{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,16]],"date-time":"2026-04-16T22:58:10Z","timestamp":1776380290217,"version":"3.51.2"},"reference-count":62,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,5,24]],"date-time":"2024-05-24T00:00:00Z","timestamp":1716508800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000265","name":"UKRI Medical Research Council","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000265","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010269","name":"Wellcome Trust","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100010269","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000865","name":"Bill & Melinda Gates Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000865","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010663","name":"European Research Council","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100010663","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["thelancet.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["eBioMedicine"],"published-print":{"date-parts":[[2024,7]]},"DOI":"10.1016\/j.ebiom.2024.105190","type":"journal-article","created":{"date-parts":[[2024,6,19]],"date-time":"2024-06-19T09:07:49Z","timestamp":1718788069000},"page":"105190","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"special_numbering":"C","title":["Plasmodium falciparum gametocyte production correlates with genetic markers of parasite replication but is not influenced by experimental exposure to mosquito biting"],"prefix":"10.1016","volume":"105","author":[{"given":"Sara Lynn","family":"Blanken","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aissata","family":"Barry","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kjerstin","family":"Lanke","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Moussa","family":"Guelbeogo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3520-6637","authenticated-orcid":false,"given":"Alphonse","family":"Ouedraogo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Issiaka","family":"Soulama","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sam Aboubacar","family":"Coulibaly","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karina","family":"Teelen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wouter","family":"Graumans","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elin","family":"Dumont","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Will","family":"Stone","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jordache","family":"Ramjith","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1040-9566","authenticated-orcid":false,"given":"Matthias","family":"Marti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9763-8857","authenticated-orcid":false,"given":"Carolina M.","family":"Andrade","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4863-075X","authenticated-orcid":false,"given":"Chris","family":"Drakeley","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katharine","family":"Collins","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alfred","family":"Tiono","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2666-094X","authenticated-orcid":false,"given":"Teun","family":"Bousema","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ebiom.2024.105190_bib1","series-title":"World malaria report 2022","year":"2022"},{"issue":"11","key":"10.1016\/j.ebiom.2024.105190_bib2","article-title":"malERA: an updated research agenda for characterising the reservoir and measuring transmission in malaria elimination and eradication","volume":"14","year":"2017","journal-title":"PLoS Med"},{"issue":"1","key":"10.1016\/j.ebiom.2024.105190_bib3","doi-asserted-by":"crossref","first-page":"1133","DOI":"10.1038\/s41467-017-01270-4","article-title":"Examining the human infectious reservoir for Plasmodium falciparum malaria in areas of differing transmission intensity","volume":"8","author":"Goncalves","year":"2017","journal-title":"Nat Commun"},{"issue":"2140","key":"10.1016\/j.ebiom.2024.105190_bib4","article-title":"Plasmodium falciparum sexual differentiation in malaria