{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,12]],"date-time":"2025-11-12T00:11:38Z","timestamp":1762906298629,"version":"3.45.0"},"reference-count":14,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,1,18]],"date-time":"2021-01-18T00:00:00Z","timestamp":1610928000000},"content-version":"vor","delay-in-days":17,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Epilepsy & Behavior Reports"],"published-print":{"date-parts":[[2021]]},"DOI":"10.1016\/j.ebr.2021.100432","type":"journal-article","created":{"date-parts":[[2021,1,31]],"date-time":"2021-01-31T01:27:30Z","timestamp":1612056450000},"page":"100432","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"special_numbering":"C","title":["Characterizing the phenotype of drug-resistant childhood epilepsy associated with leukemia: A case series"],"prefix":"10.1016","volume":"15","author":[{"given":"Elham","family":"Abushanab","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elia","family":"Pestana Knight","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahsan N.","family":"Moosa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"8","key":"10.1016\/j.ebr.2021.100432_b0005","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1111\/j.1528-1157.1995.tb01622.x","article-title":"Prognosis and treatment of eizures in children with acute lymphoblastic leukemia","volume":"36","author":"Maytal","year":"1995","journal-title":"Epilepsia"},{"issue":"6","key":"10.1016\/j.ebr.2021.100432_b0010","doi-asserted-by":"crossref","first-page":"1063","DOI":"10.3109\/10428191003754608","article-title":"Central nervous system complications during treatment of acute lymphoblastic leukemia in a single pediatric institution","volume":"51","author":"Parasole","year":"2010","journal-title":"Leuk. Lymphoma"},{"issue":"1","key":"10.1016\/j.ebr.2021.100432_b0015","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/0887-8994(96)00091-4","article-title":"Lennox-Gastaut syndrome associated with leukoencephalopathy","volume":"15","author":"Mitsufuji","year":"1996","journal-title":"Pediatr. Neurol."},{"issue":"6","key":"10.1016\/j.ebr.2021.100432_b0020","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1177\/08830738030180060701","article-title":"Atonic seizures in survivors of childhood cancer","volume":"18","author":"Khan","year":"2003","journal-title":"J. Child Neurol."},{"issue":"4","key":"10.1016\/j.ebr.2021.100432_b0025","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1016\/j.seizure.2008.10.008","article-title":"Intractable epilepsy in patients treated for childhood acute lymphocytic leukemia","volume":"18","author":"Fasano","year":"2009","journal-title":"Seizure"},{"issue":"4","key":"10.1016\/j.ebr.2021.100432_b0030","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1684\/epd.2016.0879","article-title":"Drug-resistant epilepsy after treatment for childhood acute lymphocytic leukaemia: from focal epilepsy to Lennox-Gastaut syndrome","volume":"18","author":"Gonz\u00e1lez-Ot\u00e1rula","year":"2016","journal-title":"Epileptic Disord."},{"key":"10.1016\/j.ebr.2021.100432_b0035","doi-asserted-by":"crossref","DOI":"10.1684\/j.1950-6945.2001.tb00394.x","article-title":"Pathogenesis of Lennox-Gastaut syndrome: Considerations and hypotheses","author":"Blume","year":"2001","journal-title":"Epileptic Disord."},{"issue":"1","key":"10.1016\/j.ebr.2021.100432_b0040","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1046\/j.1528-1157.2003.20302.x","article-title":"Mesial temporal sclerosis in acute childhood leukemias","volume":"44","author":"Goyal","year":"2003","journal-title":"Epilepsia"},{"issue":"1","key":"10.1016\/j.ebr.2021.100432_b0045","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/j.ebcr.2012.12.001","article-title":"Surgical treatment of refractory epilepsy after chemotherapy in two children with leukemia","volume":"1","author":"Leng","year":"2013","journal-title":"Epilepsy Behav. Case Rep."},{"key":"10.1016\/j.ebr.2021.100432_b0050","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/j.ebcr.2018.05.001","article-title":"Drug resistant epilepsy with mesial temporal sclerosis as possible late neurological complication in two AML survivors after stem cell transplantation","volume":"10","author":"Yam","year":"2018","journal-title":"Epilepsy Behav. Case Rep."},{"issue":"1\u20132","key":"10.1016\/j.ebr.2021.100432_b0055","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1159\/000069773","article-title":"Biochemical and clinical aspects of methotrexate neurotoxicity","volume":"49","author":"Vezmar","year":"2003","journal-title":"Chemotherapy"},{"issue":"4","key":"10.1016\/j.ebr.2021.100432_b0060","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1016\/j.pediatrneurol.2008.10.022","article-title":"Mesial temporal sclerosis associated with methotrexate-induced leukoencephalopathy","volume":"40","author":"Hamamoto","year":"2009","journal-title":"Pediatr. Neurol."},{"issue":"1","key":"10.1016\/j.ebr.2021.100432_b0065","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1016\/j.bcp.2011.03.020","article-title":"Neurotoxicity of methotrexate to hippocampal cells in vivo and in vitro","volume":"82","author":"Yang","year":"2011","journal-title":"Biochem. Pharmacol."},{"issue":"9","key":"10.1016\/j.ebr.2021.100432_b0070","doi-asserted-by":"crossref","first-page":"949","DOI":"10.1200\/JCO.2013.53.0808","article-title":"Methotrexate-induced neurotoxicity and leukoencephalopathy in childhood acute lymphoblastic leukemia","volume":"32","author":"Bhojwani","year":"2014","journal-title":"J. Clin. Oncol."}],"container-title":["Epilepsy & Behavior Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S258998642100006X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S258998642100006X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,12]],"date-time":"2025-11-12T00:08:02Z","timestamp":1762906082000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S258998642100006X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021]]},"references-count":14,"alternative-id":["S258998642100006X"],"URL":"https:\/\/doi.org\/10.1016\/j.ebr.2021.100432","relation":{},"ISSN":["2589-9864"],"issn-type":[{"type":"print","value":"2589-9864"}],"subject":[],"published":{"date-parts":[[2021]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Characterizing the phenotype of drug-resistant childhood epilepsy associated with leukemia: A case series","name":"articletitle","label":"Article Title"},{"value":"Epilepsy & Behavior Reports","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ebr.2021.100432","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"100432"}}