{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T11:56:39Z","timestamp":1792842999752,"version":"4.5.0"},"reference-count":61,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,2,13]],"date-time":"2023-02-13T00:00:00Z","timestamp":1676246400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31900505"],"award-info":[{"award-number":["31900505"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32100627"],"award-info":[{"award-number":["32100627"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81902877"],"award-info":[{"award-number":["81902877"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81972245"],"award-info":[{"award-number":["81972245"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82173067"],"award-info":[{"award-number":["82173067"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82272965"],"award-info":[{"award-number":["82272965"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003453","name":"Natural Science Foundation of Guangdong Province","doi-asserted-by":"publisher","award":["2021A1515010134"],"award-info":[{"award-number":["2021A1515010134"]}],"id":[{"id":"10.13039\/501100003453","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003453","name":"Natural Science Foundation of Guangdong Province","doi-asserted-by":"publisher","award":["2021A1515010639"],"award-info":[{"award-number":["2021A1515010639"]}],"id":[{"id":"10.13039\/501100003453","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003453","name":"Natural Science Foundation of Guangdong Province","doi-asserted-by":"publisher","award":["2022A1515012656"],"award-info":[{"award-number":["2022A1515012656"]}],"id":[{"id":"10.13039\/501100003453","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004000","name":"Guangzhou Science and Technology Program key projects","doi-asserted-by":"publisher","award":["202201011004"],"award-info":[{"award-number":["202201011004"]}],"id":[{"id":"10.13039\/501100004000","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012176","name":"Project 211","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100012176","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012232","name":"National Key Clinical Specialty Discipline Construction Program of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100012232","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["thelancet.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["eBioMedicine"],"published-print":{"date-parts":[[2023,4]]},"DOI":"10.1016\/j.ebiom.2023.104496","type":"journal-article","created":{"date-parts":[[2023,2,28]],"date-time":"2023-02-28T18:54:50Z","timestamp":1677610490000},"page":"104496","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":50,"special_numbering":"C","title":["Fasting-mimicking diet synergizes with ferroptosis against quiescent, chemotherapy-resistant cells"],"prefix":"10.1016","volume":"90","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3260-2343","authenticated-orcid":false,"given":"Xiaoxia","family":"Liu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shaoyong","family":"Peng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guannan","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gaopo","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yumo","family":"Xie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dingcheng","family":"Shen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mingxuan","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yaoyi","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaolin","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8357-1615","authenticated-orcid":false,"given":"Huichuan","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meijin","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanxin","family":"Luo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"11","key":"10.1016\/j.ebiom.2023.104496_bib1","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1038\/s41568-018-0061-0","article-title":"Fasting and cancer: molecular mechanisms and clinical