{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T16:59:48Z","timestamp":1783011588421,"version":"3.54.6"},"reference-count":10,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,12,1]],"date-time":"2023-12-01T00:00:00Z","timestamp":1701388800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,12,1]],"date-time":"2023-12-01T00:00:00Z","timestamp":1701388800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,11,6]],"date-time":"2023-11-06T00:00:00Z","timestamp":1699228800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["thelancet.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["eBioMedicine"],"published-print":{"date-parts":[[2023,12]]},"DOI":"10.1016\/j.ebiom.2023.104882","type":"journal-article","created":{"date-parts":[[2023,11,17]],"date-time":"2023-11-17T12:35:22Z","timestamp":1700224522000},"page":"104882","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"special_numbering":"C","title":["Centrally and peripherally altered glucose transporters: is it time to revisit energy deficiency as a potential treatment strategy in Huntington's disease?"],"prefix":"10.1016","volume":"98","author":[{"given":"Maria","family":"Bj\u00f6rkqvist","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"4","key":"10.1016\/j.ebiom.2023.104882_bib1","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1038\/nrneurol.2014.24","article-title":"Huntington disease: natural history, biomarkers and prospects for therapeutics","volume":"10","author":"Ross","year":"2014","journal-title":"Nat Rev Neurol"},{"issue":"11","key":"10.1016\/j.ebiom.2023.104882_bib2","doi-asserted-by":"crossref","first-page":"1135","DOI":"10.1016\/S1474-4422(15)00177-5","article-title":"Treating the whole body in Huntington's disease","volume":"14","author":"Carroll","year":"2015","journal-title":"Lancet Neurol"},{"issue":"1","key":"10.1016\/j.ebiom.2023.104882_bib3","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1002\/mds.28823","article-title":"Juvenile-onset Huntington disease pathophysiology and neurodevelopment: a review","volume":"37","author":"Bakels","year":"2022","journal-title":"Mov Disord"},{"issue":"Pt 3","key":"10.1016\/j.ebiom.2023.104882_bib4","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1093\/brain\/awp336","article-title":"Glucose transporter-1 deficiency syndrome: the expanding clinical and genetic spectrum of a treatable disorder","volume":"133","author":"Leen","year":"2010","journal-title":"Brain"},{"issue":"1","key":"10.1016\/j.ebiom.2023.104882_bib5","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1186\/s13059-022-02752-5","article-title":"Abnormal molecular signatures of inflammation, energy metabolism, and vesicle biology in human Huntington disease peripheral tissues","volume":"23","author":"Neueder","year":"2022","journal-title":"Genome Biol"},{"issue":"7765","key":"10.1016\/j.ebiom.2023.104882_bib6","doi-asserted-by":"crossref","first-page":"1356","DOI":"10.1016\/S0140-6736(72)91092-6","article-title":"Increased frequency of diabetes mellitus in patients with Huntington's chorea","volume":"1","author":"Podolsky","year":"1972","journal-title":"Lancet"},{"issue":"7","key":"10.1016\/j.ebiom.2023.104882_bib7","doi-asserted-by":"crossref","first-page":"1147","DOI":"10.1007\/s00726-017-2417-2","article-title":"Glucose transportation in the brain and its impairment in Huntington disease: one more shade of the energetic metabolism failure?","volume":"49","author":"Morea","year":"2017","journal-title":"Amino Acids"},{"key":"10.1016\/j.ebiom.2023.104882_bib8","doi-asserted-by":"crossref","DOI":"10.1016\/j.ebiom.2023.104849","article-title":"GLUT-1 changes in paediatric Huntington disease brain cortex and fibroblasts: an observational case-control study","volume":"97","author":"Tramutola","year":"2023","journal-title":"eBioMedicine"},{"issue":"1","key":"10.1016\/j.ebiom.2023.104882_bib9","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/S1474-4422(17)30408-8","article-title":"Mechanisms of action for the medium-chain triglyceride ketogenic diet in neurological and metabolic disorders","volume":"17","author":"Augustin","year":"2018","journal-title":"Lancet Neurol"},{"issue":"5","key":"10.1016\/j.ebiom.2023.104882_bib10","doi-asserted-by":"crossref","first-page":"490","DOI":"10.1212\/WNL.0000000000001214","article-title":"Triheptanoin improves brain energy metabolism in patients with Huntington disease","volume":"84","author":"Adanyeguh","year":"2015","journal-title":"Neurology"}],"container-title":["eBioMedicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2352396423004486?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2352396423004486?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,1,20]],"date-time":"2025-01-20T14:42:21Z","timestamp":1737384141000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2352396423004486"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,12]]},"references-count":10,"alternative-id":["S2352396423004486"],"URL":"https:\/\/doi.org\/10.1016\/j.ebiom.2023.104882","relation":{},"ISSN":["2352-3964"],"issn-type":[{"value":"2352-3964","type":"print"}],"subject":[],"published":{"date-parts":[[2023,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Centrally and peripherally altered glucose transporters: is it time to revisit energy deficiency as a potential treatment strategy in Huntington's disease?","name":"articletitle","label":"Article Title"},{"value":"eBioMedicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ebiom.2023.104882","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"https:\/\/doi.org\/10.1016\/j.ebiom.2023.104849","name":"associatedlink","label":"CrossRef DOI link to the associated document"},{"value":"simple-article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 The Author. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"104882"}}