{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,31]],"date-time":"2026-10-31T05:54:08Z","timestamp":1793426048373,"version":"4.5.0"},"reference-count":77,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T00:00:00Z","timestamp":1682899200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T00:00:00Z","timestamp":1682899200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,3,17]],"date-time":"2023-03-17T00:00:00Z","timestamp":1679011200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100010269","name":"Wellcome Trust","doi-asserted-by":"publisher","award":["217065\/Z\/19\/Z"],"award-info":[{"award-number":["217065\/Z\/19\/Z"]}],"id":[{"id":"10.13039\/100010269","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100012095","name":"Scottish Government","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100012095","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000867","name":"Robert Wood Johnson Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000867","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100001370","name":"Wayne and Gladys Valley Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100001370","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006132","name":"Office of Science","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006132","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000272","name":"National Institute for Health and Care Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000272","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100011025","name":"Government of Western Australia","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100011025","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100015539","name":"Australian Government","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100015539","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012617","name":"Moorfields Eye Hospital NHS Foundation Trust","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100012617","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100015846","name":"Llywodraeth Cymru","doi-asserted-by":"publisher","award":["24WG201"],"award-info":[{"award-number":["24WG201"]}],"id":[{"id":"10.13039\/100015846","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100020692","name":"Memphis Research Consortium","doi-asserted-by":"publisher","award":["076467\/Z\/05\/Z"],"award-info":[{"award-number":["076467\/Z\/05\/Z"]}],"id":[{"id":"10.13039\/100020692","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100020692","name":"Memphis Research Consortium","doi-asserted-by":"publisher","award":["WT088806"],"award-info":[{"award-number":["WT088806"]}],"id":[{"id":"10.13039\/100020692","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000265","name":"Medical Research Council","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000265","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["5011549"],"award-info":[{"award-number":["5011549"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000274","name":"British Heart Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000274","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000276","name":"Department of Health and Social Care","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000276","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000361","name":"Diabetes UK","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000361","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000615","name":"Fight for Sight UK","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000615","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001828","name":"Erasmus Universiteit Rotterdam","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001828","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003246","name":"Nederlandse Organisatie voor Wetenschappelijk Onderzoek","doi-asserted-by":"publisher","award":["91815655"],"award-info":[{"award-number":["91815655"]}],"id":[{"id":"10.13039\/501100003246","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004186","name":"Northwest Regional Development Agency","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004186","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000053","name":"National Eye Institute","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000053","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000863","name":"Ellison Medical Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000863","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000025","name":"National Institute of Mental Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000025","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["thelancet.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["eBioMedicine"],"published-print":{"date-parts":[[2023,5]]},"DOI":"10.1016\/j.ebiom.2023.104551","type":"journal-article","created":{"date-parts":[[2023,4,11]],"date-time":"2023-04-11T04:59:10Z","timestamp":1681189150000},"page":"104551","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":33,"special_numbering":"C","title":["A new polygenic score for refractive error improves detection of children at risk of high myopia but not the prediction of those at risk of myopic macular degeneration"],"prefix":"10.1016","volume":"91","author":[{"given":"Rosie","family":"Clark","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samantha Sze-Yee","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ran","family":"Du","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yining","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sander