{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T20:12:33Z","timestamp":1778875953790,"version":"3.51.4"},"reference-count":59,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,10,3]],"date-time":"2024-10-03T00:00:00Z","timestamp":1727913600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100009708","name":"Novo Nordisk Fonden","doi-asserted-by":"publisher","award":["NNF17OC0027594"],"award-info":[{"award-number":["NNF17OC0027594"]}],"id":[{"id":"10.13039\/501100009708","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100009708","name":"Novo Nordisk Fonden","doi-asserted-by":"publisher","award":["NNF14CC0001"],"award-info":[{"award-number":["NNF14CC0001"]}],"id":[{"id":"10.13039\/501100009708","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008392","name":"Sundhed og Sygdom, Det Frie Forskningsr\u00e5d","doi-asserted-by":"publisher","award":["09-069412"],"award-info":[{"award-number":["09-069412"]}],"id":[{"id":"10.13039\/100008392","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010983","name":"Health Research Fund of Central Denmark Region","doi-asserted-by":"publisher","award":["R5-A329"],"award-info":[{"award-number":["R5-A329"]}],"id":[{"id":"10.13039\/501100010983","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010983","name":"Health Research Fund of Central Denmark Region","doi-asserted-by":"publisher","award":["R64-A3264"],"award-info":[{"award-number":["R64-A3264"]}],"id":[{"id":"10.13039\/501100010983","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100012526","name":"University of Aarhus Faculty of Health","doi-asserted-by":"publisher","award":["18290985"],"award-info":[{"award-number":["18290985"]}],"id":[{"id":"10.13039\/100012526","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007420","name":"Danish Medical Association","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100007420","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004836","name":"Independent Research Fund Denmark","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004836","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005747","name":"A.P. M\u00f8ller og Hustru Chastine Mc-Kinney M\u00f8llers Fond til almene Formaal","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005747","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007605","name":"Aarhus Universitet","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007605","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006492","name":"National Institute of Allergy and Infectious Diseases Division of Intramural Research","doi-asserted-by":"publisher","award":["1R01AI125562-01"],"award-info":[{"award-number":["1R01AI125562-01"]}],"id":[{"id":"10.13039\/100006492","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","award":["2016-1840\/124"],"award-info":[{"award-number":["2016-1840\/124"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010767","name":"Innovative Medicines Initiative","doi-asserted-by":"publisher","award":["115881"],"award-info":[{"award-number":["115881"]}],"id":[{"id":"10.13039\/501100010767","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006197","name":"Fonden til L\u00e6gevidenskabens Fremme","doi-asserted-by":"publisher","award":["17-L-0555"],"award-info":[{"award-number":["17-L-0555"]}],"id":[{"id":"10.13039\/501100006197","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003035","name":"Aase og Ejnar Danielsens Fond","doi-asserted-by":"publisher","award":["10-001077"],"award-info":[{"award-number":["10-001077"]}],"id":[{"id":"10.13039\/501100003035","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003035","name":"Aase og Ejnar Danielsens Fond","doi-asserted-by":"publisher","award":["19-10-0080"],"award-info":[{"award-number":["19-10-0080"]}],"id":[{"id":"10.13039\/501100003035","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","thelancet.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["eBioMedicine"],"published-print":{"date-parts":[[2024,11]]},"DOI":"10.1016\/j.ebiom.2024.105406","type":"journal-article","created":{"date-parts":[[2024,10,21]],"date-time":"2024-10-21T16:00:46Z","timestamp":1729526446000},"page":"105406","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["Impact of CCR5\u039432 on the risk of infection, Staphylococcus aureus carriage, and plasma concentrations of chemokines in Danish blood donors"],"prefix":"10.1016","volume":"109","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1881-5673","authenticated-orcid":false,"given":"Khoa Manh","family":"Dinh","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kathrine