{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,8]],"date-time":"2026-02-08T08:20:03Z","timestamp":1770538803877,"version":"3.49.0"},"reference-count":30,"publisher":"Elsevier BV","issue":"7","license":[{"start":{"date-parts":[[2022,7,1]],"date-time":"2022-07-01T00:00:00Z","timestamp":1656633600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,7,1]],"date-time":"2022-07-01T00:00:00Z","timestamp":1656633600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","onlinejase.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of the American Society of Echocardiography"],"published-print":{"date-parts":[[2022,7]]},"DOI":"10.1016\/j.echo.2022.02.003","type":"journal-article","created":{"date-parts":[[2022,2,11]],"date-time":"2022-02-11T11:28:54Z","timestamp":1644578934000},"page":"715-726","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":10,"title":["Echocardiographic Biventricular Coupling Index to Predict Precapillary Pulmonary Hypertension"],"prefix":"10.1016","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1407-6087","authenticated-orcid":false,"given":"Stefano","family":"Albani","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4538-6811","authenticated-orcid":false,"given":"Davide","family":"Stolfo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ashwin","family":"Venkateshvaran","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vlad","family":"Chubuchny","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Federico","family":"Biondi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonio","family":"De Luca","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesco","family":"Lo Giudice","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emilio M.","family":"Pasanisi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christina","family":"Petersen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edoardo","family":"Air\u00f2","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carolina","family":"Bauleo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marco","family":"Ciardetti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michele","family":"Coceani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bruno","family":"Formichi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jens","family":"Spiesshoefer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gianluigi","family":"Savarese","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lars H.","family":"Lund","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michele","family":"Emdin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gianfranco","family":"Sinagra","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aristomenis","family":"Manouras","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alberto","family":"Giannoni","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.echo.2022.02.003_bib1","first-page":"363","article-title":"World Health Organization group I pulmonary hypertension: epidemiology and pathophysiology","volume":"34","author":"Prins","year":"2016","journal-title":"Cardiol Clin"},{"key":"10.1016\/j.echo.2022.02.003_bib2","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1161\/CIRCHEARTFAILURE.108.805374","article-title":"The effects of vasodilators in pulmonary hypertension pulmonary vascular or peripheral vascular?","volume":"2","author":"Rich","year":"2009","journal-title":"Circ Heart Fail"},{"key":"10.1016\/j.echo.2022.02.003_bib3","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/j.ijcard.2018.09.043","article-title":"Pulmonary vasodilator therapies are of no benefit in pulmonary hypertension due to left heart disease: a meta-analysis","volume":"273","author":"Cao","year":"2018","journal-title":"Int J Cardiol"},{"key":"10.1016\/j.echo.2022.02.003_bib4","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1093\/eurheartj\/ehv317","article-title":"2015 ESC\/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension","volume":"37","author":"Gali\u00e8","year":"2016","journal-title":"Eur Heart J"},{"key":"10.1016\/j.echo.2022.02.003_bib5","doi-asserted-by":"crossref","first-page":"891","DOI":"10.1002\/jum.14424","article-title":"Distinction between precapillary and postcapillary pulmonary hypertension by the atrial volume ratio on transthoracic echocardiography","volume":"37","author":"Saito","year":"2018","journal-title":"J Ultrasound Med"},{"key":"10.1016\/j.echo.2022.02.003_bib6","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1016\/j.echo.2014.09.004","article-title":"Echocardiographic prediction of pre versus postcapillary pulmonary hypertension","volume":"28","author":"D\u2019Alto","year":"2015","journal-title":"J Am Soc