patients is associated with\u00a0host factors and GDV1-dependent genes","volume":"10","author":"Usui","year":"2019","journal-title":"Nat Commun"},{"issue":"244","key":"10.1016\/j.ebiom.2024.105190_bib5","doi-asserted-by":"crossref","DOI":"10.1126\/scitranslmed.3008882","article-title":"Plasmodium falciparum transmission stages accumulate in the human bone marrow","volume":"6","author":"Joice","year":"2014","journal-title":"Sci Transl Med"},{"issue":"7491","key":"10.1016\/j.ebiom.2024.105190_bib6","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1038\/nature12920","article-title":"A\u00a0transcriptional switch underlies commitment to sexual development in malaria parasites","volume":"507","author":"Kafsack","year":"2014","journal-title":"Nature"},{"issue":"2433","key":"10.1016\/j.ebiom.2024.105190_bib7","article-title":"Higher gametocyte production and mosquito infectivity in chronic compared to incident Plasmodium falciparum infections","volume":"12","author":"Barry","year":"2021","journal-title":"Nat Commun"},{"issue":"7072","key":"10.1016\/j.ebiom.2024.105190_bib8","article-title":"Plasmodium falciparum gametocyte carriage in longitudinally monitored incident infections is associated with duration of infection and human host factors","volume":"13","author":"Andolina","year":"2023","journal-title":"Sci\u00a0Rep"},{"issue":"4","key":"10.1016\/j.ebiom.2024.105190_bib9","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pcbi.1003025","article-title":"Malaria's missing number: calculating the human component of R0 by a within-host mechanistic model of Plasmodium falciparum infection and transmission","volume":"9","author":"Johnston","year":"2013","journal-title":"PLoS Comput Biol"},{"issue":"2","key":"10.1016\/j.ebiom.2024.105190_bib10","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1046\/j.1365-3156.1999.00361.x","article-title":"Host haematological factors influencing the transmission of Plasmodium falciparum gametocytes to Anopheles gambiae s.s. mosquitoes","volume":"4","author":"Drakeley","year":"1999","journal-title":"Trop Med Int Health"},{"issue":"4","key":"10.1016\/j.ebiom.2024.105190_bib11","doi-asserted-by":"crossref","first-page":"626","DOI":"10.4269\/ajtmh.2007.76.626","article-title":"Age-dependent distribution of Plasmodium falciparum gametocytes quantified by Pfs25 real-time QT-NASBA in a cross-sectional study in Burkina Faso","volume":"76","author":"Ou\u00e9draogo","year":"2007","journal-title":"Am J Trop Med Hyg"},{"issue":"3\u20134","key":"10.1016\/j.ebiom.2024.105190_bib12","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/j.ijpara.2010.09.008","article-title":"Human immune responses that reduce the transmission of Plasmodium falciparum in African populations","volume":"41","author":"Bousema","year":"2011","journal-title":"Int J Parasitol"},{"key":"10.1016\/j.ebiom.2024.105190_bib13","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.85140.sa2","article-title":"Plasmodium falciparum adapts its investment into replication versus transmission according to the host environment","author":"Abdi","year":"2023","journal-title":"Elife"},{"key":"10.1016\/j.ebiom.2024.105190_bib14","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1098\/rspb.1967.0079","article-title":"The 24-hours periodicity of microfilariae: biological mechanisms responsible for its production and control","volume":"169","author":"Hawking","year":"1967","journal-title":"Proc R Soc Lond B"},{"key":"10.1016\/j.ebiom.2024.105190_bib15","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/j.vetpar.2017.07.010","article-title":"Seasonality and circadian variation of microfilaremia in dogs experimentally infected with Dirofilaria immitis","volume":"243","author":"Lovis","year":"2017","journal-title":"Vet Parasitol"},{"issue":"39","key":"10.1016\/j.ebiom.2024.105190_bib16","article-title":"Mosquitoes and transmission of malaria parasites - not just vectors","volume":"3","author":"Paul","year":"2004","journal-title":"Malar J"},{"issue":"2","key":"10.1016\/j.ebiom.2024.105190_bib17","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1098\/rsbl.2004.0260","article-title":"Malaria