOI":"10.1158\/0008-5472.CAN-14-0473","article-title":"Vaccine-elicited CD8+ T cells cure mesothelioma by overcoming tumor-induced immunosuppressive environment","volume":"74","author":"Tan","year":"2014","journal-title":"Cancer Res"},{"key":"10.1016\/j.ebiom.2020.103008_bib0019","doi-asserted-by":"crossref","first-page":"1895","DOI":"10.3389\/fimmu.2017.01895","article-title":"Monocytic Myeloid-Derived Suppressor Cells in Chronic Infections","volume":"8","author":"Dorhoi","year":"2017","journal-title":"Front Immunol"},{"issue":"5","key":"10.1016\/j.ebiom.2020.103008_bib0020","doi-asserted-by":"crossref","first-page":"2283","DOI":"10.4049\/jimmunol.1501881","article-title":"Hepatitis C Virus-Induced Myeloid-Derived Suppressor Cells Suppress NK Cell IFN-gamma Production by Altering Cellular Metabolism via Arginase-1","volume":"196","author":"Goh","year":"2016","journal-title":"J Immunol"},{"issue":"3","key":"10.1016\/j.ebiom.2020.103008_bib0021","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1038\/nri2506","article-title":"Myeloid-derived suppressor cells as regulators of the immune system","volume":"9","author":"Gabrilovich","year":"2009","journal-title":"Nat Rev Immunol"},{"issue":"19","key":"10.1016\/j.ebiom.2020.103008_bib0022","doi-asserted-by":"crossref","first-page":"7503","DOI":"10.1158\/0008-5472.CAN-09-2152","article-title":"Regulatory myeloid suppressor cells in health and disease","volume":"69","author":"Nagaraj","year":"2009","journal-title":"Cancer Res"},{"issue":"10","key":"10.1016\/j.ebiom.2020.103008_bib0023","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1038\/nrc3581","article-title":"History of myeloid-derived suppressor cells","volume":"13","author":"Talmadge","year":"2013","journal-title":"Nat Rev Cancer"},{"issue":"2","key":"10.1016\/j.ebiom.2020.103008_bib0024","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1016\/j.immuni.2012.10.022","article-title":"Chronic but not acute virus infection induces sustained expansion of myeloid suppressor cell numbers that inhibit viral-specific T cell immunity","volume":"38","author":"Norris","year":"2013","journal-title":"Immunity"},{"issue":"2","key":"10.1016\/j.ebiom.2020.103008_bib0025","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1002\/hep.24700","article-title":"Myeloid suppressor cells induced by hepatitis C virus suppress T-cell responses through the production of reactive oxygen species","volume":"55","author":"Tacke","year":"2012","journal-title":"Hepatology"},{"issue":"1","key":"10.1016\/j.ebiom.2020.103008_bib0026","doi-asserted-by":"crossref","DOI":"10.1080\/2162402X.2018.1518672","article-title":"Virotherapy-recruited PMN-MDSC infiltration of mesothelioma blocks antitumor CTL by IL-10-mediated dendritic cell suppression","volume":"8","author":"Tan","year":"2019","journal-title":"Oncoimmunology"},{"issue":"2","key":"10.1016\/j.ebiom.2020.103008_bib0027","doi-asserted-by":"crossref","first-page":"156","DOI":"10.3109\/00365521.2010.516450","article-title":"Up-regulated myeloid-derived suppressor cell contributes to hepatocellular carcinoma development by impairing dendritic cell function","volume":"46","author":"Hu","year":"2011","journal-title":"Scand J Gastroenterol"},{"issue":"2","key":"10.1016\/j.ebiom.2020.103008_bib0028","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1038\/s41590-017-0022-x","article-title":"Myeloid-derived suppressor cells coming of age","volume":"19","author":"Veglia","year":"2018","journal-title":"Nat Immunol"},{"issue":"6","key":"10.1016\/j.ebiom.2020.103008_bib0029","doi-asserted-by":"crossref","first-page":"2629","DOI":"10.1172\/JCI64704","article-title":"PD1-based DNA vaccine amplifies HIV-1 GAG-specific CD8+ T cells in mice","volume":"123","author":"Zhou","year":"2013","journal-title":"J Clin Invest"},{"issue":"10","key":"10.1016\/j.ebiom.2020.103008_bib0030","doi-asserted-by":"crossref","first-page":"3760","DOI":"10.1073\/pnas.0500649102","article-title":"A mouse model for study of systemic HIV-1 infection, antiviral immune responses, and