Echocardiogr"},{"issue":"suppl 60","key":"10.1016\/j.echo.2022.02.003_bib7","first-page":"PA1873","article-title":"Echocardiography for the diagnosis of pulmonary vascular disease","volume":"48","author":"D\u2019Alto","year":"2016","journal-title":"Eur Respir J"},{"key":"10.1016\/j.echo.2022.02.003_bib8","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1161\/CIRCIMAGING.112.976654","article-title":"A simple echocardiographic prediction rule for hemodynamics in pulmonary hypertension","volume":"5","author":"Opotowsky","year":"2012","journal-title":"Circ Cardiovasc Imaging"},{"issue":"suppl 1","key":"10.1016\/j.echo.2022.02.003_bib9","first-page":"P3524","article-title":"Atrial workload distribution\u2014a novel echocardiographic parameter for the differentiation of pre-capillary from post-capillary pulmonary hypertension","volume":"38","author":"Vijiiac","year":"2017","journal-title":"Eur Heart J"},{"key":"10.1016\/j.echo.2022.02.003_bib10","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1016\/j.ijcard.2016.03.035","article-title":"ePLAR\u2014the echocardiographic pulmonary to left atrial ratio\u2014a novel non-invasive parameter to differentiate pre-capillary and post-capillary pulmonary hypertension","volume":"212","author":"Scalia","year":"2016","journal-title":"Int J Cardiol"},{"key":"10.1016\/j.echo.2022.02.003_bib11","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1046\/j.1365-2281.2001.00300.x","article-title":"Influence of right ventricular pre- and afterload on right ventricular ejection fraction and preload recruitable stroke work relation","volume":"21","author":"Burger","year":"2001","journal-title":"Clin Physiol"},{"key":"10.1016\/j.echo.2022.02.003_bib12","doi-asserted-by":"crossref","first-page":"1350","DOI":"10.1016\/j.echo.2015.07.017","article-title":"Echocardiographic estimation of right ventricular stroke work in children with pulmonary arterial hypertension: comparison with invasive measurements","volume":"28","author":"Di Maria","year":"2015","journal-title":"J Am Soc Echocardiogr"},{"key":"10.1016\/j.echo.2022.02.003_bib13","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1016\/j.jacc.2016.10.047","article-title":"The relationship between the right ventricle and its load in pulmonary hypertension","volume":"69","author":"Vonk Noordegraaf","year":"2017","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.echo.2022.02.003_bib14","doi-asserted-by":"crossref","first-page":"1463","DOI":"10.1016\/j.jacc.2018.12.076","article-title":"Anatomy, function, and dysfunction of the right ventricle: JACC state-of-the-art review","volume":"73","author":"Sanz","year":"2019","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.echo.2022.02.003_bib15","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1016\/j.echo.2019.09.013","article-title":"Parameters of right ventricular function reveal ventricular-vascular mismatch as determined by right ventricular stroke work versus pulmonary vascular resistance in children with pulmonary hypertension","volume":"33","author":"Di Maria","year":"2020","journal-title":"J Am Soc Echocardiogr"},{"key":"10.1016\/j.echo.2022.02.003_bib16","doi-asserted-by":"crossref","first-page":"886","DOI":"10.1016\/j.cardfail.2012.10.018","article-title":"Echocardiographic evaluation of right ventricular stroke work index in advanced heart failure: a new index?","volume":"18","author":"Frea","year":"2012","journal-title":"J Card Fail"},{"key":"10.1016\/j.echo.2022.02.003_bib17","doi-asserted-by":"crossref","first-page":"1937","DOI":"10.1016\/j.jacc.2017.01.058","article-title":"Estimating left ventricular filling pressure by echocardiography","volume":"69","author":"Andersen","year":"2017","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.echo.2022.02.003_bib18","doi-asserted-by":"crossref","first-page":"682","DOI":"10.2459\/JCM.0000000000000841","article-title":"Reliability of noninvasive hemodynamic assessment with Doppler echocardiography: comparison with the invasive evaluation","volume":"20","author":"de Scordilli","year":"2019","journal-title":"J Cardiovasc Med (Hagerstown)"},{"key":"10.1016\/j.echo.2022.02.003_bib19","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/j.ijcard.2019.05.025","article-title":"The additive value of echocardiographic pulmonary to left atrial global strain ratio in the diagnosis of pulmonary hypertension","volume":"292","author":"Venkateshvaran","year":"2019","journal-title":"Int J Cardiol"},{"key":"10.1016\/j.echo.2022.02.003_bib20","doi-asserted-by":"crossref","first-page":"1216","DOI":"10.1002\/ehf2.13183","article-title":"A novel echocardiographic method for estimation of pulmonary artery wedge pressure