{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T19:35:41Z","timestamp":1792438541773,"version":"4.5.0"},"reference-count":34,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,11,21]],"date-time":"2024-11-21T00:00:00Z","timestamp":1732147200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["thelancet.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["eBioMedicine"],"published-print":{"date-parts":[[2025,1]]},"DOI":"10.1016\/j.ebiom.2024.105489","type":"journal-article","created":{"date-parts":[[2024,12,9]],"date-time":"2024-12-09T12:22:12Z","timestamp":1733746932000},"page":"105489","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":13,"special_numbering":"C","title":["Post-treatment duration of positivity for standard and ultra-sensitive Plasmodium falciparum antigen-based rapid diagnostic tests, a cohort study from a low-endemic setting in Namibia"],"prefix":"10.1016","volume":"111","author":[{"given":"Henry","family":"Ntuku","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brooke","family":"Whittemore","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucille","family":"Dausab","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ihn Kyung","family":"Jang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Allison","family":"Golden","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William","family":"Sheahan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xue","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hannah","family":"Slater","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gonzalo J.","family":"Domingo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Smita","family":"Das","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elias","family":"Duarte","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lydia","family":"Eloff","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Teun","family":"Bousema","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kjerstin","family":"Lanke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cara Smith","family":"Gueye","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisa M.","family":"Prach","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jaishree","family":"Raman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Petrina","family":"Uusiku","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stark","family":"Katokele","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roly","family":"Gosling","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bryan","family":"Greenhouse","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Davis","family":"Mumbengegwi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1217-2742","authenticated-orcid":false,"given":"Michelle S.","family":"Hsiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ebiom.2024.105489_bib1","series-title":"Guidelines for the treatment of malaria","year":"2015"},{"key":"10.1016\/j.ebiom.2024.105489_bib2","series-title":"Malaria diagnostics technology and market landscape","year":"2016"},{"key":"10.1016\/j.ebiom.2024.105489_bib3","doi-asserted-by":"crossref","DOI":"10.1016\/j.eclinm.2023.102058","article-title":"Comparing SARS-CoV-2 testing positivity rates and COVID-19 impact among different isolation strategies: a rapid systematic review and a modelling study","volume":"61","author":"Gao","year":"2023","journal-title":"EClinicalMedicine"},{"key":"10.1016\/j.ebiom.2024.105489_bib4","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.29198","article-title":"Quantifying the contribution of Plasmodium falciparum malaria to febrile illness amongst African children","volume":"6","author":"Dalrymple","year":"2017","journal-title":"Elife"},{"issue":"1","key":"10.1016\/j.ebiom.2024.105489_bib5","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1128\/CMR.15.1.66-78.2002","article-title":"Rapid diagnostic tests for malaria parasites","volume":"15","author":"Moody","year":"2002","journal-title":"Clin Microbiol Rev"},{"key":"10.1016\/j.ebiom.2024.105489_bib6","article-title":"Rapid diagnostic tests for diagnosing uncomplicated P. falciparum malaria in endemic countries","volume":"7","author":"Abba","year":"2011","journal-title":"Cochrane Database Syst Rev"},{"issue":"1","key":"10.1016\/j.ebiom.2024.105489_bib7","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1186\/s12936-023-04670-8","article-title":"Testing and treatment for malaria elimination: a systematic review","volume":"22","author":"Newby","year":"2023","journal-title":"Malar J"},{"issue":"7580","key":"10.1016\/j.ebiom.2024.105489_bib8","doi-asserted-by":"crossref","first-page":"S86","DOI":"10.1038\/nature16039","article-title":"Comparison of diagnostics for the detection of asymptomatic Plasmodium falciparum infections to inform control and elimination strategies","volume":"528","author":"Wu","year":"2015","journal-title":"Nature"},{"issue":"5","key":"10.1016\/j.ebiom.2024.105489_bib9","doi-asserted-by":"crossref","first-page":"1540","DOI":"10.4269\/ajtmh.17-0245","article-title":"Performance