{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T19:59:06Z","timestamp":1791489546091,"version":"4.3.4"},"reference-count":82,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,3,18]],"date-time":"2024-03-18T00:00:00Z","timestamp":1710720000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100006397","name":"National Taiwan Normal University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100006397","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100020595","name":"National Science and Technology Council","doi-asserted-by":"publisher","award":["112-2320-B-003 -005"],"award-info":[{"award-number":["112-2320-B-003 -005"]}],"id":[{"id":"10.13039\/100020595","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["thelancet.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["eClinicalMedicine"],"published-print":{"date-parts":[[2024,5]]},"DOI":"10.1016\/j.eclinm.2024.102578","type":"journal-article","created":{"date-parts":[[2024,4,8]],"date-time":"2024-04-08T17:54:26Z","timestamp":1712598866000},"page":"102578","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":25,"special_numbering":"C","title":["Prevalence and determinants of constipation in children in Asia: a systematic review and meta-analysis"],"prefix":"10.1016","volume":"71","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-4506-4921","authenticated-orcid":false,"given":"Felicia","family":"Djurijanto","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3723-560X","authenticated-orcid":false,"given":"Shyh-Hsiang","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1051-5107","authenticated-orcid":false,"given":"Nguyen-Phong","family":"Vo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nguyen Quoc Khanh","family":"Le","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9434-2997","authenticated-orcid":false,"given":"Anh","family":"Nguyen-Hoang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Szu-Chuan","family":"Shen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chung-Hsin","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jian-Yu","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5655-7292","authenticated-orcid":false,"given":"Ngan Thi Kim","family":"Nguyen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"10263","key":"10.1016\/j.eclinm.2024.102578_bib1","doi-asserted-by":"crossref","first-page":"1664","DOI":"10.1016\/S0140-6736(20)32115-2","article-title":"Functional gastrointestinal disorders: advances in understanding and management","volume":"396","author":"Black","year":"2020","journal-title":"Lancet"},{"issue":"1","key":"10.1016\/j.eclinm.2024.102578_bib2","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1097\/MPG.0b013e3181e67058","article-title":"Direct medical costs of constipation from childhood to early adulthood: a population-based birth cohort study","volume":"52","author":"Choung","year":"2011","journal-title":"J\u00a0Pediatr Gastroenterol Nutr"},{"issue":"5","key":"10.1016\/j.eclinm.2024.102578_bib3","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1007\/s40272-015-0142-4","article-title":"Management of functional constipation in children: therapy in practice","volume":"17","author":"Koppen","year":"2015","journal-title":"Paediatr Drugs"},{"issue":"1","key":"10.1016\/j.eclinm.2024.102578_bib4","doi-asserted-by":"crossref","first-page":"1","DOI":"10.5223\/pghn.2017.20.1.1","article-title":"The new Rome IV criteria for functional gastrointestinal disorders in infants and toddlers","volume":"20","author":"Zeevenhooven","year":"2017","journal-title":"Pediatr Gastroenterol Hepatol Nutr"},{"issue":"2","key":"10.1016\/j.eclinm.2024.102578_bib5","doi-asserted-by":"crossref","first-page":"e309","DOI":"10.1542\/peds.2008-3055","article-title":"Prevalence and associated clinical characteristics of behavior problems in constipated children","volume":"125","author":"van Dijk","year":"2010","journal-title":"Pediatrics"},{"issue":"1S","key":"10.1016\/j.eclinm.2024.102578_bib6","first-page":"S51","article-title":"Iatrogenic constipation in gastrointestinal surgery","volume":"159","author":"Diebakate-Scordamaglia","year":"2022","journal-title":"J\u00a0Visc Surg"},{"issue":"1","key":"10.1016\/j.eclinm.2024.102578_bib7","doi-asserted-by":"crossref","first-page":"e156","DOI":"10.1542\/peds.2009-1009","article-title":"Long-term prognosis for