{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,31]],"date-time":"2026-10-31T15:13:56Z","timestamp":1793459636956,"version":"4.5.0"},"reference-count":43,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,6,21]],"date-time":"2022-06-21T00:00:00Z","timestamp":1655769600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2018YFC1312700"],"award-info":[{"award-number":["2018YFC1312700"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["5R01DK039308-31"],"award-info":[{"award-number":["5R01DK039308-31"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["7R37HL023081-37"],"award-info":[{"award-number":["7R37HL023081-37"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["5P01HL074940-11"],"award-info":[{"award-number":["5P01HL074940-11"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001677","name":"National Institute of Health and Medical Research","doi-asserted-by":"publisher","award":["5R01DK039308-31"],"award-info":[{"award-number":["5R01DK039308-31"]}],"id":[{"id":"10.13039\/501100001677","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001677","name":"National Institute of Health and Medical Research","doi-asserted-by":"publisher","award":["5P01HL074940-11"],"award-info":[{"award-number":["5P01HL074940-11"]}],"id":[{"id":"10.13039\/501100001677","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001677","name":"National Institute of Health and Medical Research","doi-asserted-by":"publisher","award":["7R37HL023081-37"],"award-info":[{"award-number":["7R37HL023081-37"]}],"id":[{"id":"10.13039\/501100001677","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82070296"],"award-info":[{"award-number":["82070296"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81930008"],"award-info":[{"award-number":["81930008"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82102834"],"award-info":[{"award-number":["82102834"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82022005"],"award-info":[{"award-number":["82022005"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81721001"],"award-info":[{"award-number":["81721001"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","thelancet.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["eBioMedicine"],"published-print":{"date-parts":[[2022,8]]},"DOI":"10.1016\/j.ebiom.2022.104139","type":"journal-article","created":{"date-parts":[[2022,7,8]],"date-time":"2022-07-08T05:56:05Z","timestamp":1657259765000},"page":"104139","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":66,"special_numbering":"C","title":["Inhibition of DYRK1A, via histone modification, promotes cardiomyocyte cell cycle activation and cardiac repair after myocardial infarction"],"prefix":"10.1016","volume":"82","author":[{"given":"Cong","family":"Lan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caiyu","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuang","family":"Qu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nian","family":"Cao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hao","family":"Luo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cheng","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Na","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuanzheng","family":"Xue","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuewei","family":"Xia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chao","family":"Fan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongmei","family":"Ren","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yongjian","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pedro A.","family":"Jose","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zaicheng","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gengze","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0173-5028","authenticated-orcid":false,"given":"Chunyu","family":"Zeng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"12","key":"10.1016\/j.ebiom.2022.104139_bib0001","doi-asserted-by":"crossref","first-page":"1123","DOI":"10.1016\/j.jacc.2013.11.053","article-title":"The global health and economic burden of hospitalizations for heart failure: lessons learned from hospitalized heart failure registries","volume":"63","author":"Ambrosy","year":"2014","journal-title":"J Am Coll Cardiol"},{"issue":"7432","key":"10.1016\/j.ebiom.2022.104139_bib0002","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1038\/nature11682","article-title":"Mammalian heart renewal by pre-existing cardiomyocytes","volume":"493","author":"Senyo","year":"2013","journal-title":"Nature"},{"issue":"6020","key":"10.1016\/j.ebiom.2022.104139_bib0003","doi-asserted-by":"crossref","first-page":"1078","DOI":"10.1126\/science.1200708","article-title":"Transient regenerative potential of the neonatal