{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T20:57:15Z","timestamp":1793393835011,"version":"4.5.0"},"reference-count":59,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,7,24]],"date-time":"2023-07-24T00:00:00Z","timestamp":1690156800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81670352"],"award-info":[{"award-number":["81670352"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81970327"],"award-info":[{"award-number":["81970327"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82000368"],"award-info":[{"award-number":["82000368"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["thelancet.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["eBioMedicine"],"published-print":{"date-parts":[[2023,9]]},"DOI":"10.1016\/j.ebiom.2023.104744","type":"journal-article","created":{"date-parts":[[2023,8,7]],"date-time":"2023-08-07T23:07:19Z","timestamp":1691449639000},"page":"104744","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":114,"special_numbering":"C","title":["Interleukin-34-NF-\u03baB signaling aggravates myocardial ischemic\/reperfusion injury by facilitating macrophage recruitment and polarization"],"prefix":"10.1016","volume":"95","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2723-3202","authenticated-orcid":false,"given":"Lingfang","family":"Zhuang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiao","family":"Zong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qian","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qin","family":"Fan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rong","family":"Tao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"6","key":"10.1016\/j.ebiom.2023.104744_bib1","doi-asserted-by":"crossref","first-page":"1105","DOI":"10.1002\/ehf2.12555","article-title":"Highlights in heart failure","volume":"6","author":"Tomasoni","year":"2019","journal-title":"ESC Heart Fail"},{"issue":"6","key":"10.1016\/j.ebiom.2023.104744_bib2","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCHEARTFAILURE.120.007132","article-title":"Risk profiles in heart failure: baseline, residual, worsening, and advanced heart failure risk","volume":"13","author":"Greene","year":"2020","journal-title":"Circ Heart Fail"},{"issue":"5","key":"10.1016\/j.ebiom.2023.104744_bib3","doi-asserted-by":"crossref","first-page":"844","DOI":"10.1093\/cvr\/cvz035","article-title":"Common risk factors for heart failure and cancer","volume":"115","author":"Meijers","year":"2019","journal-title":"Cardiovasc Res"},{"issue":"6","key":"10.1016\/j.ebiom.2023.104744_bib4","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1038\/nrcardio.2016.25","article-title":"Epidemiology and aetiology of heart failure","volume":"13","author":"Ziaeian","year":"2016","journal-title":"Nat Rev Cardiol"},{"issue":"11","key":"10.1016\/j.ebiom.2023.104744_bib5","doi-asserted-by":"crossref","first-page":"1121","DOI":"10.1056\/NEJMra071667","article-title":"Myocardial reperfusion injury","volume":"357","author":"Yellon","year":"2007","journal-title":"N\u00a0Engl J Med"},{"issue":"11","key":"10.1016\/j.ebiom.2023.104744_bib6","doi-asserted-by":"crossref","first-page":"1391","DOI":"10.1038\/nm.2507","article-title":"Ischemia and reperfusion--from mechanism to translation","volume":"17","author":"Eltzschig","year":"2011","journal-title":"Nat Med"},{"issue":"1","key":"10.1016\/j.ebiom.2023.104744_bib7","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1161\/CIRCRESAHA.116.303577","article-title":"The biological basis for cardiac repair after myocardial infarction: from inflammation to fibrosis","volume":"119","author":"Prabhu","year":"2016","journal-title":"Circ Res"},{"issue":"15","key":"10.1016\/j.ebiom.2023.104744_bib8","doi-asserted-by":"crossref","first-page":"1629","DOI":"10.1016\/j.jacc.2009.08.089","article-title":"Impaired infarct healing in atherosclerotic mice with Ly-6C(hi) monocytosis","volume":"55","author":"Panizzi","year":"2010","journal-title":"J\u00a0Am Coll Cardiol"},{"issue":"3","key":"10.1016\/j.ebiom.2023.104744_bib9","doi-asserted-by":"crossref","first-page":"818","DOI":"10.2353\/ajpath.2007.060547","article-title":"Macrophage depletion impairs wound healing and increases left ventricular remodeling after myocardial injury in mice","volume":"170","author":"van Amerongen","year":"2007","journal-title":"Am J Pathol"},{"issue":"12","key":"10.1016\/j.ebiom.2023.104744_bib10","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1038\/s41577-018-0065-8","article-title":"Cardioimmunology: the immune system in cardiac homeostasis and disease","volume":"18","author":"Swirski","year":"2018","journal-title":"Nat Rev Immunol"},{"key":"10.1016\/j.ebiom.2023.104744_bib11","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.43882","article-title":"Single-cell expression profiling reveals dynamic flux of cardiac stromal, vascular and immune cells in health and injury","volume":"8","author":"Farbehi","year":"2019","journal-title":"Elife"},{"issue":"1","key":"10.1016\/j.ebiom.2023.104744_bib12","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.immuni.2013.11.019","article-title":"Embryonic and adult-derived resident cardiac macrophages are maintained through distinct mechanisms at steady state and during inflammation","volume":"40","author":"Epelman","year":"2014","journal-title":"Immunity"},{"issue":"6","key":"10.1016\/j.ebiom.2023.104744_bib13","doi-asserted-by":"crossref","first-page":"651","DOI":"10.2174\/1389450118666171031115025","article-title":"Macrophage polarization as a therapeutic target in myocardial infarction","volume":"19","author":"Cheng","year":"2018","journal-title":"Curr Drug Targets"},{"key":"10.1016\/j.ebiom.2023.104744_bib14","doi-asserted-by":"crossref","DOI":"10.1155\/2015\/816460","article-title":"Understanding the mysterious M2 macrophage through activation markers and effector mechanisms","volume":"2015","author":"Roszer","year":"2015","journal-title":"Mediators Inflamm"},{"issue":"5","key":"10.1016\/j.ebiom.2023.104744_bib15","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1161\/CIRCULATIONAHA.118.036044","article-title":"Dectin-1 contributes to myocardial ischemia\/reperfusion injury by regulating macrophage polarization and neutrophil infiltration","volume":"139","author":"Fan","year":"2019","journal-title":"Circulation"},{"issue":"7","key":"10.1016\/j.ebiom.2023.104744_bib16","doi-asserted-by":"crossref","first-page":"1116","DOI":"10.1161\/CIRCRESAHA.116.310260","article-title":"Dectin-2 deficiency modulates Th1 differentiation and improves wound healing after myocardial infarction","volume":"120","author":"Yan","year":"2017","journal-title":"Circ Res"},{"issue":"8","key":"10.1016\/j.ebiom.2023.104744_bib17","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1161\/CIRCRESAHA.119.315807","article-title":"Lgr4 governs a pro-inflammatory program in macrophages to antagonize post-infarction cardiac repair","volume":"127","author":"Huang","year":"2020","journal-title":"Circ Res"},{"issue":"3","key":"10.1016\/j.ebiom.2023.104744_bib18","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1189\/jlb.1209822","article-title":"Functional overlap but differential expression of CSF-1 and IL-34 in their CSF-1 receptor-mediated regulation of myeloid cells","volume":"88","author":"Wei","year":"2010","journal-title":"J\u00a0Leukoc