childhood constipation: clinical outcomes in adulthood","volume":"126","author":"Bongers","year":"2010","journal-title":"Pediatrics"},{"issue":"7","key":"10.1016\/j.eclinm.2024.102578_bib8","doi-asserted-by":"crossref","first-page":"2297","DOI":"10.1007\/s00431-021-04013-2","article-title":"Functional gastrointestinal disorders in children: agreement between Rome III and Rome IV diagnoses","volume":"180","author":"Baaleman","year":"2021","journal-title":"Eur J Pediatr"},{"issue":"5","key":"10.1016\/j.eclinm.2024.102578_bib9","doi-asserted-by":"crossref","first-page":"1527","DOI":"10.1053\/j.gastro.2005.08.063","article-title":"Childhood functional gastrointestinal disorders: child\/adolescent","volume":"130","author":"Rasquin","year":"2006","journal-title":"Gastroenterology"},{"issue":"2","key":"10.1016\/j.eclinm.2024.102578_bib10","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1590\/s0004-2803.202202000-53","article-title":"A\u00a0systematic review and meta-analysis in schoolchildren and adolescents with functional gastrointestinal disorders according to Rome IV criteria","volume":"59","author":"Velasco-Benitez","year":"2022","journal-title":"Arq Gastroenterol"},{"issue":"5","key":"10.1016\/j.eclinm.2024.102578_bib11","doi-asserted-by":"crossref","first-page":"376","DOI":"10.5223\/pghn.2022.25.5.376","article-title":"Functional gastrointestinal disorders in neonates and toddlers according to the Rome IV criteria: a systematic review and meta-analysis","volume":"25","author":"Velasco-Benitez","year":"2022","journal-title":"Pediatr Gastroenterol Hepatol Nutr"},{"issue":"8","key":"10.1016\/j.eclinm.2024.102578_bib12","doi-asserted-by":"crossref","first-page":"638","DOI":"10.1016\/S2468-1253(21)00111-4","article-title":"Global prevalence of functional constipation according to the Rome criteria: a systematic review and meta-analysis","volume":"6","author":"Barberio","year":"2021","journal-title":"Lancet Gastroenterol Hepatol"},{"issue":"5","key":"10.1016\/j.eclinm.2024.102578_bib13","doi-asserted-by":"crossref","first-page":"872","DOI":"10.1542\/peds.2013-3995","article-title":"Gastrointestinal symptoms in autism spectrum disorder: a meta-analysis","volume":"133","author":"McElhanon","year":"2014","journal-title":"Pediatrics"},{"issue":"9","key":"10.1016\/j.eclinm.2024.102578_bib14","doi-asserted-by":"crossref","first-page":"934","DOI":"10.1016\/j.jclinepi.2011.11.014","article-title":"Assessing risk of bias in prevalence studies: modification of an existing tool and evidence of interrater agreement","volume":"65","author":"Hoy","year":"2012","journal-title":"J\u00a0Clin Epidemiol"},{"key":"10.1016\/j.eclinm.2024.102578_bib15","first-page":"76","article-title":"WHO child growth standards based on length\/height, weight and age","volume":"450","author":"Group WMGRS","year":"2006","journal-title":"Acta Paediatr Suppl"},{"issue":"6","key":"10.1016\/j.eclinm.2024.102578_bib16","first-page":"431","article-title":"A\u00a0community-based study of the prevalence of constipation in young children and the role of dietary fibre","volume":"11","author":"Ip","year":"2005","journal-title":"Hong Kong Med J"},{"issue":"4","key":"10.1016\/j.eclinm.2024.102578_bib17","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1111\/j.1440-1754.2007.01212.x","article-title":"Increased prevalence of constipation in pre-school children is attributable to under-consumption of plant foods: a community-based study","volume":"44","author":"Lee","year":"2008","journal-title":"J\u00a0Paediatr Child Health"},{"issue":"10","key":"10.1016\/j.eclinm.2024.102578_bib18","doi-asserted-by":"crossref","first-page":"1217","DOI":"10.1111\/j.1651-2227.1996.tb18232.x","article-title":"Enuresis: prevalence and associated factors among primary school children in Saudi Arabia","volume":"85","author":"Kalo","year":"1996","journal-title":"Acta Paediatr"},{"issue":"5","key":"10.1016\/j.eclinm.2024.102578_bib19","first-page":"315","article-title":"Frequency of enuresis, constipation and enuresis association with constipation in a group of school children aged 5-9 years in malatya, Turkey","volume":"33","author":"U\u011furalp","year":"2003","journal-title":"Turk J Med Sci"},{"issue":"1","key":"10.1016\/j.eclinm.2024.102578_bib20","first-page":"403","article-title":"The micturition habits and prevalence of daytime