{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T16:50:23Z","timestamp":1780419023962,"version":"3.54.1"},"reference-count":19,"publisher":"Elsevier BV","issue":"9","license":[{"start":{"date-parts":[[2022,9,1]],"date-time":"2022-09-01T00:00:00Z","timestamp":1661990400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,9,1]],"date-time":"2022-09-01T00:00:00Z","timestamp":1661990400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","onlinejase.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of the American Society of Echocardiography"],"published-print":{"date-parts":[[2022,9]]},"DOI":"10.1016\/j.echo.2022.04.006","type":"journal-article","created":{"date-parts":[[2022,4,23]],"date-time":"2022-04-23T17:28:06Z","timestamp":1650734886000},"page":"933-939","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"title":["Color Doppler Splay in Mitral Regurgitation: Hemodynamic Correlates and Outcomes in a Clinical Cohort"],"prefix":"10.1016","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7253-1837","authenticated-orcid":false,"given":"Jonas","family":"Verbeke","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Victor","family":"Kamoen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simon","family":"Calle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marc","family":"De Buyzere","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank","family":"Timmermans","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.echo.2022.04.006_bib1","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1016\/j.echo.2017.01.007","article-title":"Recommendations for noninvasive evaluation of native valvular regurgitation: a report from the American Society of Echocardiography developed in collaboration with the Society for Cardiovascular Magnetic Resonance","volume":"30","author":"Zoghbi","year":"2017","journal-title":"J Am Soc Echocardiogr"},{"key":"10.1016\/j.echo.2022.04.006_bib2","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1056\/NEJMoa041451","article-title":"Quantitative determinants of the outcome of asymptomatic mitral regurgitation","volume":"352","author":"Enriquez-Sarano","year":"2005","journal-title":"N Engl J Med"},{"key":"10.1016\/j.echo.2022.04.006_bib3","first-page":"2421","article-title":"2017 ACC expert consensus decision pathway on the management of mitral regurgitation: a report of the American College of Cardiology Task Force on Expert Consensus Decision Pathways","volume":"70","author":"O\u2019Gara","year":"2017","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.echo.2022.04.006_bib4","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1093\/eurheartj\/ehab395","article-title":"2021 ESC\/EACTS guidelines for the management of valvular heart disease","volume":"43","author":"Vahanian","year":"2022","journal-title":"Eur Heart J"},{"key":"10.1016\/j.echo.2022.04.006_bib5","doi-asserted-by":"crossref","first-page":"1212","DOI":"10.1016\/j.echo.2020.05.002","article-title":"Color Doppler splay: a clue to the presence of significant mitral regurgitation","volume":"33","author":"Wiener","year":"2020","journal-title":"J Am Soc Echocardiogr"},{"key":"10.1016\/j.echo.2022.04.006_bib6","doi-asserted-by":"crossref","first-page":"1220","DOI":"10.1016\/j.echo.2020.08.003","article-title":"The artifact that tells the truth: color Doppler splay unmasking significant mitral regurgitation","volume":"33","author":"Bertrand","year":"2020","journal-title":"J Am Soc Echocardiogr"},{"key":"10.1016\/j.echo.2022.04.006_bib7","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/j.echo.2019.07.021","article-title":"The average pixel intensity method and outcome of mitral regurgitation in mitral valve prolapse","volume":"33","author":"Kamoen","year":"2020","journal-title":"J Am Soc Echocardiogr"},{"key":"10.1016\/j.echo.2022.04.006_bib8","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/j.amjcard.2020.12.027","article-title":"Diagnostic and prognostic value of several color Doppler jet grading methods in patients with mitral regurgitation","volume":"143","author":"Kamoen","year":"2021","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.echo.2022.04.006_bib9","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1016\/j.echo.2016.01.009","article-title":"Fact or artifact in two-dimensional echocardiography: avoiding misdiagnosis and missed diagnosis","volume":"29","author":"Bertrand","year":"2016","journal-title":"J Am Soc Echocardiogr"},{"key":"10.1016\/j.echo.2022.04.006_bib10","doi-asserted-by":"crossref","first-page":"1770","DOI":"10.1016\/j.ultrasmedbio.2018.04.002","article-title":"Adaptive