Biol"},{"issue":"5877","key":"10.1016\/j.ebiom.2023.104744_bib19","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1126\/science.1154370","article-title":"Discovery of a cytokine and its receptor by functional screening of the extracellular proteome","volume":"320","author":"Lin","year":"2008","journal-title":"Science"},{"issue":"14","key":"10.1016\/j.ebiom.2023.104744_bib20","doi-asserted-by":"crossref","first-page":"2569","DOI":"10.1007\/s00018-017-2482-4","article-title":"Immunoregulatory properties of the cytokine IL-34","volume":"74","author":"Guillonneau","year":"2017","journal-title":"Cell Mol Life Sci"},{"issue":"1","key":"10.1016\/j.ebiom.2023.104744_bib21","doi-asserted-by":"crossref","first-page":"3462","DOI":"10.1038\/s41598-018-21859-z","article-title":"Elevated serum interleukin-34 level in patients with systemic lupus erythematosus is associated with disease activity","volume":"8","author":"Xie","year":"2018","journal-title":"Sci Rep"},{"issue":"1","key":"10.1016\/j.ebiom.2023.104744_bib22","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1007\/s10067-017-3746-y","article-title":"Increased IL-6 expression on THP-1 by IL-34 stimulation up-regulated rheumatoid arthritis Th17 cells","volume":"37","author":"Wang","year":"2018","journal-title":"Clin Rheumatol"},{"issue":"10","key":"10.1016\/j.ebiom.2023.104744_bib23","doi-asserted-by":"crossref","first-page":"1216","DOI":"10.1111\/1346-8138.14538","article-title":"Serum interleukin-34 levels in patients with systemic sclerosis: clinical association with interstitial lung disease","volume":"45","author":"Kuzumi","year":"2018","journal-title":"J\u00a0Dermatol"},{"issue":"5","key":"10.1016\/j.ebiom.2023.104744_bib24","first-page":"1866","article-title":"Increased serum interleukin-34 in patients\u00a0with coronary artery disease","volume":"40","author":"Li","year":"2012","journal-title":"J\u00a0Int Med Res"},{"key":"10.1016\/j.ebiom.2023.104744_bib25","doi-asserted-by":"crossref","first-page":"904","DOI":"10.3389\/fphys.2018.00904","article-title":"Increased serum interleukin-34 levels are related to the presence and severity of cardiac dysfunction in patients with ischemic cardiomyopathy","volume":"9","author":"Xi","year":"2018","journal-title":"Front Physiol"},{"issue":"4","key":"10.1016\/j.ebiom.2023.104744_bib26","article-title":"Prognostic significance of interleukin-34 (IL-34) in patients with chronic heart failure with or without renal insufficiency","volume":"6","author":"Tao","year":"2017","journal-title":"J\u00a0Am Heart Assoc"},{"issue":"8","key":"10.1016\/j.ebiom.2023.104744_bib27","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1038\/ni.2360","article-title":"IL-34 is a tissue-restricted ligand of CSF1R required for the development of Langerhans cells and microglia","volume":"13","author":"Wang","year":"2012","journal-title":"Nat Immunol"},{"issue":"8","key":"10.1016\/j.ebiom.2023.104744_bib28","doi-asserted-by":"crossref","first-page":"3198","DOI":"10.1172\/JCI81166","article-title":"IL-34 mediates acute kidney injury and worsens subsequent chronic kidney disease","volume":"125","author":"Baek","year":"2015","journal-title":"J\u00a0Clin Invest"},{"key":"10.1016\/j.ebiom.2023.104744_bib29","doi-asserted-by":"crossref","DOI":"10.3389\/fcvm.2020.615161","article-title":"Comprehensive integration of single-cell transcriptional profiling reveals the heterogeneities of non-cardiomyocytes in healthy and ischemic hearts","volume":"7","author":"Zhuang","year":"2020","journal-title":"Front Cardiovasc Med"},{"issue":"7924","key":"10.1016\/j.ebiom.2023.104744_bib30","doi-asserted-by":"crossref","first-page":"766","DOI":"10.1038\/s41586-022-05060-x","article-title":"Spatial multi-omic map of human myocardial