{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T07:13:29Z","timestamp":1792653209867,"version":"4.5.0"},"reference-count":35,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2021,4,1]],"date-time":"2021-04-01T00:00:00Z","timestamp":1617235200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,4,1]],"date-time":"2021-04-01T00:00:00Z","timestamp":1617235200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","award":["1K23HLI13052 2"],"award-info":[{"award-number":["1K23HLI13052 2"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","onlinejase.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of the American Society of Echocardiography"],"published-print":{"date-parts":[[2021,4]]},"DOI":"10.1016\/j.echo.2020.11.008","type":"journal-article","created":{"date-parts":[[2020,11,20]],"date-time":"2020-11-20T16:19:15Z","timestamp":1605889155000},"page":"423-432.e1","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":47,"title":["Early Role of the Atrial-Level Communication in Premature Infants with Patent Ductus Arteriosus"],"prefix":"10.1016","volume":"34","author":[{"given":"Danielle R.","family":"Rios","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fernando de Freitas","family":"Martins","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Afif","family":"El-Khuffash","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dany E.","family":"Weisz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Regan E.","family":"Giesinger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick J.","family":"McNamara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.echo.2020.11.008_bib1","doi-asserted-by":"crossref","first-page":"1020","DOI":"10.1542\/peds.2009-3506","article-title":"Patent ductus arteriosus of the preterm infant","volume":"125","author":"Hamrick","year":"2010","journal-title":"Pediatrics"},{"key":"10.1016\/j.echo.2020.11.008_bib2","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1067\/mpd.2000.106569","article-title":"Ductal shunting, high pulmonary blood flow, and pulmonary hemorrhage","volume":"137","author":"Kluckow","year":"2000","journal-title":"J Pediatr"},{"key":"10.1016\/j.echo.2020.11.008_bib3","doi-asserted-by":"crossref","first-page":"F183","DOI":"10.1136\/fn.75.3.F183","article-title":"Early ductal shunting and intraventricular haemorrhage in ventilated preterm infants","volume":"75","author":"Evans","year":"1996","journal-title":"Arch Dis Child Fetal Neonatal Ed"},{"key":"10.1016\/j.echo.2020.11.008_bib4","doi-asserted-by":"crossref","first-page":"F498","DOI":"10.1136\/adc.2005.092734","article-title":"Patent ductus arteriosus: lack of evidence for common treatments","volume":"92","author":"Bose","year":"2007","journal-title":"Arch Dis Child Fetal Neonatal"},{"key":"10.1016\/j.echo.2020.11.008_bib5","doi-asserted-by":"crossref","first-page":"1488","DOI":"10.1016\/j.jpeds.2015.03.012","article-title":"Association between hemodynamically significant patent ductus arteriosus and bronchopulmonary dysplasia","volume":"166","author":"Schena","year":"2015","journal-title":"J Pediatr"},{"key":"10.1016\/j.echo.2020.11.008_bib6","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1111\/j.1469-8749.1990.tb16957.x","article-title":"Patent ductus arteriosus and cerebral circulation in preterm infants","volume":"32","author":"Shortland","year":"1990","journal-title":"Dev Med Child Neurol"},{"key":"10.1016\/j.echo.2020.11.008_bib7","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1016\/S0022-3476(82)80715-4","article-title":"Abnormal cerebral blood flow patterns in preterm infants with a large patent ductus arteriosus","volume":"101","author":"Martin","year":"1982","journal-title":"J Pediatr"},{"key":"10.1016\/j.echo.2020.11.008_bib8","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1016\/j.jpeds.2013.09.045","article-title":"Changes in cardiac function and cerebral blood flow in relation to peri\/intraventricular hemorrhage in extremely preterm infants","volume":"164","author":"Noori","year":"2014","journal-title":"J Pediatr"},{"key":"10.1016\/j.echo.2020.11.008_bib9","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1038\/s41390-018-0077-x","article-title":"Application of neonatologist performed echocardiography in the assessment of a patent ductus arteriosus","volume":"84","author":"van Laere","year":"2018","journal-title":"Pediatr Res"},{"key":"10.1016\/j.echo.2020.11.008_bib10","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1038\/jp.2008.100","article-title":"Does point-of-care functional echocardiography enhance cardiovascular