mouse heart","volume":"331","author":"Porrello","year":"2011","journal-title":"Science"},{"issue":"25","key":"10.1016\/j.ebiom.2022.104139_bib0004","doi-asserted-by":"crossref","first-page":"3017","DOI":"10.1161\/CIRCULATIONAHA.112.107888","article-title":"Hypoxia induces myocardial regeneration in zebrafish","volume":"126","author":"Jopling","year":"2012","journal-title":"Circulation"},{"issue":"2","key":"10.1016\/j.ebiom.2022.104139_bib0005","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1096\/fj.10-165837","article-title":"DYRK family of protein kinases: evolutionary relationships, biochemical properties, and functional roles","volume":"25","author":"Aranda","year":"2011","journal-title":"FASEB J"},{"issue":"8","key":"10.1016\/j.ebiom.2022.104139_bib0006","doi-asserted-by":"crossref","first-page":"1465","DOI":"10.1136\/gutjnl-2018-316128","article-title":"DYRK1A modulates c-MET in pancreatic ductal adenocarcinoma to drive tumour growth","volume":"68","author":"Luna","year":"2019","journal-title":"Gut"},{"issue":"6","key":"10.1016\/j.ebiom.2022.104139_bib0007","doi-asserted-by":"crossref","first-page":"2475","DOI":"10.1172\/JCI63623","article-title":"Inhibition of DYRK1A destabilizes EGFR and reduces EGFR-dependent glioblastoma growth","volume":"123","author":"Pozo","year":"2013","journal-title":"J Clin Invest"},{"issue":"3","key":"10.1016\/j.ebiom.2022.104139_bib0008","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1016\/j.stem.2010.06.021","article-title":"Regulated segregation of kinase Dyrk1A during asymmetric neural stem cell division is critical for EGFR-mediated biased signaling","volume":"7","author":"Ferron","year":"2010","journal-title":"Cell Stem Cell"},{"issue":"4","key":"10.1016\/j.ebiom.2022.104139_bib0009","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1038\/nm.3820","article-title":"A high-throughput chemical screen reveals that harmine-mediated inhibition of DYRK1A increases human pancreatic beta cell replication","volume":"21","author":"Wang","year":"2015","journal-title":"Nat Med"},{"issue":"3","key":"10.1016\/j.ebiom.2022.104139_bib0010","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1093\/cvr\/cvw074","article-title":"Dyrk1a regulates the cardiomyocyte cell cycle via D-cyclin-dependent Rb\/E2F-signalling","volume":"110","author":"Hille","year":"2016","journal-title":"Cardiovasc Res"},{"issue":"14","key":"10.1016\/j.ebiom.2022.104139_bib0011","doi-asserted-by":"crossref","first-page":"1415","DOI":"10.1093\/eurheartj\/ehaa878","article-title":"The role of G protein-coupled receptor kinase 4 in cardiomyocyte injury after myocardial infarction","volume":"42","author":"Li","year":"2021","journal-title":"Eur Heart J"},{"issue":"9","key":"10.1016\/j.ebiom.2022.104139_bib0012","doi-asserted-by":"crossref","first-page":"834","DOI":"10.1161\/CIRCULATIONAHA.116.024307","article-title":"Dedifferentiation, proliferation, and redifferentiation of adult mammalian cardiomyocytes after ischemic injury","volume":"136","author":"Wang","year":"2017","journal-title":"Circulation"},{"key":"10.1016\/j.ebiom.2022.104139_bib0013","first-page":"271","article-title":"Isolation and culture of adult mouse cardiac myocytes","volume":"357","author":"O'Connell","year":"2007","journal-title":"Methods Mol Biol"},{"issue":"1","key":"10.1016\/j.ebiom.2022.104139_bib0014","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1186\/s13045-017-0531-y","article-title":"The stem cell factor SALL4 is an essential transcriptional regulator in mixed lineage leukemia-rearranged leukemogenesis","volume":"10","author":"Yang","year":"2017","journal-title":"J Hematol Oncol"},{"issue":"34","key":"10.1016\/j.ebiom.2022.104139_bib0015","doi-asserted-by":"crossref","first-page":"13839","DOI":"10.1073\/pnas.1313192110","article-title":"Hippo pathway effector Yap promotes cardiac regeneration","volume":"110","author":"Xin","year":"2013","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"4","key":"10.1016\/j.ebiom.2022.104139_bib0016","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1016\/j.devcel.2016.09.005","article-title":"Acetylation of VGLL4 regulates hippo-YAP signaling and postnatal cardiac growth","volume":"39","author":"Lin","year":"2016","journal-title":"Dev Cell"},{"issue":"2","key":"10.1016\/j.ebiom.2022.104139_bib0017","doi-asserted-by":"crossref","first-page":"265","DOI":"10.15252\/emmm.201606602","article-title":"The transcription factor GATA4 promotes myocardial regeneration in neonatal mice","volume":"9","author":"Malek Mohammadi","year":"2017","journal-title":"EMBO Mol Med"},{"issue":"11","key":"10.1016\/j.ebiom.2022.104139_bib0018","doi-asserted-by":"crossref","first-page":"1081","DOI":"10.1161\/CIRCULATIONAHA.115.019357","article-title":"Overexpression