C.M.","family":"Kneepkens","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jason","family":"Charng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael L.","family":"Hunter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chen","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.Willem L.","family":"Tideman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ronald B.","family":"Melles","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caroline C.W.","family":"Klaver","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David A.","family":"Mackey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cathy","family":"Williams","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H\u00e9l\u00e8ne","family":"Choquet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyoko","family":"Ohno-Matsui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5164-340X","authenticated-orcid":false,"given":"Jeremy A.","family":"Guggenheim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joan E.","family":"Bailey-Wilson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul N.","family":"Baird","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Veluchamy A.","family":"Barathi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ginevra","family":"Biino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathryn P.","family":"Burdon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harry","family":"Campbell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li Jia","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ching-Yu","family":"Cheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emily Y.","family":"Chew","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jamie E.","family":"Craig","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Margaret M.","family":"Deangelis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C\u00e9cile","family":"Delcourt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaohu","family":"Ding","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiao","family":"Fan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maurizio","family":"Fossarello","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul J.","family":"Foster","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Puya","family":"Gharahkhani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeremy A.","family":"Guggenheim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaobo","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annechien E.G.","family":"Haarman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toomas","family":"Haller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher J.","family":"Hammond","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xikun","family":"Han","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caroline","family":"Hayward","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mingguang","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alex W.","family":"Hewitt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Quan","family":"Hoang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pirro G.","family":"Hysi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adriana I.","family":"Iglesias","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert P.","family":"Igo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sudha K.","family":"Iyengar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jost B.","family":"Jonas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mika","family":"K\u00e4h\u00f6nen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jaakko","family":"Kaprio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anthony P.","family":"Khawaja","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barbara E.","family":"Klein","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan H.","family":"Lass","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kris","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Terho","family":"Lehtim\u00e4ki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deyana","family":"Lewis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qing","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shi-Ming","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leo-Pekka","family":"Lyytik\u00e4inen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stuart","family":"MacGregor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David A.","family":"Mackey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicholas G.","family":"Martin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akira","family":"Meguro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andres","family":"Metspalu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Candace","family":"Middlebrooks","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masahiro","family":"Miyake","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nobuhisa","family":"Mizuki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anthony","family":"Musolf","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefan","family":"Nickels","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Konrad","family":"Oexle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chi Pui","family":"Pang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olavi","family":"P\u00e4rssinen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew D.","family":"Paterson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Norbert","family":"Pfeiffer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ozren","family":"Polasek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jugnoo