care in the NICU?","volume":"28","author":"Sehgal","year":"2008","journal-title":"J Perinatol"},{"key":"10.1016\/j.echo.2020.11.008_bib11","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1038\/jp.2013.42","article-title":"Targeted neonatal echocardiography (TnECHO) service in a Canadian neonatal intensive care unit: a 4-year experience","volume":"33","author":"El-Khuffash","year":"2013","journal-title":"J Perinatol"},{"key":"10.1016\/j.echo.2020.11.008_bib12","doi-asserted-by":"crossref","first-page":"1057","DOI":"10.1016\/j.echo.2011.07.014","volume":"24","author":"Mertens","year":"2011","journal-title":"J Am Soc Echocardiogr"},{"key":"10.1016\/j.echo.2020.11.008_bib13","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1016\/j.jpeds.2018.06.045","article-title":"Relationship of patent ductus arteriosus size to echocardiographic markers of shunt volume","volume":"202","author":"de Freitas Martins","year":"2018","journal-title":"J Pediatr"},{"key":"10.1016\/j.echo.2020.11.008_bib14","article-title":"Relationship of patent ductus arteriosus echocardiographic markers with descending aorta diastolic flow","author":"Martins","year":"2020","journal-title":"J Ultrasound Med"},{"key":"10.1016\/j.echo.2020.11.008_bib15","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1016\/S0022-3476(78)80282-0","article-title":"Incidence and evolution of subependymal and intraventricular hemorrhage: a study of infants with birth weights less than 1,500 gm","volume":"92","author":"Papile","year":"1978","journal-title":"J Pediatr"},{"key":"10.1016\/j.echo.2020.11.008_bib16","doi-asserted-by":"crossref","first-page":"1726","DOI":"10.1212\/WNL.58.12.1726","article-title":"Practice parameter: neuroimaging of the neonate","volume":"58","author":"Ment","year":"2002","journal-title":"Neurology"},{"key":"10.1016\/j.echo.2020.11.008_bib17","doi-asserted-by":"crossref","first-page":"1353","DOI":"10.1542\/peds.2005-0249","article-title":"Validation of the National Institutes of Health consensus definition of bronchopulmonary dysplasia","volume":"116","author":"Ehrenkranz","year":"2005","journal-title":"Pediatrics"},{"key":"10.1016\/j.echo.2020.11.008_bib18","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1016\/j.jpeds.2018.04.051","article-title":"Cardiopulmonary adaptation during first day of life in human neonates","volume":"200","author":"Jain","year":"2018","journal-title":"J Pediatr"},{"key":"10.1016\/j.echo.2020.11.008_bib19","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1053\/j.semperi.2011.09.020","article-title":"The ductus arteriosus: a refined approach!","volume":"36","author":"Sehgal","year":"2012","journal-title":"Semin Perinatol"},{"key":"10.1016\/j.echo.2020.11.008_bib20","doi-asserted-by":"crossref","first-page":"F88","DOI":"10.1136\/fn.74.2.F88","article-title":"Early determinants of right and left ventricular output in ventilated preterm infants","volume":"74","author":"Evans","year":"1996","journal-title":"Arch Dis Child Fetal Neonatal Ed"},{"key":"10.1016\/j.echo.2020.11.008_bib21","doi-asserted-by":"crossref","first-page":"786","DOI":"10.1016\/S0022-3476(06)80184-8","article-title":"Incompetence of the foramen ovale in preterm infants supported by mechanical ventilation","volume":"125","author":"Evans","year":"1994","journal-title":"J Pediatr"},{"key":"10.1016\/j.echo.2020.11.008_bib22","doi-asserted-by":"crossref","first-page":"778","DOI":"10.1016\/S0022-3476(06)80183-6","article-title":"Assessment of ductus arteriosus shunt in preterm infants supported by mechanical ventilation: effect of interatrial shunting","volume":"125","author":"Evans","year":"1994","journal-title":"J Pediatr"},{"key":"10.1016\/j.echo.2020.11.008_bib23","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1542\/peds.2006-2329","article-title":"Percutaneous device closure of atrial septal defect in a premature infant with rapid improvement in pulmonary status","volume":"119","author":"Lim","year":"2007","journal-title":"Pediatrics"},{"key":"10.1016\/j.echo.2020.11.008_bib24","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1111\/j.1747-0803.2010.00442.x","article-title":"Transcatheter closure of secundum atrial septal defect in infants less than 12 months of age improves symptoms of chronic lung disease","volume":"7","author":"Thomas","year":"2012","journal-title":"Congenit Heart Dis"},{"key":"10.1016\/j.echo.2020.11.008_bib25","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/j.jpeds.2017.03.021","article-title":"Prophylactic indomethacin compared with delayed conservative management