{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T02:05:01Z","timestamp":1789005901071,"version":"build-2803163510"},"reference-count":28,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2021,6,1]],"date-time":"2021-06-01T00:00:00Z","timestamp":1622505600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,6,1]],"date-time":"2021-06-01T00:00:00Z","timestamp":1622505600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","onlinejase.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of the American Society of Echocardiography"],"published-print":{"date-parts":[[2021,6]]},"DOI":"10.1016\/j.echo.2021.01.004","type":"journal-article","created":{"date-parts":[[2021,1,11]],"date-time":"2021-01-11T19:11:49Z","timestamp":1610392309000},"page":"585-594.e1","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":88,"title":["The Pathophysiological Link between Right Atrial Remodeling and Functional Tricuspid Regurgitation in Patients with Atrial Fibrillation: A Three-Dimensional Echocardiography Study"],"prefix":"10.1016","volume":"34","author":[{"given":"Andrada C.","family":"Guta","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luigi P.","family":"Badano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michele","family":"Tomaselli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diana","family":"Mihalcea","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniela","family":"Bartos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gianfranco","family":"Parati","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Denisa","family":"Muraru","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.echo.2021.01.004_bib1","doi-asserted-by":"crossref","first-page":"213","DOI":"10.2147\/CLEP.S47385","article-title":"Epidemiology of atrial fibrillation: European perspective","volume":"6","author":"Zoni-Berisso","year":"2014","journal-title":"Clin Epidemiol"},{"key":"10.1016\/j.echo.2021.01.004_bib2","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1253\/circj.66.913","article-title":"Impact of atrial fibrillation on tricuspid and mitral annular dilatation and valvular regurgitation","volume":"66","author":"Zhou","year":"2002","journal-title":"Circ J"},{"key":"10.1016\/j.echo.2021.01.004_bib3","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1161\/CIRCIMAGING.116.004897","article-title":"Functional tricuspid regurgitation caused by chronic atrial fibrillation: a real-time 3-dimensional transesophageal echocardiography study","volume":"10","author":"Utsunomiya","year":"2017","journal-title":"Circ Cardiovasc Imaging"},{"key":"10.1016\/j.echo.2021.01.004_bib4","first-page":"315","article-title":"Severe tricuspid regurgitation in the aged: atrial remodeling associated with long-standing atrial fibrillation","volume":"48","author":"Yamasaki","year":"2006","journal-title":"J Cardiol"},{"key":"10.1016\/j.echo.2021.01.004_bib5","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/j.echo.2019.08.016","article-title":"Functional regurgitation of atrioventricular valves and atrial fibrillation: an elusive pathophysiological link deserving further attention","volume":"33","author":"Muraru","year":"2020","journal-title":"J Am Soc Echocardiogr"},{"key":"10.1016\/j.echo.2021.01.004_bib6","doi-asserted-by":"crossref","first-page":"954","DOI":"10.1111\/echo.14327","article-title":"Atrial functional tricuspid regurgitation: an underappreciated cause of secondary tricuspid regurgitation","volume":"36","author":"Silbiger","year":"2019","journal-title":"Echocardiography"},{"key":"10.1016\/j.echo.2021.01.004_bib7","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1093\/ehjci\/jeaa058","article-title":"Understanding tricuspid valve remodelling in atrial fibrillation using three-dimensional echocardiography","volume":"21","author":"Ortiz-Leon","year":"2020","journal-title":"Eur Heart J Cardiovasc Imaging"},{"key":"10.1016\/j.echo.2021.01.004_bib8","first-page":"458","article-title":"Functional tricuspid regurgitation and atrial fibrillation: which comes first, the chicken or the egg?","volume":"5","author":"Muraru","year":"2020","journal-title":"CASE Cardiovasc Imaging Case