S.","family":"Rahi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olli","family":"Raitakari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Igor","family":"Rudan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Srujana","family":"Sahebjada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seang-Mei","family":"Saw","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claire L.","family":"Simpson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dwight","family":"Stambolian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E-Shyong","family":"Tai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Milly S.","family":"Tedja","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. Willem L.","family":"Tideman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akitaka","family":"Tsujikawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cornelia M.","family":"van Duijn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Virginie J.M.","family":"Verhoeven","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Veronique","family":"Vitart","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ningli","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ya Xing","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juho","family":"Wedenoja","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen Bin","family":"Wei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cathy","family":"Williams","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katie M.","family":"Williams","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James F.","family":"Wilson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Wojciechowski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jason C.S.","family":"Yam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenji","family":"Yamashiro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maurice K.H.","family":"Yap","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seyhan","family":"Yazar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shea Ping","family":"Yip","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Terri L.","family":"Young","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiangtian","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naomi","family":"Allen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tariq","family":"Aslam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Denize","family":"Atan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah","family":"Barman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jenny","family":"Barrett","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"Bishop","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Graeme","family":"Black","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catey","family":"Bunce","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roxana","family":"Carare","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Usha","family":"Chakravarthy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michelle","family":"Chan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sharon","family":"Chua","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valentina","family":"Cipriani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander","family":"Day","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Parul","family":"Desai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bal","family":"Dhillon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew","family":"Dick","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander","family":"Doney","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cathy","family":"Egan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah","family":"Ennis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"Foster","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcus","family":"Fruttiger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Gallacher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Garway-Heath","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jane","family":"Gibson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dan","family":"Gore","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeremy","family":"Guggenheim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chris","family":"Hammond","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alison","family":"Hardcastle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simon","family":"Harding","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruth","family":"Hogg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pirro","family":"Hysi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pearse A.","family":"Keane","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peng