application","volume":"18","author":"Nencioni","year":"2018","journal-title":"Nat Rev Cancer"},{"issue":"1","key":"10.1016\/j.ebiom.2023.104496_bib2","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1038\/s43018-019-0007-9","article-title":"Short-term starvation reduces IGF-1 levels to sensitize lung tumors to PD-1 immune checkpoint blockade","volume":"1","author":"Ajona","year":"2020","journal-title":"Nat Cancer"},{"issue":"11","key":"10.1016\/j.ebiom.2023.104496_bib3","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1038\/s41568-019-0198-5","article-title":"A\u00a0framework for examining how diet impacts tumour metabolism","volume":"19","author":"Lien","year":"2019","journal-title":"Nat Rev Cancer"},{"issue":"7817","key":"10.1016\/j.ebiom.2023.104496_bib4","doi-asserted-by":"crossref","first-page":"620","DOI":"10.1038\/s41586-020-2502-7","article-title":"Fasting-mimicking diet and hormone therapy induce breast cancer regression","volume":"583","author":"Caffa","year":"2020","journal-title":"Nature"},{"issue":"124","key":"10.1016\/j.ebiom.2023.104496_bib5","doi-asserted-by":"crossref","first-page":"124ra27","DOI":"10.1126\/scitranslmed.3003293","article-title":"Fasting cycles retard growth of tumors and sensitize a range of cancer cell types to chemotherapy","volume":"4","author":"Lee","year":"2012","journal-title":"Sci Transl Med"},{"issue":"24","key":"10.1016\/j.ebiom.2023.104496_bib6","doi-asserted-by":"crossref","first-page":"8215","DOI":"10.1073\/pnas.0708100105","article-title":"Starvation-dependent differential stress resistance protects normal but not cancer cells against high-dose chemotherapy","volume":"105","author":"Raffaghello","year":"2008","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"1","key":"10.1016\/j.ebiom.2023.104496_bib7","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/j.ccell.2016.05.016","article-title":"Caloric restriction mimetics enhance anticancer immunosurveillance","volume":"30","author":"Pietrocola","year":"2016","journal-title":"Cancer Cell"},{"key":"10.1016\/j.ebiom.2023.104496_bib8","doi-asserted-by":"crossref","first-page":"1402","DOI":"10.3389\/fimmu.2019.01402","article-title":"Targeting glucose metabolism to enhance immunotherapy: emerging evidence on intermittent fasting and calorie restriction mimetics","volume":"10","author":"Turbitt","year":"2019","journal-title":"Front Immunol"},{"issue":"11","key":"10.1016\/j.ebiom.2023.104496_bib9","doi-asserted-by":"crossref","first-page":"2317","DOI":"10.1016\/j.molcel.2021.03.037","article-title":"Energy status dictates PD-L1 protein abundance and anti-tumor immunity to enable checkpoint blockade","volume":"81","author":"Dai","year":"2021","journal-title":"Mol Cell"},{"issue":"1","key":"10.1016\/j.ebiom.2023.104496_bib10","first-page":"7","article-title":"Cancer statistics, 2021","volume":"71","author":"Siegel","year":"2021","journal-title":"CA A Cancer J Clin"},{"issue":"1","key":"10.1016\/j.ebiom.2023.104496_bib11","doi-asserted-by":"crossref","first-page":"1248","DOI":"10.1038\/s41467-022-28913-5","article-title":"Fusobacterium nucleatum reduces METTL3-mediated m(6)A modification and contributes to colorectal cancer metastasis","volume":"13","author":"Chen","year":"2022","journal-title":"Nat Commun"},{"issue":"6","key":"10.1016\/j.ebiom.2023.104496_bib12","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1093\/gastro\/goab048","article-title":"Clinical characteristics and survival analysis of colorectal cancer in China: a retrospective cohort study with 13,328 patients from southern China","volume":"9","author":"Fang","year":"2021","journal-title":"Gastroenterol Rep (Oxf)"},{"issue":"8","key":"10.1016\/j.ebiom.2023.104496_bib13","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1038\/s41568-022-00485-y","article-title":"Developing dietary interventions as therapy for cancer","volume":"22","author":"Taylor","year":"2022","journal-title":"Nat Rev Cancer"},{"issue":"3","key":"10.1016\/j.ebiom.2023.104496_bib14","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1021\/ac051437y","article-title":"XCMS: processing mass spectrometry data for metabolite profiling using nonlinear peak alignment, matching, and identification","volume":"78","author":"Smith","year":"2006","journal-title":"Anal Chem"},{"issue":"1","key":"10.1016\/j.ebiom.2023.104496_bib15","doi-asserted-by":"crossref","first-page":"1869","DOI":"10.1038\/s41467-020-15795-8","article-title":"Fasting inhibits aerobic glycolysis and proliferation in colorectal cancer via the Fdft1-mediated AKT\/mTOR\/HIF1\u03b1 pathway suppression","volume":"11","author":"Weng","year":"2020","journal-title":"Nat Commun"},{"issue":"1","key":"10.1016\/j.ebiom.2023.104496_bib16","doi-asserted-by":"crossref","first-page":"2332","DOI":"10.1038\/s41467-020-16243-3","article-title":"Synergistic effect of fasting-mimicking diet and vitamin C against KRAS mutated cancers","volume":"11","author":"Di Tano","year":"2020","journal-title":"Nat Commun"},{"issue":"16","key":"10.1016\/j.ebiom.2023.104496_bib17","doi-asserted-by":"crossref","first-page":"2938","DOI":"10.1200\/JCO.2000.18.16.2938","article-title":"Leucovorin and fluorouracil with or without oxaliplatin as first-line treatment in advanced colorectal cancer","volume":"18","author":"de Gramont","year":"2000","journal-title":"J\u00a0Clin Oncol"},{"issue":"21","key":"10.1016\/j.ebiom.2023.104496_bib18","doi-asserted-by":"crossref","first-page":"18545","DOI":"10.18632\/oncotarget.4186","article-title":"Fasting cycles potentiate the efficacy of gemcitabine treatment in in\u00a0vitro and in\u00a0vivo pancreatic cancer models","volume":"6","author":"D'Aronzo","year":"2015","journal-title":"Oncotarget"},{"issue":"10","key":"10.1016\/j.ebiom.2023.104496_bib19","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1038\/s41389-021-00355-6","article-title":"Single-cell RNA sequencing reveals cell heterogeneity and transcriptome profile of breast cancer lymph node metastasis","volume":"10","author":"Xu","year":"2021","journal-title":"Oncogenesis"},{"issue":"10","key":"10.1016\/j.ebiom.2023.104496_bib20","doi-asserted-by":"crossref","first-page":"1694","DOI":"10.1016\/j.cell.2022.03.033","article-title":"Quiescent cancer cells resist T cell attack by forming an immunosuppressive niche","volume":"185","author":"Baldominos","year":"2022","journal-title":"Cell"},{"issue":"8","key":"10.1016\/j.ebiom.2023.104496_bib21","doi-asserted-by":"crossref","first-page":"1946","DOI":"10.1016\/j.celrep.2017.02.001","article-title":"Chemotherapy-induced Ca(2+) release stimulates breast cancer stem cell enrichment","volume":"18","author":"Lu","year":"2017","journal-title":"Cell Rep"},{"issue":"8","key":"10.1016\/j.ebiom.2023.104496_bib22","doi-asserted-by":"crossref","first-page":"3173","DOI":"10.1111\/cas.14969","article-title":"Mitotic checkpoint regulator RAE1 promotes tumor growth in colorectal cancer","volume":"112","author":"Kobayashi","year":"2021","journal-title":"Cancer Sci"},{"issue":"6","key":"10.1016\/j.ebiom.2023.104496_bib23","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1016\/j.ccell.2018.10.014","article-title":"KDM5 histone demethylase activity links cellular transcriptomic heterogeneity to therapeutic resistance","volume":"34","author":"Hinohara","year":"2018","journal-title":"Cancer Cell"},{"issue":"16","key":"10.1016\/j.ebiom.2023.104496_bib24","doi-asserted-by":"crossref","first-page":"3420","DOI":"10.1016\/j.ejca.2013.06.001","article-title":"Nuclear orphan receptor NR4A2 confers chemoresistance and predicts unfavorable prognosis of colorectal carcinoma patients who received postoperative chemotherapy","volume":"49","author":"Han","year":"2013","journal-title":"Eur J Cancer"},{"issue":"7631","key":"10.1016\/j.ebiom.2023.104496_bib25","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1038\/nature20578","article-title":"Inhibition of mTOR induces a paused pluripotent state","volume":"540","author":"Bulut-Karslioglu","year":"2016","journal-title":"Nature"},{"issue":"1","key":"10.1016\/j.ebiom.2023.104496_bib26","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1016\/j.cell.2020.11.018","article-title":"Colorectal