neuroinvasiveness","volume":"102","author":"Potash","year":"2005","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.ebiom.2020.103008_bib0031","doi-asserted-by":"crossref","unstructured":"Kelschenbach JL, Saini M, Hadas E, Gu CJ, Chao W, Bentsman G, et\u00a0al. Mice chronically infected with chimeric HIV resist peripheral and brain superinfection: a model of protective immunity to HIV. J Neuroimmune Pharmacol 7(2):380\u20137.","DOI":"10.1007\/s11481-011-9316-1"},{"issue":"2","key":"10.1016\/j.ebiom.2020.103008_bib0032","doi-asserted-by":"crossref","first-page":"757","DOI":"10.4049\/jimmunol.1600759","article-title":"Kinetics of Myeloid-Derived Suppressor Cell Frequency and Function during Simian Immunodeficiency Virus Infection, Combination Antiretroviral Therapy, and Treatment Interruption","volume":"198","author":"Dross","year":"2017","journal-title":"J Immunol"},{"issue":"8","key":"10.1016\/j.ebiom.2020.103008_bib0033","doi-asserted-by":"crossref","first-page":"905","DOI":"10.1097\/QAD.0b013e3281574549","article-title":"Testing antiretroviral drug efficacy in conventional mice infected with chimeric HIV-1","volume":"21","author":"Hadas","year":"2007","journal-title":"AIDS"},{"issue":"4","key":"10.1016\/j.ebiom.2020.103008_bib0034","doi-asserted-by":"crossref","DOI":"10.1172\/jci.insight.123158","article-title":"Anti-spike IgG causes severe acute lung injury by skewing macrophage responses during acute SARS-CoV infection","volume":"4","author":"Liu","year":"2019","journal-title":"JCI Insight"},{"issue":"52","key":"10.1016\/j.ebiom.2020.103008_bib0035","doi-asserted-by":"crossref","first-page":"8660","DOI":"10.1016\/j.vaccine.2007.10.019","article-title":"Vaccine-induced protection from infection of mice by chimeric human immunodeficiency virus type 1, EcoHIV\/NL4-3","volume":"25","author":"Saini","year":"2007","journal-title":"Vaccine"},{"key":"10.1016\/j.ebiom.2020.103008_bib0036","doi-asserted-by":"crossref","unstructured":"Roshorm Y, Cottingham MG, Potash MJ, Volsky DJ, Hanke T. T cells induced by recombinant chimpanzee adenovirus alone and in prime-boost regimens decrease chimeric EcoHIV\/NDK challenge virus load. Eur J Immunol 42(12):3243\u201355.","DOI":"10.1002\/eji.201242624"},{"issue":"3","key":"10.1016\/j.ebiom.2020.103008_bib0037","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1016\/j.cell.2010.09.039","article-title":"Microbial stimulation fully differentiates monocytes to DC-SIGN\/CD209(+) dendritic cells for immune T cell areas","volume":"143","author":"Cheong","year":"2010","journal-title":"Cell"},{"issue":"12","key":"10.1016\/j.ebiom.2020.103008_bib0038","doi-asserted-by":"crossref","first-page":"1237","DOI":"10.1038\/ni.1822","article-title":"Dendritic cell subsets in primary and secondary T cell responses at body surfaces","volume":"10","author":"Heath","year":"2009","journal-title":"Nat Immunol"},{"issue":"8","key":"10.1016\/j.ebiom.2020.103008_bib0039","doi-asserted-by":"crossref","first-page":"3012","DOI":"10.1073\/pnas.1117359109","article-title":"Plasmacytoid dendritic cells control T-cell response to chronic viral infection","volume":"109","author":"Cervantes-Barragan","year":"2012","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"32","key":"10.1016\/j.ebiom.2020.103008_bib0040","doi-asserted-by":"crossref","first-page":"32426","DOI":"10.18632\/oncotarget.5856","article-title":"Antigen spreading-induced CD8+T cells confer protection against the lethal challenge of wild-type malignant mesothelioma by eliminating myeloid-derived suppressor cells","volume":"6","author":"Yu","year":"2015","journal-title":"Oncotarget"},{"issue":"4","key":"10.1016\/j.ebiom.2020.103008_bib0041","doi-asserted-by":"crossref","DOI":"10.1126\/sciimmunol.aah6789","article-title":"Inflammatory monocytes hinder antiviral B cell responses","volume":"1","author":"Sammicheli","year":"2016","journal-title":"Sci Immunol"},{"issue":"9","key":"10.1016\/j.ebiom.2020.103008_bib0042","doi-asserted-by":"crossref","first-page":"3301","DOI":"10.1128\/jvi.62.9.3301-3308.1988","article-title":"Genetic analysis of in