color gain for vena contracta quantification in valvular regurgitation","volume":"44","author":"Kozlowski","year":"2018","journal-title":"Ultrasound Med Biol"},{"key":"10.1016\/j.echo.2022.04.006_bib11","doi-asserted-by":"crossref","first-page":"1329","DOI":"10.1111\/echo.14695","article-title":"Outcome of degenerative nonprolapse mitral regurgitation using the average pixel intensity method","volume":"37","author":"Kamoen","year":"2020","journal-title":"Echocardiography"},{"key":"10.1016\/j.echo.2022.04.006_bib12","doi-asserted-by":"crossref","first-page":"2303","DOI":"10.1016\/j.jcmg.2021.05.017","article-title":"Functional mitral regurgitation outcome and grading in heart failure with reduced ejection fraction","volume":"14","author":"Benfari","year":"2021","journal-title":"JACC Cardiovasc Imaging"},{"key":"10.1016\/j.echo.2022.04.006_bib13","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1161\/01.CIR.81.1.247","article-title":"Quantification of jet flow by momentum analysis: an in\u00a0vitro color Doppler flow study","volume":"81","author":"Thomas","year":"1990","journal-title":"Circulation"},{"key":"10.1016\/j.echo.2022.04.006_bib14","doi-asserted-by":"crossref","first-page":"1022","DOI":"10.1016\/j.echo.2021.05.014","article-title":"Response to: \u201cColor Doppler splay: a new tool for the assessment of valvular regurgitations?\u201d by Allievi, et\u00a0al","volume":"34","author":"Wiener","year":"2021","journal-title":"J Am Soc Echocardiogr"},{"key":"10.1016\/j.echo.2022.04.006_bib15","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1016\/0735-1097(94)00434-R","article-title":"Effective mitral regurgitant orifice area: clinical use and pitfalls of the proximal isovelocity surface area method","volume":"25","author":"Enriquez-Sarano","year":"1995","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.echo.2022.04.006_bib16","doi-asserted-by":"crossref","first-page":"1015","DOI":"10.1152\/ajpheart.00275.2011","article-title":"A three-dimensional insight into the complexity of flow convergence in mitral regurgitation: adjunctive benefit of anatomic regurgitant orifice area","volume":"301","author":"Chandra","year":"2011","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"10.1016\/j.echo.2022.04.006_bib17","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1161\/CIRCIMAGING.113.001457","article-title":"Differential effect of 3-dimensional color Doppler echocardiography for the quantification of mitral regurgitation according to the severity and characteristics","volume":"7","author":"Choi","year":"2014","journal-title":"Circ Cardiovasc Imaging"},{"key":"10.1016\/j.echo.2022.04.006_bib18","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1016\/j.ijcard.2011.12.015","article-title":"Avoiding bias in measuring \u201chemisphere radius\u201d in echocardiographic mitral regurgitation quantification: Mona Lisa PISA","volume":"155","author":"Moraldo","year":"2012","journal-title":"Int J Cardiol"},{"key":"10.1016\/j.echo.2022.04.006_bib19","doi-asserted-by":"crossref","first-page":"1021","DOI":"10.1016\/j.echo.2021.05.003","article-title":"Color Doppler splay: a new tool for the assessment of valvular regurgitations?","volume":"34","author":"Allievi","year":"2021","journal-title":"J Am Soc Echocardiogr"}],"container-title":["Journal of the American Society of Echocardiography"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0894731722002231?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0894731722002231?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T05:09:40Z","timestamp":1760245780000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0894731722002231"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,9]]},"references-count":19,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2022,9]]}},"alternative-id":["S0894731722002231"],"URL":"https:\/\/doi.org\/10.1016\/j.echo.2022.04.006","relation":{},"ISSN":["0894-7317"],"issn-type":[{"value":"0894-7317","type":"print"}],"subject":[],"published":{"date-parts":[[2022,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Color Doppler Splay in Mitral Regurgitation: Hemodynamic Correlates and Outcomes in a Clinical Cohort","name":"articletitle","label":"Article Title"},{"value":"Journal of the American Society of Echocardiography","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.echo.2022.04.006","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"2022 by the American Society of Echocardiography.","name":"copyright","label":"Copyright"}]}}