urinary incontinence in Japanese primary school children","volume":"171","author":"Kajiwara","year":"2004","journal-title":"J\u00a0Urol"},{"issue":"10","key":"10.1016\/j.eclinm.2024.102578_bib21","doi-asserted-by":"crossref","first-page":"700","DOI":"10.1111\/j.1440-1754.2007.01165.x","article-title":"Factors associated with childhood constipation","volume":"43","author":"Inan","year":"2007","journal-title":"J\u00a0Paediatr Child Health"},{"issue":"10","key":"10.1016\/j.eclinm.2024.102578_bib22","first-page":"657","article-title":"[An epidemiologic study of functional bowel disorders in adolescents in China]","volume":"87","author":"Zhou","year":"2007","journal-title":"Zhonghua Yixue Zazhi"},{"issue":"3","key":"10.1016\/j.eclinm.2024.102578_bib23","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1093\/tropej\/fmm114","article-title":"Recurrent abdominal pain syndrome in a cohort of Sri Lankan children and adolescents","volume":"54","author":"Devanarayana","year":"2008","journal-title":"J\u00a0Trop Pediatr"},{"issue":"12","key":"10.1016\/j.eclinm.2024.102578_bib24","first-page":"917","article-title":"[Epidemiology of mild gastrointestinal disorders among infants and young children in Shanghai area]","volume":"47","author":"Liu","year":"2009","journal-title":"Zhonghua Er Ke Za Zhi"},{"issue":"23-24","key":"10.1016\/j.eclinm.2024.102578_bib25","doi-asserted-by":"crossref","first-page":"3390","DOI":"10.1111\/j.1365-2702.2010.03362.x","article-title":"Investigating factors associated with functional constipation of primary school children in Hong Kong","volume":"19","author":"Chan","year":"2010","journal-title":"J\u00a0Clin Nurs"},{"issue":"1","key":"10.1016\/j.eclinm.2024.102578_bib26","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/j.urology.2009.12.022","article-title":"An epidemiologic study of voiding and bowel habits in Korean children: a nationwide multicenter study","volume":"76","author":"Chung","year":"2010","journal-title":"Urology"},{"issue":"3","key":"10.1016\/j.eclinm.2024.102578_bib27","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1093\/tropej\/fmp077","article-title":"Association between constipation and stressful life events in a cohort of Sri Lankan children and adolescents","volume":"56","author":"Devanarayana","year":"2010","journal-title":"J\u00a0Trop Pediatr"},{"issue":"7","key":"10.1016\/j.eclinm.2024.102578_bib28","first-page":"751","article-title":"[Epidemiologic survey on the prevalence and distribution of childhood functional constipation in the northern areas of China: a population-based study]","volume":"31","author":"Zhang","year":"2010","journal-title":"Zhonghua Liuxingbingxue Zazhi"},{"issue":"6","key":"10.1016\/j.eclinm.2024.102578_bib29","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1111\/j.1440-1754.2010.01990.x","article-title":"Low defaecation frequency in Taiwanese adolescents: association with dietary intake, physical activity and sedentary behaviour","volume":"47","author":"Chien","year":"2011","journal-title":"J\u00a0Paediatr Child Health"},{"issue":"1","key":"10.1016\/j.eclinm.2024.102578_bib30","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1093\/tropej\/fmq039","article-title":"Prevalence of functional gastrointestinal diseases in a cohort of Sri Lankan adolescents: comparison between Rome II and Rome III criteria","volume":"57","author":"Devanarayana","year":"2011","journal-title":"J\u00a0Trop Pediatr"},{"issue":"6","key":"10.1016\/j.eclinm.2024.102578_bib31","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1093\/tropej\/fmr013","article-title":"Constipation during and after the civil war in Sri Lanka: a paediatric study","volume":"57","author":"Rajindrajith","year":"2011","journal-title":"J\u00a0Trop Pediatr"},{"issue":"2","key":"10.1016\/j.eclinm.2024.102578_bib32","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.jcma.2011.01.012","article-title":"Constipation in Taiwan elementary school students: a nationwide survey","volume":"74","author":"Wu","year":"2011","journal-title":"J\u00a0Chin Med Assoc"},{"issue":"2","key":"10.1016\/j.eclinm.2024.102578_bib33","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1097\/MPG.0b013e3182125388","article-title":"Prevalence and associated factors of functional gastrointestinal disorders and bowel habits in Chinese adolescents: a