Agerg\u00e5rd","family":"Kaspersen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Susan","family":"Mikkelsen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9953-9521","authenticated-orcid":false,"given":"Bertram Dalskov","family":"Kjerulff","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jens Kj\u00e6rgaard","family":"Boldsen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mikkel Steen","family":"Petersen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kristoffer S\u00f8lvsten","family":"Burgdorf","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erik","family":"S\u00f8rensen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bitten","family":"Aagaard","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Barbara","family":"Forman-Ankj\u00e6r","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mie Topholm","family":"Bruun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karina","family":"Banasik","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6703-7762","authenticated-orcid":false,"given":"Thomas Folkmann","family":"Hansen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4973-8543","authenticated-orcid":false,"given":"Mette","family":"Nyegaard","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Palle Duun","family":"Rohde","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S\u00f8ren","family":"Brunak","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Henrik","family":"Hjalgrim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5288-3851","authenticated-orcid":false,"given":"Sisse Rye","family":"Ostrowski","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ole Birger","family":"Pedersen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Henrik","family":"Ullum","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lise Tornvig","family":"Erikstrup","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christian","family":"Erikstrup","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"11","key":"10.1016\/j.ebiom.2024.105406_bib1","doi-asserted-by":"crossref","first-page":"1201","DOI":"10.1016\/j.cellsig.2004.04.007","article-title":"Chemokine receptor CCR5: insights into structure, function, and regulation","volume":"16","author":"Oppermann","year":"2004","journal-title":"Cell Signal"},{"issue":"6593","key":"10.1016\/j.ebiom.2024.105406_bib2","doi-asserted-by":"crossref","first-page":"722","DOI":"10.1038\/382722a0","article-title":"Resistance to HIV-1 infection in Caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene","volume":"382","author":"Samson","year":"1996","journal-title":"Nature"},{"issue":"5270","key":"10.1016\/j.ebiom.2024.105406_bib3","doi-asserted-by":"crossref","first-page":"1955","DOI":"10.1126\/science.272.5270.1955","article-title":"CC CKR5: a RANTES, MIP-1, MIP-1 receptor as a fusion cofactor for macrophage-tropic HIV-1","volume":"272","author":"Alkhatib","year":"1996","journal-title":"Science"},{"issue":"6418","key":"10.1016\/j.ebiom.2024.105406_bib4","doi-asserted-by":"crossref","first-page":"978","DOI":"10.1126\/science.362.6418.978","article-title":"Shock greets claim of CRISPR-edited babies","volume":"362","author":"Normile","year":"2018","journal-title":"Science"},{"issue":"3","key":"10.1016\/j.ebiom.2024.105406_bib5","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1093\/hmg\/7.3.399","article-title":"The \u0394ccr5 mutation conferring protection against HIV-1 in Caucasian populations has a single and recent origin in Northeastern Europe","volume":"7","author":"Libert","year":"1998","journal-title":"Hum Mol Genet"},{"issue":"6","key":"10.1016\/j.ebiom.2024.105406_bib6","doi-asserted-by":"crossref","first-page":"1507","DOI":"10.1086\/301867","article-title":"Dating the origin of the CCR5-\u039432 AIDS-resistance allele by the coalescence of haplotypes","volume":"62","author":"Stephens","year":"1998","journal-title":"Am J Hum Genet"},{"issue":"25","key":"10.1016\/j.ebiom.2024.105406_bib7","doi-asserted-by":"crossref","first-page":"15276","DOI":"10.1073\/pnas.2435085100","article-title":"Evaluating plague and smallpox as historical selective pressures for the CCR5- 32 HIV-resistance allele","volume":"100","author":"Galvani","year":"2003","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"4","key":"10.1016\/j.ebiom.2024.105406_bib8","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1038\/sj.gene.6364172","article-title":"Detection of the CCR5-\u039432 HIV resistance gene in Bronze Age skeletons","volume":"6","author":"Hummel","year":"2005","journal-title":"Genes