of Tbx20 in adult cardiomyocytes promotes proliferation and improves cardiac function after myocardial infarction","volume":"133","author":"Xiang","year":"2016","journal-title":"Circulation"},{"issue":"7662","key":"10.1016\/j.ebiom.2022.104139_bib0019","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1038\/nature22978","article-title":"The extracellular matrix protein agrin promotes heart regeneration in mice","volume":"547","author":"Bassat","year":"2017","journal-title":"Nature"},{"issue":"7811","key":"10.1016\/j.ebiom.2022.104139_bib0020","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1038\/s41586-020-2228-6","article-title":"A calcineurin-Hoxb13 axis regulates growth mode of mammalian cardiomyocytes","volume":"582","author":"Nguyen","year":"2020","journal-title":"Nature"},{"issue":"281","key":"10.1016\/j.ebiom.2022.104139_bib0021","doi-asserted-by":"crossref","first-page":"281ra45","DOI":"10.1126\/scitranslmed.aaa5171","article-title":"Neuregulin stimulation of cardiomyocyte regeneration in mice and human myocardium reveals a therapeutic window","volume":"7","author":"Polizzotti","year":"2015","journal-title":"Sci Transl Med"},{"issue":"7","key":"10.1016\/j.ebiom.2022.104139_bib0022","doi-asserted-by":"crossref","first-page":"1048","DOI":"10.1021\/ar2002304","article-title":"Peptide vectors for the nonviral delivery of nucleic acids","volume":"45","author":"Hoyer","year":"2012","journal-title":"Acc Chemical Res"},{"issue":"5","key":"10.1016\/j.ebiom.2022.104139_bib0023","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1056\/NEJMra1706910","article-title":"Gene therapy","volume":"381","author":"High","year":"2019","journal-title":"N Engl J Med"},{"issue":"1","key":"10.1016\/j.ebiom.2022.104139_bib0024","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1016\/j.cell.2018.02.014","article-title":"Regulation of cell cycle to stimulate adult cardiomyocyte proliferation and cardiac regeneration","volume":"173","author":"Mohamed","year":"2018","journal-title":"Cell"},{"issue":"10","key":"10.1016\/j.ebiom.2022.104139_bib0025","doi-asserted-by":"crossref","first-page":"2677","DOI":"10.1093\/jxb\/ert433","article-title":"Chromatin meets the cell cycle","volume":"65","author":"Raynaud","year":"2014","journal-title":"J Exp Bot"},{"issue":"5","key":"10.1016\/j.ebiom.2022.104139_bib0026","doi-asserted-by":"crossref","first-page":"909","DOI":"10.1016\/j.cmet.2016.04.002","article-title":"Age-dependent pancreatic gene regulation reveals mechanisms governing human \u03b2 cell function","volume":"23","author":"Arda","year":"2016","journal-title":"Cell Metab"},{"issue":"3","key":"10.1016\/j.ebiom.2022.104139_bib0027","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1083\/jcb.201012049","article-title":"Rb and p130 control cell cycle gene silencing to maintain the postmitotic phenotype in cardiac myocytes","volume":"194","author":"Sdek","year":"2011","journal-title":"J Cell Biol"},{"issue":"12","key":"10.1016\/j.ebiom.2022.104139_bib0028","doi-asserted-by":"crossref","first-page":"1220","DOI":"10.1038\/ncb2126","article-title":"MicroRNA-199b targets the nuclear kinase Dyrk1a in an auto-amplification loop promoting calcineurin\/NFAT signalling","volume":"12","author":"da Costa Martins","year":"2010","journal-title":"Nat Cell Biol"},{"issue":"3","key":"10.1016\/j.ebiom.2022.104139_bib0029","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1016\/j.molcel.2014.12.026","article-title":"Chromatin-wide profiling of DYRK1A reveals a role as a gene-specific RNA polymerase II CTD kinase","volume":"57","author":"Di Vona","year":"2015","journal-title":"Mol Cell"},{"issue":"8","key":"10.1016\/j.ebiom.2022.104139_bib0030","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1101\/gad.2034211","article-title":"DYRK1A protein kinase promotes quiescence and senescence through DREAM complex assembly","volume":"25","author":"Litovchick","year":"2011","journal-title":"Genes Dev"},{"issue":"4","key":"10.1016\/j.ebiom.2022.104139_bib0031","doi-asserted-by":"crossref","first-page":"756","DOI":"10.1095\/biolreprod.110.084343","article-title":"WDR82, a key epigenetics-related factor, plays a crucial role in normal early embryonic development in mice","volume":"84","author":"Bi","year":"2011","journal-title":"Biol Reprod"},{"key":"10.1016\/j.ebiom.2022.104139_bib0032","doi-asserted-by":"crossref","DOI":"10.1016\/j.drup.2020.100729","article-title":"The key roles of the lysine acetyltransferases KAT6A and KAT6B in physiology and pathology","volume":"53","author":"Wiesel-Motiuk","year":"2020","journal-title":"Drug Resist Updat"},{"issue":"10","key":"10.1016\/j.ebiom.2022.104139_bib0033","doi-asserted-by":"crossref","DOI":"10.1002\/bies.201800078","article-title":"Histone