parasite growth is stimulated by mosquito probing","volume":"1","author":"Billingsley","year":"2005","journal-title":"Biol Lett"},{"issue":"1579","key":"10.1016\/j.ebiom.2024.105190_bib18","first-page":"2397","article-title":"Rodent malaria parasites Plasmodium chabaudi and P. vinckei do not increase their rates of gametocytogenesis in response to mosquito probing","volume":"272","author":"Shutler","year":"2005","journal-title":"Proc Biol Sci"},{"issue":"9","key":"10.1016\/j.ebiom.2024.105190_bib19","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1004308","article-title":"Evolution of plastic transmission strategies in avian malaria","volume":"10","author":"Cornet","year":"2014","journal-title":"PLoS Pathog"},{"key":"10.1016\/j.ebiom.2024.105190_bib20","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0040170","article-title":"IgG responses to Anopheles gambiae salivary antigen gSG6 detect variation in exposure to malaria vectors and disease","volume":"7","author":"Stone","year":"2012","journal-title":"PLoS One"},{"issue":"5","key":"10.1016\/j.ebiom.2024.105190_bib21","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0006439","article-title":"Mosquito saliva alone has profound effects on the human immune system","volume":"12","author":"Vogt","year":"2018","journal-title":"PLoS Neglected Trop Dis"},{"issue":"1","key":"10.1016\/j.ebiom.2024.105190_bib22","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/j.actatropica.2007.09.003","article-title":"Seasonal patterns of Plasmodium falciparum gametocyte prevalence and density in a rural population of Burkina Faso","volume":"105","author":"Ou\u00e9draogo","year":"2008","journal-title":"Acta Trop"},{"issue":"4","key":"10.1016\/j.ebiom.2024.105190_bib23","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1016\/S0035-9203(03)90059-9","article-title":"Transmission of Plasmodium falciparum in urban Yaound\u00e9, Cameroon, is seasonal and age-dependent","volume":"97","author":"van der Kolk","year":"2003","journal-title":"Trans R Soc Trop Med Hyg"},{"key":"10.1016\/j.ebiom.2024.105190_bib24","doi-asserted-by":"crossref","first-page":"6159","DOI":"10.1038\/s41467-020-19988-z","article-title":"The transcriptome of circulating sexually committed Plasmodium falciparum ring stage parasites forecasts malaria transmission potential","volume":"11","author":"Prajapati","year":"2020","journal-title":"Nat Commun"},{"key":"10.1016\/j.ebiom.2024.105190_bib25","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1038\/nature12970","article-title":"A\u00a0cascade of DNA-binding proteins for sexual commitment and development in Plasmodium","volume":"507","author":"Sinha","year":"2014","journal-title":"Nature"},{"issue":"6381","key":"10.1016\/j.ebiom.2024.105190_bib26","doi-asserted-by":"crossref","first-page":"1259","DOI":"10.1126\/science.aan6042","article-title":"GDV1 induces sexual commitment of malaria parasites by antagonizing HP1-dependent gene silencing","volume":"359","author":"Filarsky","year":"2018","journal-title":"Science"},{"key":"10.1016\/j.ebiom.2024.105190_bib27","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-018-34078-3","article-title":"Multi-population genomic analysis of malaria parasites indicates local selection and differentiation at the gdv1 locus regulating sexual development","volume":"8","author":"Duffy","year":"2018","journal-title":"Sci Rep"},{"issue":"10","key":"10.1016\/j.ebiom.2024.105190_bib28","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1002964","article-title":"Plasmodium falciparum gametocyte development 1 (Pfgdv1) and gametocytogenesis early gene identification and commitment to sexual development","volume":"8","author":"Eksi","year":"2012","journal-title":"PLoS Pathog"},{"issue":"334","key":"10.1016\/j.ebiom.2024.105190_bib29","article-title":"Specific expression and export of the Plasmodium falciparum Gametocyte EXported Protein-5 marks the gametocyte ring stage","volume":"14","author":"Tib\u00farcio","year":"2015","journal-title":"Malar