Immun"},{"issue":"7430","key":"10.1016\/j.ebiom.2024.105406_bib9","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1038\/nature11724","article-title":"CCR5 is a receptor for Staphylococcus aureus leukotoxin ED","volume":"493","author":"Alonzo","year":"2012","journal-title":"Nature"},{"issue":"1","key":"10.1016\/j.ebiom.2024.105406_bib10","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1128\/br.27.1.56-71.1963","article-title":"Healthy carriage of Staphylococcus aureus: its prevalence and importance","volume":"27","author":"Williams","year":"1963","journal-title":"Bacteriol Rev"},{"issue":"3","key":"10.1016\/j.ebiom.2024.105406_bib11","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1128\/CMR.10.3.505","article-title":"Nasal carriage of Staphylococcus aureus: epidemiology, underlying mechanisms, and associated risks","volume":"10","author":"Kluytmans","year":"1997","journal-title":"Clin Microbiol Rev"},{"issue":"9","key":"10.1016\/j.ebiom.2024.105406_bib12","doi-asserted-by":"crossref","first-page":"1226","DOI":"10.1086\/533494","article-title":"Changes in the prevalence of nasal colonization with Staphylococcus aureus in the United States, 2001-2004","volume":"197","author":"Gorwitz","year":"2008","journal-title":"J\u00a0Infect Dis"},{"key":"10.1016\/j.ebiom.2024.105406_bib13","doi-asserted-by":"crossref","first-page":"885","DOI":"10.2147\/CLEP.S218637","article-title":"Cohort description: the Danish blood donor Staphylococcus aureus carriage study","volume":"11","author":"Erikstrup","year":"2019","journal-title":"Clin Epidemiol"},{"issue":"3","key":"10.1016\/j.ebiom.2024.105406_bib14","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1128\/CMR.00134-14","article-title":"Staphylococcus aureus infections: epidemiology, pathophysiology, clinical manifestations, and management","volume":"28","author":"Tong","year":"2015","journal-title":"Clin Microbiol Rev"},{"issue":"9435","key":"10.1016\/j.ebiom.2024.105406_bib15","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1016\/S0140-6736(04)16897-9","article-title":"Risk and outcome of nosocomial Staphylococcus aureus bacteraemia in nasal carriers versus non-carriers","volume":"364","author":"Wertheim","year":"2004","journal-title":"Lancet"},{"key":"10.1016\/j.ebiom.2024.105406_bib16","series-title":"DANMAP 2022 - use of antimicrobial agents and occurrence of antimicrobial resistance in bacteria from food animals, food and humans in Denmark. Infectious Disease Preparedness \u2013 bacteria, Parasites and Fungi","author":"danmaporg","year":"2023"},{"issue":"46","key":"10.1016\/j.ebiom.2024.105406_bib17","doi-asserted-by":"crossref","DOI":"10.2807\/1560-7917.ES.2021.26.46.2002094","article-title":"Staphylococcus aureus bloodstream infections: diverging trends of meticillin-resistant and meticillin-susceptible isolates, EU\/EEA, 2005 to 2018","volume":"26","author":"Gagliotti","year":"2021","journal-title":"Euro Surveill"},{"issue":"3","key":"10.1016\/j.ebiom.2024.105406_bib18","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1016\/j.jaci.2010.11.050","article-title":"Interleukins, from 1 to 37, and interferon-\u03b3: receptors, functions, and roles in diseases","volume":"127","author":"Akdis","year":"2011","journal-title":"J\u00a0Allergy Clin Immunol"},{"issue":"1","key":"10.1016\/j.ebiom.2024.105406_bib19","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1006\/cyto.1998.0396","article-title":"Heterozygous defect in HIV-1 coreceptor CCR5 and chemokine production","volume":"11","author":"Yang","year":"1999","journal-title":"Cytokine"},{"issue":"1","key":"10.1016\/j.ebiom.2024.105406_bib20","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.ajhg.2016.11.007","article-title":"Genome-wide association study identifies 27 loci influencing concentrations of circulating cytokines and growth factors","volume":"100","author":"Ahola-Olli","year":"2017","journal-title":"Am J Hum Genet"},{"key":"10.1016\/j.ebiom.2024.105406_bib21","doi-asserted-by":"crossref","first-page":"e162","DOI":"10.1093\/ije\/dyac194","article-title":"Cohort profile: the Danish blood donor study","volume":"52","author":"Erikstrup","year":"2022","journal-title":"Int J Epidemiol"},{"issue":"6","key":"10.1016\/j.ebiom.2024.105406_bib22","doi-asserted-by":"crossref","DOI":"10.1136\/bmjopen-2018-028401","article-title":"DBDS genomic cohort, a prospective and comprehensive resource for integrative and temporal analysis of genetic, environmental and lifestyle factors affecting health of blood donors","volume":"9","author":"Hansen","year":"2019","journal-title":"BMJ Open"},{"issue":"11","key":"10.1016\/j.ebiom.2024.105406_bib23","doi-asserted-by":"crossref","first-page":"1654","DOI":"10.1038\/ng.3964","article-title":"Graphtyper enables population-scale genotyping using pangenome graphs","volume":"49","author":"Eggertsson","year":"2017","journal-title":"Nat Genet"},{"issue":"4","key":"10.1016\/j.ebiom.2024.105406_bib24","doi-asserted-by":"crossref","first-page":"2213","DOI":"10.1093\/genetics\/165.4.2213","article-title":"Modeling linkage disequilibrium and identifying recombination hotspots using single-nucleotide polymorphism data","volume":"165","author":"Li","year":"2003","journal-title":"Genetics"},{"issue":"6","key":"10.1016\/j.ebiom.2024.105406_bib25","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pgen.1000529","article-title":"A\u00a0flexible and accurate genotype imputation method for the next generation of genome-wide association studies","volume":"5","author":"Howie","year":"2009","journal-title":"PLoS Genet"},{"issue":"7 Suppl","key":"10.1016\/j.ebiom.2024.105406_bib26","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1177\/1403494811401482","article-title":"The Danish national patient register","volume":"39","author":"Lynge","year":"2011","journal-title":"Scand J Publ Health"},{"issue":"2","key":"10.1016\/j.ebiom.2024.105406_bib27","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1016\/j.jclinepi.2008.03.005","article-title":"Predictive values of acute coronary syndrome discharge diagnoses differed in the Danish national patient registry","volume":"62","author":"Joensen","year":"2009","journal-title":"J\u00a0Clin Epidemiol"},{"issue":"4","key":"10.1016\/j.ebiom.2024.105406_bib28","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1097\/EDE.0000000000000301","article-title":"Obesity and risk of infection: results from the Danish blood donor study","volume":"26","author":"Kaspersen","year":"2015","journal-title":"Epidemiology"},{"issue":"7 Suppl","key":"10.1016\/j.ebiom.2024.105406_bib29","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1177\/1403494810394717","article-title":"The Danish national prescription registry","volume":"39","author":"Kildemoes","year":"2011","journal-title":"Scand J Public Health"},{"issue":"12","key":"10.1016\/j.ebiom.2024.105406_bib30","doi-asserted-by":"crossref","first-page":"1820","DOI":"10.1086\/599119","article-title":"Reclassification of Staphylococcus aureus nasal carriage types","volume":"199","author":"van Belkum","year":"2009","journal-title":"J\u00a0Infect Dis"},{"issue":"1","key":"10.1016\/j.ebiom.2024.105406_bib31","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1038\/s43856-024-00474-2","article-title":"Lifestyle and demographic associations with 47 inflammatory and vascular stress biomarkers in 9876 blood donors","volume":"4","author":"Kjerulff","year":"2024","journal-title":"Commun Med"},{"key":"10.1016\/j.ebiom.2024.105406_bib32","series-title":"A\u00a0new method of classifying prognostic comorbidity in longitudinal studies: development and validation","author":"Charlson","year":"1987"},{"issue":"2","key":"10.1016\/j.ebiom.2024.105406_bib33","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1086\/524691","article-title":"Genetic deficiency of chemokine receptor CCR5 is a strong risk factor for symptomatic West Nile virus infection: a meta-analysis of 4 cohorts in the US epidemic","volume":"197","author":"Lim","year":"2008","journal-title":"J\u00a0Infect Dis"},{"issue":"6","key":"10.1016\/j.ebiom.2024.105406_bib34","doi-asserted-by":"crossref","first-page":"1545","DOI":"10.1016\/j.jaci.2007.02.038","article-title":"CCR5\u039432 mutation, Mycoplasma pneumoniae infection, and asthma","volume":"119","author":"Ungv\u00e1ri","year":"2007","journal-title":"J\u00a0Allergy Clin Immunol"},{"issue":"8","key":"10.1016\/j.ebiom.2024.105406_bib35","doi-asserted-by":"crossref","first-page":"2074","DOI":"10.1099\/vir.0.000165","article-title":"CCR5 deficiency predisposes to fatal outcome in influenza virus infection","volume":"96","author":"Pozo","year":"2015","journal-title":"J\u00a0Gen Virol"},{"issue":"6","key":"10.1016\/j.ebiom.2024.105406_bib36","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1097\/MAJ.0b013e3181ee6a62","article-title":"Functional CCR5 receptor protects patients with arthritis from high synovial burden of infecting Chlamydia trachomatis","volume":"340","author":"G\u00e9rard","year":"2010","journal-title":"Am J Med Sci"},{"key":"10.1016\/j.ebiom.2024.105406_bib37","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/j.meegid.2015.01.012","article-title":"A\u00a0new