Tee","family":"Khaw","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anthony","family":"Khawaja","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gerassimos","family":"Lascaratos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Littlejohns","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew","family":"Lotery","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Phil","family":"Luthert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tom","family":"MacGillivray","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah","family":"Mackie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernadette","family":"McGuinness","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gareth","family":"McKay","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"McKibbin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danny","family":"Mitry","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tony","family":"Moore","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James","family":"Morgan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zaynah","family":"Muthy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eoin","family":"O'Sullivan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chris","family":"Owen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Praveen","family":"Patel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Euan","family":"Paterson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tunde","family":"Peto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Axel","family":"Petzold","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nikolas","family":"Pontikos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jugnoo","family":"Rahi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alicja","family":"Rudnicka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jay","family":"Self","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Panagiotis","family":"Sergouniotis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sobha","family":"Sivaprasad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Steel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Irene","family":"Stratton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicholas","family":"Strouthidis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cathie","family":"Sudlow","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robyn","family":"Tapp","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caroline","family":"Thaung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dhanes","family":"Thomas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emanuele","family":"Trucco","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adnan","family":"Tufail","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen","family":"Vernon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ananth","family":"Viswanathan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Veronique","family":"Vitart","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cathy","family":"Williams","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katie","family":"Williams","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jayne","family":"Woodside","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Max","family":"Yates","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer","family":"Yip","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yalin","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"9827","key":"10.1016\/j.ebiom.2023.104551_bib1","doi-asserted-by":"crossref","first-page":"1739","DOI":"10.1016\/S0140-6736(12)60272-4","article-title":"Myopia","volume":"379","author":"Morgan","year":"2012","journal-title":"Lancet"},{"issue":"1","key":"10.1016\/j.ebiom.2023.104551_bib2","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1038\/s41572-020-00231-4","article-title":"Myopia","volume":"6","author":"Baird","year":"2020","journal-title":"Nat Rev Dis Primers"},{"issue":"3","key":"10.1016\/j.ebiom.2023.104551_bib3","doi-asserted-by":"crossref","first-page":"M1","DOI":"10.1167\/iovs.18-25980","article-title":"IMI - myopia control reports overview and introduction","volume":"60","author":"Wolffsohn","year":"2019","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"6","key":"10.1016\/j.ebiom.2023.104551_bib4","first-page":"340.e1","article-title":"Association between refractive errors and horizontal strabismus: the Korea National Health and Nutrition Examination Survey","volume":"25","author":"Lee","year":"2021","journal-title":"J\u00a0AAPOS"},{"key":"10.1016\/j.ebiom.2023.104551_bib5","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1016\/j.ajo.2019.10.013","article-title":"Refractive errors and amblyopia among children screened by the UCLA preschool vision program in Los Angeles county","volume":"210","author":"Margines","year":"2020","journal-title":"Am J Ophthalmol"},{"issue":"5","key":"10.1016\/j.ebiom.2023.104551_bib6","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1167\/iovs.62.5.5","article-title":"IMI pathologic myopia","volume":"62","author":"Ohno-Matsui","year":"2021","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"12","key":"10.1016\/j.ebiom.2023.104551_bib7","doi-asserted-by":"crossref","first-page":"1748","DOI":"10.1136\/bjophthalmol-2019-315298","article-title":"Prevalence of myopic macular degeneration worldwide: a systematic review and meta-analysis","volume":"104","author":"Zou","year":"2020","journal-title":"Br J Ophthalmol"},{"issue":"7","key":"10.1016\/j.ebiom.2023.104551_bib8","doi-asserted-by":"crossref","first-page":"855","DOI":"10.1136\/bjophthalmol-2017-311266","article-title":"Global prevalence of visual impairment associated with myopic macular degeneration and temporal trends from 2000 through 2050: systematic review, meta-analysis and modelling","volume":"102","author":"Fricke","year":"2018","journal-title":"Br J Ophthalmol"},{"issue":"3","key":"10.1016\/j.ebiom.2023.104551_bib9","first-page":"198","article-title":"The first \"classical\" twin study? Analysis of refractive error using monozygotic and dizygotic twins published in 1922","volume":"8","author":"Liew","year":"2005","journal-title":"Twin Res Hum Genet"},{"key":"10.1016\/j.ebiom.2023.104551_bib10","series-title":"Refraction