J"},{"issue":"7","key":"10.1016\/j.ebiom.2024.105190_bib30","doi-asserted-by":"crossref","first-page":"1167","DOI":"10.1093\/infdis\/jix035","article-title":"Initiation of gametocytogenesis at very low parasite density in Plasmodium falciparum infection","volume":"215","author":"Farid","year":"2017","journal-title":"J\u00a0Infect Dis"},{"key":"10.1016\/j.ebiom.2024.105190_bib31","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-021-97456-4","article-title":"Real-time PCR assays for detection and quantification of early P.falciparum gametocyte stages","volume":"11","author":"Gadalla","year":"2021","journal-title":"Sci Rep"},{"issue":"7","key":"10.1016\/j.ebiom.2024.105190_bib32","doi-asserted-by":"crossref","first-page":"1437","DOI":"10.1074\/mcp.M900479-MCP200","article-title":"Protein export marks the early phase of gametocytogenesis of the human malaria parasite Plasmodium falciparum","volume":"9","author":"Silvestrini","year":"2010","journal-title":"Mol Cell Proteomics"},{"issue":"24","key":"10.1016\/j.ebiom.2024.105190_bib33","doi-asserted-by":"crossref","DOI":"10.1126\/sciadv.aaz5057","article-title":"Conditional expression of PfAP2-G for controlled massive sexual conversion in Plasmodium falciparum","volume":"6","author":"Llor\u00e0-Batlle","year":"2020","journal-title":"Sci Adv"},{"key":"10.1016\/j.ebiom.2024.105190_bib34","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-019-50768-y","article-title":"Reporter\u00a0lines based on the gexp02 promoter enable early quantification of sexual conversion rates in the malaria parasite Plasmodium falciparum","volume":"9","author":"Portugaliza","year":"2019","journal-title":"Sci Rep"},{"issue":"2","key":"10.1016\/j.ebiom.2024.105190_bib35","doi-asserted-by":"crossref","DOI":"10.1111\/cmi.13123","article-title":"The PHIST protein GEXP02 targets the host cytoskeleton during sexual development of Plasmodium falciparum","volume":"22","author":"Warncke","year":"2020","journal-title":"Cell Microbiol"},{"issue":"70","key":"10.1016\/j.ebiom.2024.105190_bib36","article-title":"Probing Plasmodium falciparum sexual commitment at the single-cell level","volume":"3","author":"Brancucci","year":"2018","journal-title":"Wellcome Open Res"},{"issue":"12","key":"10.1016\/j.ebiom.2024.105190_bib37","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pcbi.1003392","article-title":"Inferring developmental stage composition from gene expression in human malaria","volume":"9","author":"Joice","year":"2013","journal-title":"PLoS Comput Biol"},{"issue":"1","key":"10.1016\/j.ebiom.2024.105190_bib38","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1016\/j.molbiopara.2005.04.015","article-title":"Genome-wide identification of genes upregulated at the onset of gametocytogenesis in Plasmodium falciparum","volume":"143","author":"Silvestrini","year":"2005","journal-title":"Mol Biochem Parasitol"},{"issue":"6","key":"10.1016\/j.ebiom.2024.105190_bib39","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1016\/j.ijpara.2009.11.006","article-title":"Regulated oligomerisation and molecular interactions of the early gametocyte protein Pfg27 in Plasmodium falciparum sexual differentiation","volume":"40","author":"Camarda","year":"2010","journal-title":"Int J Parasitol"},{"issue":"2","key":"10.1016\/j.ebiom.2024.105190_bib40","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1111\/j.1365-2958.2009.06762.x","article-title":"The Plasmodium falciparum protein Pfg27 is dispensable for gametocyte and gamete production, but contributes to cell integrity during gametocytogenesis","volume":"73","author":"Olivieri","year":"2009","journal-title":"Mol Microbiol"},{"key":"10.1016\/j.ebiom.2024.105190_bib41","doi-asserted-by":"crossref","first-page":"1530","DOI":"10.1038\/ncomms2539","article-title":"Sir2a regulates rDNA transcription and multiplication rate in the human malaria parasite Plasmodium falciparum","volume":"4","author":"Mancio-Silva","year":"2013","journal-title":"Nat Commun"},{"issue":"920","key":"10.1016\/j.ebiom.2024.105190_bib42","article-title":"Hierarchical transcriptional control regulates Plasmodium falciparum sexual differentiation","volume":"20","author":"van