look at osteomyelitis development \u2013 focus on CCR5delta 32. Study in patients from Northeast Brazil","volume":"31","author":"De Souza","year":"2015","journal-title":"Infect Genet Evol"},{"issue":"6","key":"10.1016\/j.ebiom.2024.105406_bib38","doi-asserted-by":"crossref","first-page":"924","DOI":"10.1086\/655901","article-title":"Are host genetics the predominant determinant of persistent nasal Staphylococcus aureus carriage in humans?","volume":"202","author":"Ruimy","year":"2010","journal-title":"J\u00a0Infect Dis"},{"issue":"5","key":"10.1016\/j.ebiom.2024.105406_bib39","doi-asserted-by":"crossref","first-page":"2424","DOI":"10.1128\/IAI.68.5.2424-2430.2000","article-title":"Interleukin-4 and interleukin-10 are involved in host resistance to Staphylococcus aureus infection through regulation of gamma interferon","volume":"68","author":"Sasaki","year":"2000","journal-title":"Infect Immun"},{"issue":"9","key":"10.1016\/j.ebiom.2024.105406_bib40","doi-asserted-by":"crossref","first-page":"1244","DOI":"10.1086\/533501","article-title":"Host polymorphisms in interleukin 4, complement factor H, and C-reactive protein associated with nasal carriage of Staphylococcus aureus and occurrence of boils","volume":"197","author":"Emonts","year":"2008","journal-title":"J\u00a0Infect Dis"},{"issue":"12\u201313","key":"10.1016\/j.ebiom.2024.105406_bib41","doi-asserted-by":"crossref","first-page":"1471","DOI":"10.1016\/j.micinf.2007.08.003","article-title":"The role of human innate immune factors in nasal colonization by Staphylococcus aureus","volume":"9","author":"van Belkum","year":"2007","journal-title":"Microb Infect"},{"issue":"10","key":"10.1016\/j.ebiom.2024.105406_bib42","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0026198","article-title":"Nasopharyngeal bacterial colonization and gene polymorphisms of mannose-binding lectin and toll-like receptors 2 and 4 in infants","volume":"6","author":"Vuononvirta","year":"2011","journal-title":"PLoS One"},{"issue":"7","key":"10.1016\/j.ebiom.2024.105406_bib43","doi-asserted-by":"crossref","first-page":"2658","DOI":"10.1128\/IAI.00101-11","article-title":"Persistent nasal carriage of Staphylococcus aureus is associated with deficient induction of human \u03b2-Defensin 3 after Sterile wounding of healthy skin in\u00a0vivo","volume":"79","author":"Zanger","year":"2011","journal-title":"Infect Immun"},{"issue":"6","key":"10.1016\/j.ebiom.2024.105406_bib44","doi-asserted-by":"crossref","first-page":"814","DOI":"10.1086\/506367","article-title":"Staphylococcus aureus nasal carriage is associated with glucocorticoid receptor gene polymorphisms","volume":"194","author":"van den Akker","year":"2006","journal-title":"J\u00a0Infect Dis"},{"issue":"4","key":"10.1016\/j.ebiom.2024.105406_bib45","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1007\/s10096-011-1331-x","article-title":"Staphylococcus aureus nasal carriage is associated with serum 25-hydroxyvitamin D levels, gender and smoking status. The Troms\u00f8 Staph and Skin Study","volume":"31","author":"Olsen","year":"2012","journal-title":"Eur J Clin Microbiol Infect Dis"},{"issue":"1","key":"10.1016\/j.ebiom.2024.105406_bib46","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1471-2334-14-83","article-title":"A\u00a0genome-wide association study of variants associated with acquisition of Staphylococcus aureus bacteremia in a healthcare setting","volume":"14","author":"Nelson","year":"2014","journal-title":"BMC Infect Dis"},{"key":"10.1016\/j.ebiom.2024.105406_bib47","doi-asserted-by":"crossref","DOI":"10.3389\/fgene.2014.00125","article-title":"Genome wide association study of SNP-, gene-, and pathway-based approaches to identify genes influencing susceptibility to Staphylococcus aureus infections","volume":"5","author":"Ye","year":"2014","journal-title":"Front Genet"},{"issue":"5","key":"10.1016\/j.ebiom.2024.105406_bib48","doi-asserted-by":"crossref","first-page":"816","DOI":"10.1093\/infdis\/jiv483","article-title":"Polymorphisms in HLA class II genes are associated with susceptibility to Staphylococcus aureus infection in a white population","volume":"213","author":"DeLorenze","year":"2016","journal-title":"J\u00a0Infect Dis"},{"issue":"10","key":"10.1016\/j.ebiom.2024.105406_bib49","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pgen.1007667","article-title":"Human genetic variation in GLS2 is associated with development of complicated Staphylococcus aureus bacteremia","volume":"14","author":"Scott","year":"2018","journal-title":"PLoS