Rep"},{"key":"10.1016\/j.echo.2021.01.004_bib9","doi-asserted-by":"crossref","first-page":"756","DOI":"10.1093\/ehjci\/jeaa082","article-title":"Does atrial fibrillation affect the tricuspid annulus 3D geometry in patients without severe valve regurgitation?","volume":"21","author":"Muraru","year":"2020","journal-title":"Eur Heart J Cardiovasc Imaging"},{"key":"10.1016\/j.echo.2021.01.004_bib10","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1093\/ehjci\/jet105","article-title":"Recommendations for the echocardiographic assessment of native valvular regurgitation: an executive summary from the European Association of Cardiovascular Imaging","volume":"14","author":"Lancellotti","year":"2013","journal-title":"Eur Heart J Cardiovasc Imaging"},{"key":"10.1016\/j.echo.2021.01.004_bib11","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1016\/j.echo.2017.01.007","article-title":"Recommendations for noninvasive evaluation of native valvular regurgitation: a report from the American Society of Echocardiography developed in collaboration with the Society for Cardiovascular Magnetic Resonance","volume":"30","author":"Zoghbi","year":"2017","journal-title":"J Am Soc Echocardiogr"},{"key":"10.1016\/j.echo.2021.01.004_bib12","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1093\/ehjci\/jeaa282","article-title":"Prognostic validation of partition values for quantitative parameters to grade functional tricuspid regurgitation severity by conventional echocardiography","volume":"22","author":"Muraru","year":"2021","journal-title":"Eur Heart J Cardiovasc Imaging"},{"key":"10.1016\/j.echo.2021.01.004_bib13","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.echo.2014.10.003","article-title":"Recommendations for cardiac chamber quantification by echocardiography in adults: an update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging","volume":"28","author":"Lang","year":"2015","journal-title":"J Am Soc Echocardiogr"},{"key":"10.1016\/j.echo.2021.01.004_bib14","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1016\/j.jcmg.2017.08.022","article-title":"3-Dimensional echocardiographic analysis of the tricuspid annulus provides new insights into tricuspid valve geometry and dynamics","volume":"12","author":"Addetia","year":"2017","journal-title":"JACC Cardiovasc Imaging"},{"key":"10.1016\/j.echo.2021.01.004_bib15","article-title":"Right atrial volume is a major determinant of tricuspid annulus area in functional tricuspid regurgitation: a three-dimensional echocardiographic study","author":"Muraru","year":"2020","journal-title":"Eur Heart J Cardiovasc Imaging"},{"key":"10.1016\/j.echo.2021.01.004_bib16","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1111\/j.1540-8175.2011.01565.x","article-title":"Predictors for the development of severe tricuspid regurgitation with anatomically normal valve in patients with atrial fibrillation","volume":"29","author":"Najib","year":"2012","journal-title":"Echocardiography"},{"key":"10.1016\/j.echo.2021.01.004_bib17","doi-asserted-by":"crossref","first-page":"1371","DOI":"10.1016\/j.amjcard.2017.01.037","article-title":"Frequency and associated clinical features of functional tricuspid regurgitation in patients with chronic atrial fibrillation","volume":"119","author":"Zhao","year":"2017","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.echo.2021.01.004_bib18","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1016\/j.jcmg.2018.10.035","article-title":"3-Dimensional echocardiography in imaging the tricuspid valve","volume":"12","author":"Muraru","year":"2019","journal-title":"JACC Cardiovasc Imaging"},{"key":"10.1016\/j.echo.2021.01.004_bib19","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/j.ijcard.2016.11.075","article-title":"The right atrium and tricuspid annulus are cardinal structures in tricuspid regurgitation with or without pulmonary hypertension","volume":"230","author":"Nemoto","year":"2017","journal-title":"Int J Cardiol"},{"key":"10.1016\/j.echo.2021.01.004_bib20","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1016\/j.jtcvs.2015.05.009","article-title":"Pathogenic structural heart changes in early tricuspid regurgitation","volume":"150","author":"Nemoto","year":"2015","journal-title":"J