school-based study","volume":"53","author":"Zhou","year":"2011","journal-title":"J\u00a0Pediatr Gastroenterol Nutr"},{"issue":"4","key":"10.1016\/j.eclinm.2024.102578_bib34","doi-asserted-by":"crossref","first-page":"1211","DOI":"10.1007\/s11325-011-0635-5","article-title":"Functional gastrointestinal disorders among adolescents with poor sleep: a school-based study in Shanghai, China","volume":"16","author":"Zhou","year":"2012","journal-title":"Sleep Breath"},{"issue":"1","key":"10.1016\/j.eclinm.2024.102578_bib35","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1136\/adc.2009.173716","article-title":"Constipation in children: an epidemiological study in Sri Lanka using Rome III criteria","volume":"97","author":"Rajindrajith","year":"2012","journal-title":"Arch Dis Child"},{"issue":"1","key":"10.1016\/j.eclinm.2024.102578_bib36","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1097\/MPG.0b013e31824741ce","article-title":"Socioenvironmental factors associated with constipation in Hong Kong children and Rome III criteria","volume":"55","author":"Tam","year":"2012","journal-title":"J\u00a0Pediatr Gastroenterol Nutr"},{"issue":"1","key":"10.1016\/j.eclinm.2024.102578_bib37","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1111\/ped.12194","article-title":"Use of Rome II versus Rome III criteria for diagnosis of functional constipation in young children","volume":"56","author":"Osatakul","year":"2014","journal-title":"Pediatr Int"},{"issue":"2","key":"10.1016\/j.eclinm.2024.102578_bib38","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0090193","article-title":"Physical activity and constipation in Hong Kong adolescents","volume":"9","author":"Huang","year":"2014","journal-title":"PLoS One"},{"issue":"4","key":"10.1016\/j.eclinm.2024.102578_bib39","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1097\/MPG.0000000000000249","article-title":"Association between child maltreatment and constipation: a school-based survey using Rome III criteria","volume":"58","author":"Rajindrajith","year":"2014","journal-title":"J\u00a0Pediatr Gastroenterol Nutr"},{"issue":"4","key":"10.1016\/j.eclinm.2024.102578_bib40","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1007\/s12664-016-0680-x","article-title":"Prevalence of functional gastrointestinal disorders among adolescents in Delhi based on Rome III criteria: a school-based survey","volume":"35","author":"Bhatia","year":"2016","journal-title":"Indian J Gastroenterol"},{"issue":"8","key":"10.1016\/j.eclinm.2024.102578_bib41","doi-asserted-by":"crossref","first-page":"1262","DOI":"10.3346\/jkms.2016.31.8.1262","article-title":"Risk factors for functional constipation in young children attending daycare centers","volume":"31","author":"Park","year":"2016","journal-title":"J\u00a0Korean Med Sci"},{"issue":"2","key":"10.1016\/j.eclinm.2024.102578_bib42","first-page":"393","article-title":"Fast foods--are they a risk factor for functional gastrointestinal disorders?","volume":"25","author":"Shau","year":"2016","journal-title":"Asia Pac J Clin Nutr"},{"issue":"8","key":"10.1016\/j.eclinm.2024.102578_bib43","doi-asserted-by":"crossref","first-page":"1175","DOI":"10.21474\/IJAR01\/5170","article-title":"Prevalence and factors associated with functional constipation among childrem attending well baby clinic in Aladel primary health care center in Makkah Al-Mukarramah","volume":"5","author":"AlGhamdi","year":"2016","journal-title":"Int J Adv Res"},{"issue":"1","key":"10.1016\/j.eclinm.2024.102578_bib44","first-page":"118","article-title":"Dietary intake, physical activity, and time management are associated with constipation in preschool children in Japan","volume":"26","author":"Asakura","year":"2017","journal-title":"Asia Pac J Clin Nutr"},{"issue":"5","key":"10.1016\/j.eclinm.2024.102578_bib45","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1097\/MPG.0000000000001332","article-title":"Constipation and constipation-predominant irritable bowel syndrome: a comparative study using Rome III criteria","volume":"64","author":"Rajindrajith","year":"2017","journal-title":"J\u00a0Pediatr Gastroenterol Nutr"},{"issue":"12","key":"10.1016\/j.eclinm.2024.102578_bib46","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0208571","article-title":"Prevalence of functional constipation among Palestinian preschool children