and its components in twins. Med Res Counc (G.B.) Special Report Serial No. 303","author":"Sorsby","year":"1962"},{"issue":"3","key":"10.1016\/j.ebiom.2023.104551_bib11","doi-asserted-by":"crossref","first-page":"M89","DOI":"10.1167\/iovs.18-25965","article-title":"IMI - myopia genetics report","volume":"60","author":"Tedja","year":"2019","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"5","key":"10.1016\/j.ebiom.2023.104551_bib12","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1167\/iovs.62.5.7","article-title":"IMI 2021 yearly digest","volume":"62","author":"Jong","year":"2021","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.ebiom.2023.104551_bib13","doi-asserted-by":"crossref","DOI":"10.1016\/j.exer.2019.107778","article-title":"An overview of myopia genetics","volume":"188","author":"Cai","year":"2019","journal-title":"Exp Eye Res"},{"issue":"2","key":"10.1016\/j.ebiom.2023.104551_bib14","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pgen.1003299","article-title":"Genome-wide analysis points to roles for extracellular matrix remodeling, the visual cycle, and neuronal development in myopia","volume":"9","author":"Kiefer","year":"2013","journal-title":"PLoS Genet"},{"issue":"3","key":"10.1016\/j.ebiom.2023.104551_bib15","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1038\/ng.2554","article-title":"Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia","volume":"45","author":"Verhoeven","year":"2013","journal-title":"Nat Genet"},{"key":"10.1016\/j.ebiom.2023.104551_bib16","doi-asserted-by":"crossref","first-page":"834","DOI":"10.1038\/s41588-018-0127-7","article-title":"Genome-wide association meta-analysis highlights light-induced signaling as a driver for refractive error","volume":"50","author":"Tedja","year":"2018","journal-title":"Nat Genet"},{"issue":"4","key":"10.1016\/j.ebiom.2023.104551_bib17","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1038\/s41588-020-0599-0","article-title":"Meta-analysis of 542,934 subjects of European ancestry identifies new genes and mechanisms predisposing to refractive error and myopia","volume":"52","author":"Hysi","year":"2020","journal-title":"Nat Genet"},{"issue":"6","key":"10.1016\/j.ebiom.2023.104551_bib18","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1001\/jamaophthalmol.2021.0497","article-title":"Evaluation of shared genetic susceptibility to high and low myopia and hyperopia","volume":"139","author":"Tideman","year":"2021","journal-title":"JAMA Ophthalmol"},{"issue":"11","key":"10.1016\/j.ebiom.2023.104551_bib19","doi-asserted-by":"crossref","first-page":"1142","DOI":"10.1001\/jama.2015.10803","article-title":"Effect of time spent outdoors at school on the development of myopia among children in China: a randomized clinical trial","volume":"314","author":"He","year":"2015","journal-title":"JAMA"},{"key":"10.1016\/j.ebiom.2023.104551_bib20","article-title":"Education and myopia: assessing the direction of causality by mendelian randomisation","volume":"361","author":"Mountjoy","year":"2018","journal-title":"BMJ"},{"key":"10.1016\/j.ebiom.2023.104551_bib21","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1038\/s42003-019-0387-5","article-title":"Quantile regression analysis reveals widespread evidence for gene-environment or gene-gene interactions in myopia development","volume":"2","author":"Pozarickij","year":"2019","journal-title":"Commun Biol"},{"issue":"2","key":"10.1016\/j.ebiom.2023.104551_bib22","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1167\/iovs.61.2.41","article-title":"Evidence that emmetropization buffers against both genetic and environmental risk factors for myopia","volume":"61","author":"Pozarickij","year":"2020","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"12","key":"10.1016\/j.ebiom.2023.104551_bib23","doi-asserted-by":"crossref","first-page":"4052","DOI":"10.1167\/iovs.19-27921","article-title":"Expanding the phenotypic and genotypic landscape of nonsyndromic high myopia: a cross-sectional study in 731 Chinese patients","volume":"60","author":"Cai","year":"2019","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"3","key":"10.1016\/j.ebiom.2023.104551_bib24","doi-asserted-by":"crossref","first-page":"M106","DOI":"10.1167\/iovs.18-25958","article-title":"IMI - interventions for controlling myopia onset and progression report","volume":"60","author":"Wildsoet","year":"2019","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"1","key":"10.1016\/j.ebiom.2023.104551_bib25","article-title":"Interventions to slow progression of myopia in children","volume":"1","author":"Walline","year":"2020","journal-title":"Cochrane Database Syst Rev"},{"issue":"5","key":"10.1016\/j.ebiom.2023.104551_bib26","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1167\/iovs.62.5.6","article-title":"IMI prevention of myopia and its progression","volume":"62","author":"Jonas","year":"2021","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"5","key":"10.1016\/j.ebiom.2023.104551_bib27","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1167\/iovs.62.5.3","article-title":"IMI risk factors for myopia","volume":"62","author":"Morgan","year":"2021","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.ebiom.2023.104551_bib28","doi-asserted-by":"crossref","first-page":"5836","DOI":"10.1167\/iovs.10-5592","article-title":"Validating the accuracy of a model to predict the onset of myopia in