{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T03:44:37Z","timestamp":1790048677618,"version":"4.0.1"},"reference-count":10,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,6,1]],"date-time":"2022-06-01T00:00:00Z","timestamp":1654041600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,6,1]],"date-time":"2022-06-01T00:00:00Z","timestamp":1654041600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,5,6]],"date-time":"2022-05-06T00:00:00Z","timestamp":1651795200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["thelancet.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["eBioMedicine"],"published-print":{"date-parts":[[2022,6]]},"DOI":"10.1016\/j.ebiom.2022.104070","type":"journal-article","created":{"date-parts":[[2022,5,18]],"date-time":"2022-05-18T23:19:48Z","timestamp":1652915988000},"page":"104070","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"special_numbering":"C","title":["Kwashiorkor \u2013 New evidence in the puzzle of oedema formation"],"prefix":"10.1016","volume":"80","author":[{"given":"Andr\u00e9","family":"Briend","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ebiom.2022.104070_bib0001","article-title":"Kwashiorkor: still an enigma\u2013the search must go on","author":"Briend","year":"2014","journal-title":"CMAM Forum Technical Brief"},{"key":"10.1016\/j.ebiom.2022.104070_bib0002","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1016\/0035-9203(84)90053-1","article-title":"Kwashiorkor revisited: the pathogenesis of oedema in kwashiorkor and its significance","volume":"78","author":"Waterlow","year":"1984","journal-title":"Trans R Soc Trop Med Hyg"},{"key":"10.1016\/j.ebiom.2022.104070_bib0003","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1179\/2046905514Y.0000000154","article-title":"Oedema in kwashiorkor is caused by hypoalbuminaemia","volume":"35","author":"Coulthard","year":"2015","journal-title":"Paediatr Int Child Health"},{"key":"10.1016\/j.ebiom.2022.104070_bib0004","doi-asserted-by":"crossref","first-page":"704","DOI":"10.1113\/jphysiol.2004.066118","article-title":"Revision of the Starling principle: new views of tissue fluid balance","volume":"557","author":"Levick","year":"2004","journal-title":"J Physiol"},{"key":"10.1016\/j.ebiom.2022.104070_bib0005","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1016\/S0140-6736(80)90603-0","article-title":"Albumin and nutritional oedema","volume":"1","author":"Golden","year":"1980","journal-title":"Lancet"},{"key":"10.1016\/j.ebiom.2022.104070_bib0006","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1113\/jphysiol.2004.063511","article-title":"Fluid exchange in the microcirculation","volume":"557","author":"Michel","year":"2004","journal-title":"J Physiol"},{"key":"10.1016\/j.ebiom.2022.104070_bib0007","series-title":"Textbook of Medical Physiology","author":"Guyton","year":"2006"},{"issue":"79","key":"10.1016\/j.ebiom.2022.104070_bib0008","article-title":"The role of albumin and the extracellular matrix on the pathophysiology of oedema formation in severe malnutrition","volume":"7","author":"Gonzales","year":"2022","journal-title":"EBioMedicine"},{"key":"10.1016\/j.ebiom.2022.104070_bib0009","article-title":"Nutritional and other types of oedema, albumin, complex carbohydrates and the interstitium - a response to Malcolm Coulthard's hypothesis: oedema in kwashiorkor is caused by hypo-albuminaemia","author":"Golden","year":"2015","journal-title":"Paediatr Int Child Health"},{"key":"10.1016\/j.ebiom.2022.104070_bib0010","series-title":"Pocket Book of Hospital Care For Children","year":"2013"}],"container-title":["eBioMedicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2352396422002511?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2352396422002511?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,6]],"date-time":"2025-11-06T19:18:07Z","timestamp":1762456687000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2352396422002511"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,6]]},"references-count":10,"alternative-id":["S2352396422002511"],"URL":"https:\/\/doi.org\/10.1016\/j.ebiom.2022.104070","relation":{},"ISSN":["2352-3964"],"issn-type":[{"value":"2352-3964","type":"print"}],"subject":[],"published":{"date-parts":[[2022,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Kwashiorkor \u2013 New evidence in the puzzle of oedema formation","name":"articletitle","label":"Article Title"},{"value":"eBioMedicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ebiom.2022.104070","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"https:\/\/doi.org\/10.1016\/j.ebiom.2022.103991","name":"associatedlink","label":"CrossRef DOI link to the associated document"},{"value":"simple-article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 The Author(s). Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"104070"}}