of a high-sensitivity rapid diagnostic test for Plasmodium falciparum malaria in asymptomatic individuals from Uganda and Myanmar and naive human challenge infections","volume":"97","author":"Das","year":"2017","journal-title":"Am J Trop Med Hyg"},{"issue":"2","key":"10.1016\/j.ebiom.2024.105489_bib10","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/S0035-9203(01)90156-7","article-title":"Persistence of Plasmodium falciparum HRP-2 in successfully treated acute falciparum malaria","volume":"95","author":"Mayxay","year":"2001","journal-title":"Trans R Soc Trop Med Hyg"},{"issue":"2","key":"10.1016\/j.ebiom.2024.105489_bib11","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1016\/j.pt.2019.12.004","article-title":"HRP2: transforming malaria diagnosis, but with caveats","volume":"36","author":"Poti","year":"2020","journal-title":"Trends Parasitol"},{"key":"10.1016\/j.ebiom.2024.105489_bib12","article-title":"Global risk of selection and spread of Plasmodium falciparum histidine-rich protein 2 and 3 gene deletions","author":"Watson","year":"2024","journal-title":"medRxiv"},{"issue":"3","key":"10.1016\/j.ebiom.2024.105489_bib13","doi-asserted-by":"crossref","first-page":"462","DOI":"10.3201\/eid2403.171723","article-title":"Major threat to malaria control programs by Plasmodium falciparum lacking histidine-rich protein 2, Eritrea","volume":"24","author":"Berhane","year":"2018","journal-title":"Emerg Infect Dis"},{"issue":"10","key":"10.1016\/j.ebiom.2024.105489_bib14","doi-asserted-by":"crossref","first-page":"1289","DOI":"10.1038\/s41564-021-00962-4","article-title":"Plasmodium falciparum is evolving to escape malaria rapid diagnostic tests in Ethiopia","volume":"6","author":"Feleke","year":"2021","journal-title":"Nat Microbiol"},{"issue":"1","key":"10.1016\/j.ebiom.2024.105489_bib15","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1186\/s12936-018-2626-5","article-title":"Subpatent malaria in a low transmission African setting: a cross-sectional study using rapid diagnostic testing (RDT) and loop-mediated isothermal amplification (LAMP) from Zambezi region, Namibia","volume":"17","author":"McCreesh","year":"2018","journal-title":"Malar J"},{"issue":"1","key":"10.1016\/j.ebiom.2024.105489_bib16","doi-asserted-by":"crossref","DOI":"10.1128\/JCM.00948-18","article-title":"Simultaneous quantification of Plasmodium antigens and host factor C-reactive protein in asymptomatic individuals with confirmed malaria by use of a novel multiplex immunoassay","volume":"57","author":"Jang","year":"2019","journal-title":"J\u00a0Clin Microbiol"},{"issue":"3","key":"10.1016\/j.ebiom.2024.105489_bib17","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pmed.1001788","article-title":"Ultra-sensitive detection of Plasmodium falciparum by amplification of multi-copy subtelomeric targets","volume":"12","author":"Hofmann","year":"2015","journal-title":"PLoS Med"},{"issue":"3","key":"10.1016\/j.ebiom.2024.105489_bib18","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1016\/j.parint.2014.09.006","article-title":"Improved detection of malaria cases in island settings of Vanuatu and Kenya by PCR that targets the Plasmodium mitochondrial cytochrome c oxidase III (cox3) gene","volume":"64","author":"Isozumi","year":"2015","journal-title":"Parasitol Int"},{"issue":"1","key":"10.1016\/j.ebiom.2024.105489_bib19","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1186\/s12936-018-2584-y","article-title":"A\u00a0multiplex assay for the sensitive detection and quantification of male and female Plasmodium falciparum gametocytes","volume":"17","author":"Meerstein-Kessel","year":"2018","journal-title":"Malar J"},{"issue":"1","key":"10.1016\/j.ebiom.2024.105489_bib20","doi-asserted-by":"crossref","first-page":"188","DOI":"10.4269\/ajtmh.16-0893","article-title":"Molecular markers for sensitive detection of Plasmodium falciparum asexual stage parasites and their application in a malaria clinical trial","volume":"97","author":"Tadesse","year":"2017","journal-title":"Am J Trop Med Hyg"},{"key":"10.1016\/j.ebiom.2024.105489_bib21","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.59872","article-title":"Sex-based differences in clearance of chronic Plasmodium falciparum infection","volume":"9","author":"Briggs","year":"2020","journal-title":"Elife"},{"issue":"1","key":"10.1016\/j.ebiom.2024.105489_bib22","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1186\/s12936-019-2911-y","article-title":"Absence of kelch13 artemisinin resistance markers but strong selection for lumefantrine-tolerance molecular markers following 18 years of artemisinin-based combination therapy use in Mpumalanga Province, South Africa (2001-2018)","volume":"18","author":"Raman","year":"2019","journal-title":"Malar J"},{"issue":"1","key":"10.1016\/j.ebiom.2024.105489_bib23","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1186\/s12936-018-2371-9","article-title":"How long do rapid diagnostic tests remain positive after