Thorac Cardiovasc Surg"},{"key":"10.1016\/j.echo.2021.01.004_bib21","doi-asserted-by":"crossref","first-page":"920","DOI":"10.1161\/CIRCULATIONAHA.110.003897","article-title":"In\u00a0vitro characterization of the mechanisms responsible for functional tricuspid regurgitation","volume":"124","author":"Spinner","year":"2011","journal-title":"Circulation"},{"key":"10.1016\/j.echo.2021.01.004_bib22","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1161\/CIRCULATIONAHA.106.611889","article-title":"Geometric determinants of functional tricuspid regurgitation: insights from 3-dimensional echocardiography","volume":"114","author":"Ton-Nu","year":"2006","journal-title":"Circulation"},{"key":"10.1016\/j.echo.2021.01.004_bib23","doi-asserted-by":"crossref","first-page":"996","DOI":"10.1007\/s10439-011-0471-6","article-title":"The effects of a three-dimensional, saddle-shaped annulus on anterior and posterior leaflet stretch and regurgitation of the tricuspid valve","volume":"40","author":"Spinner","year":"2012","journal-title":"Ann Biomed Eng"},{"key":"10.1016\/j.echo.2021.01.004_bib24","doi-asserted-by":"crossref","first-page":"2739","DOI":"10.1093\/eurheartj\/ehx391","article-title":"2017 ESC\/EACTS guidelines for the management of valvular heart disease","volume":"38","author":"Baumgartner","year":"2017","journal-title":"Eur Heart J"},{"key":"10.1016\/j.echo.2021.01.004_bib25","first-page":"e57","article-title":"2014 AHA\/ACC guideline for the management of patients with valvular heart disease: executive summary: a report of the American College of Cardiology\/American Heart Association task force on practice guidelines","volume":"63","author":"Nishimura","year":"2014","journal-title":"Circulation"},{"key":"10.1016\/j.echo.2021.01.004_bib26","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCIMAGING.114.002714","article-title":"Leaflet area as a determinant of tricuspid regurgitation severity in patients with pulmonary hypertension","volume":"8","author":"Afilalo","year":"2015","journal-title":"Circ Cardiovasc Imaging"},{"key":"10.1016\/j.echo.2021.01.004_bib27","doi-asserted-by":"crossref","first-page":"1068","DOI":"10.1093\/ehjci\/jeaa194","article-title":"Tricuspid valve geometry and right heart remodelling: insights into the mechanism of atrial functional tricuspid regurgitation","volume":"21","author":"Utsunomiya","year":"2020","journal-title":"Eur Heart J Cardiovasc Imaging"},{"key":"10.1016\/j.echo.2021.01.004_bib28","doi-asserted-by":"crossref","first-page":"842","DOI":"10.1007\/s00380-019-01546-3","article-title":"Successful catheter ablation of persistent atrial fibrillation is associated with improvement in functional tricuspid regurgitation and right heart reverse remodeling","volume":"35","author":"Itakura","year":"2020","journal-title":"Heart Vessels"}],"container-title":["Journal of the American Society of Echocardiography"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0894731721000067?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0894731721000067?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T05:07:50Z","timestamp":1760245670000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0894731721000067"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,6]]},"references-count":28,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2021,6]]}},"alternative-id":["S0894731721000067"],"URL":"https:\/\/doi.org\/10.1016\/j.echo.2021.01.004","relation":{},"ISSN":["0894-7317"],"issn-type":[{"value":"0894-7317","type":"print"}],"subject":[],"published":{"date-parts":[[2021,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The Pathophysiological Link between Right Atrial Remodeling and Functional Tricuspid Regurgitation in Patients with Atrial Fibrillation: A Three-Dimensional Echocardiography Study","name":"articletitle","label":"Article Title"},{"value":"Journal of the American Society of Echocardiography","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.echo.2021.01.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"2021 Published by Elsevier Inc. on behalf of the American Society of Echocardiography.","name":"copyright","label":"Copyright"}]}}