cancer cells enter a diapause-like DTP state to survive chemotherapy","volume":"184","author":"Rehman","year":"2021","journal-title":"Cell"},{"issue":"1","key":"10.1016\/j.ebiom.2023.104496_bib27","doi-asserted-by":"crossref","first-page":"3083","DOI":"10.1038\/s41467-020-16138-3","article-title":"Fasting mimicking diet as an adjunct to neoadjuvant chemotherapy for breast cancer in the multicentre randomized phase 2 DIRECT trial","volume":"11","author":"de Groot","year":"2020","journal-title":"Nat Commun"},{"issue":"5","key":"10.1016\/j.ebiom.2023.104496_bib28","doi-asserted-by":"crossref","first-page":"650","DOI":"10.1016\/j.stem.2017.10.001","article-title":"TGF-\u03b2-Induced quiescence mediates chemoresistance of tumor-propagating cells in squamous cell carcinoma","volume":"21","author":"Brown","year":"2017","journal-title":"Cell Stem Cell"},{"issue":"7679","key":"10.1016\/j.ebiom.2023.104496_bib29","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1038\/nature24297","article-title":"Drug-tolerant persister cancer cells are vulnerable to GPX4 inhibition","volume":"551","author":"Hangauer","year":"2017","journal-title":"Nature"},{"issue":"5","key":"10.1016\/j.ebiom.2023.104496_bib30","doi-asserted-by":"crossref","first-page":"1060","DOI":"10.1016\/j.cell.2012.03.042","article-title":"Ferroptosis: an iron-dependent form of nonapoptotic cell death","volume":"149","author":"Dixon","year":"2012","journal-title":"Cell"},{"key":"10.1016\/j.ebiom.2023.104496_bib31","article-title":"Heat shock proteins and ferroptosis","volume":"10","author":"Liu","year":"2022","journal-title":"Front Cell Dev Biol"},{"issue":"1","key":"10.1016\/j.ebiom.2023.104496_bib32","doi-asserted-by":"crossref","first-page":"2508","DOI":"10.1038\/s41467-020-16126-7","article-title":"2,4-dienoyl-CoA reductase regulates lipid homeostasis in treatment-resistant prostate cancer","volume":"11","author":"Blomme","year":"2020","journal-title":"Nat Commun"},{"key":"10.1016\/j.ebiom.2023.104496_bib33","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1016\/j.freeradbiomed.2021.09.008","article-title":"Endoplasmic reticulum stress-mediated autophagy activation is involved in cadmium-induced ferroptosis of renal tubular epithelial cells","volume":"175","author":"Zhao","year":"2021","journal-title":"Free Radic Biol Med"},{"issue":"4","key":"10.1016\/j.ebiom.2023.104496_bib34","doi-asserted-by":"crossref","first-page":"728","DOI":"10.1016\/j.cell.2011.10.026","article-title":"Autophagy: renovation of cells and tissues","volume":"147","author":"Mizushima","year":"2011","journal-title":"Cell"},{"issue":"1","key":"10.1016\/j.ebiom.2023.104496_bib35","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1038\/s41467-020-14384-z","article-title":"Fasting-induced FGF21 signaling activates hepatic autophagy and lipid degradation via JMJD3 histone demethylase","volume":"11","author":"Byun","year":"2020","journal-title":"Nat Commun"},{"key":"10.1016\/j.ebiom.2023.104496_bib36","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/j.semcancer.2019.03.002","article-title":"Ferroptosis is a type of autophagy-dependent cell death","volume":"66","author":"Zhou","year":"2020","journal-title":"Semin Cancer Biol"},{"issue":"8","key":"10.1016\/j.ebiom.2023.104496_bib37","doi-asserted-by":"crossref","first-page":"1425","DOI":"10.1080\/15548627.2016.1187366","article-title":"Autophagy promotes ferroptosis by degradation of ferritin","volume":"12","author":"Hou","year":"2016","journal-title":"Autophagy"},{"issue":"11","key":"10.1016\/j.ebiom.2023.104496_bib38","doi-asserted-by":"crossref","first-page":"3592","DOI":"10.1080\/15548627.2021.1885203","article-title":"Cannabidiol inhibits human glioma by induction of lethal mitophagy through activating TRPV4","volume":"17","author":"Huang","year":"2021","journal-title":"Autophagy"},{"issue":"7800","key":"10.1016\/j.ebiom.2023.104496_bib39","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1038\/s41586-020-2124-0","article-title":"Dietary modifications