children","volume":"52","author":"Zhang","year":"2011","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"6","key":"10.1016\/j.ebiom.2023.104551_bib29","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1001\/jamaophthalmol.2015.0471","article-title":"Prediction of juvenile-onset myopia","volume":"133","author":"Zadnik","year":"2015","journal-title":"JAMA Ophthalmol"},{"issue":"5","key":"10.1016\/j.ebiom.2023.104551_bib30","doi-asserted-by":"crossref","first-page":"921","DOI":"10.1038\/s41433-021-01805-6","article-title":"Myopia prediction: a systematic review","volume":"36","author":"Han","year":"2022","journal-title":"Eye"},{"key":"10.1016\/j.ebiom.2023.104551_bib31","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1111\/opo.12579","article-title":"A\u00a0genetic risk score and number of myopic parents independently predict myopia","volume":"38","author":"Ghorbani Mojarrad","year":"2018","journal-title":"Ophthalmic Physiol Opt"},{"issue":"12","key":"10.1016\/j.ebiom.2023.104551_bib32","doi-asserted-by":"crossref","first-page":"1607","DOI":"10.1016\/j.ophtha.2019.06.026","article-title":"Contribution of genome-wide significant single nucleotide polymorphisms in myopia prediction: findings from a 10-year cohort of Chinese twin children","volume":"126","author":"Chen","year":"2019","journal-title":"Ophthalmology"},{"key":"10.1016\/j.ebiom.2023.104551_bib33","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1001\/jamaophthalmol.2019.4421","article-title":"Association between polygenic risk score and risk of myopia","volume":"138","author":"Ghorbani Mojarrad","year":"2020","journal-title":"JAMA Ophthalmol"},{"issue":"8","key":"10.1016\/j.ebiom.2023.104551_bib34","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1167\/tvst.10.8.26","article-title":"New polygenic risk score to predict high myopia in Singapore Chinese children","volume":"10","author":"Lanca","year":"2021","journal-title":"Transl Vis Sci Technol"},{"issue":"8","key":"10.1016\/j.ebiom.2023.104551_bib35","doi-asserted-by":"crossref","first-page":"890","DOI":"10.1016\/j.ophtha.2022.03.022","article-title":"The potential of current polygenic risk scores to predict high myopia and myopic macular degeneration in multi-ethnic Singapore adults","volume":"129","author":"Kassam","year":"2022","journal-title":"Ophthalmology"},{"issue":"5","key":"10.1016\/j.ebiom.2023.104551_bib36","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1111\/opo.12403","article-title":"Genetic prediction of myopia: prospects and challenges","volume":"37","author":"Guggenheim","year":"2017","journal-title":"Ophthalmic Physiol Opt"},{"key":"10.1016\/j.ebiom.2023.104551_bib37","first-page":"621","article-title":"Assumption-free estimation of the genetic contribution to refractive error across childhood","volume":"21","author":"Guggenheim","year":"2015","journal-title":"Mol Vis"},{"issue":"11","key":"10.1016\/j.ebiom.2023.104551_bib38","doi-asserted-by":"crossref","first-page":"881","DOI":"10.1007\/s00439-018-1942-8","article-title":"Genome-wide association studies for corneal and refractive astigmatism in UK Biobank demonstrate a shared role for myopia susceptibility loci","volume":"137","author":"Shah","year":"2018","journal-title":"Hum Genet"},{"key":"10.1016\/j.ebiom.2023.104551_bib39","article-title":"Genetic prediction of myopia in different ethnic ancestries","author":"Ghorbani Mojarrad","year":"2022","journal-title":"Optom Cont Lens"},{"issue":"3","key":"10.1016\/j.ebiom.2023.104551_bib40","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pmed.1001779","article-title":"UK Biobank: an open access resource for identifying the causes of a wide range of complex diseases of middle and old age","volume":"12","author":"Sudlow","year":"2015","journal-title":"PLoS Med"},{"issue":"4","key":"10.1016\/j.ebiom.2023.104551_bib41","doi-asserted-by":"crossref","first-page":"1051","DOI":"10.1534\/genetics.115.178905","article-title":"Genotyping informatics and quality control for 100,000 subjects in the genetic epidemiology research on adult health and aging (GERA) cohort","volume":"200","author":"Kvale","year":"2015","journal-title":"Genetics"},{"issue":"4","key":"10.1016\/j.ebiom.2023.104551_bib42","doi-asserted-by":"crossref","first-page":"1285","DOI":"10.1534\/genetics.115.178616","article-title":"Characterizing race\/ethnicity and genetic ancestry for 100,000 subjects in the genetic epidemiology research on adult health and aging (GERA) cohort","volume":"200","author":"Banda","year":"2015","journal-title":"Genetics"},{"issue":"1","key":"10.1016\/j.ebiom.2023.104551_bib43","doi-asserted-by":"crossref","first-page":"936","DOI":"10.1186\/1471-2458-13-936","article-title":"Rationale, design and methods for a community-based study of clustering and cumulative effects of chronic disease processes and their effects on ageing: the Busselton healthy ageing study","volume":"13","author":"James","year":"2013","journal-title":"BMC Public Health"},{"issue":"1","key":"10.1016\/j.ebiom.2023.104551_bib44","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1093\/ije\/dys064","article-title":"Cohort profile: the 'children of the 90s'--the index offspring of the Avon longitudinal study of parents and children","volume":"42","author":"Boyd","year":"2013","journal-title":"Int J Epidemiol"},{"issue":"1","key":"10.1016\/j.ebiom.2023.104551_bib45","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1093\/ije\/dys066","article-title":"Cohort profile: the Avon longitudinal study of parents and children: ALSPAC mothers cohort","volume":"42","author":"Fraser","year":"2013","journal-title":"Int J