Biljon","year":"2019","journal-title":"BMC Genom"},{"issue":"7","key":"10.1016\/j.ebiom.2024.105190_bib43","doi-asserted-by":"crossref","first-page":"1257","DOI":"10.1093\/infdis\/jiaa157","article-title":"Randomized clinical trial to compare Plasmodium falciparum gametocytemia and infectivity after blood-stage or mosquito bite-induced controlled malaria infection","volume":"224","author":"Alkema","year":"2021","journal-title":"J\u00a0Infect Dis"},{"issue":"4","key":"10.1016\/j.ebiom.2024.105190_bib44","doi-asserted-by":"crossref","first-page":"1551","DOI":"10.1172\/JCI98012","article-title":"A\u00a0controlled human malaria infection model enabling evaluation of transmission-blocking interventions","volume":"128","author":"Collins","year":"2018","journal-title":"J\u00a0Clin Invest"},{"issue":"8","key":"10.1016\/j.ebiom.2024.105190_bib45","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0021914","article-title":"A\u00a0pilot randomised trial of induced blood-stage Plasmodium falciparum infections in healthy volunteers for testing efficacy of new antimalarial drugs","volume":"6","author":"McCarthy","year":"2011","journal-title":"PLoS One"},{"key":"10.1016\/j.ebiom.2024.105190_bib46","doi-asserted-by":"crossref","DOI":"10.1136\/bmjopen-2019-030598","article-title":"Investigating the impact of enhanced community case management and monthly screening and treatment on the transmissibility of malaria infections in Burkina Faso: study protocol for a cluster-randomised trial","volume":"9","author":"Collins","year":"2019","journal-title":"BMJ Open"},{"issue":"5","key":"10.1016\/j.ebiom.2024.105190_bib47","first-page":"587","article-title":"Is asymptomatic malaria really asymptomatic? Hematological, vascular and inflammatory effects of asymptomatic malaria parasitemia","volume":"71","author":"De Mast","year":"2015","journal-title":"J\u00a0Infect"},{"issue":"2","key":"10.1016\/j.ebiom.2024.105190_bib48","doi-asserted-by":"crossref","first-page":"280","DOI":"10.4269\/ajtmh.2007.76.280","article-title":"Low prevalence of an acute phase response in asymptomatic children from a malaria-endemic area of Papua New Guinea","volume":"76","author":"Imrie","year":"2007","journal-title":"Am J Trop Med Hyg"},{"issue":"12","key":"10.1016\/j.ebiom.2024.105190_bib49","doi-asserted-by":"crossref","first-page":"2544","DOI":"10.1093\/cid\/ciz740","article-title":"Serologic markers of previous malaria exposure and functional antibodies inhibiting parasite growth are associated with parasite kinetics following a Plasmodium falciparum controlled human infection","volume":"70","author":"Achan","year":"2020","journal-title":"Clin Infect Dis"},{"issue":"10","key":"10.1016\/j.ebiom.2024.105190_bib50","doi-asserted-by":"crossref","DOI":"10.1093\/infdis\/jiz680","article-title":"Plasmodium falciparum gametocyte density and infectivity in peripheral blood and skin tissue of naturally infected parasite carriers in Burkina Faso","volume":"223","author":"Meibalan","year":"2021","journal-title":"J\u00a0Infect Dis"},{"issue":"1","key":"10.1016\/j.ebiom.2024.105190_bib51","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1038\/s41564-018-0291-7","article-title":"Revisiting the initial steps of sexual development in the malaria parasite Plasmodium falciparum","volume":"4","author":"Bancells","year":"2019","journal-title":"Nat Microbiol"},{"issue":"441","key":"10.1016\/j.ebiom.2024.105190_bib52","article-title":"A\u00a0multiplex assay for the sensitive detection and quantification of male and female Plasmodium falciparum gametocytes","volume":"17","author":"Meerstein-Kessel","year":"2018","journal-title":"Malar J"},{"issue":"3","key":"10.1016\/j.ebiom.2024.105190_bib53","doi-asserted-by":"crossref","first-page":"572","DOI":"10.4269\/ajtmh.18-0773","article-title":"Plasmodium falciparum gametocyte enrichment in peripheral blood samples by magnetic fractionation: gametocyte yields and possibilities to reuse columns","volume":"100","author":"Graumans","year":"2019","journal-title":"Am J Trop Med