lysine and genomic targets of histone acetyltransferases in mammals","volume":"40","author":"Voss","year":"2018","journal-title":"BioEssays"},{"key":"10.1016\/j.ebiom.2022.104139_bib0034","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1038\/s41417-020-00223-2","article-title":"BATF3 promotes malignant phenotype of colorectal cancer through the S1PR1\/p-STAT3\/miR-155-3p\/WDR82 axis","volume":"28","author":"Li","year":"2021","journal-title":"Cancer Gene Ther"},{"issue":"3","key":"10.1016\/j.ebiom.2022.104139_bib0035","doi-asserted-by":"crossref","first-page":"638","DOI":"10.1016\/j.cmet.2018.12.005","article-title":"Combined inhibition of DYRK1A, SMAD, and trithorax pathways synergizes to induce robust replication in adult human beta cells","volume":"29","author":"Wang","year":"2019","journal-title":"Cell Metab"},{"key":"10.1016\/j.ebiom.2022.104139_bib0036","doi-asserted-by":"crossref","first-page":"535","DOI":"10.3389\/fphar.2020.00535","article-title":"Harmine ameliorates cognitive impairment by inhibiting NLRP3 inflammasome activation and enhancing the BDNF\/TrkB signaling pathway in STZ-induced diabetic rats","volume":"11","author":"Liu","year":"2020","journal-title":"Front Pharmacol"},{"issue":"7","key":"10.1016\/j.ebiom.2022.104139_bib0037","doi-asserted-by":"crossref","first-page":"1524","DOI":"10.1111\/bph.15378","article-title":"Harmine alleviates atherogenesis by inhibiting disturbed flow-mediated endothelial activation via protein tyrosine phosphatase PTPN14 and YAP","volume":"178","author":"Yang","year":"2021","journal-title":"Br J Pharmacol"},{"issue":"25","key":"10.1016\/j.ebiom.2022.104139_bib0038","doi-asserted-by":"crossref","first-page":"17320","DOI":"10.1074\/jbc.M109.006759","article-title":"DYRK1A is a novel negative regulator of cardiomyocyte hypertrophy","volume":"284","author":"Kuhn","year":"2009","journal-title":"J Biol Chem"},{"issue":"21","key":"10.1016\/j.ebiom.2022.104139_bib0039","doi-asserted-by":"crossref","first-page":"9312","DOI":"10.1021\/jm301034u","article-title":"Selectivity, cocrystal structures, and neuroprotective properties of leucettines, a family of protein kinase inhibitors derived from the marine sponge alkaloid leucettamine B","volume":"55","author":"Tahtouh","year":"2012","journal-title":"J Med Chem"},{"issue":"19","key":"10.1016\/j.ebiom.2022.104139_bib0040","doi-asserted-by":"crossref","DOI":"10.1002\/adhm.201900849","article-title":"In vivo Retargeting of poly(beta aminoester) (OM-PBAE) Nanoparticles is Influenced by Protein Corona","volume":"8","author":"Fornaguera","year":"2019","journal-title":"Adv Healthc Mater"},{"issue":"1","key":"10.1016\/j.ebiom.2022.104139_bib0041","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1186\/s12936-016-1625-7","article-title":"In vitro and in vivo anti-malarial activity of novel harmine-analog heat shock protein 90 inhibitors: a possible partner for artemisinin","volume":"15","author":"Bayih","year":"2016","journal-title":"Malar J"},{"issue":"5","key":"10.1016\/j.ebiom.2022.104139_bib0042","doi-asserted-by":"crossref","first-page":"e13000","DOI":"10.1111\/acel.13000","article-title":"Tau pathology reduction with SM07883, a novel, potent, and selective oral DYRK1A inhibitor: a potential therapeutic for Alzheimer's disease","volume":"18","author":"Melchior","year":"2019","journal-title":"Aging Cell"},{"issue":"6","key":"10.1016\/j.ebiom.2022.104139_bib0043","doi-asserted-by":"crossref","first-page":"2958","DOI":"10.1021\/acs.jmedchem.9b01624","article-title":"Selective DYRK1A inhibitor for the treatment of type 1 diabetes: discovery of 6-azaindole derivative GNF2133","volume":"63","author":"Liu","year":"2020","journal-title":"J Med Chem"}],"container-title":["eBioMedicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2352396422003206?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2352396422003206?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T19:34:18Z","timestamp":1778873658000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2352396422003206"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,8]]},"references-count":43,"alternative-id":["S2352396422003206"],"URL":"https:\/\/doi.org\/10.1016\/j.ebiom.2022.104139","relation":{},"ISSN":["2352-3964"],"issn-type":[{"value":"2352-3964","type":"print"}],"subject":[],"published":{"date-parts":[[2022,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Inhibition of DYRK1A, via histone modification, promotes cardiomyocyte cell cycle activation and cardiac repair after myocardial infarction","name":"articletitle","label":"Article Title"},{"value":"eBioMedicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ebiom.2022.104139","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"104139"}}