infarction","volume":"608","author":"Kuppe","year":"2022","journal-title":"Nature"},{"issue":"2","key":"10.1016\/j.ebiom.2023.104744_bib31","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1002\/(SICI)1097-0177(199702)208:2<211::AID-AJA8>3.0.CO;2-L","article-title":"Isolation and characterization of the platelet-derived growth factor beta receptor promoter","volume":"208","author":"Shinbrot","year":"1997","journal-title":"Dev Dyn"},{"issue":"6","key":"10.1016\/j.ebiom.2023.104744_bib32","doi-asserted-by":"crossref","first-page":"H1056","DOI":"10.1152\/ajpheart.00459.2021","article-title":"Guidelines for in\u00a0vivo mouse models of myocardial infarction","volume":"321","author":"Lindsey","year":"2021","journal-title":"Am J Physiol Heart Circ Physiol"},{"issue":"1","key":"10.1016\/j.ebiom.2023.104744_bib33","doi-asserted-by":"crossref","first-page":"H208","DOI":"10.1152\/ajpheart.00234.2021","article-title":"Reperfused vs. nonreperfused myocardial infarction: when to use which model","volume":"321","author":"Lindsey","year":"2021","journal-title":"Am J Physiol Heart Circ Physiol"},{"issue":"4","key":"10.1016\/j.ebiom.2023.104744_bib34","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1007\/s00395-018-0686-x","article-title":"Mapping macrophage polarization over the myocardial infarction time continuum","volume":"113","author":"Mouton","year":"2018","journal-title":"Basic Res Cardiol"},{"issue":"6","key":"10.1016\/j.ebiom.2023.104744_bib35","doi-asserted-by":"crossref","first-page":"887","DOI":"10.1161\/CIRCRESAHA.121.319478","article-title":"Targeting CaMKII-delta9 ameliorates cardiac ischemia\/reperfusion injury by inhibiting myocardial inflammation","volume":"130","author":"Yao","year":"2022","journal-title":"Circ Res"},{"issue":"2","key":"10.1016\/j.ebiom.2023.104744_bib36","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1016\/S0735-1097(01)01377-8","article-title":"Nuclear factor kappa-B and the heart","volume":"38","author":"Valen","year":"2001","journal-title":"J\u00a0Am Coll Cardiol"},{"issue":"4","key":"10.1016\/j.ebiom.2023.104744_bib37","doi-asserted-by":"crossref","DOI":"10.1101\/cshperspect.a000034","article-title":"The NF-kappaB family of transcription factors and its regulation","volume":"1","author":"Oeckinghaus","year":"2009","journal-title":"Cold Spring Harb Perspect Biol"},{"issue":"1","key":"10.1016\/j.ebiom.2023.104744_bib38","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1186\/s12931-023-02428-z","article-title":"Submersion and hypoxia inhibit alveolar epithelial Na(+) transport through ERK\/NF-kappaB signaling pathway","volume":"24","author":"Zhou","year":"2023","journal-title":"Respir Res"},{"issue":"Pt 1","key":"10.1016\/j.ebiom.2023.104744_bib39","article-title":"Polystyrene nanoplastics deteriorate LPS-modulated duodenal permeability and inflammation in mice via ROS drived-NF-kappaB\/NLRP3 pathway","volume":"307","author":"He","year":"2022","journal-title":"Chemosphere"},{"issue":"20","key":"10.1016\/j.ebiom.2023.104744_bib40","doi-asserted-by":"crossref","first-page":"6030","DOI":"10.1158\/0008-5472.CAN-16-1170","article-title":"Chemotherapy-induced IL34 enhances immunosuppression by tumor-associated macrophages and mediates survival of chemoresistant lung cancer cells","volume":"76","author":"Baghdadi","year":"2016","journal-title":"Cancer Res"},{"issue":"3","key":"10.1016\/j.ebiom.2023.104744_bib41","first-page":"2279","article-title":"Analysis of expression levels of IL-17 and IL-34 and influencing factors for prognosis in patients with lupus nephritis","volume":"17","author":"Cheng","year":"2019","journal-title":"Exp Ther