of the patent ductus arteriosus in extremely preterm infants: effects on neonatal outcomes","volume":"187","author":"Liebowitz","year":"2017","journal-title":"J Pediatr"},{"key":"10.1016\/j.echo.2020.11.008_bib26","doi-asserted-by":"crossref","first-page":"945","DOI":"10.1542\/peds.2007-2051","article-title":"Ibuprofen-induced patent ductus arteriosus closure: physiologic, histologic, and biochemical effects on the premature lung","volume":"121","author":"McCurnin","year":"2008","journal-title":"Pediatrics"},{"key":"10.1016\/j.echo.2020.11.008_bib27","doi-asserted-by":"crossref","first-page":"907","DOI":"10.1007\/s00431-009-0983-3","article-title":"Does echocardiography facilitate determination of hemodynamic significance attributable to the ductus arteriosus?","volume":"168","author":"Sehgal","year":"2009","journal-title":"Eur J Pediatr"},{"key":"10.1016\/j.echo.2020.11.008_bib28","doi-asserted-by":"crossref","first-page":"F419","DOI":"10.1136\/adc.2003.027698","article-title":"Severity of the ductal shunt: a comparison of different markers","volume":"90","author":"El Hajjar","year":"2005","journal-title":"Arch Dis Child Fetal Neonatal"},{"key":"10.1016\/j.echo.2020.11.008_bib29","doi-asserted-by":"crossref","first-page":"774","DOI":"10.1016\/S0022-3476(95)70172-9","article-title":"Early echocardiographic prediction of symptomatic patent ductus arteriosus in preterm infants undergoing mechanical ventilation","volume":"127","author":"Kluckow","year":"1995","journal-title":"J Pediatr"},{"key":"10.1016\/j.echo.2020.11.008_bib30","first-page":"1","article-title":"Ductal size indexed to weight and body surface area correlates with morbidities in preterm infants \u226432 weeks","author":"D\u2019Amato","year":"2019","journal-title":"J Matern Fetal Neonatal Med"},{"key":"10.1016\/j.echo.2020.11.008_bib31","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1203\/PDR.0b013e31815b4830","article-title":"Does retrograde diastolic flow in the descending aorta signify impaired systemic perfusion in preterm infants?","volume":"63","author":"Groves","year":"2008","journal-title":"Pediatr Res"},{"key":"10.1016\/j.echo.2020.11.008_bib32","doi-asserted-by":"crossref","first-page":"1135","DOI":"10.1002\/nbm.2927","article-title":"Assessment of PDA shunt and systemic blood flow in newborns using cardiac MRI","volume":"26","author":"Broadhouse","year":"2013","journal-title":"NMR Biomed"},{"key":"10.1016\/j.echo.2020.11.008_bib33","doi-asserted-by":"crossref","first-page":"F15","DOI":"10.1136\/fn.81.1.F15","article-title":"Low cerebral blood flow is a risk factor for severe intraventricular haemorrhage","volume":"81","author":"Meek","year":"1999","journal-title":"Arch Dis Child Fetal Neonatal Ed"},{"key":"10.1016\/j.echo.2020.11.008_bib34","doi-asserted-by":"crossref","first-page":"F188","DOI":"10.1136\/fn.82.3.F188","article-title":"Low superior vena cava flow and intraventricular haemorrhage in preterm infants","volume":"82","author":"Kluckow","year":"2000","journal-title":"Arch Dis Child Fetal Neonatal Ed"},{"key":"10.1016\/j.echo.2020.11.008_bib35","doi-asserted-by":"crossref","first-page":"e20153730","DOI":"10.1542\/peds.2015-3730","article-title":"Patent ductus arteriosus in preterm infants","volume":"137","author":"Benitz","year":"2016","journal-title":"Pediatrics"}],"container-title":["Journal of the American Society of Echocardiography"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0894731720307331?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0894731720307331?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,11]],"date-time":"2026-05-11T13:32:08Z","timestamp":1778506328000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0894731720307331"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,4]]},"references-count":35,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2021,4]]}},"alternative-id":["S0894731720307331"],"URL":"https:\/\/doi.org\/10.1016\/j.echo.2020.11.008","relation":{},"ISSN":["0894-7317"],"issn-type":[{"value":"0894-7317","type":"print"}],"subject":[],"published":{"date-parts":[[2021,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Early Role of the Atrial-Level Communication in Premature Infants with Patent Ductus Arteriosus","name":"articletitle","label":"Article Title"},{"value":"Journal of the American Society of Echocardiography","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.echo.2020.11.008","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"2020 by the American Society of Echocardiography.","name":"copyright","label":"Copyright"}]}}