vivo-selected viral variants causing chronic infection: importance of mutation in the L RNA segment of lymphocytic choriomeningitis virus","volume":"62","author":"Ahmed","year":"1988","journal-title":"J Virol"},{"issue":"39","key":"10.1016\/j.ebiom.2020.103008_bib0043","doi-asserted-by":"crossref","first-page":"15430","DOI":"10.1073\/pnas.0702579104","article-title":"Viral targeting of fibroblastic reticular cells contributes to immunosuppression and persistence during chronic infection","volume":"104","author":"Mueller","year":"2007","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"8","key":"10.1016\/j.ebiom.2020.103008_bib0044","doi-asserted-by":"crossref","first-page":"4911","DOI":"10.1128\/JVI.77.8.4911-4927.2003","article-title":"Viral persistence alters CD8 T-cell immunodominance and tissue distribution and results in distinct stages of functional impairment","volume":"77","author":"Wherry","year":"2003","journal-title":"J Virol"},{"issue":"3","key":"10.1016\/j.ebiom.2020.103008_bib0045","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1038\/ni889","article-title":"Lineage relationship and protective immunity of memory CD8 T cell subsets","volume":"4","author":"Wherry","year":"2003","journal-title":"Nat Immunol"},{"issue":"6071","key":"10.1016\/j.ebiom.2020.103008_bib0046","doi-asserted-by":"crossref","first-page":"936","DOI":"10.1126\/science.1214935","article-title":"Disease tolerance as a defense strategy","volume":"335","author":"Medzhitov","year":"2012","journal-title":"Science"},{"issue":"21","key":"10.1016\/j.ebiom.2020.103008_bib0047","doi-asserted-by":"crossref","first-page":"8623","DOI":"10.1073\/pnas.0809818106","article-title":"High antigen levels are the cause of T cell exhaustion during chronic viral infection","volume":"106","author":"Mueller","year":"2009","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"12","key":"10.1016\/j.ebiom.2020.103008_bib0048","doi-asserted-by":"crossref","first-page":"7340","DOI":"10.1128\/jvi.67.12.7340-7349.1993","article-title":"Molecular determinants of macrophage tropism and viral persistence: importance of single amino acid changes in the polymerase and glycoprotein of lymphocytic choriomeningitis virus","volume":"67","author":"Matloubian","year":"1993","journal-title":"J Virol"},{"issue":"3","key":"10.1016\/j.ebiom.2020.103008_bib0049","doi-asserted-by":"crossref","first-page":"1477","DOI":"10.1128\/JVI.01759-12","article-title":"Expansion of monocytic myeloid-derived suppressor cells dampens T cell function in HIV-1-seropositive individuals","volume":"87","author":"Qin","year":"2013","journal-title":"J Virol"},{"issue":"1","key":"10.1016\/j.ebiom.2020.103008_bib0050","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1189\/jlb.0407247","article-title":"Use of Ly6G-specific monoclonal antibody to deplete neutrophils in mice","volume":"83","author":"Daley","year":"2008","journal-title":"J Leukoc Biol"}],"container-title":["EBioMedicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2352396420303844?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2352396420303844?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,6]],"date-time":"2025-11-06T19:02:42Z","timestamp":1762455762000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2352396420303844"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,10]]},"references-count":50,"alternative-id":["S2352396420303844"],"URL":"https:\/\/doi.org\/10.1016\/j.ebiom.2020.103008","relation":{},"ISSN":["2352-3964"],"issn-type":[{"value":"2352-3964","type":"print"}],"subject":[],"published":{"date-parts":[[2020,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Persistent lentivirus infection induces early myeloid suppressor cells expansion to subvert protective memory CD8 T cell response\u2730,\u2730\u2730","name":"articletitle","label":"Article Title"},{"value":"EBioMedicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ebiom.2020.103008","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 The Author(s). Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"103008"}}