Med"},{"issue":"3","key":"10.1016\/j.ebiom.2023.104744_bib42","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1042\/CS20150176","article-title":"Interleukin 34: a new modulator of human and experimental inflammatory bowel disease","volume":"129","author":"Zwicker","year":"2015","journal-title":"Clin Sci (Lond)"},{"issue":"1","key":"10.1016\/j.ebiom.2023.104744_bib43","doi-asserted-by":"crossref","first-page":"7987","DOI":"10.1038\/s41598-020-64932-2","article-title":"Interleukin-34 overexpression mediated through tumor necrosis factor-alpha reflects severity of synovitis in knee osteoarthritis","volume":"10","author":"Udomsinprasert","year":"2020","journal-title":"Sci Rep"},{"issue":"12","key":"10.1016\/j.ebiom.2023.104744_bib44","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0081665","article-title":"The newly discovered cytokine IL-34 is expressed in gingival fibroblasts, shows enhanced expression by pro-inflammatory cytokines, and stimulates osteoclast differentiation","volume":"8","author":"Bostrom","year":"2013","journal-title":"PLoS One"},{"issue":"3","key":"10.1016\/j.ebiom.2023.104744_bib45","doi-asserted-by":"crossref","first-page":"949","DOI":"10.1038\/s41418-019-0390-x","article-title":"Fate decision of satellite cell differentiation and self-renewal by miR-31-IL34 axis","volume":"27","author":"Su","year":"2020","journal-title":"Cell Death Differ"},{"issue":"5","key":"10.1016\/j.ebiom.2023.104744_bib46","doi-asserted-by":"crossref","first-page":"1560","DOI":"10.1002\/hep.28445","article-title":"miR-28-5p-IL-34-macrophage feedback loop modulates hepatocellular carcinoma metastasis","volume":"63","author":"Zhou","year":"2016","journal-title":"Hepatology"},{"issue":"6","key":"10.1016\/j.ebiom.2023.104744_bib47","doi-asserted-by":"crossref","first-page":"2131","DOI":"10.4049\/jimmunol.1600446","article-title":"IL-35 decelerates the inflammatory process by regulating inflammatory cytokine secretion and M1\/M2 macrophage ratio in psoriasis","volume":"197","author":"Zhang","year":"2016","journal-title":"J\u00a0Immunol"},{"issue":"1","key":"10.1016\/j.ebiom.2023.104744_bib48","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1111\/imm.12173","article-title":"A\u00a0critical role for suppressor of cytokine signalling 3 in promoting M1 macrophage activation and function in\u00a0vitro and in\u00a0vivo","volume":"141","author":"Arnold","year":"2014","journal-title":"Immunology"},{"issue":"12","key":"10.1016\/j.ebiom.2023.104744_bib49","doi-asserted-by":"crossref","first-page":"2398","DOI":"10.1016\/j.cmet.2021.10.004","article-title":"Mitochondrial metabolism coordinates stage-specific repair processes in macrophages during wound healing","volume":"33","author":"Willenborg","year":"2021","journal-title":"Cell Metab"},{"issue":"6","key":"10.1016\/j.ebiom.2023.104744_bib50","doi-asserted-by":"crossref","first-page":"1050","DOI":"10.1016\/j.immuni.2012.11.001","article-title":"Stroma-derived interleukin-34 controls the development and maintenance of langerhans cells and the maintenance of microglia","volume":"37","author":"Greter","year":"2012","journal-title":"Immunity"},{"issue":"9","key":"10.1016\/j.ebiom.2023.104744_bib51","doi-asserted-by":"crossref","first-page":"1409","DOI":"10.1093\/ndt\/gfw026","article-title":"Chronicity following ischaemia-reperfusion injury depends on tubular-macrophage crosstalk involving two tubular cell-derived CSF-1R activators: CSF-1 and IL-34","volume":"31","author":"Sanchez-Nino","year":"2016","journal-title":"Nephrol Dial Transplant"},{"key":"10.1016\/j.ebiom.2023.104744_bib52","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1016\/j.fsi.2020.05.073","article-title":"IL-34 regulates the inflammatory response and anti-bacterial immune defense