{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T21:47:38Z","timestamp":1740174458669,"version":"3.37.3"},"reference-count":10,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,10,24]],"date-time":"2024-10-24T00:00:00Z","timestamp":1729728000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100016017","name":"Duke-NUS Medical School","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100016017","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["thelancet.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["eBioMedicine"],"published-print":{"date-parts":[[2024,11]]},"DOI":"10.1016\/j.ebiom.2024.105445","type":"journal-article","created":{"date-parts":[[2024,11,6]],"date-time":"2024-11-06T20:11:46Z","timestamp":1730923906000},"page":"105445","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Evolving vaccine discovery and development pathways for emerging pathogens"],"prefix":"10.1016","volume":"109","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5098-1044","authenticated-orcid":false,"given":"Ashley L.","family":"St. John","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eng Eong","family":"Ooi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ebiom.2024.105445_bib1","doi-asserted-by":"crossref","DOI":"10.1038\/s41591-024-03278-y","article-title":"SARS-CoV-2-specific plasma cells are not durably established in the bone marrow long-lived compartment after mRNA vaccination","author":"Nguyen","year":"2024","journal-title":"Nat Med"},{"issue":"25","key":"10.1016\/j.ebiom.2024.105445_bib2","doi-asserted-by":"crossref","first-page":"4826","DOI":"10.1016\/j.cell.2022.10.023","article-title":"A\u00a0Zika virus-specific IgM elicited in pregnancy exhibits ultrapotent neutralization","volume":"185","author":"Singh","year":"2022","journal-title":"Cell"},{"issue":"5","key":"10.1016\/j.ebiom.2024.105445_bib3","doi-asserted-by":"crossref","first-page":"1373","DOI":"10.1038\/s41591-024-02962-3","article-title":"Correlates of protection against symptomatic SARS-CoV-2 in vaccinated children","volume":"30","author":"Zhong","year":"2024","journal-title":"Nat Med"},{"issue":"10","key":"10.1016\/j.ebiom.2024.105445_bib4","doi-asserted-by":"crossref","first-page":"1711","DOI":"10.1038\/s41590-023-01613-y","article-title":"Prior vaccination promotes early activation of memory T cells and enhances immune responses during SARS-CoV-2 breakthrough infection","volume":"24","author":"Painter","year":"2023","journal-title":"Nat Immunol"},{"issue":"18","key":"10.1016\/j.ebiom.2024.105445_bib5","doi-asserted-by":"crossref","DOI":"10.1172\/JCI169251","article-title":"NKT cells promote Th1 immune bias to dengue virus that governs long-term protective antibody dynamics","volume":"134","author":"Choi","year":"2024","journal-title":"J\u00a0Clin Invest"},{"issue":"27","key":"10.1016\/j.ebiom.2024.105445_bib6","doi-asserted-by":"crossref","first-page":"4042","DOI":"10.1016\/j.vaccine.2023.04.013","article-title":"Promises and challenges of mucosal COVID-19 vaccines","volume":"41","author":"Rathore","year":"2023","journal-title":"Vaccine"},{"issue":"1","key":"10.1016\/j.ebiom.2024.105445_bib7","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1080\/14760584.2024.2331065","article-title":"The durability of vaccine-induced protection: an overview","volume":"23","author":"Vashishtha","year":"2024","journal-title":"Expert Rev Vaccines"},{"issue":"695","key":"10.1016\/j.ebiom.2024.105445_bib8","doi-asserted-by":"crossref","DOI":"10.1126\/scitranslmed.adg7404","article-title":"Broadly neutralizing antibodies against sarbecoviruses generated by immunization of macaques with an AS03-adjuvanted COVID-19 vaccine","volume":"15","author":"Feng","year":"2023","journal-title":"Sci Transl Med"},{"issue":"3","key":"10.1016\/j.ebiom.2024.105445_bib9","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1038\/s41577-022-00753-w","article-title":"Strategies for HIV-1 vaccines that induce broadly neutralizing antibodies","volume":"23","author":"Haynes","year":"2023","journal-title":"Nat Rev Immunol"},{"issue":"7891","key":"10.1016\/j.ebiom.2024.105445_bib10","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1038\/s41586-021-04186-8","article-title":"Pre-existing polymerase-specific T cells expand in abortive seronegative SARS-CoV-2","volume":"601","author":"Swadling","year":"2022","journal-title":"Nature"}],"container-title":["eBioMedicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S235239642400481X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S235239642400481X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,11,20]],"date-time":"2024-11-20T00:33:33Z","timestamp":1732062813000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S235239642400481X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11]]},"references-count":10,"alternative-id":["S235239642400481X"],"URL":"https:\/\/doi.org\/10.1016\/j.ebiom.2024.105445","relation":{},"ISSN":["2352-3964"],"issn-type":[{"type":"print","value":"2352-3964"}],"subject":[],"published":{"date-parts":[[2024,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Evolving vaccine discovery and development pathways for emerging pathogens","name":"articletitle","label":"Article Title"},{"value":"eBioMedicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ebiom.2024.105445","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"simple-article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"105445"}}