and the relation to stressful life events","volume":"13","author":"Froon-Torenstra","year":"2018","journal-title":"PLoS One"},{"issue":"1","key":"10.1016\/j.eclinm.2024.102578_bib47","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1186\/s12876-018-0873-0","article-title":"Epidemiology of paediatric constipation in Indonesia and its association with exposure to stressful life events","volume":"18","author":"Oswari","year":"2018","journal-title":"BMC Gastroenterol"},{"issue":"1","key":"10.1016\/j.eclinm.2024.102578_bib48","doi-asserted-by":"crossref","first-page":"882","DOI":"10.1186\/s13104-018-3990-5","article-title":"Association between cesarean section and constipation in infants: the Japan Environment and Children's Study (JECS)","volume":"11","author":"Yoshida","year":"2018","journal-title":"BMC Res Notes"},{"issue":"1","key":"10.1016\/j.eclinm.2024.102578_bib49","first-page":"1","article-title":"Obesity and functional constipation in children","volume":"58","author":"Yuwanita","year":"2018","journal-title":"Indonesian J Pediatrics and Perinat Med"},{"issue":"9","key":"10.1016\/j.eclinm.2024.102578_bib50","first-page":"1179","article-title":"[Epidemiologic survey on the prevalence and distribution of infants' common gastrointestinal symptoms in 7 cities in China: a population-based study]","volume":"39","author":"Ji","year":"2018","journal-title":"Zhonghua Liuxingbingxue Zazhi"},{"issue":"4","key":"10.1016\/j.eclinm.2024.102578_bib51","first-page":"4870","article-title":"Identification of prevalence of constipation in infants aged 0-12 months in rural areas","volume":"19","author":"Caglar","year":"2019","journal-title":"Rural Rem Health"},{"issue":"1","key":"10.1016\/j.eclinm.2024.102578_bib52","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1186\/s12887-019-1652-y","article-title":"Functional constipation in infancy and early childhood: epidemiology, risk factors, and healthcare consultation","volume":"19","author":"Walter","year":"2019","journal-title":"BMC Pediatr"},{"issue":"6","key":"10.1016\/j.eclinm.2024.102578_bib53","first-page":"220","article-title":"Psychological stress, family environment, and constipation in Japanese children: the Toyama Birth Cohort Study","volume":"29","author":"Yamada","year":"2019","journal-title":"J\u00a0Epidemiol"},{"issue":"1","key":"10.1016\/j.eclinm.2024.102578_bib54","doi-asserted-by":"crossref","first-page":"38","DOI":"10.3177\/jnsv.65.38","article-title":"The relationship between functional constipation and dietary habits in school-age Japanese children","volume":"65","author":"Okuda","year":"2019","journal-title":"J\u00a0Nutr Sci Vitaminol"},{"key":"10.1016\/j.eclinm.2024.102578_bib55","doi-asserted-by":"crossref","first-page":"267","DOI":"10.2147\/CEG.S256276","article-title":"National prevalence of functional gastrointestinal disorders in Jordanian children","volume":"13","author":"Altamimi","year":"2020","journal-title":"Clin Exp Gastroenterol"},{"issue":"8","key":"10.1016\/j.eclinm.2024.102578_bib56","doi-asserted-by":"crossref","first-page":"2443","DOI":"10.1007\/s00431-021-04059-2","article-title":"The frequency of and factors affecting functional gastrointestinal disorders in infants that presented to tertiary care hospitals","volume":"180","author":"Beser","year":"2021","journal-title":"Eur J Pediatr"},{"issue":"1","key":"10.1016\/j.eclinm.2024.102578_bib57","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.pedneo.2020.08.009","article-title":"Low prevalence of infantile functional gastrointestinal disorders (FGIDs) in a multi-ethnic Asian population","volume":"62","author":"Chew","year":"2021","journal-title":"Pediatr Neonatol"},{"issue":"1","key":"10.1016\/j.eclinm.2024.102578_bib58","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1186\/s12887-021-02610-6","article-title":"Prevalence of functional gastrointestinal disorders in infants and young children in China","volume":"21","author":"Huang","year":"2021","journal-title":"BMC Pediatr"},{"key":"10.1016\/j.eclinm.2024.102578_bib59","article-title":"The effect of using Rome IV criteria on the prevalence of functional abdominal pain disorders and functional constipation among children of the western region of Saudi arabia","volume":"8","author":"Khayat","year":"2021","journal-title":"Glob Pediatr