and pulmonary vascular resistance","volume":"8","author":"Chubuchny","year":"2021","journal-title":"ESC Heart Fail"},{"key":"10.1016\/j.echo.2022.02.003_bib21","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.echo.2014.10.003","article-title":"Recommendations for cardiac chamber quantification by echocardiography in adults: an update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging","volume":"28","author":"Lang","year":"2015","journal-title":"J Am Soc Echocardiogr"},{"key":"10.1016\/j.echo.2022.02.003_bib22","doi-asserted-by":"crossref","first-page":"1321","DOI":"10.1093\/ehjci\/jew082","article-title":"Recommendations for the evaluation of left ventricular diastolic function by echocardiography: an update from the American society of echocardiography and the European association of cardiovascular imaging","volume":"17","author":"Nagueh","year":"2016","journal-title":"Eur Heart J Cardiovasc Imaging"},{"key":"10.1016\/j.echo.2022.02.003_bib23","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/j.echo.2010.01.003","article-title":"Echocardiographic indexes for the non-invasive evaluation of pulmonary hemodynamics","volume":"23","author":"Milan","year":"2010","journal-title":"J Am Soc Echocardiogr"},{"key":"10.1016\/j.echo.2022.02.003_bib24","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1161\/CIRCHEARTFAILURE.108.809590","article-title":"Doppler echocardiography in advanced systolic heart failure: a noninvasive alternative to Swan-Ganz catheter","volume":"3","author":"Temporelli","year":"2010","journal-title":"Circ Hear Fail"},{"key":"10.1016\/j.echo.2022.02.003_bib25","doi-asserted-by":"crossref","first-page":"e004536","DOI":"10.1161\/CIRCOUTCOMES.118.004536","article-title":"The growing burden of pulmonary hypertension in the modern era: a zebra no more?","volume":"11","author":"Mathai","year":"2018","journal-title":"Circ Cardiovasc Qual Outcomes"},{"key":"10.1016\/j.echo.2022.02.003_bib26","doi-asserted-by":"crossref","first-page":"D100","DOI":"10.1016\/j.jacc.2013.10.033","article-title":"Pulmonary hypertension due to left heart diseases","volume":"62","author":"Vachi\u00e9ry","year":"2013","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.echo.2022.02.003_bib27","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1183\/16000617.0062-2015","article-title":"Right heart catheterisation: best practice and pitfalls in pulmonary hypertension","volume":"24","author":"Rosenkranz","year":"2015","journal-title":"Eur Respir Rev"},{"key":"10.1016\/j.echo.2022.02.003_bib28","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1016\/j.jacc.2016.05.047","article-title":"Pre-capillary, combined, and post-capillary pulmonary hypertension: a pathophysiological continuum","volume":"68","author":"Opitz","year":"2016","journal-title":"J Am Coll Cardiol"},{"issue":"25 suppl","key":"10.1016\/j.echo.2022.02.003_bib29","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/j.jacc.2013.10.027","article-title":"Right heart adaptation to pulmonary arterial hypertension: physiology and pathobiology","volume":"62","author":"Vonk-Noordegraaf","year":"2013","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.echo.2022.02.003_bib30","doi-asserted-by":"crossref","first-page":"1034","DOI":"10.1016\/j.jcmg.2016.01.027","article-title":"The prognostic impact of the evolution of RV function in idiopathic DCM","volume":"9","author":"Merlo","year":"2016","journal-title":"JACC Cardiovasc Imaging"}],"container-title":["Journal of the American Society of Echocardiography"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S089473172200061X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S089473172200061X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T05:09:22Z","timestamp":1760245762000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S089473172200061X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,7]]},"references-count":30,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2022,7]]}},"alternative-id":["S089473172200061X"],"URL":"https:\/\/doi.org\/10.1016\/j.echo.2022.02.003","relation":{},"ISSN":["0894-7317"],"issn-type":[{"value":"0894-7317","type":"print"}],"subject":[],"published":{"date-parts":[[2022,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Echocardiographic Biventricular Coupling Index to Predict Precapillary Pulmonary Hypertension","name":"articletitle","label":"Article Title"},{"value":"Journal of the American Society of Echocardiography","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.echo.2022.02.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"2022 by the American Society of Echocardiography.","name":"copyright","label":"Copyright"}]}}