anti-malarial treatment?","volume":"17","author":"Dalrymple","year":"2018","journal-title":"Malar J"},{"issue":"1","key":"10.1016\/j.ebiom.2024.105489_bib24","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1186\/s12936-022-04387-0","article-title":"Persistence of Plasmodium falciparum HRP-2 antigenaemia after artemisinin combination therapy is not associated with gametocytes","volume":"21","author":"Oulton","year":"2022","journal-title":"Malar J"},{"issue":"1","key":"10.1016\/j.ebiom.2024.105489_bib25","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1186\/s12936-020-03389-0","article-title":"Ultra-sensitive RDT performance and antigen dynamics in a high-transmission Plasmodium falciparum setting in Mali","volume":"19","author":"Reichert","year":"2020","journal-title":"Malar J"},{"key":"10.1016\/j.ebiom.2024.105489_bib26","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1186\/1475-2875-8-211","article-title":"PfHRP2 and PfLDH antigen detection for monitoring the efficacy of artemisinin-based combination therapy (ACT) in the treatment of uncomplicated falciparum malaria","volume":"8","author":"Houze","year":"2009","journal-title":"Malar J"},{"issue":"1","key":"10.1016\/j.ebiom.2024.105489_bib27","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1186\/s12936-021-03783-2","article-title":"Assessing field performance of ultrasensitive rapid diagnostic tests for malaria: a systematic review and meta-analysis","volume":"20","author":"Danwang","year":"2021","journal-title":"Malar J"},{"issue":"9","key":"10.1016\/j.ebiom.2024.105489_bib28","doi-asserted-by":"crossref","DOI":"10.1128\/aac.00002-22","article-title":"Persistence of residual submicroscopic P. Falciparum parasitemia following treatment of artemether-lumefantrine in ethio-Sudan border, Western Ethiopia","volume":"66","author":"Tadele","year":"2022","journal-title":"Antimicrob Agents Chemother"},{"issue":"5","key":"10.1016\/j.ebiom.2024.105489_bib29","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1093\/infdis\/jix622","article-title":"Posttreatment HRP2 clearance in patients with uncomplicated Plasmodium falciparum malaria","volume":"217","author":"Plucinski","year":"2018","journal-title":"J\u00a0Infect Dis"},{"key":"10.1016\/j.ebiom.2024.105489_bib30","series-title":"Methods for surveillance of antimalarial drug efficacy","year":"2009"},{"issue":"1","key":"10.1016\/j.ebiom.2024.105489_bib31","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1186\/s12936-022-04245-z","article-title":"The in-vivo dynamics of Plasmodium falciparum HRP2: implications for the use of rapid diagnostic tests in malaria elimination","volume":"21","author":"Marquart","year":"2022","journal-title":"Malar J"},{"issue":"1","key":"10.1016\/j.ebiom.2024.105489_bib32","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1093\/molbev\/msaa225","article-title":"Evaluating the performance of malaria genetics for inferring changes in transmission intensity using transmission modeling","volume":"38","author":"Watson","year":"2021","journal-title":"Mol Biol Evol"},{"issue":"10233","key":"10.1016\/j.ebiom.2024.105489_bib33","doi-asserted-by":"crossref","first-page":"1361","DOI":"10.1016\/S0140-6736(20)30470-0","article-title":"Effectiveness of reactive focal mass drug administration and reactive focal vector control to reduce malaria transmission in the low malaria-endemic setting of Namibia: a cluster-randomised controlled, open-label, two-by-two factorial design trial","volume":"395","author":"Hsiang","year":"2020","journal-title":"Lancet"},{"issue":"5","key":"10.1016\/j.ebiom.2024.105489_bib34","doi-asserted-by":"crossref","first-page":"956","DOI":"10.4269\/ajtmh.24-0003","article-title":"Analytical sensitivity analysis and clinical impact modeling of Rapigen rapid diagnostics tests for malaria","volume":"111","author":"Golden","year":"2024","journal-title":"Am J Trop Med Hyg"}],"container-title":["eBioMedicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2352396424005255?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2352396424005255?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,1,14]],"date-time":"2025-01-14T03:08:54Z","timestamp":1736824134000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2352396424005255"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1]]},"references-count":34,"alternative-id":["S2352396424005255"],"URL":"https:\/\/doi.org\/10.1016\/j.ebiom.2024.105489","relation":{},"ISSN":["2352-3964"],"issn-type":[{"value":"2352-3964","type":"print"}],"subject":[],"published":{"date-parts":[[2025,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Post-treatment duration of positivity for standard and ultra-sensitive Plasmodium falciparum antigen-based rapid diagnostic tests, a cohort study from a low-endemic setting in Namibia","name":"articletitle","label":"Article Title"},{"value":"eBioMedicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ebiom.2024.105489","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"105489"}}