Health"},{"issue":"27","key":"10.1016\/j.eclinm.2024.102578_bib60","doi-asserted-by":"crossref","DOI":"10.1097\/MD.0000000000026442","article-title":"Psychological factors to predict chronic diarrhea and constipation in Korean high school students","volume":"100","author":"Kim","year":"2021","journal-title":"Medicine (Baltimore)"},{"issue":"5","key":"10.1016\/j.eclinm.2024.102578_bib61","first-page":"697","article-title":"Investigation of dyspepsia in school-age children in Changning District of Shanghai, China and its association with dietary patterns","volume":"48","author":"Fang","year":"2021","journal-title":"Fudan Univ J Med Sci"},{"issue":"1","key":"10.1016\/j.eclinm.2024.102578_bib62","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1186\/s12887-022-03378-z","article-title":"Prevalence and risk factors of functional gastrointestinal disorders in Vietnamese infants and young children","volume":"22","author":"Chia","year":"2022","journal-title":"BMC Pediatr"},{"issue":"7","key":"10.1016\/j.eclinm.2024.102578_bib63","first-page":"647","article-title":"[Characteristics and risk factors of functional constipation in children aged 0-4 years in Xi 'an]","volume":"60","author":"Li","year":"2022","journal-title":"Zhonghua Er Ke Za Zhi"},{"issue":"7","key":"10.1016\/j.eclinm.2024.102578_bib64","doi-asserted-by":"crossref","first-page":"1209","DOI":"10.1111\/jpc.15950","article-title":"Prevalence of functional abdominal pain disorders and functional constipation in adolescents","volume":"58","author":"Siajunboriboon","year":"2022","journal-title":"J\u00a0Paediatr Child Health"},{"key":"10.1016\/j.eclinm.2024.102578_bib65","doi-asserted-by":"crossref","first-page":"993032","DOI":"10.3389\/fped.2022.993032","article-title":"A\u00a0population-based study on prevalence and predisposing risk factors of infant functional gastrointestinal disorders in a single center in Southern Fujian","volume":"10","author":"Huang","year":"2022","journal-title":"Front Pediatr"},{"issue":"1","key":"10.1016\/j.eclinm.2024.102578_bib66","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.bpg.2010.12.010","article-title":"Epidemiology of constipation in children and adults: a systematic review","volume":"25","author":"Mugie","year":"2011","journal-title":"Best Pract Res Clin Gastroenterol"},{"key":"10.1016\/j.eclinm.2024.102578_bib67","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/j.jpeds.2018.02.029","article-title":"Prevalence of Functional Defecation Disorders in children: a systematic review and meta-analysis","volume":"198","author":"Koppen","year":"2018","journal-title":"J\u00a0Pediatr"},{"key":"10.1016\/j.eclinm.2024.102578_bib68","doi-asserted-by":"crossref","DOI":"10.1155\/2014\/532734","article-title":"Epidemiology characteristics of constipation for general population, pediatric population, and elderly population in China","volume":"2014","author":"Chu","year":"2014","journal-title":"Gastroenterol Res Pract"},{"issue":"6","key":"10.1016\/j.eclinm.2024.102578_bib69","doi-asserted-by":"crossref","first-page":"1443","DOI":"10.1053\/j.gastro.2016.02.016","article-title":"Childhood functional gastrointestinal disorders: neonate\/toddler","volume":"150","author":"Benninga","year":"2016","journal-title":"Gastroenterology"},{"issue":"1","key":"10.1016\/j.eclinm.2024.102578_bib70","doi-asserted-by":"crossref","first-page":"123","DOI":"10.5056\/jnm18035","article-title":"Functional chronic constipation: Rome III criteria versus Rome IV criteria","volume":"25","author":"Russo","year":"2019","journal-title":"J\u00a0Neurogastroenterol Motil"},{"issue":"10","key":"10.1016\/j.eclinm.2024.102578_bib71","doi-asserted-by":"crossref","first-page":"2401","DOI":"10.1111\/j.1572-0241.2006.00771.x","article-title":"Epidemiology of childhood constipation: a systematic review","volume":"101","author":"van den Berg","year":"2006","journal-title":"Am J Gastroenterol"},{"issue":"9","key":"10.1016\/j.eclinm.2024.102578_bib72","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1016\/j.nutres.2012.07.003","article-title":"Potential mechanisms for the emerging link between obesity and increased intestinal permeability","volume":"32","author":"Teixeira","year":"2012","journal-title":"Nutr Res"},{"issue":"1","key":"10.1016\/j.eclinm.2024.102578_bib73","doi-asserted-by":"crossref","first-page":"84","DOI":"10.3164\/jcbn.22-143","article-title":"Relationships