for enhanced cancer therapy","volume":"579","author":"Kanarek","year":"2020","journal-title":"Nature"},{"issue":"1","key":"10.1016\/j.ebiom.2023.104496_bib40","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1080\/01902148.2020.1840667","article-title":"Ketogenic diet induces autophagy to alleviate bleomycin-induced pulmonary fibrosis in murine models","volume":"47","author":"Mu","year":"2021","journal-title":"Exp Lung Res"},{"issue":"4","key":"10.1016\/j.ebiom.2023.104496_bib41","doi-asserted-by":"crossref","first-page":"1564","DOI":"10.1158\/0008-5472.CAN-09-3228","article-title":"Reduced levels of IGF-I mediate differential protection of normal and cancer cells in response to fasting and improve chemotherapeutic index","volume":"70","author":"Lee","year":"2010","journal-title":"Cancer Res"},{"issue":"1","key":"10.1016\/j.ebiom.2023.104496_bib42","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1016\/j.ccell.2016.06.005","article-title":"Fasting-mimicking diet reduces HO-1 to promote T cell-mediated tumor cytotoxicity","volume":"30","author":"Di Biase","year":"2016","journal-title":"Cancer Cell"},{"issue":"1","key":"10.1016\/j.ebiom.2023.104496_bib43","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1158\/2159-8290.CD-21-0030","article-title":"Fasting-mimicking diet is safe and reshapes metabolism and antitumor immunity in patients with cancer","volume":"12","author":"Vernieri","year":"2022","journal-title":"Cancer Discov"},{"issue":"3","key":"10.1016\/j.ebiom.2023.104496_bib44","doi-asserted-by":"crossref","DOI":"10.1126\/sciadv.abh2635","article-title":"Fasting improves therapeutic response in hepatocellular carcinoma through p53-dependent metabolic synergism","volume":"8","author":"Krstic","year":"2022","journal-title":"Sci Adv"},{"issue":"5","key":"10.1016\/j.ebiom.2023.104496_bib45","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1001\/jamainternmed.2015.59","article-title":"Vegetarian dietary patterns and the risk of colorectal cancers","volume":"175","author":"Orlich","year":"2015","journal-title":"JAMA Intern Med"},{"issue":"3","key":"10.1016\/j.ebiom.2023.104496_bib46","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1001\/jamaoncol.2017.4844","article-title":"Association of dietary inflammatory potential with colorectal cancer risk in men and women","volume":"4","author":"Tabung","year":"2018","journal-title":"JAMA Oncol"},{"issue":"11","key":"10.1016\/j.ebiom.2023.104496_bib47","first-page":"2759","article-title":"Inhibition of chemically induced mammary and colon tumor promotion by caloric restriction in rats fed increased dietary fat","volume":"47","author":"Klurfeld","year":"1987","journal-title":"Cancer Res"},{"issue":"1","key":"10.1016\/j.ebiom.2023.104496_bib48","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/j.stem.2018.12.009","article-title":"Cancer stem cells: the architects of the tumor ecosystem","volume":"24","author":"Prager","year":"2019","journal-title":"Cell Stem Cell"},{"key":"10.1016\/j.ebiom.2023.104496_bib49","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1186\/s12935-017-0382-1","article-title":"TNF-\u03b1 sensitizes chemotherapy and radiotherapy against breast cancer cells","volume":"17","author":"Wu","year":"2017","journal-title":"Cancer Cell Int"},{"issue":"4","key":"10.1016\/j.ebiom.2023.104496_bib50","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1002\/bit.21985","article-title":"Single-cell analysis demonstrates how nutrient deprivation creates apoptotic and quiescent cell populations in tumor cylindroids","volume":"101","author":"Kim","year":"2008","journal-title":"Biotechnol Bioeng"},{"key":"10.1016\/j.ebiom.2023.104496_bib51","doi-asserted-by":"crossref","first-page":"173","DOI":"10.3389\/fonc.2018.00173","article-title":"Microenvironment-driven dynamic heterogeneity and phenotypic plasticity as a mechanism of melanoma therapy resistance","volume":"8","author":"Ahmed","year":"2018","journal-title":"Front Oncol"},{"issue":"488","key":"10.1016\/j.ebiom.2023.104496_bib52","doi-asserted-by":"crossref","DOI":"10.1126\/scitranslmed.aav0936","article-title":"Resistance