Epidemiol"},{"issue":"6","key":"10.1016\/j.ebiom.2023.104551_bib46","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1007\/s10654-006-9022-0","article-title":"The Generation R Study: design and cohort profile","volume":"21","author":"Jaddoe","year":"2006","journal-title":"Eur J Epidemiol"},{"issue":"12","key":"10.1016\/j.ebiom.2023.104551_bib47","doi-asserted-by":"crossref","first-page":"1243","DOI":"10.1007\/s10654-016-0224-9","article-title":"The Generation R Study: design and cohort update 2017","volume":"31","author":"Kooijman","year":"2016","journal-title":"Eur J Epidemiol"},{"key":"10.1016\/j.ebiom.2023.104551_bib48","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1038\/s41588-017-0009-4","article-title":"Multi-trait analysis of genome-wide association summary statistics using MTAG","volume":"50","author":"Turley","year":"2018","journal-title":"Nat Genet"},{"issue":"22-23","key":"10.1016\/j.ebiom.2023.104551_bib49","doi-asserted-by":"crossref","first-page":"5424","DOI":"10.1093\/bioinformatics\/btaa1029","article-title":"LDpred2: better, faster, stronger","volume":"36","author":"Priv\u00e9","year":"2020","journal-title":"Bioinformatics"},{"issue":"7726","key":"10.1016\/j.ebiom.2023.104551_bib50","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1038\/s41586-018-0579-z","article-title":"The UK Biobank resource with deep phenotyping and genomic data","volume":"562","author":"Bycroft","year":"2018","journal-title":"Nature"},{"issue":"3","key":"10.1016\/j.ebiom.2023.104551_bib51","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1038\/ng.3190","article-title":"Efficient Bayesian mixed-model analysis increases association power in large cohorts","volume":"47","author":"Loh","year":"2015","journal-title":"Nat Genet"},{"issue":"1","key":"10.1016\/j.ebiom.2023.104551_bib52","doi-asserted-by":"crossref","first-page":"1776","DOI":"10.1038\/s41467-019-09718-5","article-title":"Polygenic prediction via Bayesian regression and continuous shrinkage priors","volume":"10","author":"Ge","year":"2019","journal-title":"Nat Commun"},{"issue":"1","key":"10.1016\/j.ebiom.2023.104551_bib53","doi-asserted-by":"crossref","first-page":"4192","DOI":"10.1038\/s41467-021-24485-y","article-title":"Improved genetic prediction of complex traits from individual-level data or summary statistics","volume":"12","author":"Zhang","year":"2021","journal-title":"Nat Commun"},{"issue":"6","key":"10.1016\/j.ebiom.2023.104551_bib54","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1002\/gepi.22050","article-title":"Polygenic scores via penalized regression on summary statistics","volume":"41","author":"Mak","year":"2017","journal-title":"Genet Epidemiol"},{"issue":"1","key":"10.1016\/j.ebiom.2023.104551_bib55","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/j.ophtha.2018.06.029","article-title":"Environmental risk factors can reduce axial length elongation and myopia incidence\u00a0in 6- to 9-year-old children","volume":"126","author":"Tideman","year":"2019","journal-title":"Ophthalmology"},{"key":"10.1016\/j.ebiom.2023.104551_bib56","article-title":"UK Biobank release and systematic evaluation of optimised polygenic risk scores for 53 diseases and quantitative traits","author":"Thompson","year":"2022","journal-title":"medRxiv"},{"issue":"8","key":"10.1016\/j.ebiom.2023.104551_bib57","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pgen.1005432","article-title":"APLP2 regulates refractive error and myopia development in mice and humans","volume":"11","author":"Tkatchenko","year":"2015","journal-title":"PLoS Genet"},{"key":"10.1016\/j.ebiom.2023.104551_bib58","article-title":"LightGBM: a highly efficient gradient boosting decision tree","volume":"30","author":"Ke","year":"2017","journal-title":"Adv Neural Inf Process Syst"},{"issue":"12","key":"10.1016\/j.ebiom.2023.104551_bib59","doi-asserted-by":"crossref","first-page":"1235","DOI":"10.1016\/j.oret.2021.02.006","article-title":"Deep learning approach for automated detection of myopic maculopathy and pathologic myopia in fundus images","volume":"5","author":"Du","year":"2021","journal-title":"Ophthalmol Retina"},{"issue":"4","key":"10.1016\/j.ebiom.2023.104551_bib60","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1093\/jamia\/ocz228","article-title":"A\u00a0tutorial on calibration measurements and calibration models for clinical prediction models","volume":"27","author":"Huang","year":"2020","journal-title":"J\u00a0Am Med Inform Assoc"},{"issue":"4","key":"10.1016\/j.ebiom.2023.104551_bib61","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1007\/s40471-015-0055-3","article-title":"Polygenic scores in epidemiology: risk prediction, etiology, and clinical utility","volume":"2","author":"Maher","year":"2015","journal-title":"Curr Epidemiol Rep"},{"issue":"1","key":"10.1016\/j.ebiom.2023.104551_bib62","doi-asserted-by":"crossref","DOI":"10.1016\/j.xops.2022.100113","article-title":"Genome-wide association study of axial length in population-based cohorts in Japan: the tohoku medical megabank organization eye study","volume":"2","author":"Fuse","year":"2022","journal-title":"Ophthalmol Sci"},{"issue":"4","key":"10.1016\/j.ebiom.2023.104551_bib63","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1111\/opo.12305","article-title":"Age of onset of myopia predicts risk of high myopia in later childhood in myopic Singapore children","volume":"36","author":"Chua","year":"2016","journal-title":"Ophthalmic Physiol Opt"},{"issue":"12","key":"10.1016\/j.ebiom.2023.104551_bib64","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0167642","article-title":"Identifying