Genet"},{"issue":"11","key":"10.1016\/j.ebiom.2024.105406_bib50","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0142130","article-title":"Genome-wide association study of Staphylococcus aureus carriage in a community-based sample of Mexican-Americans in starr county, Texas","volume":"10","author":"Brown","year":"2015","journal-title":"PLoS One"},{"issue":"8","key":"10.1016\/j.ebiom.2024.105406_bib51","doi-asserted-by":"crossref","first-page":"1178","DOI":"10.1093\/infdis\/jis491","article-title":"Influence of host genetics and environment on nasal carriage of Staphylococcus aureus in Danish middle-aged and elderly twins","volume":"206","author":"Andersen","year":"2012","journal-title":"J\u00a0Infect Dis"},{"issue":"1","key":"10.1016\/j.ebiom.2024.105406_bib52","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1186\/s13063-016-1388-z","article-title":"Danish study of non-invasive testing in Coronary Artery Disease (Dan-NICAD): study protocol for a randomised controlled trial","volume":"17","author":"Nissen","year":"2016","journal-title":"Trials"},{"issue":"suppl_1","key":"10.1016\/j.ebiom.2024.105406_bib53","doi-asserted-by":"crossref","first-page":"S82","DOI":"10.1309\/M6U4B8L6TNAK4G9L","article-title":"Chemokines and their receptors","volume":"123","author":"Locati","year":"2005","journal-title":"Pathol Patterns Rev"},{"issue":"1","key":"10.1016\/j.ebiom.2024.105406_bib54","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1084\/jem.188.1.157","article-title":"The coordinated action of CC chemokines in the lung orchestrates allergic inflammation and airway hyperresponsiveness","volume":"188","author":"Gonzalo","year":"1998","journal-title":"J\u00a0Exp Med"},{"issue":"9186","key":"10.1016\/j.ebiom.2024.105406_bib55","doi-asserted-by":"crossref","first-page":"1264","DOI":"10.1016\/S0140-6736(99)03425-X","article-title":"Association of CCR5 delta32 with reduced risk of asthma","volume":"354","author":"Hall","year":"1999","journal-title":"Lancet"},{"issue":"3","key":"10.1016\/j.ebiom.2024.105406_bib56","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1093\/hmg\/7.3.399","article-title":"The deltaccr5 mutation conferring protection against HIV-1 in Caucasian populations has a single and recent origin in Northeastern Europe","volume":"7","author":"Libert","year":"1998","journal-title":"Hum Mol Genet"},{"issue":"1","key":"10.1016\/j.ebiom.2024.105406_bib57","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1016\/j.atherosclerosis.2015.07.031","article-title":"The impact of CCR5-\u039432 deletion on C-reactive protein levels and cardiovascular disease: results from the Danish blood donor study","volume":"242","author":"Dinh","year":"2015","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.ebiom.2024.105406_bib58","doi-asserted-by":"crossref","first-page":"563","DOI":"10.2147\/CLEP.S179083","article-title":"The Danish health care system and epidemiological research: from health care contacts to database records","volume":"11","author":"Schmidt","year":"2019","journal-title":"Clin Epidemiol"},{"issue":"3","key":"10.1016\/j.ebiom.2024.105406_bib59","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/j.diagmicrobio.2004.03.009","article-title":"Prevalence of genes encoding for members of the staphylococcal leukotoxin family among clinical isolates of Staphylococcus aureus","volume":"49","author":"Von Eiff","year":"2004","journal-title":"Diagn Microbiol Infect Dis"}],"container-title":["eBioMedicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2352396424004420?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2352396424004420?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T19:37:34Z","timestamp":1778873854000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2352396424004420"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11]]},"references-count":59,"alternative-id":["S2352396424004420"],"URL":"https:\/\/doi.org\/10.1016\/j.ebiom.2024.105406","relation":{},"ISSN":["2352-3964"],"issn-type":[{"value":"2352-3964","type":"print"}],"subject":[],"published":{"date-parts":[[2024,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Impact of CCR5\u039432 on the risk of infection, Staphylococcus aureus carriage, and plasma concentrations of chemokines in Danish blood donors","name":"articletitle","label":"Article Title"},{"value":"eBioMedicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ebiom.2024.105406","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Author(s). Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"105406"}}