to neoadjuvant chemotherapy in triple-negative breast cancer mediated by a reversible drug-tolerant state","volume":"11","author":"Echeverria","year":"2019","journal-title":"Sci Transl Med"},{"issue":"6","key":"10.1016\/j.ebiom.2023.104496_bib53","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1016\/j.ccell.2016.11.002","article-title":"Characterization of rare, dormant, and therapy-resistant cells in acute lymphoblastic leukemia","volume":"30","author":"Ebinger","year":"2016","journal-title":"Cancer Cell"},{"key":"10.1016\/j.ebiom.2023.104496_bib54","doi-asserted-by":"crossref","first-page":"8983","DOI":"10.1038\/ncomms9983","article-title":"Osteoclasts control reactivation of dormant myeloma cells by remodelling the endosteal niche","volume":"6","author":"Lawson","year":"2015","journal-title":"Nat Commun"},{"issue":"3","key":"10.1016\/j.ebiom.2023.104496_bib55","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1084\/jem.20121229","article-title":"Cytotoxic T cells induce proliferation of chronic myeloid leukemia stem cells by secreting interferon-\u03b3","volume":"210","author":"Sch\u00fcrch","year":"2013","journal-title":"J\u00a0Exp Med"},{"issue":"2","key":"10.1016\/j.ebiom.2023.104496_bib56","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1016\/j.tips.2018.12.004","article-title":"Targeting cancer cell dormancy","volume":"40","author":"Recasens","year":"2019","journal-title":"Trends Pharmacol Sci"},{"issue":"7","key":"10.1016\/j.ebiom.2023.104496_bib57","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1038\/s41568-020-0263-0","article-title":"The dormant cancer cell life cycle","volume":"20","author":"Phan","year":"2020","journal-title":"Nat Rev Cancer"},{"issue":"2","key":"10.1016\/j.ebiom.2023.104496_bib58","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1038\/s41422-020-00441-1","article-title":"Ferroptosis: molecular mechanisms and health implications","volume":"31","author":"Tang","year":"2021","journal-title":"Cell Res"},{"issue":"14","key":"10.1016\/j.ebiom.2023.104496_bib59","doi-asserted-by":"crossref","first-page":"2401","DOI":"10.1016\/j.cell.2022.06.003","article-title":"Ferroptosis turns 10: emerging mechanisms, physiological functions, and therapeutic applications","volume":"185","author":"Stockwell","year":"2022","journal-title":"Cell"},{"issue":"9","key":"10.1016\/j.ebiom.2023.104496_bib60","doi-asserted-by":"crossref","first-page":"1021","DOI":"10.1038\/cr.2016.95","article-title":"Ferroptosis is an autophagic cell death process","volume":"26","author":"Gao","year":"2016","journal-title":"Cell Res"},{"issue":"15","key":"10.1016\/j.ebiom.2023.104496_bib61","doi-asserted-by":"crossref","DOI":"10.3390\/nu14153120","article-title":"A\u00a0Comparison of the impact of restrictive diets on the gastrointestinal tract of mice","volume":"14","author":"Gregor","year":"2022","journal-title":"Nutrients"}],"container-title":["eBioMedicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2352396423000610?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2352396423000610?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,6]],"date-time":"2025-11-06T19:24:00Z","timestamp":1762457040000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2352396423000610"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,4]]},"references-count":61,"alternative-id":["S2352396423000610"],"URL":"https:\/\/doi.org\/10.1016\/j.ebiom.2023.104496","relation":{},"ISSN":["2352-3964"],"issn-type":[{"value":"2352-3964","type":"print"}],"subject":[],"published":{"date-parts":[[2023,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Fasting-mimicking diet synergizes with ferroptosis against quiescent, chemotherapy-resistant cells","name":"articletitle","label":"Article Title"},{"value":"eBioMedicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ebiom.2023.104496","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 The Author(s). Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"104496"}}