Hyg"},{"issue":"4809","key":"10.1016\/j.ebiom.2024.105190_bib54","doi-asserted-by":"crossref","first-page":"1661","DOI":"10.1126\/science.3299700","article-title":"Genetic analysis of the human malaria parasite Plasmodium falciparum","volume":"236","author":"Walliker","year":"1987","journal-title":"Science"},{"key":"10.1016\/j.ebiom.2024.105190_bib55","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1017\/S003118200005143X","article-title":"Synchronization of Plasmodium falciparum gametocytes using an automated suspension culture system","volume":"93","author":"Ponnudurai","year":"1986","journal-title":"Parasitology"},{"issue":"454","key":"10.1016\/j.ebiom.2024.105190_bib56","article-title":"Strand-specific RNA sequencing in Plasmodium falciparum malaria identifies developmentally regulated long non-coding RNA and circular RNA","volume":"16","author":"Broadbent","year":"2015","journal-title":"BMC Genom"},{"key":"10.1016\/j.ebiom.2024.105190_bib57","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.31549","article-title":"A\u00a0randomized feasibility trial comparing four antimalarial drug regimens to induce Plasmodium falciparum gametocytemia in the controlled human malaria infection model","volume":"7","author":"Reuling","year":"2018","journal-title":"Elife"},{"key":"10.1016\/j.ebiom.2024.105190_bib58","doi-asserted-by":"crossref","DOI":"10.1016\/j.ebiom.2022.104198","article-title":"Plasmodium falciparum sexual conversion rates can be affected by artemisinin-based treatment in naturally infected malaria patients","volume":"83","author":"Portugaliza","year":"2022","journal-title":"eBioMedicine"},{"issue":"1","key":"10.1016\/j.ebiom.2024.105190_bib59","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.cell.2005.01.037","article-title":"Telomeric heterochromatin propagation and histone acetylation control mutually exclusive expression of antigenic variation genes in malaria parasites","volume":"121","author":"Freitas-Junior","year":"2005","journal-title":"Cell"},{"issue":"1","key":"10.1016\/j.ebiom.2024.105190_bib60","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.cell.2005.01.036","article-title":"Heterochromatin silencing and locus repositioning linked to regulation of virulence genes in Plasmodium falciparum","volume":"121","author":"Duraisingh","year":"2005","journal-title":"Cell"},{"key":"10.1016\/j.ebiom.2024.105190_bib61","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1186\/s12936-019-2963-z","article-title":"Differential expression of var subgroups and PfSir2a genes in afebrile Plasmodium falciparum malaria: a matched case-control study","volume":"18","author":"Gupta","year":"2019","journal-title":"Malaria J"},{"issue":"6","key":"10.1016\/j.ebiom.2024.105190_bib62","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0002472","article-title":"Novel peptide marker corresponding to salivary protein gSG6 potentially identifies exposure to Anopheles bites","volume":"3","author":"Poinsignon","year":"2008","journal-title":"PLoS One"}],"container-title":["eBioMedicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2352396424002251?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2352396424002251?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,9,19]],"date-time":"2024-09-19T17:52:30Z","timestamp":1726768350000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2352396424002251"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7]]},"references-count":62,"alternative-id":["S2352396424002251"],"URL":"https:\/\/doi.org\/10.1016\/j.ebiom.2024.105190","relation":{},"ISSN":["2352-3964"],"issn-type":[{"value":"2352-3964","type":"print"}],"subject":[],"published":{"date-parts":[[2024,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Plasmodium falciparum gametocyte production correlates with genetic markers of parasite replication but is not influenced by experimental exposure to mosquito biting","name":"articletitle","label":"Article Title"},{"value":"eBioMedicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ebiom.2024.105190","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Author(s). Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"105190"}}