children at risk of high myopia using population centile curves of refraction","volume":"11","author":"Chen","year":"2016","journal-title":"PLoS One"},{"issue":"11","key":"10.1016\/j.ebiom.2023.104551_bib65","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pmed.1002674","article-title":"Prediction of myopia development among Chinese school-aged children using refraction data from electronic medical records: a retrospective, multicentre machine learning study","volume":"15","author":"Lin","year":"2018","journal-title":"PLoS Med"},{"issue":"1","key":"10.1016\/j.ebiom.2023.104551_bib66","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1111\/opo.13058","article-title":"Myopia: an ounce of prevention is worth a pound of cure","volume":"43","author":"Bullimore","year":"2023","journal-title":"Ophthalmic Physiol Opt"},{"issue":"7933","key":"10.1016\/j.ebiom.2023.104551_bib67","doi-asserted-by":"crossref","first-page":"704","DOI":"10.1038\/s41586-022-05275-y","article-title":"A\u00a0saturated map of common genetic variants associated with human height","volume":"610","author":"Yengo","year":"2022","journal-title":"Nature"},{"issue":"1","key":"10.1016\/j.ebiom.2023.104551_bib68","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/j.ajhg.2018.11.008","article-title":"Leveraging polygenic functional enrichment to improve GWAS power","volume":"104","author":"Kichaev","year":"2019","journal-title":"Am J Hum Genet"},{"issue":"12","key":"10.1016\/j.ebiom.2023.104551_bib69","doi-asserted-by":"crossref","first-page":"1355","DOI":"10.1038\/s41588-020-00735-5","article-title":"Functionally informed fine-mapping and polygenic localization of complex trait heritability","volume":"52","author":"Weissbrod","year":"2020","journal-title":"Nat Genet"},{"issue":"8","key":"10.1016\/j.ebiom.2023.104551_bib70","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1093\/hmg\/ddab053","article-title":"Imputed gene expression risk scores: a functionally informed component of polygenic risk","volume":"30","author":"Pain","year":"2021","journal-title":"Hum Mol Genet"},{"issue":"1","key":"10.1016\/j.ebiom.2023.104551_bib71","doi-asserted-by":"crossref","first-page":"6052","DOI":"10.1038\/s41467-021-25171-9","article-title":"Incorporating functional priors improves polygenic prediction accuracy in UK Biobank and 23andMe data sets","volume":"12","author":"M\u00e1rquez-Luna","year":"2021","journal-title":"Nat Commun"},{"issue":"4","key":"10.1016\/j.ebiom.2023.104551_bib72","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1038\/s41588-022-01036-9","article-title":"Leveraging fine-mapping and multipopulation training data to improve cross-population polygenic risk scores","volume":"54","author":"Weissbrod","year":"2022","journal-title":"Nat Genet"},{"issue":"6374","key":"10.1016\/j.ebiom.2023.104551_bib73","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1126\/science.aan6877","article-title":"The nature of nurture: effects of parental genotypes","volume":"359","author":"Kong","year":"2018","journal-title":"Science"},{"issue":"11","key":"10.1016\/j.ebiom.2023.104551_bib74","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pgen.1010478","article-title":"Education interacts with genetic variants near GJD2, RBFOX1, LAMA2, KCNQ5 and LRRC4C to confer susceptibility to myopia","volume":"18","author":"Clark","year":"2022","journal-title":"PLoS Genet"},{"issue":"9","key":"10.1016\/j.ebiom.2023.104551_bib75","doi-asserted-by":"crossref","first-page":"1345","DOI":"10.1038\/s41588-022-01158-0","article-title":"Gene\u2013environment correlations across geographic regions affect genome-wide association studies","volume":"54","author":"Abdellaoui","year":"2022","journal-title":"Nat Genet"},{"issue":"11","key":"10.1016\/j.ebiom.2023.104551_bib76","doi-asserted-by":"crossref","first-page":"1226","DOI":"10.1038\/s41431-022-01126-6","article-title":"Assessing the contribution of genetic nurture to refractive error","volume":"30","author":"Guggenheim","year":"2022","journal-title":"Eur J Hum Genet"},{"issue":"2","key":"10.1016\/j.ebiom.2023.104551_bib77","doi-asserted-by":"crossref","first-page":"1158","DOI":"10.1167\/iovs.16-20894","article-title":"Time outdoors at specific ages during early childhood and the risk of incident myopia","volume":"58","author":"Shah","year":"2017","journal-title":"Invest Ophthalmol Vis Sci"}],"container-title":["eBioMedicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2352396423001160?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2352396423001160?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,6]],"date-time":"2025-11-06T19:25:15Z","timestamp":1762457115000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2352396423001160"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,5]]},"references-count":77,"alternative-id":["S2352396423001160"],"URL":"https:\/\/doi.org\/10.1016\/j.ebiom.2023.104551","relation":{},"ISSN":["2352-3964"],"issn-type":[{"value":"2352-3964","type":"print"}],"subject":[],"published":{"date-parts":[[2023,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A new polygenic score for refractive error improves detection of children at risk of high myopia but not the prediction of those at risk of myopic macular degeneration","name":"articletitle","label":"Article Title"},{"value":"eBioMedicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ebiom.2023.104551","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 The Author(s). Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"104551"}}