of Japanese flounder Paralichthys olivaceus","volume":"104","author":"Yu","year":"2020","journal-title":"Fish Shellfish Immunol"},{"issue":"2","key":"10.1016\/j.ebiom.2023.104744_bib53","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0056045","article-title":"IL-34 induces the differentiation of human monocytes into immunosuppressive macrophages. antagonistic effects of GM-CSF and IFNgamma","volume":"8","author":"Foucher","year":"2013","journal-title":"PLoS One"},{"issue":"4","key":"10.1016\/j.ebiom.2023.104744_bib54","doi-asserted-by":"crossref","first-page":"1093","DOI":"10.2353\/ajpath.2007.061191","article-title":"Macrophage colony-stimulating factor improves cardiac function after ischemic injury by inducing vascular endothelial growth factor production and survival of cardiomyocytes","volume":"171","author":"Okazaki","year":"2007","journal-title":"Am J Pathol"},{"issue":"3","key":"10.1016\/j.ebiom.2023.104744_bib55","doi-asserted-by":"crossref","first-page":"626","DOI":"10.1016\/j.jacc.2005.09.037","article-title":"Macrophage colony-stimulating factor treatment after myocardial infarction attenuates left ventricular dysfunction by accelerating infarct repair","volume":"47","author":"Yano","year":"2006","journal-title":"J\u00a0Am Coll Cardiol"},{"issue":"3","key":"10.1016\/j.ebiom.2023.104744_bib56","doi-asserted-by":"crossref","first-page":"1114","DOI":"10.1182\/blood-2003-08-2739","article-title":"Incomplete restoration of colony-stimulating factor 1 (CSF-1) function in CSF-1-deficient Csf1op\/Csf1op mice by transgenic expression of cell surface CSF-1","volume":"103","author":"Dai","year":"2004","journal-title":"Blood"},{"issue":"5","key":"10.1016\/j.ebiom.2023.104744_bib57","doi-asserted-by":"crossref","first-page":"1010","DOI":"10.1016\/j.bbamcr.2015.01.023","article-title":"Syndecan-1 regulates the biological activities of interleukin-34","volume":"1853","author":"Segaliny","year":"2015","journal-title":"Biochim Biophys Acta"},{"issue":"26","key":"10.1016\/j.ebiom.2023.104744_bib58","first-page":"3184","article-title":"TREM2 acts as a receptor for IL-34 to suppress acute myeloid leukemia in mice","volume":"141","author":"Xie","year":"2023","journal-title":"Blood"},{"key":"10.1016\/j.ebiom.2023.104744_bib59","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/j.intimp.2018.05.023","article-title":"IL-34 regulates IL-6 and IL-8 production in human lung fibroblasts via MAPK, PI3K-Akt, JAK and NF-kappaB signaling pathways","volume":"61","author":"Zhou","year":"2018","journal-title":"Int Immunopharmacol"}],"container-title":["eBioMedicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2352396423003092?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2352396423003092?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,6]],"date-time":"2025-11-06T19:28:18Z","timestamp":1762457298000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2352396423003092"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,9]]},"references-count":59,"alternative-id":["S2352396423003092"],"URL":"https:\/\/doi.org\/10.1016\/j.ebiom.2023.104744","relation":{},"ISSN":["2352-3964"],"issn-type":[{"value":"2352-3964","type":"print"}],"subject":[],"published":{"date-parts":[[2023,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Interleukin-34-NF-\u03baB signaling aggravates myocardial ischemic\/reperfusion injury by facilitating macrophage recruitment and polarization","name":"articletitle","label":"Article Title"},{"value":"eBioMedicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ebiom.2023.104744","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 The Author(s). Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"104744"}}