between body mass index and constipation, gastroesophageal reflux disease, stool forms based on the Bristol Stool Form Scale, and education level: results from an internet survey in Japan","volume":"73","author":"Ogasawara","year":"2023","journal-title":"J\u00a0Clin Biochem Nutr"},{"issue":"2","key":"10.1016\/j.eclinm.2024.102578_bib74","first-page":"151","article-title":"Obesity and functional constipation; a community-based study in Iran","volume":"18","author":"Pourhoseingholi","year":"2009","journal-title":"J\u00a0Gastrointestin Liver Dis"},{"issue":"6","key":"10.1016\/j.eclinm.2024.102578_bib75","doi-asserted-by":"crossref","first-page":"1878","DOI":"10.1038\/s41390-023-02711-1","article-title":"The relationship between functional constipation and overweight\/obesity in children: a systematic review and meta-analysis","volume":"94","author":"Wang","year":"2023","journal-title":"Pediatr Res"},{"key":"10.1016\/j.eclinm.2024.102578_bib76","article-title":"Association of sleep duration with chronic constipation among adult men and women: findings from the national health and nutrition examination survey (2005-2010)","volume":"13","author":"Yang","year":"2022","journal-title":"Front Neurol"},{"issue":"38","key":"10.1016\/j.eclinm.2024.102578_bib77","doi-asserted-by":"crossref","first-page":"4297","DOI":"10.3748\/wjg.v24.i38.4297","article-title":"Circadian rhythms in the pathogenesis of gastrointestinal diseases","volume":"24","author":"Codoner-Franch","year":"2018","journal-title":"World J Gastroenterol"},{"issue":"3","key":"10.1016\/j.eclinm.2024.102578_bib78","first-page":"159","article-title":"Psychological disorders in patients with chronic constipation","volume":"4","author":"Hosseinzadeh","year":"2011","journal-title":"Gastroenterol Hepatol Bed Bench"},{"issue":"2","key":"10.1016\/j.eclinm.2024.102578_bib79","doi-asserted-by":"crossref","first-page":"e27","DOI":"10.1097\/MPG.0000000000003653","article-title":"Prevalence and risk factors of functional gastrointestinal disorders: a cross-sectional study in Italian infants and young children","volume":"76","author":"Scarpato","year":"2023","journal-title":"J\u00a0Pediatr Gastroenterol Nutr"},{"issue":"Suppl 2","key":"10.1016\/j.eclinm.2024.102578_bib80","doi-asserted-by":"crossref","first-page":"S88","DOI":"10.1038\/sj.ejcn.1601907","article-title":"Mild dehydration: a risk factor of constipation?","volume":"57","author":"Arnaud","year":"2003","journal-title":"Eur J Clin Nutr"},{"issue":"23","key":"10.1016\/j.eclinm.2024.102578_bib81","doi-asserted-by":"crossref","DOI":"10.1002\/mnfr.201801187","article-title":"Abundance of probiotics and butyrate-production microbiome manages constipation via short-chain fatty acids production and hormones secretion","volume":"63","author":"Zhuang","year":"2019","journal-title":"Mol Nutr Food Res"},{"issue":"11","key":"10.1016\/j.eclinm.2024.102578_bib82","doi-asserted-by":"crossref","first-page":"1621","DOI":"10.1016\/S0002-8223(02)90346-9","article-title":"Dietary reference intakes for energy, carbohydrate, fiber, fat, fatty acids, cholesterol, protein and amino acids.(Commentary)","volume":"102","author":"Trumbo","year":"2002","journal-title":"J\u00a0Am Diet Assoc"}],"container-title":["eClinicalMedicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2589537024001573?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2589537024001573?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,17]],"date-time":"2025-10-17T21:51:54Z","timestamp":1760737914000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2589537024001573"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,5]]},"references-count":82,"alternative-id":["S2589537024001573"],"URL":"https:\/\/doi.org\/10.1016\/j.eclinm.2024.102578","relation":{},"ISSN":["2589-5370"],"issn-type":[{"value":"2589-5370","type":"print"}],"subject":[],"published":{"date-parts":[[2024,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Prevalence and determinants of constipation in children in Asia: a systematic review and meta-analysis","name":"articletitle","label":"Article Title"},{"value":"eClinicalMedicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.eclinm.2024.102578","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Author(s). Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"102578"}}